PRISM

1. 曹 永 孝
西安交大医学院药理学系
科教楼805；yxy@xjtu.edu.cn; 82655140
http://gr.xjtu.edu.cn:8080/web/yxy
GraphPad Prism

2. GraphPad Prism
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than 100,000 scientists in over 100 countries rely on Prism to analyze,
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3. 7.5 7.6 7.7 7.8 7.9
7.2
7.4
7.6
7.8
MOPS 缓冲母液 pH 值
MOPS
液
pH
值

4. -8 -7 -6 -5
0
50
100
150
200
DSP 0.2¦Ìl/ml
DMSO 0.2¦Ìl/ml
DSP 0.2¦Ìl/ml
DMSO 0.2¦Ìl/ml
A
NE (log M)
Contraction
(%
of
K
+
)

5. -10 -9 -8 -7
0
100
200
300
fresh
culture
culturing with mmLDL **
A
##
**
**
**
**
culturing with LDL
Sarafotoxin 6c (log M)
Contraction
(%
of
K
+
)
##
##
##
##

6. 1A
Control EF-1 GAPDH
0
25
50
75
100
125
DSP 0.2μl/ml
A
*
**
Amount



receptor
mRNA
relative
to
House
Keeping
Gene
(%
of
Control)

7. 0
50
100
150
200
Vehicle
SP600125
***
***
***
*
BK ACh 5-HT ET-1
E
m
ax
(%
of
K
+
)

8. Max contraction and pD2 of angiotensin on incubated mesenteric artery of rat
Fresh Incubated 1d Incubated 2d
0
40
80
120
0
2
4
6
8
10
Max contraction
pD2
Contraction
(%
of
K
+
)
pD
2

9. 0 2 4 6 8
0
20
40
60
80
100
Control
Cefazedone10 mg/kg
Cefazedone20 mg/kg
Cefazedone40 mg/kg
Fig. 1 The protective effect of cefazedone sodium on mice infected with
escherichia coli R1598
Cefazolin
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