This document is a curriculum vitae for Llinos GHarris that includes a publication list and presentation list from March 2016. The publication list details 18 publications from 2016 to 1999 where Harris is listed as an author, focusing on topics related to Staphylococcus biofilms and identification. The presentation list outlines 18 oral presentations given by Harris from 2015 to 2002 on similar topics regarding Staphylococcus species and their interaction with biomaterials and biofilms.
This document provides references to 42 scientific papers related to viruses and vaccines. Many of the papers discuss research on orthopoxviruses like vaccinia virus and variola virus (which causes smallpox), as well as other viruses. The papers investigate topics like viral replication, inhibition of viruses, immune responses to vaccines, and evaluation of vaccine candidates. Many of the authors are affiliated with the Institut Pasteur.
Vitamin D deficiency is a modifiable risk factor for periprosthetic joint infection (PJI).
A mouse study found that vitamin D deficient mice had higher bacterial burdens and colony forming units on implants and tissues compared to vitamin D sufficient mice. Mice "rescued" from deficiency with a perioperative vitamin D bolus had similar low infection rates as sufficient mice.
A human study aims to determine if biomarkers and transcriptomics can predict innate immune response outcomes from perioperative vitamin D supplementation, with the goal of decreasing PJI rates through inexpensive vitamin D priming of the immune system prior to surgery. The mouse model provides a platform to test clinical aims around optimizing vitamin D dosing to reduce PJI
This study analyzed bed bugs collected over one year from a lower-income apartment building with recurring infestations after heat treatments. Genetic analysis found that 73% of infestations were from the same lineages, indicating heat treatments were ineffective at eliminating populations. Up to 5 infestations represented new introductions. High levels of pyrethroid resistance were also found. The researchers concluded ineffective heat treatments, new introductions, reintroductions, local spread, and high pyrethroid resistance caused chronic infestations.
This document provides the curriculum vitae of Khaled Mahmood Al-Qaoud, including his education, professional experience, patents, and publications. It lists that he received a PhD in Immunology from Hamburg University in Germany, worked as a professor of Immunology at Yarmouk University in Jordan, and has authored over 30 scientific publications in peer-reviewed journals. It also outlines his roles managing research and production for a monoclonal antibody company from 2010-2015 and serving as chairman of the Department of Biological Sciences at Yarmouk University.
Ligand and structure based drug design against antimicrobial resistance induc...Mohit Kumar
Helicobacter pylori is a gram-negative, microaerophilic bacterium found usually in the stomach of a person with chronic gastritis and gastric ulcers. More than 50% of the world’s population harbor H. pylori in their upper gastrointestinal tract. About 85% of people infected with H. pylori never experience symptoms or complications. Individuals with chronic gastritis and infected with H. pylori have a 10 to 20% lifetime risk of developing peptic ulcers, MALT lymphoma, the pathogenesis of gastric cancer and several extra-gastric diseases. No vaccines are developed yet and the bacterial antibiotic resistance has been a growing concern. Helicobacter pylori produce virulence and antibiotic resistance through quorum sensing mechanisms by generating AI-2. Inhibition of quorum sensing would be a novel approach for the effective treatment of antibiotic-resistant strains of H. pylori. Chemical nature of AI-2 is furanosyl borate diester which is generated from 4,5-dihydroxy 2,3-pentanedione (DPD). But there are no synthetic congeners of AI-2 and DPD compounds tested against H. pylori till date. Therefore, it is the aim of the present study to design some potent AI-2 and DPD compounds under the framework of pharmacophore modeling.
Non-Invasive Methods for Biomonitoring Trace Element ExposureChris Harrington
Finger and toe nails don't seem very interesting at the best of times, but did you know they carry a record of your exposure to metals like lead and arsenic?
In this presentation I review how these materials can show if people are being exposed to trace metals and how they can be used to link exposure to possible early health effects.
The talk includes work from 3 PhD projects that I have been involved in and show how a project can develop from a humble beginning to cutting edge research.
Kimberly Carter evaluated the efficacy of multivalent virus-like particle (VLP) antigens in enzyme-linked immunosorbent assays (ELISAs) for detecting antibodies against infectious bursal disease virus (IBDV) strains. Multivalent VLPs containing VP3, a classic strain pVP2, and a variant strain pVP2 were produced. ELISAs using these antigens yielded positive results at low serum dilutions but not higher dilutions. Antigens containing a single VP3 and pVP2 appeared more effective. While multivalent VLP ELISAs showed some ability to detect antibodies, commercial ELISA kits still need testing for superior performance.
Methicillin Resistant Staphylococcus aureus (MRSA) is a bacterium that is resistant to many antibiotics and causes difficult-to-treat infections. MRSA was first identified in the 1960s after methicillin was introduced. It has since spread worldwide and is a major public health concern. MRSA infections present with symptoms like skin abscesses or boils and can become life-threatening. Diagnosis involves culturing samples from infected sites and testing bacterial growth with antibiotics. Treatment options are limited since MRSA is resistant to many drugs.
This document provides references to 42 scientific papers related to viruses and vaccines. Many of the papers discuss research on orthopoxviruses like vaccinia virus and variola virus (which causes smallpox), as well as other viruses. The papers investigate topics like viral replication, inhibition of viruses, immune responses to vaccines, and evaluation of vaccine candidates. Many of the authors are affiliated with the Institut Pasteur.
Vitamin D deficiency is a modifiable risk factor for periprosthetic joint infection (PJI).
A mouse study found that vitamin D deficient mice had higher bacterial burdens and colony forming units on implants and tissues compared to vitamin D sufficient mice. Mice "rescued" from deficiency with a perioperative vitamin D bolus had similar low infection rates as sufficient mice.
A human study aims to determine if biomarkers and transcriptomics can predict innate immune response outcomes from perioperative vitamin D supplementation, with the goal of decreasing PJI rates through inexpensive vitamin D priming of the immune system prior to surgery. The mouse model provides a platform to test clinical aims around optimizing vitamin D dosing to reduce PJI
This study analyzed bed bugs collected over one year from a lower-income apartment building with recurring infestations after heat treatments. Genetic analysis found that 73% of infestations were from the same lineages, indicating heat treatments were ineffective at eliminating populations. Up to 5 infestations represented new introductions. High levels of pyrethroid resistance were also found. The researchers concluded ineffective heat treatments, new introductions, reintroductions, local spread, and high pyrethroid resistance caused chronic infestations.
This document provides the curriculum vitae of Khaled Mahmood Al-Qaoud, including his education, professional experience, patents, and publications. It lists that he received a PhD in Immunology from Hamburg University in Germany, worked as a professor of Immunology at Yarmouk University in Jordan, and has authored over 30 scientific publications in peer-reviewed journals. It also outlines his roles managing research and production for a monoclonal antibody company from 2010-2015 and serving as chairman of the Department of Biological Sciences at Yarmouk University.
Ligand and structure based drug design against antimicrobial resistance induc...Mohit Kumar
Helicobacter pylori is a gram-negative, microaerophilic bacterium found usually in the stomach of a person with chronic gastritis and gastric ulcers. More than 50% of the world’s population harbor H. pylori in their upper gastrointestinal tract. About 85% of people infected with H. pylori never experience symptoms or complications. Individuals with chronic gastritis and infected with H. pylori have a 10 to 20% lifetime risk of developing peptic ulcers, MALT lymphoma, the pathogenesis of gastric cancer and several extra-gastric diseases. No vaccines are developed yet and the bacterial antibiotic resistance has been a growing concern. Helicobacter pylori produce virulence and antibiotic resistance through quorum sensing mechanisms by generating AI-2. Inhibition of quorum sensing would be a novel approach for the effective treatment of antibiotic-resistant strains of H. pylori. Chemical nature of AI-2 is furanosyl borate diester which is generated from 4,5-dihydroxy 2,3-pentanedione (DPD). But there are no synthetic congeners of AI-2 and DPD compounds tested against H. pylori till date. Therefore, it is the aim of the present study to design some potent AI-2 and DPD compounds under the framework of pharmacophore modeling.
Non-Invasive Methods for Biomonitoring Trace Element ExposureChris Harrington
Finger and toe nails don't seem very interesting at the best of times, but did you know they carry a record of your exposure to metals like lead and arsenic?
In this presentation I review how these materials can show if people are being exposed to trace metals and how they can be used to link exposure to possible early health effects.
The talk includes work from 3 PhD projects that I have been involved in and show how a project can develop from a humble beginning to cutting edge research.
Kimberly Carter evaluated the efficacy of multivalent virus-like particle (VLP) antigens in enzyme-linked immunosorbent assays (ELISAs) for detecting antibodies against infectious bursal disease virus (IBDV) strains. Multivalent VLPs containing VP3, a classic strain pVP2, and a variant strain pVP2 were produced. ELISAs using these antigens yielded positive results at low serum dilutions but not higher dilutions. Antigens containing a single VP3 and pVP2 appeared more effective. While multivalent VLP ELISAs showed some ability to detect antibodies, commercial ELISA kits still need testing for superior performance.
Methicillin Resistant Staphylococcus aureus (MRSA) is a bacterium that is resistant to many antibiotics and causes difficult-to-treat infections. MRSA was first identified in the 1960s after methicillin was introduced. It has since spread worldwide and is a major public health concern. MRSA infections present with symptoms like skin abscesses or boils and can become life-threatening. Diagnosis involves culturing samples from infected sites and testing bacterial growth with antibiotics. Treatment options are limited since MRSA is resistant to many drugs.
Cytoplasmic male-sterility influences the expression of resistance to insects...ICRISAT
This study investigated how cytoplasmic male sterility (CMS) influences insect resistance in sorghum. Twelve male-sterile lines and their maintainer lines were evaluated for resistance to two insects, while 35 lines were evaluated for resistance to a third insect and four lines for resistance to a fourth insect. The results showed that male-sterile lines were generally more susceptible to insects than their maintainer counterparts. Resistance in both the male-sterile and maintainer parent was needed to produce insect-resistant hybrids. The female, male-sterile parent had a greater influence on the level of insect resistance or susceptibility expressed in the hybrid. These findings are important for developing and deploying insect-resistant sorghum hybrids for
Phenotypic and Biotypic Characterization of Klebsiella oxytoca: An Impact of ...albertdivis
Klebsiella oxytoca (K. oxytoca) is a Gram-negative microbe generally associated with community and hospitalacquired infections. Due to its clinical significance, we evaluated the effect of biofield treatment on phenotype and biotype characteristics of K. oxytoca (ATCC 43165).
This document lists 39 peer-reviewed research papers published by Dr. Kevin Gorman. The papers cover topics including field-evolved resistance to various insecticides in pests such as the brown planthopper and greenhouse whitefly, cross-resistance relationships between insecticides, identification of mutations associated with pyrethroid resistance, and characterization of resistance to neonicotinoid insecticides in species like Bemisia tabaci. Many of the papers involve characterizing the mechanisms and genetics of insecticide resistance.
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild ...Guy Boulianne
This study systematically mapped SARS-CoV-2-specific T cell responses in various groups including unexposed individuals, exposed family members, and those with acute or convalescent COVID-19. They found that:
1) Acute-phase SARS-CoV-2-specific T cells displayed an activated cytotoxic phenotype correlated with disease severity.
2) Convalescent-phase SARS-CoV-2-specific T cells were polyfunctional and displayed a stem-like memory phenotype.
3) Importantly, SARS-CoV-2-specific T cells were detectable in seronegative exposed family members and those with asymptomatic/mild COVID-19, suggesting natural exposure may prevent severe COVID-19 upon
Presentation from the 2014 Waterloo iGEM team at the Giant Jamboree in Boston. Read more about Staphylocide, our microbe engineered to silence antiobiotic resistance, on our 2014 wiki: http://2014.igem.org/Team:Waterloo.
This presentation is also available on the iGEM website: http://2014.igem.org/files/presentation/Waterloo_Championship.pdf
Phagebiotics: A New Horizon for Therapeutics in Aquacultureidrish123
The document discusses the use of bacteriophages (phages) as a treatment for bacterial infections in aquaculture. Phages are viruses that infect and replicate within bacteria. They have a lytic life cycle where they destroy the bacterial host. Phages are highly specific, only infecting certain bacterial strains, and do not harm normal microbiota. The document outlines strategies for developing phage therapies, including isolation, characterization, and testing of phages. It discusses methods of application in aquaculture like oral administration and immersion. Several examples of successful uses of phages to treat bacterial diseases in aquaculture species are provided. Advantages like specificity and ease of propagation are discussed, as well as limitations such as bacterial
Timothy W Morris - Publications & PresentationsTimothy Morris
This document provides a list of 37 publications by Timothy W. Morris, Ph.D. dating from 1999 to 2015. The publications focus on research related to ophthalmic pathogens, antibiotic resistance, and new antibiotics. Key areas investigated include the effects of contact lens solutions on Acanthamoeba encystment, surveillance of antibiotic resistance in ocular microorganisms, clinical trials of besifloxacin to treat bacterial conjunctivitis, and molecular mechanisms of antibiotic resistance in pathogens like Staphylococcus aureus.
EWMA 2013 - Ep451 An in vitro and clinical assessment of a nonadherent, antim...EWMAConference
Sharon Lindsay, Alexander Waite, Rachael McInnes, Breda Cullen, Systagenix, Gargrave, UK
Robert J. Snyder, DPM, MSc, CWS, Professor, Barry University SPM, Miami Shores, Florida, USA
1) Laboratory tests found that bacteria died within hours of contact with copper alloy surfaces, with over 99.9% reduction in live bacteria.
2) A clinical trial found an 83% reduction in bacteria levels on copper alloy surfaces in hospital rooms compared to standard materials. Infection rates were 58% lower in rooms with copper components.
3) The article concludes that copper alloys have potential to reduce hospital-acquired infections and costs by continuously killing bacteria without human intervention.
Genetic engineering is the best technology that is promoting the world and this technology is applied to many plants, animals and microorganisms. It has wider applications in the field of Biology, Medicine, Industry, Research, Agriculture and many other fields of science. In this research paper I update the Roles of Genetic Engineering in Agriculture, Animals, Human enhancement and Evolution, Bacteriophage Against Infectious Diseases, Medicines, Phage in Infectious Diseases, Biofuels Production and Improve Plant Performance Under Drought.
Genetic Resistance to Infectious Diseases in the Era of Personalized Medicine...CrimsonpublishersCJMI
Genetic Resistance to Infectious Diseases in the Era of Personalized Medicine by Andrei Alimov in Cohesive Journal of Microbiology & Infectious Disease
This document describes the development of a multiplex PCR assay targeting the cgcA gene, which encodes a diguanylate cyclase, to differentiate between species within the genus Cronobacter. Analysis of 12 Cronobacter genomes identified 7 conserved diguanylate cyclase-encoding genes, one of which, cgcA, showed species-specific divergence that matched known phylogenetic relationships between Cronobacter species. Primers were designed for this gene and tested in a multiplex PCR assay on 305 Cronobacter isolates representing 6 species. The assay correctly identified the species of all isolates tested and did not identify any of 20 non-Cronobacter species, demonstrating high specificity and sensitivity for rapid identification of Cronobacter.
This document discusses antimicrobial resistance mechanisms in Staphylococcus aureus, specifically methicillin-resistant S. aureus (MRSA). MRSA infections are now responsible for more deaths per year in the US than HIV and add billions to healthcare costs worldwide. MRSA strains have developed diverse genetic elements that confer resistance to multiple antimicrobials like methicillin, aminoglycosides, erythromycin, and tetracycline. Certain MRSA strains are also resistant to additional drugs including fluoroquinolones. Effective antimicrobial therapy is threatened as S. aureus continues developing resistance.
SIV Viral Variation; Implications for Vaccines and Transmission - Mars Stone PhDMars Stone
SIV Viral Variation; Implications for Vaccines and Transmission
PART 1 Viral diversity at mucosal transmission
-determine if vaginal SIV inoculation of rhesus macaques
recapitulates HIV-1 variant transmission
PART 2 Viral diversity in vaccine setting
-Characterize the replication levels and anatomic distribution of vaccine (SHIV 89.6) and challenge (SIVmac239) virus in monkeys prior to and after challenge.
-Characterize evolution of SIV env population complexity of SIV DNA in PBMC of SHIV immunized and control animals
Sarah Fox-Greer is seeking an industrial scientist position where she can apply her strong expertise in pharmacology, inflammation biology, and immunology gained over a decade of lab experience. She has a Ph.D. in cation exchanged zeolites as storage materials for nitric oxide and their therapeutic potential, and has extensive experience isolating and culturing various cells, performing assays and techniques such as flow cytometry and confocal imaging. Her research has focused on investigating pathways involved in apoptotic cell clearance and the progression of inflammation, and the potential of CDK inhibitor drugs as anti-inflammatory therapeutics. She has mentored students and published multiple papers in peer-reviewed journals.
This document summarizes different levels of host susceptibility that can contribute to dysbiosis. At the microbial level, controlled inflammation allows commensals to coexist while pathogens subvert the immune response. At the host tissue level, the response to biofilm formation and genetic and immunological factors determine susceptibility. At the systemic level, periodontal bacteria and their toxins can enter the bloodstream and contribute to inflammation in distant sites, while reduced oxygen pressure allows pathogens to thrive. The key points are that the host drives pathogen variation and it is unclear if periodontitis should be resolved through treating the infection or inflammation.
1. The document lists 29 publications with the author Lu Y, demonstrating their expertise in biomedical research related to neurodegenerative diseases and therapeutic antibody development.
2. Many of the publications focus on characterizing antibody delivery across the blood-brain barrier and targeting proteins involved in diseases like Alzheimer's.
3. The publications span from 2004 to the present and represent collaborative work with numerous co-authors investigating topics like antibody pharmacokinetics and biomarkers.
Cytoplasmic male-sterility influences the expression of resistance to insects...ICRISAT
This study investigated how cytoplasmic male sterility (CMS) influences insect resistance in sorghum. Twelve male-sterile lines and their maintainer lines were evaluated for resistance to two insects, while 35 lines were evaluated for resistance to a third insect and four lines for resistance to a fourth insect. The results showed that male-sterile lines were generally more susceptible to insects than their maintainer counterparts. Resistance in both the male-sterile and maintainer parent was needed to produce insect-resistant hybrids. The female, male-sterile parent had a greater influence on the level of insect resistance or susceptibility expressed in the hybrid. These findings are important for developing and deploying insect-resistant sorghum hybrids for
Phenotypic and Biotypic Characterization of Klebsiella oxytoca: An Impact of ...albertdivis
Klebsiella oxytoca (K. oxytoca) is a Gram-negative microbe generally associated with community and hospitalacquired infections. Due to its clinical significance, we evaluated the effect of biofield treatment on phenotype and biotype characteristics of K. oxytoca (ATCC 43165).
This document lists 39 peer-reviewed research papers published by Dr. Kevin Gorman. The papers cover topics including field-evolved resistance to various insecticides in pests such as the brown planthopper and greenhouse whitefly, cross-resistance relationships between insecticides, identification of mutations associated with pyrethroid resistance, and characterization of resistance to neonicotinoid insecticides in species like Bemisia tabaci. Many of the papers involve characterizing the mechanisms and genetics of insecticide resistance.
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild ...Guy Boulianne
This study systematically mapped SARS-CoV-2-specific T cell responses in various groups including unexposed individuals, exposed family members, and those with acute or convalescent COVID-19. They found that:
1) Acute-phase SARS-CoV-2-specific T cells displayed an activated cytotoxic phenotype correlated with disease severity.
2) Convalescent-phase SARS-CoV-2-specific T cells were polyfunctional and displayed a stem-like memory phenotype.
3) Importantly, SARS-CoV-2-specific T cells were detectable in seronegative exposed family members and those with asymptomatic/mild COVID-19, suggesting natural exposure may prevent severe COVID-19 upon
Presentation from the 2014 Waterloo iGEM team at the Giant Jamboree in Boston. Read more about Staphylocide, our microbe engineered to silence antiobiotic resistance, on our 2014 wiki: http://2014.igem.org/Team:Waterloo.
This presentation is also available on the iGEM website: http://2014.igem.org/files/presentation/Waterloo_Championship.pdf
Phagebiotics: A New Horizon for Therapeutics in Aquacultureidrish123
The document discusses the use of bacteriophages (phages) as a treatment for bacterial infections in aquaculture. Phages are viruses that infect and replicate within bacteria. They have a lytic life cycle where they destroy the bacterial host. Phages are highly specific, only infecting certain bacterial strains, and do not harm normal microbiota. The document outlines strategies for developing phage therapies, including isolation, characterization, and testing of phages. It discusses methods of application in aquaculture like oral administration and immersion. Several examples of successful uses of phages to treat bacterial diseases in aquaculture species are provided. Advantages like specificity and ease of propagation are discussed, as well as limitations such as bacterial
Timothy W Morris - Publications & PresentationsTimothy Morris
This document provides a list of 37 publications by Timothy W. Morris, Ph.D. dating from 1999 to 2015. The publications focus on research related to ophthalmic pathogens, antibiotic resistance, and new antibiotics. Key areas investigated include the effects of contact lens solutions on Acanthamoeba encystment, surveillance of antibiotic resistance in ocular microorganisms, clinical trials of besifloxacin to treat bacterial conjunctivitis, and molecular mechanisms of antibiotic resistance in pathogens like Staphylococcus aureus.
EWMA 2013 - Ep451 An in vitro and clinical assessment of a nonadherent, antim...EWMAConference
Sharon Lindsay, Alexander Waite, Rachael McInnes, Breda Cullen, Systagenix, Gargrave, UK
Robert J. Snyder, DPM, MSc, CWS, Professor, Barry University SPM, Miami Shores, Florida, USA
1) Laboratory tests found that bacteria died within hours of contact with copper alloy surfaces, with over 99.9% reduction in live bacteria.
2) A clinical trial found an 83% reduction in bacteria levels on copper alloy surfaces in hospital rooms compared to standard materials. Infection rates were 58% lower in rooms with copper components.
3) The article concludes that copper alloys have potential to reduce hospital-acquired infections and costs by continuously killing bacteria without human intervention.
Genetic engineering is the best technology that is promoting the world and this technology is applied to many plants, animals and microorganisms. It has wider applications in the field of Biology, Medicine, Industry, Research, Agriculture and many other fields of science. In this research paper I update the Roles of Genetic Engineering in Agriculture, Animals, Human enhancement and Evolution, Bacteriophage Against Infectious Diseases, Medicines, Phage in Infectious Diseases, Biofuels Production and Improve Plant Performance Under Drought.
Genetic Resistance to Infectious Diseases in the Era of Personalized Medicine...CrimsonpublishersCJMI
Genetic Resistance to Infectious Diseases in the Era of Personalized Medicine by Andrei Alimov in Cohesive Journal of Microbiology & Infectious Disease
This document describes the development of a multiplex PCR assay targeting the cgcA gene, which encodes a diguanylate cyclase, to differentiate between species within the genus Cronobacter. Analysis of 12 Cronobacter genomes identified 7 conserved diguanylate cyclase-encoding genes, one of which, cgcA, showed species-specific divergence that matched known phylogenetic relationships between Cronobacter species. Primers were designed for this gene and tested in a multiplex PCR assay on 305 Cronobacter isolates representing 6 species. The assay correctly identified the species of all isolates tested and did not identify any of 20 non-Cronobacter species, demonstrating high specificity and sensitivity for rapid identification of Cronobacter.
This document discusses antimicrobial resistance mechanisms in Staphylococcus aureus, specifically methicillin-resistant S. aureus (MRSA). MRSA infections are now responsible for more deaths per year in the US than HIV and add billions to healthcare costs worldwide. MRSA strains have developed diverse genetic elements that confer resistance to multiple antimicrobials like methicillin, aminoglycosides, erythromycin, and tetracycline. Certain MRSA strains are also resistant to additional drugs including fluoroquinolones. Effective antimicrobial therapy is threatened as S. aureus continues developing resistance.
SIV Viral Variation; Implications for Vaccines and Transmission - Mars Stone PhDMars Stone
SIV Viral Variation; Implications for Vaccines and Transmission
PART 1 Viral diversity at mucosal transmission
-determine if vaginal SIV inoculation of rhesus macaques
recapitulates HIV-1 variant transmission
PART 2 Viral diversity in vaccine setting
-Characterize the replication levels and anatomic distribution of vaccine (SHIV 89.6) and challenge (SIVmac239) virus in monkeys prior to and after challenge.
-Characterize evolution of SIV env population complexity of SIV DNA in PBMC of SHIV immunized and control animals
Sarah Fox-Greer is seeking an industrial scientist position where she can apply her strong expertise in pharmacology, inflammation biology, and immunology gained over a decade of lab experience. She has a Ph.D. in cation exchanged zeolites as storage materials for nitric oxide and their therapeutic potential, and has extensive experience isolating and culturing various cells, performing assays and techniques such as flow cytometry and confocal imaging. Her research has focused on investigating pathways involved in apoptotic cell clearance and the progression of inflammation, and the potential of CDK inhibitor drugs as anti-inflammatory therapeutics. She has mentored students and published multiple papers in peer-reviewed journals.
This document summarizes different levels of host susceptibility that can contribute to dysbiosis. At the microbial level, controlled inflammation allows commensals to coexist while pathogens subvert the immune response. At the host tissue level, the response to biofilm formation and genetic and immunological factors determine susceptibility. At the systemic level, periodontal bacteria and their toxins can enter the bloodstream and contribute to inflammation in distant sites, while reduced oxygen pressure allows pathogens to thrive. The key points are that the host drives pathogen variation and it is unclear if periodontitis should be resolved through treating the infection or inflammation.
1. The document lists 29 publications with the author Lu Y, demonstrating their expertise in biomedical research related to neurodegenerative diseases and therapeutic antibody development.
2. Many of the publications focus on characterizing antibody delivery across the blood-brain barrier and targeting proteins involved in diseases like Alzheimer's.
3. The publications span from 2004 to the present and represent collaborative work with numerous co-authors investigating topics like antibody pharmacokinetics and biomarkers.
This document discusses the complex relationship between the host and microbes in the context of periodontal disease. It addresses three levels of interaction: (1) at the microbial level where controlled inflammation benefits commensals; (2) at the host tissue level where the host responds to biofilm formation through immune and inflammatory factors as well as genetic factors; and (3) at the systemic level where dysbiosis can lead to conditions in other parts of the body. The document questions whether periodontal pathogens are generalists or specialists and whether the goal of treatment is to resolve the infection or the inflammation. It ultimately emphasizes that the host plays a key role in driving pathogen variation and the development of periodontal disease.
1. This document lists original articles and book chapters published by Dr. Lee BC and collaborators related to hematopoietic stem cells and cancer.
2. The publications span from 1988 to 2017 and cover topics such as the role of specific genes and receptors in regulating hematopoietic stem cells and their response to stressors like radiation.
3. Many of the articles examine how the bone marrow microenvironment influences hematopoietic stem cells through factors secreted by other cell types.
This document is a curriculum vitae for Hui Zhang, a professor at Johns Hopkins University School of Medicine. It lists his current appointments, education history, professional experience, and publications. Specifically, it details that he is currently a professor in the Department of Pathology at JHU and director of the Mass Spectrometry Core Facility. It provides information on his education from Beijing University and University of Pennsylvania. It also lists over 45 publications in peer-reviewed journals related to proteomics and mass spectrometry research.
This study aimed to differentiate between invasive squamous cell carcinoma (SCC) and carcinoma-in-situ (CIS) of the uterine cervix using immunohistochemical markers. Tissue samples from 37 patients were stained for CD3, CD4, CD8, CD20, and CD138. Scoring showed decreased expression of CD8, CD20, and CD138 in invasive SCC compared to CIS, indicating differences in immune cell infiltration between invasive and non-invasive lesions. The results provide potential markers for differentiating invasive SCC from CIS of the cervix.
This curriculum vitae summarizes the professional experience and qualifications of Michael John Dewey. It lists his education, including a Ph.D. in Microbiology from the University of Pennsylvania in 1973. It details his professional roles, such as Instructor at Colorado State University since 2007 and various director positions. It also provides a selection of his 75 publications in peer-reviewed journals on topics related to genetics and microbiology research.
This document summarizes Misael Fernandez's study of the lung microbiome in chronic obstructive pulmonary disease (COPD) patients using metagenomic sequencing. It describes the modular analytical workflow used, including data preprocessing, classification, single and multiple sample analysis. It shows differences in microbial richness and diversity between COPD patients, smokers, and never smokers. The most abundant genera in COPD patients are identified. The study provides insights into differences in the lung microbiome between patient groups.
Publications - Martha A. Waters, PhD, MPH, CIH, FAIHAmarthawaters
This document provides a list of publications by Martha A. Waters, PhD, MPH, CIH, FAIHA. The list includes 20 peer-reviewed journal articles from 2015-2020 that Waters was an author on, covering topics like occupational exposure to solvents and risk of birth defects, PCB exposure among capacitor manufacturing workers, and cosmic radiation exposure estimates for flight attendants.
Publications, Book Chapters, And Selected Patentsazilberstein
This document lists 45 publications authored by Asher Zilberstein and collaborators from 1974 to 1994. The publications investigate the mechanisms of interferon action and interferon-induced inhibition of protein synthesis. They also examine the effects of tyrosine kinase inhibitors on cell proliferation, signal transduction pathways involving growth factors and their receptors, and phosphorylation events. The list demonstrates Zilberstein's extensive research on interferons, protein kinases, and growth factor signaling over a 20 year period.
Publications, Book Chapters, And Selected Patentsazilberstein
This document lists 45 publications authored by Asher Zilberstein and collaborators from 1974 to 1994. The publications investigate the mechanisms of interferon action and interferon-induced inhibition of protein synthesis. They also examine the effects of tyrosine kinase inhibitors on cell proliferation, signal transduction pathways involving growth factors and their receptors, and phosphorylation events. The list demonstrates Zilberstein's extensive research on interferons, protein kinases, and growth factor signaling over a 20 year period.
This document provides a publication list for W.G.E.J. Schoonen from 2016-2007. It includes over 50 publications with Schoonen as an author, ranging from journal articles to book chapters. The publications cover a variety of topics including in vitro toxicity testing methods, high-throughput screening, mechanisms of genotoxicity and carcinogenicity, and applications of toxicology in the pharmaceutical industry.
Publications v10 - Martha A. Waters, PhD, MPH, CIH, FAIHADrMarthaWaters
This document provides a list of 16 publications by Martha A. Waters related to occupational exposures and health outcomes. The publications cover topics such as cancer incidence among workers exposed to polychlorinated biphenyls, occupational exposure to chlorinated solvents and kidney cancer, maternal occupational exposure to polycyclic aromatic hydrocarbons and birth defects, and cancer risk among airline pilots from cosmic radiation exposure. The list demonstrates Waters' extensive research investigating relationships between occupational exposures and cancer, birth defects, and other health effects.
This document summarizes several research studies on various antibiotics and antimicrobial agents. It discusses penicillin and its derivatives as immune response triggers. It also looks at hypersensitivity reactions to beta-lactam antibiotics in children and methods of synthesis and molecular modeling of cephalosporins. Additional articles summarize the pH potential of antimicrobials under environmental and light factors, glycopeptides in clinical development, targeting the bacterial cell wall, mechanisms of antimicrobial resistance, and dalbavancin origin and activity. Further articles address tigecycline, fluoroquinolones, tuberculosis treatment, rifaximin, shortening treatment for tuberculosis, polymyxin B sulfate, colistin, mechanisms of newer antibiotics
This document contains summaries of several research articles and publications related to the treatment of chronic lymphocytic leukemia using nanoparticles, photodynamic therapy, and mesenchymal stem cells. Many of the publications were authored or co-authored by Eduardo Mansilla and focus on developing new therapeutic approaches for blood cancers using nanotechnology and regenerative medicine techniques.
This document lists 40 publications with the author Yong Gao. Many of the publications are about HIV and hepatitis C virus (HCV) research including studies on:
1) Demonstrating the safety of a killed whole-HIV vaccine in a clinical trial and its ability to enhance anti-HIV antibody responses.
2) Characterizing macaque infection by a clone from a diverse SHIVenv pool derived from acute HIV infections.
3) Studying pathogenic infection of rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV infections.
4) Research on HIV diversity, recombination, and disease progression.
This document lists 13 scientific publications that involve researcher S. Hadidi. The publications span from 2000-2013 and cover topics such as: identifying genetic factors related to disease resistance in rainbow trout; examining the role of the protein Ship1 in regulating immune responses to helminth infections; investigating the functions of the histone methyltransferase G9a in T cell differentiation; studying genetic selection for bacterial cold water disease resistance in trout; identifying Toll-like receptor genes in trout; and exploring the role of spleen size in disease resistance of trout. Many publications also involve examining the regulatory functions of the protein MD-1.
This document lists publications and abstracts by David C. Fritzinger Ph.D. relating to research on cobra venom factor (CVF) and its role in activating the complement system. It includes 23 peer-reviewed publications from 1994-2015 describing molecular cloning and structure-function analysis of CVF and development of humanized CVF proteins for therapeutic complement depletion. It also lists 25 conference abstracts from 2009-2016 presenting research on using humanized CVF to deplete complement in preclinical disease models and potential therapies.
Cell_A global metagenomic map of urban microbiomesand antimicrobial resistanc...ssuser4bd7ad
This study presents a global metagenomic atlas of 4,728 samples from mass transit systems in 60 cities over 3 years, representing the first systematic catalog of urban microbiomes worldwide. The atlas provides a profile of microbial strains, genes, and other genetic elements found in cities, including over 10,000 viruses and 1,300 bacteria. A consistent set of 31 microbial species was identified in 97% of samples. Profiles of antimicrobial resistance genes varied widely between cities and were influenced by climate and geography. This high-resolution atlas enables discovery of novel organisms and genes in urban environments and provides insight into public health issues like antimicrobial resistance in cities.
Cell_A global metagenomic map of urban microbiomesand antimicrobial resistanc...
Publication list March 2016
1. Llinos GHarris - Curriculum Vitae
March 20161
Publication list
Harris LG,Murray S, Pascoe B,Bray JE,Méric G, MageirosL, WilkinsonTS,JeevesR,Rohde H,SchwarzS, de
Lencastre H, Miragaia M, RoloJ, BowdenR,Jolley KA,MaidenMCJ,Mack D, SheppardSK.Biofilmmorphotypes
and populationstructure among Staphylococcusepidermidis fromcommensalandclinical samples.PLoSOne
2016;11:e0151240
Al-IshaqR,ArmstrongJ,GregoryM, O'Hara M, Phiri K, Harris LG,Rohde H, SiemssenN,FrommeltL,Mack D,
WilkinsonTS.Effectsof polysaccharideintercellularadhesin(PIA)inanex vivomodel of whole bloodkillingandin
prostheticjointinfection(PJI):A role forC5a. IntJ Med Microbiol. 2015;305:948-56
Méric G, Miragaia M, de BeenM, Yahara K, Pascoe B, Mikhail J, Harris LG, Wilkinson TS, Rolo J, Lamble S, Bray JE,
Jolley KA, Hanage WP, Bowden R, Maiden MCJ, Mack D, de Lencastre H, Feil EJ, Corander J, Sheppard SK
Ecological overlap and horizontal gene transfer in Staphylococcus aureus and Staphylococcus epidermidis.
Genome Biol Evol. 2015;16;7:1313-28.
Pascoe B, Dams L, Wilkinson TS, Harris LG, Bodger O, Mack D, Davies AP (2014). Dormant cells of Staphylococcus
aureus are resuscitated by spent culture supernatant. PLoS One 2014;9:e8599.
Harris LG, Nigam Y, Sawyer J, Mack D, Pritchard DI. Lucilia sericata chymotrypsin disrupts protein adhesin-
mediated staphylococcal biofilm formation. Appl Environ Microbiol. 2013;79:1393-1395.
Mack D, Davies AP, Harris LG, Jeeves R, Pascoe B, Knobloch JKM, Rohde H, Wilkinson TS. Staphylococcus
epidermidis in biomaterial-associated infections (Book chapter). In Moriarty, T.F., Zaat, S.A.J. & Busscher, H.J.
(Eds.), Biomaterials Associated Infection (2013, Part 1, 25-56) Publisher: Springer New York, ISBN: 978-1-4614-
1031-7.
DaviesAP,ReidM, HadfieldSJ,JohnstonS,Mikhail J, HarrisLG, JenkinsonHF,BerryN,LewisAM, El-Bouri K, Mack
D. Identificationof clinical isolatesof α-hemolyticstreptococci by16S rRNA gene sequencing,matrix-assistedlaser
desorption ionization-time of flight mass spectrometry using MALDI biotyper, and conventional phenotypic
methods: a comparison. J Clin Microbiol. 2012;50:4087-90.
El-Bouri K,JohnstonS,ReesE, ThomasI, Bome-MannathokoN, Jones C, Reid M, Ben-Ismaeil B, Davies AP, Harris
LG, Mack D. Comparisonof bacterial identificationbyMALDI-TOFmassspectrometryandconventional diagnostic
microbiology methods: agreement, speed and cost implications. Br J Biomed Sci. 2012;69(2):47-55.
SpiliopoulouAI,KrevvataMI, Kolonitsiou F, Harris LG, Wilkinson TS, Davies AP, Dimitracopoulos GO, Karamanos
NK, Mack D, Anastassiou ED. An extracellular Staphylococcus epidermidis polysaccharide: relation to
Polysaccharide Intercellular Adhesin and its implication in phagocytosis. BMC Microbiol. 2012;12:76.
Harris LG, El-Bouri K,JohnstonS,ReesE, FrommeltL,SiemssenN,ChristnerM,DaviesAP,Rohde H,Mack D.
Rapididentificationof staphylococcifromprostheticjointinfectionsusingMALDI-TOFmass-spectrometry.IntJ
Artif Organs2010; 33: 568–574.
Jukes L, Mikhail J, Bome-Mannathoko N, Hadfield SJ, Harris LG, El-Bouri K, Davies AP, Mack D. Rapid
differentiationof Staphylococcusaureus, Staphylococcusepidermidis andothercoagulase negative staphylococci
and meticillinsusceptibilitytestingdirectlyfromgrowth-positive bloodculturesbymultiplex real-time PCR. J Med
Microbiol 2010; 59: 1456–1461.
Harris LG,Bexfield A,NigamY,Rohde H, Ratcliffe NA, Mack D. Disruption of Staphylococcus epidermidis biofilms
by medicinal maggot Lucilia sericata excretions/secretions. Int. J. Artif. Organs 2009; 32, 555-564.
Mack D, DaviesAP, Harris LG,KnoblochJKM,Rohde H. Staphylococcusepidermidis biofilms:functional molecules,
relation to virulence, and vaccine potential. Top. Curr. Chem. 2009; 288, 157-182.
Samek,O.,H. H. Telle, L.G. Harris, M. Bloomfield,andD.Mack. 2008. Raman spectroscopyforrapid
discriminationof Staphylococcusepidermidis clonesrelatedtomedical device-associatedinfections.
Laser Phys.Lett. 5:465-470.
HudetzD, HudetzSU, Harris LG,Luginbühl R,FriederichNF,LandmannR. Weak effect of metal type and ica gene
expression on staphylococcal infection of titanium and stainless steel implants. Clin Microbiol Infect.
2008;14:1135-1145.
2. Llinos GHarris - Curriculum Vitae
March 20162
Maddikeri RR, Tosatti S, Schuler M, Chessari S, Textor M, Richards RG, Harris LG (2008) Effect of modifying
titanium surfaces with PLL-g-PEG and RGD-functionalised PLL-g-PEG on bacterial adhesion. J Biomed Mat Res
84A:425–435.
Hübscher J, Jansen A, Kotte O, Schäfer J, Majcherczyk PA, Harris LG, Bierbaum G, Heinemann M, Berger-Bächi B
(2007) Living with an imperfect cell wall: Compensation of femAB inactivation in Staphylococcus aureus. BMC
Genomics 8:308.
Harris LG, MeredithDO,Eschbach L, RichardsRG (2007) Staphylococcusaureus adhesiontostandardmicro-rough
and electropolished implant materials. J Mat Sci Mat Med 18:1151-1156.
Rohde H, BurandtEC, SiemssenN,FrommeltL,Burdelski C,WursterS,Scherpe S,DaviesAP, Harris LG, Horstkotte
MA, Knobloch JKM, Kaplan JB, Mack D (2007) Differential importance of polysaccharide intercellular adhesin or
protein factors in biofilm accumulation of Staphylococcus epidermidis and Staphylococcus aureus isolated from
prosthetic hip and knee joint infections. Biomaterials 28: 1711-1720.
Mack D, Davies AP, Harris LG, Rohde H, Horstkotte MA, Knobloch JKM (2007) Microbial interactions in
Staphylococcus epidermidis biofilms. Anal Bioanal Chem 387:399-408.
Harris LG, Richards RG (2006) Staphylococci and implant surfaces: a review. Injury, 37:S3-14.
Mack D, Rohde H, Harris LG, Davies AP, Horstkotte MA, Knobloch JKM. (2006) Biofilm formation in medical
device-related infection Int J Artif Organs 29:343-359.
Harris LG,Mead L, Mueller-OberlanderE,RichardsRG (2006) Bacteriaand cell cytocompatibilitystudiesoncoated
medical grade titanium surfaces. J Biomed Mat Res 78A:50-58.
Seidl K, Stucki M, Ruegg M, Görke C, Wolz C, Harris LG, Berger-Bächi B, Bischoff M (2006) The Staphylococcus
aureus CcpA homologue affectsvirulence determinant production and antibiotic resistance. Antimicrob Agents
Chemother 50:1183-1194.
Harris LG,Gorna K, Gogolewski S,RichardsRG(2006) Biodegradable polyurethanecytocompatibilitytofibroblasts
and staphylococci. J Biomed Mat Res 77A:304–312.
Harris LG, Richards RG (2005). Implant coatings to prevent infection. AO Dialogue 18:23-24
Harris LG, Patterson LM, Bacon C, ap Gwynn I, Richards RG (2005). Assessment of the cytocompatibility of
different coated titanium surfaces to fibroblasts and osteoblasts. J Biomed Mat Res 73A:12-20.
ReinhartWH, PleischB, Harris LG,Lutolf M (2005). Influenceof contrastmedia(iopromide,ioxaglate,gadolinium-
DOTA) on bloodviscosity,erythrocyte morphologyandplateletfunction.ClinHemorheolMicrocirc32:227-239.
Harris LG,RichardsRG (2004). Staphylococcusaureus adhesiontodifferenttreatedtitaniumsurfaces. JMatSci
Mat Med 15:311-314.
Harris LG, Tosatti S, Richards RG, Textor M (2004). Staphylococcus aureus adhesion to titanium oxide surfaces
coatedwithnon-functionalizedandpeptide-functionalizedpoly(L-lysine)-graft-poly(ethylene glycol) copolymers.
Biomaterials, 25:4135-4148.
Harris LG, FosterSJ, RichardsRG (2002). An introductionto Staphylococcusaureus,andtechniquesforidentifying
and quantifying S. aureus adhesins in relation to adhesion to biomaterials: Review. Eur Cells Mat 4:39-60.
Clarke SJ, Harris LG, Richards RG, FosterSJ(2002). Analysisof Ebh,a 1.1 megaDaltonsurface, fibronectin binding
protein of Staphylococcus aureus. Infect Immun 70:6680-6687.
Bundy KJ, Harris LG, Rahn BA, Richards RG (2001). Measurement of fibroblast and bacterial detachment from
biomaterials using jet impingement. Cell Biol Int 25:1237-1249.
Mark M, Walter R, Harris LG, Reinhart WH (2000). Influence of parathyroid hormone, calcitonin, 1,25(OH)2
cholecalcifeol,calcium,andthe calciumionophore A23187 on erythrocyte morphology and blood viscosity. J Lab
Clin Med 135:347-352.
WalterR, Mark M, GaudenzR, Harris LG,ReinhartWH (1999). Influence of nitrovasodilators and endothelin-1 on
rheology of human blood in vitro. Br J Pharmacol 128:744-750.
Harris LG, ap Gwynn I, Richards RG (1999). Contrast optimisation for backscattered electron imaging of resin
embedded cells. Scan Micro 13:71-81.
3. Llinos GHarris - Curriculum Vitae
March 20163
Presentation list
Oral presentations
June 2015. Staphylococcus epidermidis, commensal to pathogenic? at ECMXVI, Davos, Switzerland.
June 2015. Populationgenomicsof Staphylococcusepidermidis,atthe ColegCymraegCenedlaethol 4th
Scientific
Conference,Aberystwyth,Wales,UK.
October2014. Medicinal maggot Lucilia sericata excretions/secretionsandtheireffectonbiofilms,at1st
iPROMEDAIworkshop,Porto,Portugal.
September 2014. Variation between implant associated and commensal Staphylococcus epidermidis, at 5th
Thesinge Biofilm meeting, Thesinge/Groningen, The Netherlands.
September 2013. Population genomics of Staphylococcus epidermidis, at Staph GBI 2013, Dublin, Ireland.
June 2011. Influence of biomaterials on Staphylococcus epidermidis biofilm formation, at ECMXII, Davos,
Switzerland.
July2010. Staphylococcusepidermidis biofilmdisruption by Lucilia sericata excretions/secretions, at the ENTO10
meeting in Swansea, UK.
November2009. Quorumsensing agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and
catheter infections, at Infection 2009, Birmingham, UK.
March 2009. Species identification in Staphylococcus using MALDI-ToF/MS, at SGMSpring meeting, Harrogate,
UK.
March 2009. Quorum sensing agr-specificity groups in Staphylococcus epidermidis from prosthetic joint and
catheter infections, at SGMSpring meeting, Harrogate, UK.
September 2008. Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata
excretions/secretions, at the 13th International Symposium on Staphylococci and Staphylococcal Infections
(ISSSI), Cairns, Australia.
July 2008. Staphylococcus epidermidis biofilm disruption by medicinal maggot Lucilia sericata
excretions/secretions, at Staphylococcus GBI 2008, Leeds, UK.
Sept2006. Influence of biomaterialsonStaphylococcusbiofilm formation, at 12th
ISSSI, Maastricht, Netherlands.
April 2006. Biofilm formation of Staphylococcus epidermidis, at StaphGBI 2006, Liverpool, UK.
September 2005. Bacterial Reactions to Modified Biomaterial Surfaces, at Biosurf VI, Lausanne, Switzerland
(Invited speaker).
September2005. Staphylococci adhesiontocoatedtitanium surfaces impregnated with an antiseptic, at the 19th
European Conference on Biomaterials, Sorrento, Italy.
September 2005. Studying bacterial adhesion to biomaterials, at Microscopy 2005, Davos, Switzerland.
July 2005. Staphylococci and implants, at Medical School Seminar, Swansea University, Swansea, Wales, UK
(Invited speaker).
May 2005. Cytocompatibility of coated titanium surfaces impregnated with an antiseptic to staphylococci and
fibroblasts, at the 24th European Bone and Joint Infection Society, Ljubljana, Slovenia.
January 2005. Staphylococci and Implants, at the Institute of Medical Microbiology, University of Zurich, Zurich,
Switzerland (Invited speaker).
November2004. Staphylococcusaureus andmodifiedcoatedtitaniumimplants,atthe 14th
EuropeanOrthopaedic
Research Society, Amsterdam, the Netherlands.
October 2004. Bacterial Adhesion to Implantable Materials, at XIV Conference on Biomaterials in Medicine and
Veterinary medicine, Rytro, Poland.
June 2004. Analysingbacterial adhesiontobiomaterialsatthe EuropeanCellsandMaterialsV conference, Davos,
Switzerland (Invited speaker).
4. Llinos GHarris - Curriculum Vitae
March 20164
April 2004. The race for the surface: Bacteria and cell interaction with artificial materials, at Swiss Federal
Laboratory for material Testing and Research, EMPA, St Gallen, Switzerland (Invited speaker).
September 2003. Staphylococcus aureus adhesion to different treated titanium surfaces, at 18th
European
Conference on Biomaterials, Stuttgart, Germany.
May 2003. The effect of hydrophilicity of implantable biodegradable polyurethanes on cell and bacteria
cytocompatibility, at AO Research Institute, Davos, Switzerland.
November 2002. Molecular analysis of Staphylococcus aureus adhesins, at AO Research Institute, Davos,
Switzerland.
August 2002. Bacteria and Biomaterials, at ETH Zurich, Zurich, Switzerland (Invited speaker).
October 2001. Staphylococcus aureus surface protein topography, at Robert Mathys Foundation, Bettlach,
Switzerland.
June 2001. Staphylococcusaureus surface proteintopography,atthe EuropeanCellsand Materials II conference,
Davos, Switzerland (winner of the best presentation award).
Poster presentations
September2015. Harris LG,Pascoe B, Meric G, Murray S,MageriosL, Mack D, Schwarz S,de Lancastre H, Bowden
R, SheppardSK. Staphylococcusepidermidis,commensal topathogenic?at StaphGBI 2015, Reading,UK.
January2015. Harris LG,Pascoe B, Meric G, Murray S,MageriosL, Mack D, de Lancastre H, Schwarz S,BowdenR,
SheppardSK. Commensal topathogenic,how?,atMITReG annual meeting,Cardiff,UK.
December2013. Harris LG, Pascoe B, Rohde H, Mack D, SchwarzS, de Lancastre H, Miragaia M, RoloJ, BowdenR,
SheppardSK. Temporal variationinclinical coagulase negative staphylococci,atMITReG annual meeting,
Swansea,UK.
April 2013 Harris LG, Jeeves,R,Rohde H,Mack D, Sheppard SK. Staphylococcus epidermidis biofilm formation on
indwelling medical devices, at ECCMID 2013, Berlin, Germany.
March 2012. Harris LG, Jeeves, R, Rohde H, Mack D. Influence of biomaterials on Staphylococcus epidermidis
biofilm formation, at the SGMSpring meeting in Edinburgh, UK.
March 2012. Jeeves R, Harris LG, Mack D. Collagen Binding Factors in Clinical Isolates of Staphylococcus
epidermidis, at the SGMSpring meeting in Edinburgh, UK.
July2011. Harris LG, Jeeves,R,Rohde H,Mack D Influenceof biomaterialson Staphylococcus epidermidis biofilm
formation, at the Gordon Staphylococcus Diseases Conference, Braga, Italy.
September2010. Harris LG,DudleyE,Rohde H, Mack D. agr-specificitygroupsin Staphylococcusepidermidis from
prosthetic joint and catheter infections, at 14th
ISSSI, Bath, UK.
April 2010. SpiliopoulouAI, Krevvata MI, Kolonitsiou F, Harris LG, Wilkinson TS, Davies AP, Dimitracopoulos GO,
KaramanosNK,Mack D, AnastassiouED.Relationbetween20-kDapolysaccharide andPolysaccharide Intercellular
Adhesin of Staphylococcus epidermidis, at ECCMID 2010, Vienna, Austria.
November 2009. Bome-Mannathoko N, Wooton M, Harris LG, Howe R, Mack D. Molecular characterisation of
Panton-Valentine Leukocidin (PVL)-positive Staphylococcus aureus from Wales, at Infection 2009, Birmingham,
UK.
2009. JukesL,Mikhail J,HadfieldS, Harris LG, El-Bouri K,DaviesAP,Mack D. Rapid identification of staphylococci
and methicillinsusceptibility testing directly from growth positive blood cultures by real-time PCR, at Infection
2009, Birmingham, UK.
November2009. JonesC, Harris LG, ReesE, El-Bouri K, DaviesAP,Mack D. Molecularepidemiologyof extended-
spectrum β-lactamase (ESBL) carrying Enterobacteriaceae in Swansea, at Infection 2009, Birmingham, UK.
September 2009. Harris LG,, Dudley E, Rohde H, Mack D. agr-specificity groups in Staphylococcus epidermidis
from prosthetic joint and catheter infections, at Gordon Staphylococcus Diseases Conference, Waterville, NH.
USA.
5. Llinos GHarris - Curriculum Vitae
March 20165
September 2008. Harris LG, Bexfield A, Nigam Y, Rohde H, Ratcliffe NA, Mack D. Disruption of Staphylococcus
epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions, at 13th
ISSSI, Cairns, Australia.
July 2008. Bome-Mannathoko N, Harris LG, Hadfield S, Shepherd C, Johnston S, Rees E, El-Bouri K, Davies AP,
Mack D. Performance of SCCmec-orfX amplification and prevalence of Panton-Valentine Leukocidin (PVL) in
Staphylococcus aureus from wound and skin specimens, at Staphylococcus GBI 2008, Leeds, UK.
March 2007. Hübscher J, Jansen A, Kotte O, Schäfer J, Majcherczyk PA, Harris LG, Bierbaum G, Heinemann M,
Berger-Bächi B. Compensation of femAB deletion in Staphylococcus aureus: A strategy to survive with an
imperfect cell wall, at 160th
Society for General Microbiology meeting, Manchester, UK.
Sept 2006. Harris LG, Rohde H, Knobloch JKM & Mack D. Influence of biomaterials on Staphylococcus biofilm
formation, at 12th
ISSSI, Maastricht, Netherlands.
Sept2006. Maddikeri R,Tosatti S, RichardsRG & Harris LG. Bacterial adhesion to PLL-g-PEG modified surfaces, at
20th
European Conference on Biomaterials, Nantes, France.
Sept2005. Maddikeri R,Tosatti S, Richards RG & Harris LG. Bacterial adhesion to PLL-g-PEG modified Ti surfaces,
at Biosurf VI, Lausanne, Switzerland.
June 2005. Harris LG, Mead L, Mueller-OberlanderE& RichardsRG. Cytocompatibilityof coatedtitaniumsurfaces
impregnated with an antiseptic, at 11th General meeting of the Swiss Society for Biomaterials, Mägenwil,
Switzerland.
July2004. Harris LG, Gorna K,Gogolweski S& RichardsRG. Cytocompatibility of biodegradable polyurethanes to
cells and bacteria, at 10th General meeting of the Swiss Society for Biomaterials, Davos, Switzerland.
May 2004. Harris LG, Gorna K, Gogolweski S, & Richards RG. Cell and bacteria cytocompatibility on different
hydrophilic biodegradable polyurethanes, at 7th
World Biomaterials conference, Sydney, Australia.
September2003. Harris LG, Gorna K, Gogolweski S, & Richards RG. Effect of different hydrophilic polyurethanes
on cell and bacterial adhesion, at Biosurf V, Zurich, Switzerland.
May 2003. Harris LG, Tosatti S, Richards RG & Textor M. Staphylococcus aureus adhesion to different modified
titanium surfaces, at Interface Biology symposium, Rostock, Germany.
June 2003. PattersonL, Harris LG,ap GwynnI. & Richards RG. Fibroblastadhesion&morphology on titanium and
TAN withvarioussurface treatments, at 9th General meeting of the Swiss Society for Biomaterials, Neuachatel,
Switzerland.
June 2003. Bühler M, Harris LG, Zinger O, Landolt D & Richards RG. Characterisation of fibroblast adhesion on
titaniummodel surfaces,at9thGeneral meetingof the Swiss Society for Biomaterials, Neuachatel, Switzerland.
June 2003. Bacon C, Harris LG, ap GwynnI & RichardsRG. Osteoblastadhesion&morphologyand Staphylococcus
aureus on various coated orthopaedic implant surfaces, at 9th General meeting of the Swiss Society for
Biomaterials, Neuachatel, Switzerland.
September 2002. Harris LG, Tosatti S, Foster SJ, Richards RG & Textor M. Staphylococcus aureus adhesion to
biomaterials, at Society for General Microbiology conference, Loughborough, UK.
September 2001. Harris LG, Richards RG & Foster SJ. Staphylococcus aureus surface protein topography, at the
StaphUK conference, Leicester, UK.
August 2001. Clarke SR, Brummell K, McDowell P, Harris LG & Foster SJ, at the Gordon Staphylococcal Diseases
conference, Rhode Island, USA.
April 1998. Harris LG, ap Gwynn I & Richards RG. Contrast optimisation for backscattered electron imaging of
resinembeddedcells,atthe ScanningElectronMicroscopyconference,Universityof Wales,Aberystwyth, Wales,
UK.