The 4th annual Python Web Conf (#PWC2022) was a virtual event designed to promote best practices for hard web production problems. It featured international experts presenting on topics such as Django, CI/CD, Containers, Serverless, REST APIs, web security, microservices and more! The highly engaging format featured 90 speakers, 6 tracks (including 80 talks and 4 tutorials) and took place virtually from March 21-25, 2022 on LoudSwarm by Six Feet Up. More information about the 2022 conference can be found at: 2022.pythonwebconf.com.