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Llinos GHarris - Curriculum Vitae
March 20161
Publication list
Harris LG,Murray S, Pascoe B,Bray JE,Méric G, MageirosL, WilkinsonTS,JeevesR,Rohde H,SchwarzS, de
Lencastre H, Miragaia M, RoloJ, BowdenR,Jolley KA,MaidenMCJ,Mack D, SheppardSK.Biofilmmorphotypes
and populationstructure among Staphylococcusepidermidis fromcommensalandclinical samples.PLoSOne
2016;11:e0151240
Al-IshaqR,ArmstrongJ,GregoryM, O'Hara M, Phiri K, Harris LG,Rohde H, SiemssenN,FrommeltL,Mack D,
WilkinsonTS.Effectsof polysaccharideintercellularadhesin(PIA)inanex vivomodel of whole bloodkillingandin
prostheticjointinfection(PJI):A role forC5a. IntJ Med Microbiol. 2015;305:948-56
Méric G, Miragaia M, de BeenM, Yahara K, Pascoe B, Mikhail J, Harris LG, Wilkinson TS, Rolo J, Lamble S, Bray JE,
Jolley KA, Hanage WP, Bowden R, Maiden MCJ, Mack D, de Lencastre H, Feil EJ, Corander J, Sheppard SK
Ecological overlap and horizontal gene transfer in Staphylococcus aureus and Staphylococcus epidermidis.
Genome Biol Evol. 2015;16;7:1313-28.
Pascoe B, Dams L, Wilkinson TS, Harris LG, Bodger O, Mack D, Davies AP (2014). Dormant cells of Staphylococcus
aureus are resuscitated by spent culture supernatant. PLoS One 2014;9:e8599.
Harris LG, Nigam Y, Sawyer J, Mack D, Pritchard DI. Lucilia sericata chymotrypsin disrupts protein adhesin-
mediated staphylococcal biofilm formation. Appl Environ Microbiol. 2013;79:1393-1395.
Mack D, Davies AP, Harris LG, Jeeves R, Pascoe B, Knobloch JKM, Rohde H, Wilkinson TS. Staphylococcus
epidermidis in biomaterial-associated infections (Book chapter). In Moriarty, T.F., Zaat, S.A.J. & Busscher, H.J.
(Eds.), Biomaterials Associated Infection (2013, Part 1, 25-56) Publisher: Springer New York, ISBN: 978-1-4614-
1031-7.
DaviesAP,ReidM, HadfieldSJ,JohnstonS,Mikhail J, HarrisLG, JenkinsonHF,BerryN,LewisAM, El-Bouri K, Mack
D. Identificationof clinical isolatesof α-hemolyticstreptococci by16S rRNA gene sequencing,matrix-assistedlaser
desorption ionization-time of flight mass spectrometry using MALDI biotyper, and conventional phenotypic
methods: a comparison. J Clin Microbiol. 2012;50:4087-90.
El-Bouri K,JohnstonS,ReesE, ThomasI, Bome-MannathokoN, Jones C, Reid M, Ben-Ismaeil B, Davies AP, Harris
LG, Mack D. Comparisonof bacterial identificationbyMALDI-TOFmassspectrometryandconventional diagnostic
microbiology methods: agreement, speed and cost implications. Br J Biomed Sci. 2012;69(2):47-55.
SpiliopoulouAI,KrevvataMI, Kolonitsiou F, Harris LG, Wilkinson TS, Davies AP, Dimitracopoulos GO, Karamanos
NK, Mack D, Anastassiou ED. An extracellular Staphylococcus epidermidis polysaccharide: relation to
Polysaccharide Intercellular Adhesin and its implication in phagocytosis. BMC Microbiol. 2012;12:76.
Harris LG, El-Bouri K,JohnstonS,ReesE, FrommeltL,SiemssenN,ChristnerM,DaviesAP,Rohde H,Mack D.
Rapididentificationof staphylococcifromprostheticjointinfectionsusingMALDI-TOFmass-spectrometry.IntJ
Artif Organs2010; 33: 568–574.
Jukes L, Mikhail J, Bome-Mannathoko N, Hadfield SJ, Harris LG, El-Bouri K, Davies AP, Mack D. Rapid
differentiationof Staphylococcusaureus, Staphylococcusepidermidis andothercoagulase negative staphylococci
and meticillinsusceptibilitytestingdirectlyfromgrowth-positive bloodculturesbymultiplex real-time PCR. J Med
Microbiol 2010; 59: 1456–1461.
Harris LG,Bexfield A,NigamY,Rohde H, Ratcliffe NA, Mack D. Disruption of Staphylococcus epidermidis biofilms
by medicinal maggot Lucilia sericata excretions/secretions. Int. J. Artif. Organs 2009; 32, 555-564.
Mack D, DaviesAP, Harris LG,KnoblochJKM,Rohde H. Staphylococcusepidermidis biofilms:functional molecules,
relation to virulence, and vaccine potential. Top. Curr. Chem. 2009; 288, 157-182.
Samek,O.,H. H. Telle, L.G. Harris, M. Bloomfield,andD.Mack. 2008. Raman spectroscopyforrapid
discriminationof Staphylococcusepidermidis clonesrelatedtomedical device-associatedinfections.
Laser Phys.Lett. 5:465-470.
HudetzD, HudetzSU, Harris LG,Luginbühl R,FriederichNF,LandmannR. Weak effect of metal type and ica gene
expression on staphylococcal infection of titanium and stainless steel implants. Clin Microbiol Infect.
2008;14:1135-1145.
Llinos GHarris - Curriculum Vitae
March 20162
Maddikeri RR, Tosatti S, Schuler M, Chessari S, Textor M, Richards RG, Harris LG (2008) Effect of modifying
titanium surfaces with PLL-g-PEG and RGD-functionalised PLL-g-PEG on bacterial adhesion. J Biomed Mat Res
84A:425–435.
Hübscher J, Jansen A, Kotte O, Schäfer J, Majcherczyk PA, Harris LG, Bierbaum G, Heinemann M, Berger-Bächi B
(2007) Living with an imperfect cell wall: Compensation of femAB inactivation in Staphylococcus aureus. BMC
Genomics 8:308.
Harris LG, MeredithDO,Eschbach L, RichardsRG (2007) Staphylococcusaureus adhesiontostandardmicro-rough
and electropolished implant materials. J Mat Sci Mat Med 18:1151-1156.
Rohde H, BurandtEC, SiemssenN,FrommeltL,Burdelski C,WursterS,Scherpe S,DaviesAP, Harris LG, Horstkotte
MA, Knobloch JKM, Kaplan JB, Mack D (2007) Differential importance of polysaccharide intercellular adhesin or
protein factors in biofilm accumulation of Staphylococcus epidermidis and Staphylococcus aureus isolated from
prosthetic hip and knee joint infections. Biomaterials 28: 1711-1720.
Mack D, Davies AP, Harris LG, Rohde H, Horstkotte MA, Knobloch JKM (2007) Microbial interactions in
Staphylococcus epidermidis biofilms. Anal Bioanal Chem 387:399-408.
Harris LG, Richards RG (2006) Staphylococci and implant surfaces: a review. Injury, 37:S3-14.
Mack D, Rohde H, Harris LG, Davies AP, Horstkotte MA, Knobloch JKM. (2006) Biofilm formation in medical
device-related infection Int J Artif Organs 29:343-359.
Harris LG,Mead L, Mueller-OberlanderE,RichardsRG (2006) Bacteriaand cell cytocompatibilitystudiesoncoated
medical grade titanium surfaces. J Biomed Mat Res 78A:50-58.
Seidl K, Stucki M, Ruegg M, Görke C, Wolz C, Harris LG, Berger-Bächi B, Bischoff M (2006) The Staphylococcus
aureus CcpA homologue affectsvirulence determinant production and antibiotic resistance. Antimicrob Agents
Chemother 50:1183-1194.
Harris LG,Gorna K, Gogolewski S,RichardsRG(2006) Biodegradable polyurethanecytocompatibilitytofibroblasts
and staphylococci. J Biomed Mat Res 77A:304–312.
Harris LG, Richards RG (2005). Implant coatings to prevent infection. AO Dialogue 18:23-24
Harris LG, Patterson LM, Bacon C, ap Gwynn I, Richards RG (2005). Assessment of the cytocompatibility of
different coated titanium surfaces to fibroblasts and osteoblasts. J Biomed Mat Res 73A:12-20.
ReinhartWH, PleischB, Harris LG,Lutolf M (2005). Influenceof contrastmedia(iopromide,ioxaglate,gadolinium-
DOTA) on bloodviscosity,erythrocyte morphologyandplateletfunction.ClinHemorheolMicrocirc32:227-239.
Harris LG,RichardsRG (2004). Staphylococcusaureus adhesiontodifferenttreatedtitaniumsurfaces. JMatSci
Mat Med 15:311-314.
Harris LG, Tosatti S, Richards RG, Textor M (2004). Staphylococcus aureus adhesion to titanium oxide surfaces
coatedwithnon-functionalizedandpeptide-functionalizedpoly(L-lysine)-graft-poly(ethylene glycol) copolymers.
Biomaterials, 25:4135-4148.
Harris LG, FosterSJ, RichardsRG (2002). An introductionto Staphylococcusaureus,andtechniquesforidentifying
and quantifying S. aureus adhesins in relation to adhesion to biomaterials: Review. Eur Cells Mat 4:39-60.
Clarke SJ, Harris LG, Richards RG, FosterSJ(2002). Analysisof Ebh,a 1.1 megaDaltonsurface, fibronectin binding
protein of Staphylococcus aureus. Infect Immun 70:6680-6687.
Bundy KJ, Harris LG, Rahn BA, Richards RG (2001). Measurement of fibroblast and bacterial detachment from
biomaterials using jet impingement. Cell Biol Int 25:1237-1249.
Mark M, Walter R, Harris LG, Reinhart WH (2000). Influence of parathyroid hormone, calcitonin, 1,25(OH)2
cholecalcifeol,calcium,andthe calciumionophore A23187 on erythrocyte morphology and blood viscosity. J Lab
Clin Med 135:347-352.
WalterR, Mark M, GaudenzR, Harris LG,ReinhartWH (1999). Influence of nitrovasodilators and endothelin-1 on
rheology of human blood in vitro. Br J Pharmacol 128:744-750.
Harris LG, ap Gwynn I, Richards RG (1999). Contrast optimisation for backscattered electron imaging of resin
embedded cells. Scan Micro 13:71-81.
Llinos GHarris - Curriculum Vitae
March 20163
Presentation list
Oral presentations
June 2015. Staphylococcus epidermidis, commensal to pathogenic? at ECMXVI, Davos, Switzerland.
June 2015. Populationgenomicsof Staphylococcusepidermidis,atthe ColegCymraegCenedlaethol 4th
Scientific
Conference,Aberystwyth,Wales,UK.
October2014. Medicinal maggot Lucilia sericata excretions/secretionsandtheireffectonbiofilms,at1st
iPROMEDAIworkshop,Porto,Portugal.
September 2014. Variation between implant associated and commensal Staphylococcus epidermidis, at 5th
Thesinge Biofilm meeting, Thesinge/Groningen, The Netherlands.
September 2013. Population genomics of Staphylococcus epidermidis, at Staph GBI 2013, Dublin, Ireland.
June 2011. Influence of biomaterials on Staphylococcus epidermidis biofilm formation, at ECMXII, Davos,
Switzerland.
July2010. Staphylococcusepidermidis biofilmdisruption by Lucilia sericata excretions/secretions, at the ENTO10
meeting in Swansea, UK.
November2009. Quorumsensing agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and
catheter infections, at Infection 2009, Birmingham, UK.
March 2009. Species identification in Staphylococcus using MALDI-ToF/MS, at SGMSpring meeting, Harrogate,
UK.
March 2009. Quorum sensing agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and
catheter infections, at SGMSpring meeting, Harrogate, UK.
September 2008. Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata
excretions/secretions, at the 13th International Symposium on Staphylococci and Staphylococcal Infections
(ISSSI), Cairns, Australia.
July 2008. Staphylococcus epidermidis biofilm disruption by medicinal maggot Lucilia sericata
excretions/secretions, at Staphylococcus GBI 2008, Leeds, UK.
Sept2006. Influence of biomaterialsonStaphylococcusbiofilm formation, at 12th
ISSSI, Maastricht, Netherlands.
April 2006. Biofilm formation of Staphylococcus epidermidis, at StaphGBI 2006, Liverpool, UK.
September 2005. Bacterial Reactions to Modified Biomaterial Surfaces, at Biosurf VI, Lausanne, Switzerland
(Invited speaker).
September2005. Staphylococci adhesiontocoatedtitanium surfaces impregnated with an antiseptic, at the 19th
European Conference on Biomaterials, Sorrento, Italy.
September 2005. Studying bacterial adhesion to biomaterials, at Microscopy 2005, Davos, Switzerland.
July 2005. Staphylococci and implants, at Medical School Seminar, Swansea University, Swansea, Wales, UK
(Invited speaker).
May 2005. Cytocompatibility of coated titanium surfaces impregnated with an antiseptic to staphylococci and
fibroblasts, at the 24th European Bone and Joint Infection Society, Ljubljana, Slovenia.
January 2005. Staphylococci and Implants, at the Institute of Medical Microbiology, University of Zurich, Zurich,
Switzerland (Invited speaker).
November2004. Staphylococcusaureus andmodifiedcoatedtitaniumimplants,atthe 14th
EuropeanOrthopaedic
Research Society, Amsterdam, the Netherlands.
October 2004. Bacterial Adhesion to Implantable Materials, at XIV Conference on Biomaterials in Medicine and
Veterinary medicine, Rytro, Poland.
June 2004. Analysingbacterial adhesiontobiomaterialsatthe EuropeanCellsandMaterialsV conference, Davos,
Switzerland (Invited speaker).
Llinos GHarris - Curriculum Vitae
March 20164
April 2004. The race for the surface: Bacteria and cell interaction with artificial materials, at Swiss Federal
Laboratory for material Testing and Research, EMPA, St Gallen, Switzerland (Invited speaker).
September 2003. Staphylococcus aureus adhesion to different treated titanium surfaces, at 18th
European
Conference on Biomaterials, Stuttgart, Germany.
May 2003. The effect of hydrophilicity of implantable biodegradable polyurethanes on cell and bacteria
cytocompatibility, at AO Research Institute, Davos, Switzerland.
November 2002. Molecular analysis of Staphylococcus aureus adhesins, at AO Research Institute, Davos,
Switzerland.
August 2002. Bacteria and Biomaterials, at ETH Zurich, Zurich, Switzerland (Invited speaker).
October 2001. Staphylococcus aureus surface protein topography, at Robert Mathys Foundation, Bettlach,
Switzerland.
June 2001. Staphylococcusaureus surface proteintopography,atthe EuropeanCellsand Materials II conference,
Davos, Switzerland (winner of the best presentation award).
Poster presentations
September2015. Harris LG,Pascoe B, Meric G, Murray S,MageriosL, Mack D, Schwarz S,de Lancastre H, Bowden
R, SheppardSK. Staphylococcusepidermidis,commensal topathogenic?at StaphGBI 2015, Reading,UK.
January2015. Harris LG,Pascoe B, Meric G, Murray S,MageriosL, Mack D, de Lancastre H, Schwarz S,BowdenR,
SheppardSK. Commensal topathogenic,how?,atMITReG annual meeting,Cardiff,UK.
December2013. Harris LG, Pascoe B, Rohde H, Mack D, SchwarzS, de Lancastre H, Miragaia M, RoloJ, BowdenR,
SheppardSK. Temporal variationinclinical coagulase negative staphylococci,atMITReG annual meeting,
Swansea,UK.
April 2013 Harris LG, Jeeves,R,Rohde H,Mack D, Sheppard SK. Staphylococcus epidermidis biofilm formation on
indwelling medical devices, at ECCMID 2013, Berlin, Germany.
March 2012. Harris LG, Jeeves, R, Rohde H, Mack D. Influence of biomaterials on Staphylococcus epidermidis
biofilm formation, at the SGMSpring meeting in Edinburgh, UK.
March 2012. Jeeves R, Harris LG, Mack D. Collagen Binding Factors in Clinical Isolates of Staphylococcus
epidermidis, at the SGMSpring meeting in Edinburgh, UK.
July2011. Harris LG, Jeeves,R,Rohde H,Mack D Influenceof biomaterialson Staphylococcus epidermidis biofilm
formation, at the Gordon Staphylococcus Diseases Conference, Braga, Italy.
September2010. Harris LG,DudleyE,Rohde H, Mack D. agr-specificitygroupsin Staphylococcusepidermidis from
prosthetic joint and catheter infections, at 14th
ISSSI, Bath, UK.
April 2010. SpiliopoulouAI, Krevvata MI, Kolonitsiou F, Harris LG, Wilkinson TS, Davies AP, Dimitracopoulos GO,
KaramanosNK,Mack D, AnastassiouED.Relationbetween20-kDapolysaccharide andPolysaccharide Intercellular
Adhesin of Staphylococcus epidermidis, at ECCMID 2010, Vienna, Austria.
November 2009. Bome-Mannathoko N, Wooton M, Harris LG, Howe R, Mack D. Molecular characterisation of
Panton-Valentine Leukocidin (PVL)-positive Staphylococcus aureus from Wales, at Infection 2009, Birmingham,
UK.
2009. JukesL,Mikhail J,HadfieldS, Harris LG, El-Bouri K,DaviesAP,Mack D. Rapid identification of staphylococci
and methicillinsusceptibility testing directly from growth positive blood cultures by real-time PCR, at Infection
2009, Birmingham, UK.
November2009. JonesC, Harris LG, ReesE, El-Bouri K, DaviesAP,Mack D. Molecularepidemiologyof extended-
spectrum β-lactamase (ESBL) carrying Enterobacteriaceae in Swansea, at Infection 2009, Birmingham, UK.
September 2009. Harris LG,, Dudley E, Rohde H, Mack D. agr-specificity groups in Staphylococcus epidermidis
from prosthetic joint and catheter infections, at Gordon Staphylococcus Diseases Conference, Waterville, NH.
USA.
Llinos GHarris - Curriculum Vitae
March 20165
September 2008. Harris LG, Bexfield A, Nigam Y, Rohde H, Ratcliffe NA, Mack D. Disruption of Staphylococcus
epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions, at 13th
ISSSI, Cairns, Australia.
July 2008. Bome-Mannathoko N, Harris LG, Hadfield S, Shepherd C, Johnston S, Rees E, El-Bouri K, Davies AP,
Mack D. Performance of SCCmec-orfX amplification and prevalence of Panton-Valentine Leukocidin (PVL) in
Staphylococcus aureus from wound and skin specimens, at Staphylococcus GBI 2008, Leeds, UK.
March 2007. Hübscher J, Jansen A, Kotte O, Schäfer J, Majcherczyk PA, Harris LG, Bierbaum G, Heinemann M,
Berger-Bächi B. Compensation of femAB deletion in Staphylococcus aureus: A strategy to survive with an
imperfect cell wall, at 160th
Society for General Microbiology meeting, Manchester, UK.
Sept 2006. Harris LG, Rohde H, Knobloch JKM & Mack D. Influence of biomaterials on Staphylococcus biofilm
formation, at 12th
ISSSI, Maastricht, Netherlands.
Sept2006. Maddikeri R,Tosatti S, RichardsRG & Harris LG. Bacterial adhesion to PLL-g-PEG modified surfaces, at
20th
European Conference on Biomaterials, Nantes, France.
Sept2005. Maddikeri R,Tosatti S, Richards RG & Harris LG. Bacterial adhesion to PLL-g-PEG modified Ti surfaces,
at Biosurf VI, Lausanne, Switzerland.
June 2005. Harris LG, Mead L, Mueller-OberlanderE& RichardsRG. Cytocompatibilityof coatedtitaniumsurfaces
impregnated with an antiseptic, at 11th General meeting of the Swiss Society for Biomaterials, Mägenwil,
Switzerland.
July2004. Harris LG, Gorna K,Gogolweski S& RichardsRG. Cytocompatibility of biodegradable polyurethanes to
cells and bacteria, at 10th General meeting of the Swiss Society for Biomaterials, Davos, Switzerland.
May 2004. Harris LG, Gorna K, Gogolweski S, & Richards RG. Cell and bacteria cytocompatibility on different
hydrophilic biodegradable polyurethanes, at 7th
World Biomaterials conference, Sydney, Australia.
September2003. Harris LG, Gorna K, Gogolweski S, & Richards RG. Effect of different hydrophilic polyurethanes
on cell and bacterial adhesion, at Biosurf V, Zurich, Switzerland.
May 2003. Harris LG, Tosatti S, Richards RG & Textor M. Staphylococcus aureus adhesion to different modified
titanium surfaces, at Interface Biology symposium, Rostock, Germany.
June 2003. PattersonL, Harris LG,ap GwynnI. & Richards RG. Fibroblastadhesion&morphology on titanium and
TAN withvarioussurface treatments, at 9th General meeting of the Swiss Society for Biomaterials, Neuachatel,
Switzerland.
June 2003. Bühler M, Harris LG, Zinger O, Landolt D & Richards RG. Characterisation of fibroblast adhesion on
titaniummodel surfaces,at9thGeneral meetingof the Swiss Society for Biomaterials, Neuachatel, Switzerland.
June 2003. Bacon C, Harris LG, ap GwynnI & RichardsRG. Osteoblastadhesion&morphologyand Staphylococcus
aureus on various coated orthopaedic implant surfaces, at 9th General meeting of the Swiss Society for
Biomaterials, Neuachatel, Switzerland.
September 2002. Harris LG, Tosatti S, Foster SJ, Richards RG & Textor M. Staphylococcus aureus adhesion to
biomaterials, at Society for General Microbiology conference, Loughborough, UK.
September 2001. Harris LG, Richards RG & Foster SJ. Staphylococcus aureus surface protein topography, at the
StaphUK conference, Leicester, UK.
August 2001. Clarke SR, Brummell K, McDowell P, Harris LG & Foster SJ, at the Gordon Staphylococcal Diseases
conference, Rhode Island, USA.
April 1998. Harris LG, ap Gwynn I & Richards RG. Contrast optimisation for backscattered electron imaging of
resinembeddedcells,atthe ScanningElectronMicroscopyconference,Universityof Wales,Aberystwyth, Wales,
UK.

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Publication list March 2016

  • 1. Llinos GHarris - Curriculum Vitae March 20161 Publication list Harris LG,Murray S, Pascoe B,Bray JE,Méric G, MageirosL, WilkinsonTS,JeevesR,Rohde H,SchwarzS, de Lencastre H, Miragaia M, RoloJ, BowdenR,Jolley KA,MaidenMCJ,Mack D, SheppardSK.Biofilmmorphotypes and populationstructure among Staphylococcusepidermidis fromcommensalandclinical samples.PLoSOne 2016;11:e0151240 Al-IshaqR,ArmstrongJ,GregoryM, O'Hara M, Phiri K, Harris LG,Rohde H, SiemssenN,FrommeltL,Mack D, WilkinsonTS.Effectsof polysaccharideintercellularadhesin(PIA)inanex vivomodel of whole bloodkillingandin prostheticjointinfection(PJI):A role forC5a. IntJ Med Microbiol. 2015;305:948-56 Méric G, Miragaia M, de BeenM, Yahara K, Pascoe B, Mikhail J, Harris LG, Wilkinson TS, Rolo J, Lamble S, Bray JE, Jolley KA, Hanage WP, Bowden R, Maiden MCJ, Mack D, de Lencastre H, Feil EJ, Corander J, Sheppard SK Ecological overlap and horizontal gene transfer in Staphylococcus aureus and Staphylococcus epidermidis. Genome Biol Evol. 2015;16;7:1313-28. Pascoe B, Dams L, Wilkinson TS, Harris LG, Bodger O, Mack D, Davies AP (2014). Dormant cells of Staphylococcus aureus are resuscitated by spent culture supernatant. PLoS One 2014;9:e8599. Harris LG, Nigam Y, Sawyer J, Mack D, Pritchard DI. Lucilia sericata chymotrypsin disrupts protein adhesin- mediated staphylococcal biofilm formation. Appl Environ Microbiol. 2013;79:1393-1395. Mack D, Davies AP, Harris LG, Jeeves R, Pascoe B, Knobloch JKM, Rohde H, Wilkinson TS. Staphylococcus epidermidis in biomaterial-associated infections (Book chapter). In Moriarty, T.F., Zaat, S.A.J. & Busscher, H.J. (Eds.), Biomaterials Associated Infection (2013, Part 1, 25-56) Publisher: Springer New York, ISBN: 978-1-4614- 1031-7. DaviesAP,ReidM, HadfieldSJ,JohnstonS,Mikhail J, HarrisLG, JenkinsonHF,BerryN,LewisAM, El-Bouri K, Mack D. Identificationof clinical isolatesof α-hemolyticstreptococci by16S rRNA gene sequencing,matrix-assistedlaser desorption ionization-time of flight mass spectrometry using MALDI biotyper, and conventional phenotypic methods: a comparison. J Clin Microbiol. 2012;50:4087-90. El-Bouri K,JohnstonS,ReesE, ThomasI, Bome-MannathokoN, Jones C, Reid M, Ben-Ismaeil B, Davies AP, Harris LG, Mack D. Comparisonof bacterial identificationbyMALDI-TOFmassspectrometryandconventional diagnostic microbiology methods: agreement, speed and cost implications. Br J Biomed Sci. 2012;69(2):47-55. SpiliopoulouAI,KrevvataMI, Kolonitsiou F, Harris LG, Wilkinson TS, Davies AP, Dimitracopoulos GO, Karamanos NK, Mack D, Anastassiou ED. An extracellular Staphylococcus epidermidis polysaccharide: relation to Polysaccharide Intercellular Adhesin and its implication in phagocytosis. BMC Microbiol. 2012;12:76. Harris LG, El-Bouri K,JohnstonS,ReesE, FrommeltL,SiemssenN,ChristnerM,DaviesAP,Rohde H,Mack D. Rapididentificationof staphylococcifromprostheticjointinfectionsusingMALDI-TOFmass-spectrometry.IntJ Artif Organs2010; 33: 568–574. Jukes L, Mikhail J, Bome-Mannathoko N, Hadfield SJ, Harris LG, El-Bouri K, Davies AP, Mack D. Rapid differentiationof Staphylococcusaureus, Staphylococcusepidermidis andothercoagulase negative staphylococci and meticillinsusceptibilitytestingdirectlyfromgrowth-positive bloodculturesbymultiplex real-time PCR. J Med Microbiol 2010; 59: 1456–1461. Harris LG,Bexfield A,NigamY,Rohde H, Ratcliffe NA, Mack D. Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions. Int. J. Artif. Organs 2009; 32, 555-564. Mack D, DaviesAP, Harris LG,KnoblochJKM,Rohde H. Staphylococcusepidermidis biofilms:functional molecules, relation to virulence, and vaccine potential. Top. Curr. Chem. 2009; 288, 157-182. Samek,O.,H. H. Telle, L.G. Harris, M. Bloomfield,andD.Mack. 2008. Raman spectroscopyforrapid discriminationof Staphylococcusepidermidis clonesrelatedtomedical device-associatedinfections. Laser Phys.Lett. 5:465-470. HudetzD, HudetzSU, Harris LG,Luginbühl R,FriederichNF,LandmannR. Weak effect of metal type and ica gene expression on staphylococcal infection of titanium and stainless steel implants. Clin Microbiol Infect. 2008;14:1135-1145.
  • 2. Llinos GHarris - Curriculum Vitae March 20162 Maddikeri RR, Tosatti S, Schuler M, Chessari S, Textor M, Richards RG, Harris LG (2008) Effect of modifying titanium surfaces with PLL-g-PEG and RGD-functionalised PLL-g-PEG on bacterial adhesion. J Biomed Mat Res 84A:425–435. Hübscher J, Jansen A, Kotte O, Schäfer J, Majcherczyk PA, Harris LG, Bierbaum G, Heinemann M, Berger-Bächi B (2007) Living with an imperfect cell wall: Compensation of femAB inactivation in Staphylococcus aureus. BMC Genomics 8:308. Harris LG, MeredithDO,Eschbach L, RichardsRG (2007) Staphylococcusaureus adhesiontostandardmicro-rough and electropolished implant materials. J Mat Sci Mat Med 18:1151-1156. Rohde H, BurandtEC, SiemssenN,FrommeltL,Burdelski C,WursterS,Scherpe S,DaviesAP, Harris LG, Horstkotte MA, Knobloch JKM, Kaplan JB, Mack D (2007) Differential importance of polysaccharide intercellular adhesin or protein factors in biofilm accumulation of Staphylococcus epidermidis and Staphylococcus aureus isolated from prosthetic hip and knee joint infections. Biomaterials 28: 1711-1720. Mack D, Davies AP, Harris LG, Rohde H, Horstkotte MA, Knobloch JKM (2007) Microbial interactions in Staphylococcus epidermidis biofilms. Anal Bioanal Chem 387:399-408. Harris LG, Richards RG (2006) Staphylococci and implant surfaces: a review. Injury, 37:S3-14. Mack D, Rohde H, Harris LG, Davies AP, Horstkotte MA, Knobloch JKM. (2006) Biofilm formation in medical device-related infection Int J Artif Organs 29:343-359. Harris LG,Mead L, Mueller-OberlanderE,RichardsRG (2006) Bacteriaand cell cytocompatibilitystudiesoncoated medical grade titanium surfaces. J Biomed Mat Res 78A:50-58. Seidl K, Stucki M, Ruegg M, Görke C, Wolz C, Harris LG, Berger-Bächi B, Bischoff M (2006) The Staphylococcus aureus CcpA homologue affectsvirulence determinant production and antibiotic resistance. Antimicrob Agents Chemother 50:1183-1194. Harris LG,Gorna K, Gogolewski S,RichardsRG(2006) Biodegradable polyurethanecytocompatibilitytofibroblasts and staphylococci. J Biomed Mat Res 77A:304–312. Harris LG, Richards RG (2005). Implant coatings to prevent infection. AO Dialogue 18:23-24 Harris LG, Patterson LM, Bacon C, ap Gwynn I, Richards RG (2005). Assessment of the cytocompatibility of different coated titanium surfaces to fibroblasts and osteoblasts. J Biomed Mat Res 73A:12-20. ReinhartWH, PleischB, Harris LG,Lutolf M (2005). Influenceof contrastmedia(iopromide,ioxaglate,gadolinium- DOTA) on bloodviscosity,erythrocyte morphologyandplateletfunction.ClinHemorheolMicrocirc32:227-239. Harris LG,RichardsRG (2004). Staphylococcusaureus adhesiontodifferenttreatedtitaniumsurfaces. JMatSci Mat Med 15:311-314. Harris LG, Tosatti S, Richards RG, Textor M (2004). Staphylococcus aureus adhesion to titanium oxide surfaces coatedwithnon-functionalizedandpeptide-functionalizedpoly(L-lysine)-graft-poly(ethylene glycol) copolymers. Biomaterials, 25:4135-4148. Harris LG, FosterSJ, RichardsRG (2002). An introductionto Staphylococcusaureus,andtechniquesforidentifying and quantifying S. aureus adhesins in relation to adhesion to biomaterials: Review. Eur Cells Mat 4:39-60. Clarke SJ, Harris LG, Richards RG, FosterSJ(2002). Analysisof Ebh,a 1.1 megaDaltonsurface, fibronectin binding protein of Staphylococcus aureus. Infect Immun 70:6680-6687. Bundy KJ, Harris LG, Rahn BA, Richards RG (2001). Measurement of fibroblast and bacterial detachment from biomaterials using jet impingement. Cell Biol Int 25:1237-1249. Mark M, Walter R, Harris LG, Reinhart WH (2000). Influence of parathyroid hormone, calcitonin, 1,25(OH)2 cholecalcifeol,calcium,andthe calciumionophore A23187 on erythrocyte morphology and blood viscosity. J Lab Clin Med 135:347-352. WalterR, Mark M, GaudenzR, Harris LG,ReinhartWH (1999). Influence of nitrovasodilators and endothelin-1 on rheology of human blood in vitro. Br J Pharmacol 128:744-750. Harris LG, ap Gwynn I, Richards RG (1999). Contrast optimisation for backscattered electron imaging of resin embedded cells. Scan Micro 13:71-81.
  • 3. Llinos GHarris - Curriculum Vitae March 20163 Presentation list Oral presentations June 2015. Staphylococcus epidermidis, commensal to pathogenic? at ECMXVI, Davos, Switzerland. June 2015. Populationgenomicsof Staphylococcusepidermidis,atthe ColegCymraegCenedlaethol 4th Scientific Conference,Aberystwyth,Wales,UK. October2014. Medicinal maggot Lucilia sericata excretions/secretionsandtheireffectonbiofilms,at1st iPROMEDAIworkshop,Porto,Portugal. September 2014. Variation between implant associated and commensal Staphylococcus epidermidis, at 5th Thesinge Biofilm meeting, Thesinge/Groningen, The Netherlands. September 2013. Population genomics of Staphylococcus epidermidis, at Staph GBI 2013, Dublin, Ireland. June 2011. Influence of biomaterials on Staphylococcus epidermidis biofilm formation, at ECMXII, Davos, Switzerland. July2010. Staphylococcusepidermidis biofilmdisruption by Lucilia sericata excretions/secretions, at the ENTO10 meeting in Swansea, UK. November2009. Quorumsensing agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and catheter infections, at Infection 2009, Birmingham, UK. March 2009. Species identification in Staphylococcus using MALDI-ToF/MS, at SGMSpring meeting, Harrogate, UK. March 2009. Quorum sensing agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and catheter infections, at SGMSpring meeting, Harrogate, UK. September 2008. Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions, at the 13th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI), Cairns, Australia. July 2008. Staphylococcus epidermidis biofilm disruption by medicinal maggot Lucilia sericata excretions/secretions, at Staphylococcus GBI 2008, Leeds, UK. Sept2006. Influence of biomaterialsonStaphylococcusbiofilm formation, at 12th ISSSI, Maastricht, Netherlands. April 2006. Biofilm formation of Staphylococcus epidermidis, at StaphGBI 2006, Liverpool, UK. September 2005. Bacterial Reactions to Modified Biomaterial Surfaces, at Biosurf VI, Lausanne, Switzerland (Invited speaker). September2005. Staphylococci adhesiontocoatedtitanium surfaces impregnated with an antiseptic, at the 19th European Conference on Biomaterials, Sorrento, Italy. September 2005. Studying bacterial adhesion to biomaterials, at Microscopy 2005, Davos, Switzerland. July 2005. Staphylococci and implants, at Medical School Seminar, Swansea University, Swansea, Wales, UK (Invited speaker). May 2005. Cytocompatibility of coated titanium surfaces impregnated with an antiseptic to staphylococci and fibroblasts, at the 24th European Bone and Joint Infection Society, Ljubljana, Slovenia. January 2005. Staphylococci and Implants, at the Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland (Invited speaker). November2004. Staphylococcusaureus andmodifiedcoatedtitaniumimplants,atthe 14th EuropeanOrthopaedic Research Society, Amsterdam, the Netherlands. October 2004. Bacterial Adhesion to Implantable Materials, at XIV Conference on Biomaterials in Medicine and Veterinary medicine, Rytro, Poland. June 2004. Analysingbacterial adhesiontobiomaterialsatthe EuropeanCellsandMaterialsV conference, Davos, Switzerland (Invited speaker).
  • 4. Llinos GHarris - Curriculum Vitae March 20164 April 2004. The race for the surface: Bacteria and cell interaction with artificial materials, at Swiss Federal Laboratory for material Testing and Research, EMPA, St Gallen, Switzerland (Invited speaker). September 2003. Staphylococcus aureus adhesion to different treated titanium surfaces, at 18th European Conference on Biomaterials, Stuttgart, Germany. May 2003. The effect of hydrophilicity of implantable biodegradable polyurethanes on cell and bacteria cytocompatibility, at AO Research Institute, Davos, Switzerland. November 2002. Molecular analysis of Staphylococcus aureus adhesins, at AO Research Institute, Davos, Switzerland. August 2002. Bacteria and Biomaterials, at ETH Zurich, Zurich, Switzerland (Invited speaker). October 2001. Staphylococcus aureus surface protein topography, at Robert Mathys Foundation, Bettlach, Switzerland. June 2001. Staphylococcusaureus surface proteintopography,atthe EuropeanCellsand Materials II conference, Davos, Switzerland (winner of the best presentation award). Poster presentations September2015. Harris LG,Pascoe B, Meric G, Murray S,MageriosL, Mack D, Schwarz S,de Lancastre H, Bowden R, SheppardSK. Staphylococcusepidermidis,commensal topathogenic?at StaphGBI 2015, Reading,UK. January2015. Harris LG,Pascoe B, Meric G, Murray S,MageriosL, Mack D, de Lancastre H, Schwarz S,BowdenR, SheppardSK. Commensal topathogenic,how?,atMITReG annual meeting,Cardiff,UK. December2013. Harris LG, Pascoe B, Rohde H, Mack D, SchwarzS, de Lancastre H, Miragaia M, RoloJ, BowdenR, SheppardSK. Temporal variationinclinical coagulase negative staphylococci,atMITReG annual meeting, Swansea,UK. April 2013 Harris LG, Jeeves,R,Rohde H,Mack D, Sheppard SK. Staphylococcus epidermidis biofilm formation on indwelling medical devices, at ECCMID 2013, Berlin, Germany. March 2012. Harris LG, Jeeves, R, Rohde H, Mack D. Influence of biomaterials on Staphylococcus epidermidis biofilm formation, at the SGMSpring meeting in Edinburgh, UK. March 2012. Jeeves R, Harris LG, Mack D. Collagen Binding Factors in Clinical Isolates of Staphylococcus epidermidis, at the SGMSpring meeting in Edinburgh, UK. July2011. Harris LG, Jeeves,R,Rohde H,Mack D Influenceof biomaterialson Staphylococcus epidermidis biofilm formation, at the Gordon Staphylococcus Diseases Conference, Braga, Italy. September2010. Harris LG,DudleyE,Rohde H, Mack D. agr-specificitygroupsin Staphylococcusepidermidis from prosthetic joint and catheter infections, at 14th ISSSI, Bath, UK. April 2010. SpiliopoulouAI, Krevvata MI, Kolonitsiou F, Harris LG, Wilkinson TS, Davies AP, Dimitracopoulos GO, KaramanosNK,Mack D, AnastassiouED.Relationbetween20-kDapolysaccharide andPolysaccharide Intercellular Adhesin of Staphylococcus epidermidis, at ECCMID 2010, Vienna, Austria. November 2009. Bome-Mannathoko N, Wooton M, Harris LG, Howe R, Mack D. Molecular characterisation of Panton-Valentine Leukocidin (PVL)-positive Staphylococcus aureus from Wales, at Infection 2009, Birmingham, UK. 2009. JukesL,Mikhail J,HadfieldS, Harris LG, El-Bouri K,DaviesAP,Mack D. Rapid identification of staphylococci and methicillinsusceptibility testing directly from growth positive blood cultures by real-time PCR, at Infection 2009, Birmingham, UK. November2009. JonesC, Harris LG, ReesE, El-Bouri K, DaviesAP,Mack D. Molecularepidemiologyof extended- spectrum β-lactamase (ESBL) carrying Enterobacteriaceae in Swansea, at Infection 2009, Birmingham, UK. September 2009. Harris LG,, Dudley E, Rohde H, Mack D. agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and catheter infections, at Gordon Staphylococcus Diseases Conference, Waterville, NH. USA.
  • 5. Llinos GHarris - Curriculum Vitae March 20165 September 2008. Harris LG, Bexfield A, Nigam Y, Rohde H, Ratcliffe NA, Mack D. Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions, at 13th ISSSI, Cairns, Australia. July 2008. Bome-Mannathoko N, Harris LG, Hadfield S, Shepherd C, Johnston S, Rees E, El-Bouri K, Davies AP, Mack D. Performance of SCCmec-orfX amplification and prevalence of Panton-Valentine Leukocidin (PVL) in Staphylococcus aureus from wound and skin specimens, at Staphylococcus GBI 2008, Leeds, UK. March 2007. Hübscher J, Jansen A, Kotte O, Schäfer J, Majcherczyk PA, Harris LG, Bierbaum G, Heinemann M, Berger-Bächi B. Compensation of femAB deletion in Staphylococcus aureus: A strategy to survive with an imperfect cell wall, at 160th Society for General Microbiology meeting, Manchester, UK. Sept 2006. Harris LG, Rohde H, Knobloch JKM & Mack D. Influence of biomaterials on Staphylococcus biofilm formation, at 12th ISSSI, Maastricht, Netherlands. Sept2006. Maddikeri R,Tosatti S, RichardsRG & Harris LG. Bacterial adhesion to PLL-g-PEG modified surfaces, at 20th European Conference on Biomaterials, Nantes, France. Sept2005. Maddikeri R,Tosatti S, Richards RG & Harris LG. Bacterial adhesion to PLL-g-PEG modified Ti surfaces, at Biosurf VI, Lausanne, Switzerland. June 2005. Harris LG, Mead L, Mueller-OberlanderE& RichardsRG. Cytocompatibilityof coatedtitaniumsurfaces impregnated with an antiseptic, at 11th General meeting of the Swiss Society for Biomaterials, Mägenwil, Switzerland. July2004. Harris LG, Gorna K,Gogolweski S& RichardsRG. Cytocompatibility of biodegradable polyurethanes to cells and bacteria, at 10th General meeting of the Swiss Society for Biomaterials, Davos, Switzerland. May 2004. Harris LG, Gorna K, Gogolweski S, & Richards RG. Cell and bacteria cytocompatibility on different hydrophilic biodegradable polyurethanes, at 7th World Biomaterials conference, Sydney, Australia. September2003. Harris LG, Gorna K, Gogolweski S, & Richards RG. Effect of different hydrophilic polyurethanes on cell and bacterial adhesion, at Biosurf V, Zurich, Switzerland. May 2003. Harris LG, Tosatti S, Richards RG & Textor M. Staphylococcus aureus adhesion to different modified titanium surfaces, at Interface Biology symposium, Rostock, Germany. June 2003. PattersonL, Harris LG,ap GwynnI. & Richards RG. Fibroblastadhesion&morphology on titanium and TAN withvarioussurface treatments, at 9th General meeting of the Swiss Society for Biomaterials, Neuachatel, Switzerland. June 2003. Bühler M, Harris LG, Zinger O, Landolt D & Richards RG. Characterisation of fibroblast adhesion on titaniummodel surfaces,at9thGeneral meetingof the Swiss Society for Biomaterials, Neuachatel, Switzerland. June 2003. Bacon C, Harris LG, ap GwynnI & RichardsRG. Osteoblastadhesion&morphologyand Staphylococcus aureus on various coated orthopaedic implant surfaces, at 9th General meeting of the Swiss Society for Biomaterials, Neuachatel, Switzerland. September 2002. Harris LG, Tosatti S, Foster SJ, Richards RG & Textor M. Staphylococcus aureus adhesion to biomaterials, at Society for General Microbiology conference, Loughborough, UK. September 2001. Harris LG, Richards RG & Foster SJ. Staphylococcus aureus surface protein topography, at the StaphUK conference, Leicester, UK. August 2001. Clarke SR, Brummell K, McDowell P, Harris LG & Foster SJ, at the Gordon Staphylococcal Diseases conference, Rhode Island, USA. April 1998. Harris LG, ap Gwynn I & Richards RG. Contrast optimisation for backscattered electron imaging of resinembeddedcells,atthe ScanningElectronMicroscopyconference,Universityof Wales,Aberystwyth, Wales, UK.