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DR DAVID GREENE
R3 STEM CELL
Can Stem Cell Therapy Treat Different
Types of Sciatic Nerve Pain
www.r3stemcell.co
What is Sciatica
Pain?
Sciatica is a sharp shooting pain that occurs due to
the damage or compression of the sciatic nerve in
the lumbar area. The pain radiates along the nerve’s
route; from the lower back to the hip and outer leg
and finally to the knee joint. Except for some rare
cases, it usually affects only one side of the body.
Sciatic pain usually resolves within weeks without
the need for surgical treatment. However, in more
severe instances like a herniated disk, sciatica pain
can extend up to the foot, cause bladder and bowel
issues, and might need serious treatment.
Common Symptoms of Sciatica:
The compression causes
severe pain in the affected
leg, especially in the calf
region. it could be constant or
irregular depending on the
severity of the damage.
Pain:
The pain felt throughout
the leg can leave the
affected foot and leg
feeling weak.
Patients often report
feeling numbness or
pinpricking sensation
along the channel of the
sciatica nerve in the
affected leg.
Altered sensation Fragility
Different Types of Sciatica:
Acute sciatica: Chronic sciatica: Alternating Sciatica: Bilateral Sciatic
When the symptoms
have not been older than
4-8 weeks, the pain is
categorized as acute
sciatica. This type of
sciatic nerve pain can be
easily managed at home
with over-the-counter
medicines and exercise.
If sciatic pain continues
after 8 weeks it is called
chronic sciatica. This kind
of pain does not subside
with self-management.
Proper physiotherapy
sessions are required,
surgical treatment could
also be needed for severe
cases.
Sciatica that affects
both legs alternately is
known as alternating
sciatica. This form of
sciatica is unusual and
can be caused by
sacroiliac joint
degeneration.
Bilateral sciatica is one of
those rare cases that affect
both legs at the same time.
Two different reasons can
cause bilateral sciatica.
– Degenerative changes in
the vertebrae or disc at
multiple spinal levels.
– Serious disorders like
cauda equina syndrome.
Causes of Sciatic Nerve Pain:
Disk Issues
Space Occupying
Lesion
Chronic Diseases Injury or Trauma
Herniated or slipped disks
are the chief contributors
of sciatic pain. Slipped
discs are very common,
around 4 % of people face
issues related to a slipped
disc, globally. Factors like
bad posture, accidents,
strenuous activity, sports
injuries, and repetitive
physical stress can lead to
disk bulging or slipping.
Narrowing of the
spinal canal due to
clots, tumors of
bone overgrowth
generates pressure
on the lumbar nerve
root or the sciatic
nerve itself.
Diabetes is one of the
reasons why people
suffer from sciatic
nerve pain. Over time
constant high blood
glucose levels can
damage the nerve fibers
throughout the body
causing neuropathy.
Accidents are one of
the leading causes of
sciatic pain. Lower back
injuries and traumas are
always dangerous. They
cause degeneration of
discs which in turn
causes nerve damage.
Injuries impact muscle
strength as well.
Risk Factors of Sciatic Nerve Pain:
Pregnancy Postural issues Aging Occupation
Hormonal changes in
pregnancy cause
ligament laxity that
hold vertebrae, the
loosening of the
ligament might
contribute to bugling
or slipping of disk.
Most of the
postural issues are
related to habits. In
men, habits like
carrying a wallet in
the back pocket and
bike riding can lead
to sciatic pain.
Muscle compression
or shortening with age
can cause sciatica.
Age-related changes
in the spine due to
weakness of bones
and muscle
shortening with age
can cause
A strenuous job
can increase the
risks of sciatica.
Where physical
strength is always
required.
Gym
Risk Factors of Sciatic Nerve Pain:
Obesity Inactivity Smoking
Excessive weight
gain causes stress
over the lumbar area
which decreases the
space between the
lumbar vertebrae.
The lack of space in
the lumbar
vertebrae inspires
irritation in the
nerve.
Sitting for a long
time has many
negative impacts,
especially on the
lower back. A
sedentary lifestyle
is riskier.
Not following proper
postural instructions
while doing weight
exercises in the gym
can damage the
nerves.
Nicotine can
damage spinal
tissues and
weaken the
bones.
Effects of Sciatic Nerve Pain
Numbness in the nerve
decreased proprioception,
which is the ability of
muscles to detect
movement, action, and
location. Proprioception is
what allows us to follow a
certain direction and
coordinate in balance.
When the body avoids applying pressure
to the injured area (in this case, the lower
back), it tempers with the natural
alignment of the body causing Neck
pains, Headaches, exhaustion, and
severe cases of hump between the
shoulders. This postural distortion is also
called “overprotective posture.
When the nerve is compromised it
reduces our reflexes to a certain
degree. For example, the knee-jerk
and ability to flex the foot upward
is withdrawn.
Losing balance Postural Distortion Reflex decline
Is Stem Cell Therapy Beneficial for Sciatic Pain?
The painkiller dosage for sciatica starts from at
least 1000mg and these can easily be harmful
in the long run. Since sciatica is a neurological
disorder, treating it with traditional
medications can prove ineffective in some
cases. The sciatic pain progresses with time. As
regenerative medicine Stem Cell therapy can
help improve the body’s natural ability to
repair and regenerate non-surgically. It can
also prevent the progression of sciatic pain.
Cell-based therapy treats various diseases by
injecting cellular material into the patient’s body.
This cellular material can be obtained from
different sources but the most promising in the
case of MND are Umbilical cord stem cells and
amniotic fluid stem cells. Unlike cells extracted
from bone marrow or fat tissues, umbilical cord
and amniotic stem cells are younger and
unclaimed, this is why they do not need much
manipulation before administering them to the
patient.
Regenerative Medicine Stem Cell Sources
THANK YOU
www.r3stemcell.co

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  • 1. DR DAVID GREENE R3 STEM CELL Can Stem Cell Therapy Treat Different Types of Sciatic Nerve Pain www.r3stemcell.co
  • 2. What is Sciatica Pain? Sciatica is a sharp shooting pain that occurs due to the damage or compression of the sciatic nerve in the lumbar area. The pain radiates along the nerve’s route; from the lower back to the hip and outer leg and finally to the knee joint. Except for some rare cases, it usually affects only one side of the body. Sciatic pain usually resolves within weeks without the need for surgical treatment. However, in more severe instances like a herniated disk, sciatica pain can extend up to the foot, cause bladder and bowel issues, and might need serious treatment.
  • 3. Common Symptoms of Sciatica: The compression causes severe pain in the affected leg, especially in the calf region. it could be constant or irregular depending on the severity of the damage. Pain: The pain felt throughout the leg can leave the affected foot and leg feeling weak. Patients often report feeling numbness or pinpricking sensation along the channel of the sciatica nerve in the affected leg. Altered sensation Fragility
  • 4. Different Types of Sciatica: Acute sciatica: Chronic sciatica: Alternating Sciatica: Bilateral Sciatic When the symptoms have not been older than 4-8 weeks, the pain is categorized as acute sciatica. This type of sciatic nerve pain can be easily managed at home with over-the-counter medicines and exercise. If sciatic pain continues after 8 weeks it is called chronic sciatica. This kind of pain does not subside with self-management. Proper physiotherapy sessions are required, surgical treatment could also be needed for severe cases. Sciatica that affects both legs alternately is known as alternating sciatica. This form of sciatica is unusual and can be caused by sacroiliac joint degeneration. Bilateral sciatica is one of those rare cases that affect both legs at the same time. Two different reasons can cause bilateral sciatica. – Degenerative changes in the vertebrae or disc at multiple spinal levels. – Serious disorders like cauda equina syndrome.
  • 5. Causes of Sciatic Nerve Pain: Disk Issues Space Occupying Lesion Chronic Diseases Injury or Trauma Herniated or slipped disks are the chief contributors of sciatic pain. Slipped discs are very common, around 4 % of people face issues related to a slipped disc, globally. Factors like bad posture, accidents, strenuous activity, sports injuries, and repetitive physical stress can lead to disk bulging or slipping. Narrowing of the spinal canal due to clots, tumors of bone overgrowth generates pressure on the lumbar nerve root or the sciatic nerve itself. Diabetes is one of the reasons why people suffer from sciatic nerve pain. Over time constant high blood glucose levels can damage the nerve fibers throughout the body causing neuropathy. Accidents are one of the leading causes of sciatic pain. Lower back injuries and traumas are always dangerous. They cause degeneration of discs which in turn causes nerve damage. Injuries impact muscle strength as well.
  • 6. Risk Factors of Sciatic Nerve Pain: Pregnancy Postural issues Aging Occupation Hormonal changes in pregnancy cause ligament laxity that hold vertebrae, the loosening of the ligament might contribute to bugling or slipping of disk. Most of the postural issues are related to habits. In men, habits like carrying a wallet in the back pocket and bike riding can lead to sciatic pain. Muscle compression or shortening with age can cause sciatica. Age-related changes in the spine due to weakness of bones and muscle shortening with age can cause A strenuous job can increase the risks of sciatica. Where physical strength is always required.
  • 7. Gym Risk Factors of Sciatic Nerve Pain: Obesity Inactivity Smoking Excessive weight gain causes stress over the lumbar area which decreases the space between the lumbar vertebrae. The lack of space in the lumbar vertebrae inspires irritation in the nerve. Sitting for a long time has many negative impacts, especially on the lower back. A sedentary lifestyle is riskier. Not following proper postural instructions while doing weight exercises in the gym can damage the nerves. Nicotine can damage spinal tissues and weaken the bones.
  • 8. Effects of Sciatic Nerve Pain Numbness in the nerve decreased proprioception, which is the ability of muscles to detect movement, action, and location. Proprioception is what allows us to follow a certain direction and coordinate in balance. When the body avoids applying pressure to the injured area (in this case, the lower back), it tempers with the natural alignment of the body causing Neck pains, Headaches, exhaustion, and severe cases of hump between the shoulders. This postural distortion is also called “overprotective posture. When the nerve is compromised it reduces our reflexes to a certain degree. For example, the knee-jerk and ability to flex the foot upward is withdrawn. Losing balance Postural Distortion Reflex decline
  • 9. Is Stem Cell Therapy Beneficial for Sciatic Pain? The painkiller dosage for sciatica starts from at least 1000mg and these can easily be harmful in the long run. Since sciatica is a neurological disorder, treating it with traditional medications can prove ineffective in some cases. The sciatic pain progresses with time. As regenerative medicine Stem Cell therapy can help improve the body’s natural ability to repair and regenerate non-surgically. It can also prevent the progression of sciatic pain. Cell-based therapy treats various diseases by injecting cellular material into the patient’s body. This cellular material can be obtained from different sources but the most promising in the case of MND are Umbilical cord stem cells and amniotic fluid stem cells. Unlike cells extracted from bone marrow or fat tissues, umbilical cord and amniotic stem cells are younger and unclaimed, this is why they do not need much manipulation before administering them to the patient. Regenerative Medicine Stem Cell Sources