SlideShare a Scribd company logo
Melissa Inman MS, PhD
3620 South 17th
, Lincoln, NE 68502 * 402.613.6472 * inman.melissa@yahoo.com
Publications and Research Papers
· W.W. Laegreid, M. Stone-Marschat, A. Skowronek, and T. Burrage: Infection of Endothelial Cells by African Horsesickness
Viruses. Bluetongue, African Horsesickness, and Related Orbiviruses. Walton and Osburn, CRC Press. 1992 p. 807-814.
· Laegreid WW, Burrage TG, Stone-Marschat M, and Skowronek A. (1992) Electron microscopic evidence for endothelial
infection by African horsesickness virus. Vet. Pathol. 29: 554-556.
· Burrage TG, Trevejo R, Stone-Marschat M, and Laegreid WW. (1993) Neutralizing epitopes of African Horsesickness virus
serotype 4 are located on VP2. Virology. 196: 799-803.
· Laegreid WW, Skowronek A, Stone-Marschat M, and Burrage T. (1993) Characterization of virulence variants of African
Horsesickness virus. Virology. 195: 836-839.
· Stone-Marschat M, Carville A, Skowronek A, and Laegreid WW. (1994) Detection of African Horsesickness virus by
reverse transcription-polymerase chain reaction. J. Clin. Microbiol. 32: 697-70
· Skowronek AJ, LoFranco L, Stone-Marschat MA, Burrage TG, Rebar AH, Laegreid WW. (1995) Clinical pathology and
homeostatic abnormalities in experimental African Horsesickness. Vet Path. 32:112-121.
· Stone-Marschat M, Moss S, Burrage T, Barber M, Roy P, Laegreid W. (1996) Immunization with VP2 is sufficient for
protection against lethal challenge with African Horsesickness virus type 4. Virology 220: 219-222.
· Hussein A, Stone-Marschat M, Burrage T, Laegreid W. (1997) Comparative sequence analysis of genome segment 10 of
African Horsesickness virus type 4 to the cognate genes. J.Egypt.Vet.Med. Ass. 57, No.1:985-1000.
· Ciacci-Zanella, J. M. Stone, and C. Jones. 1999. The latency related gene of bovine herpesvirus 1 inhibits programmed
cell death induced by C6-ceramide or fumonisin B1. J. Virology, 73:9734-9740.
· Perng, G.-C., C. Jones, J. Ciacci-Zanella, M. Inman, G. Henderson, S.M. Slanina, A. Yukht, H. Ghiasi, A. B. Nesburn, and S. L.
Wechsler. 2000. Virus induced neuronal apoptosis blocked by the herpes simplex virus latency associated transcript (LAT).
Science 287:1500-1503.
· Jones, C., T.J. Newby, T. Holt, A. Doster, M. Stone, J. Ciacci-Zanella, C.J. Webster, and M. W. Jackwood. 2000. Analysis
of latency in cattle after inoculation with a temperature sensitive mutant of bovine herpesvirus 1 (RLB106). Vaccine 73:9734-
9740.
· Inman, M., Y. Zhange, V. Geiser, and C. Jones. 2001. The zinc ring finger of bovine herpes virus 1 encoded bICP0 is
necessary for transcriptional regulation and infection. J. General Virology, 82:483-492.
· Inman, M., Perng, G.-C., G. Henderson, A. B. Nesburn, and S. L. Wechsler, and C. Jones. 2001. Region of Herpes Simplex
Virus Type 1 Latency-Associated Transcript Sufficient for Wild-Type Spontaneous Reactivation Promotes Cell Survival in Tissue
Culture. J. Virology, 75:3636-3646.
· Inman, M., L. Lovato, A. Doster and C. Jones. 2001. The latency related gene of bovine herpesvirus enhances ocular
shedding in acutely infected calves. J. Virology, 75:8507-8515.
· Guey-Chuen Perng, B. Maguen, L. Jing, K.R. Mott, N. Osorio, S.M. Slanina, A. Yukht, H. Ghiasi, A.B. Nesburn, M. Inman, G.
Henderson, C. Jones, and S.L. Wechsler. 2002. A gene capable of blocking apoptosis can substitute for the herpes simplex virus
type 1 LAT gene and restore wild type reactivation levels. J. Virology, 76:1224-1235.
· Inman, M., L. Lovato, A. Doster, and C. Jones. 2002. A mutation in the latency related gene of bovine herpesvirus 1
disrupts the latency-reactivation cycle in calves. J. Virology, 76:6771-6779.
· Perng,G.-C., B. Maguen, L. Jin, K.R. Mott, S.M. Slanina, A. Yukht, H. Ghiasi, N. Osorio, H.K. Hamdi, A.B. Nesburn, G.
Henderson, M. Inman, C. Jones, and S.L. Wechsler. 2002. A novel herpes simplex virus type 1 (HSV-1) transcript (AL-RNA)
antisense to the 5’ end of LAT (latency) associated transcript) produces a protein in infected rabbits. J. Virology, 76:8003-8010.
· Geiser, G., M. Inman, Y. Zhang, and C. Jones. 2002. The latency related (LR) gene of bovine herpes virus 1 (BHV-1) can
inhibit the ability of bICP0 to activate productive infection. J. General Virology, 83:2965 – 2971.
· Lovato, L., M. Inman, G. Henderson, A. Doster., and C. Jones, C. 2003. Infection of cattle with a bovine herpesvirus 1
(BHV-1) strain that contains a mutation in the latency related gene leads to increased apoptosis in trigeminal ganglia during the
transition from acute infection to latency. J. Virology, 77:4848-4857.
· Jiang, Y., M. Inman, Y. Zhang, N. Aleman-Posadas, and C. Jones. 2004. A mutation in the latency related gene of bovine
herpesvirus 1 (BHV-1) inhibits protein expression of a protein from open reading frame 2 (ORF2) and an adjacent reading frame
during productive infection. J. Virology, 78:3184-3189.
· Inman, M. and C. Jones. 2004. Identification of a novel bovine herpesvirus 1 (BHV-1) transcript containing a small open
reading frame (ORF-E) that is expressed in trigeminal ganglia of latently infected calves. J. Virology, 78 (10):5438-47.
· Henderson, G., Zhang, Y., Inman, M., Jones, D., and Jones, C. 2004. Infected cell protein 0 encoded by bovine
herpesvirus 1 can activate caspase 3 when overexpressed in transfected cells. J. Gen Virol, Dec; 85 (pt 12) 3511-6.
· Perez, S., M. Inman, A. Doster, and C. Jones. 2005. The latency related gene encoded by bovine herpesvirus 1 promotes
virus growth and reactivation from latency in tonsils of infected calves. J. Clinical Microbiology. Jan; 43(1), 393-401.
Melissa Inman MS, PhD
3620 South 17th
, Lincoln, NE 68502 * 402.613.6472 * inman.melissa@yahoo.com
· Peng, W., G. Henderson, M. Inman, L., BenMohamed, G. Perng, S. Wechsler, and C. Jones. 2005. The Locus
encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression
in productively infected neuroblastoma cells and trigeminal ganglia of acutely infected mice. J. Virology. May; 79(10), 6162-
6171.
· Jones, C., Inman, M., Peng, W., Henderson, G., Doster, A., Perng, GC. and AK Angeletti. 2005. The herpes sinplex virus
type 1 locus that encodes the latency-associated transcript enhances the frequency of encephalitis in male BALB/c mice. J.
Virology, Nov.; 79(22):14465-14469.
· Meyer, F., Perez, S., Geiser, V., Sintek, M., Inman, M., and C. Jones. 2007. A protein encoded by the bovine herpesvirus 1
latency-related gene interacts with specific cellular regulatory proteins, including CCAAT enhancer binding protein alpha. J.
Virology, Jan.; 81(1), 59-67.
· Perez, S., Meyer, F., Henderson, G., Jiang, Y., Sherman, S., Doster, A., Inman, M., and C. Jones. 2007. A protein encoded
ny the bovine herpesvirus 1 open reading frame E gene induces neurite-like morphological changes in mouse neuroblastoma
cells and is expressed in trigeminal ganglionic neurons. J. Neurovirology, April; 13(2):139-149.
· Inman, M., M. Ficken, and T. Miller. 2006 Development of a Newcastle Disease Virus Mucosal Challenge Model using a
Lentogenic Strain and Detection by Realtime Reverse Transcriptase Polymerase Chain Reaction (rtRT-PCR). AVMA –
Presentation 2006
· Rapp Gabrielson, V., G. Nitzel, M. Corinne Lenz, J. Czach, E. Wicklund, C. Mischnick, W. Isaacson, M. Ellsworth, S. Behan, T.
Yonkers, L. Taylor, S. Zager, M. Inman, and T. Schieber. 2010. Efficacy study of a USDA conditionally-licensed vaccine for
pandemic H1N1 (pH1N1) swine influenza virus. IPVS International Meeting – Abstract
· Pfannenstiel, MA, and M. Inman. 2012 Appropriateness of in Vitro Potency Tests or Consistency for Vaccine Stability
Studies. Developments in Biologicals, vol. 134: 414-148.
· Inman, M., Trygstad, L. and Pfannenstiel, M.A. 2012. Inactivation of Swine Influenza Virus with imidazolidinyl urea with
retention of hemagglutination activity. Proceedings of the 2012 CRWAD Annual Meeting
· Abraham, A., TerHune, T., Keil. D., Miller, T., Inman, I., Settje, T., and Kelly, B. 2015. In ovo and Spray Efficacy of a Novel
DNA Immunostimulant Against Avian Pathogenic Escherichia coli (APEC) Infections in Poultry. Avian Diseases

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Publications and Research Papers

  • 1. Melissa Inman MS, PhD 3620 South 17th , Lincoln, NE 68502 * 402.613.6472 * inman.melissa@yahoo.com Publications and Research Papers · W.W. Laegreid, M. Stone-Marschat, A. Skowronek, and T. Burrage: Infection of Endothelial Cells by African Horsesickness Viruses. Bluetongue, African Horsesickness, and Related Orbiviruses. Walton and Osburn, CRC Press. 1992 p. 807-814. · Laegreid WW, Burrage TG, Stone-Marschat M, and Skowronek A. (1992) Electron microscopic evidence for endothelial infection by African horsesickness virus. Vet. Pathol. 29: 554-556. · Burrage TG, Trevejo R, Stone-Marschat M, and Laegreid WW. (1993) Neutralizing epitopes of African Horsesickness virus serotype 4 are located on VP2. Virology. 196: 799-803. · Laegreid WW, Skowronek A, Stone-Marschat M, and Burrage T. (1993) Characterization of virulence variants of African Horsesickness virus. Virology. 195: 836-839. · Stone-Marschat M, Carville A, Skowronek A, and Laegreid WW. (1994) Detection of African Horsesickness virus by reverse transcription-polymerase chain reaction. J. Clin. Microbiol. 32: 697-70 · Skowronek AJ, LoFranco L, Stone-Marschat MA, Burrage TG, Rebar AH, Laegreid WW. (1995) Clinical pathology and homeostatic abnormalities in experimental African Horsesickness. Vet Path. 32:112-121. · Stone-Marschat M, Moss S, Burrage T, Barber M, Roy P, Laegreid W. (1996) Immunization with VP2 is sufficient for protection against lethal challenge with African Horsesickness virus type 4. Virology 220: 219-222. · Hussein A, Stone-Marschat M, Burrage T, Laegreid W. (1997) Comparative sequence analysis of genome segment 10 of African Horsesickness virus type 4 to the cognate genes. J.Egypt.Vet.Med. Ass. 57, No.1:985-1000. · Ciacci-Zanella, J. M. Stone, and C. Jones. 1999. The latency related gene of bovine herpesvirus 1 inhibits programmed cell death induced by C6-ceramide or fumonisin B1. J. Virology, 73:9734-9740. · Perng, G.-C., C. Jones, J. Ciacci-Zanella, M. Inman, G. Henderson, S.M. Slanina, A. Yukht, H. Ghiasi, A. B. Nesburn, and S. L. Wechsler. 2000. Virus induced neuronal apoptosis blocked by the herpes simplex virus latency associated transcript (LAT). Science 287:1500-1503. · Jones, C., T.J. Newby, T. Holt, A. Doster, M. Stone, J. Ciacci-Zanella, C.J. Webster, and M. W. Jackwood. 2000. Analysis of latency in cattle after inoculation with a temperature sensitive mutant of bovine herpesvirus 1 (RLB106). Vaccine 73:9734- 9740. · Inman, M., Y. Zhange, V. Geiser, and C. Jones. 2001. The zinc ring finger of bovine herpes virus 1 encoded bICP0 is necessary for transcriptional regulation and infection. J. General Virology, 82:483-492. · Inman, M., Perng, G.-C., G. Henderson, A. B. Nesburn, and S. L. Wechsler, and C. Jones. 2001. Region of Herpes Simplex Virus Type 1 Latency-Associated Transcript Sufficient for Wild-Type Spontaneous Reactivation Promotes Cell Survival in Tissue Culture. J. Virology, 75:3636-3646. · Inman, M., L. Lovato, A. Doster and C. Jones. 2001. The latency related gene of bovine herpesvirus enhances ocular shedding in acutely infected calves. J. Virology, 75:8507-8515. · Guey-Chuen Perng, B. Maguen, L. Jing, K.R. Mott, N. Osorio, S.M. Slanina, A. Yukht, H. Ghiasi, A.B. Nesburn, M. Inman, G. Henderson, C. Jones, and S.L. Wechsler. 2002. A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 LAT gene and restore wild type reactivation levels. J. Virology, 76:1224-1235. · Inman, M., L. Lovato, A. Doster, and C. Jones. 2002. A mutation in the latency related gene of bovine herpesvirus 1 disrupts the latency-reactivation cycle in calves. J. Virology, 76:6771-6779. · Perng,G.-C., B. Maguen, L. Jin, K.R. Mott, S.M. Slanina, A. Yukht, H. Ghiasi, N. Osorio, H.K. Hamdi, A.B. Nesburn, G. Henderson, M. Inman, C. Jones, and S.L. Wechsler. 2002. A novel herpes simplex virus type 1 (HSV-1) transcript (AL-RNA) antisense to the 5’ end of LAT (latency) associated transcript) produces a protein in infected rabbits. J. Virology, 76:8003-8010. · Geiser, G., M. Inman, Y. Zhang, and C. Jones. 2002. The latency related (LR) gene of bovine herpes virus 1 (BHV-1) can inhibit the ability of bICP0 to activate productive infection. J. General Virology, 83:2965 – 2971. · Lovato, L., M. Inman, G. Henderson, A. Doster., and C. Jones, C. 2003. Infection of cattle with a bovine herpesvirus 1 (BHV-1) strain that contains a mutation in the latency related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency. J. Virology, 77:4848-4857. · Jiang, Y., M. Inman, Y. Zhang, N. Aleman-Posadas, and C. Jones. 2004. A mutation in the latency related gene of bovine herpesvirus 1 (BHV-1) inhibits protein expression of a protein from open reading frame 2 (ORF2) and an adjacent reading frame during productive infection. J. Virology, 78:3184-3189. · Inman, M. and C. Jones. 2004. Identification of a novel bovine herpesvirus 1 (BHV-1) transcript containing a small open reading frame (ORF-E) that is expressed in trigeminal ganglia of latently infected calves. J. Virology, 78 (10):5438-47. · Henderson, G., Zhang, Y., Inman, M., Jones, D., and Jones, C. 2004. Infected cell protein 0 encoded by bovine herpesvirus 1 can activate caspase 3 when overexpressed in transfected cells. J. Gen Virol, Dec; 85 (pt 12) 3511-6. · Perez, S., M. Inman, A. Doster, and C. Jones. 2005. The latency related gene encoded by bovine herpesvirus 1 promotes virus growth and reactivation from latency in tonsils of infected calves. J. Clinical Microbiology. Jan; 43(1), 393-401.
  • 2. Melissa Inman MS, PhD 3620 South 17th , Lincoln, NE 68502 * 402.613.6472 * inman.melissa@yahoo.com · Peng, W., G. Henderson, M. Inman, L., BenMohamed, G. Perng, S. Wechsler, and C. Jones. 2005. The Locus encompassing the latency-associated transcript of herpes simplex virus type 1 interferes with and delays interferon expression in productively infected neuroblastoma cells and trigeminal ganglia of acutely infected mice. J. Virology. May; 79(10), 6162- 6171. · Jones, C., Inman, M., Peng, W., Henderson, G., Doster, A., Perng, GC. and AK Angeletti. 2005. The herpes sinplex virus type 1 locus that encodes the latency-associated transcript enhances the frequency of encephalitis in male BALB/c mice. J. Virology, Nov.; 79(22):14465-14469. · Meyer, F., Perez, S., Geiser, V., Sintek, M., Inman, M., and C. Jones. 2007. A protein encoded by the bovine herpesvirus 1 latency-related gene interacts with specific cellular regulatory proteins, including CCAAT enhancer binding protein alpha. J. Virology, Jan.; 81(1), 59-67. · Perez, S., Meyer, F., Henderson, G., Jiang, Y., Sherman, S., Doster, A., Inman, M., and C. Jones. 2007. A protein encoded ny the bovine herpesvirus 1 open reading frame E gene induces neurite-like morphological changes in mouse neuroblastoma cells and is expressed in trigeminal ganglionic neurons. J. Neurovirology, April; 13(2):139-149. · Inman, M., M. Ficken, and T. Miller. 2006 Development of a Newcastle Disease Virus Mucosal Challenge Model using a Lentogenic Strain and Detection by Realtime Reverse Transcriptase Polymerase Chain Reaction (rtRT-PCR). AVMA – Presentation 2006 · Rapp Gabrielson, V., G. Nitzel, M. Corinne Lenz, J. Czach, E. Wicklund, C. Mischnick, W. Isaacson, M. Ellsworth, S. Behan, T. Yonkers, L. Taylor, S. Zager, M. Inman, and T. Schieber. 2010. Efficacy study of a USDA conditionally-licensed vaccine for pandemic H1N1 (pH1N1) swine influenza virus. IPVS International Meeting – Abstract · Pfannenstiel, MA, and M. Inman. 2012 Appropriateness of in Vitro Potency Tests or Consistency for Vaccine Stability Studies. Developments in Biologicals, vol. 134: 414-148. · Inman, M., Trygstad, L. and Pfannenstiel, M.A. 2012. Inactivation of Swine Influenza Virus with imidazolidinyl urea with retention of hemagglutination activity. Proceedings of the 2012 CRWAD Annual Meeting · Abraham, A., TerHune, T., Keil. D., Miller, T., Inman, I., Settje, T., and Kelly, B. 2015. In ovo and Spray Efficacy of a Novel DNA Immunostimulant Against Avian Pathogenic Escherichia coli (APEC) Infections in Poultry. Avian Diseases