A 50-year-old female presented with an incidental 2x3 cm paraesophageal mass found on CT during a hematuria workup. FDG PET showed intense focal uptake in the mass concerning for metastatic lymph node or esophageal cancer. Biopsies were nondiagnostic. VATS showed necrotizing granuloma suggestive of fungal infection, likely histoplasmosis. Treatment with itraconazole led to a significant decrease in FDG avidity on follow-up PET-CT, indicating histoplasmosis rather than cancer. This case demonstrates that focal FDG uptake can be caused by fungal infection, which should be considered in the differential diagnosis of possible esophageal cancer.
CANCER of UNKNOWN PRIMARY (CUP), Dr BÙI ĐẮC CHÍhungnguyenthien
Cancer of unknown primary (CUP) refers to metastatic cancer that has spread to other parts of the body but the original primary site cannot be identified. CUP makes up approximately 2-6% of cancer cases. Conventional methods to identify the primary site include imaging scans, medical history, physical exams, and laboratory tests. Molecular profiling using techniques like immunohistochemistry, gene expression profiling, and next generation sequencing can identify predictive biomarkers and actionable targets in around 80% of CUP cases. Identifying the primary site can help determine the best treatment approach and predict outcomes. Gene expression profiling tests like the Pathwork Tissue of Origin test can determine the likely tissue of origin with 99% certainty when the highest similarity score is above
According to the World Health Organization (WHO) prostate cancer is the second cause of cancer death in men worldwide [1,2]. Some advanced prostate cancers have well known symptoms. However non-cancerous diseases of the prostate, such as benign prostatic hyperplasia (BPH) cause same symptoms. On the other hand, at very early stages, prostate cancer has no symptoms, the tumor dimension is quite small, and it is extremely difficult to detect it. If prostate cancer is detected at an early stage, it can be successfully cured by different methods. At the later stages, treatment or surgery has very low efficiency. Prostate cancer can often be found by measuring the amount of PSA in the blood. Most healthy men have levels under 4 nano-grams per milliliter (ng/mL) of blood. When prostate cancer develops, the PSA level usually goes above 4. However, for determination of the existence of cancer, some additional methods are used: for example: PSA velocity [3,4] and/or PSA density. Besides, measurement of the ratio of free to total PSA is additional tool in prostate cancer diagnosis [5]. However, the major drawback of PSA determination is its relative lack of specificity. The PSA level can also be increased by benign prostate hyperplasia (BPH) - a noncancerous enlargement of the prostate, prostatitis, etc.
Cancer of Unknown Primary Origin (CUP) and its relation to HPV-associated oro...Robert Ferris
*Re-upload of slides originally posted 27th January 2019*
A presentation describing cancer of unknown primary (CUP), specifically in the head and neck region, its relation to human papillomavirus-associated OP cancer, and the clinical relevance of this link. Slides compiled as part of medical school studies.
Sources for all imagery and sources listed in references section where possible. I do not claim ownership of any images or graphics. Slides for educational purposes only, and should not replace clinical judgement. No monetary gain was made for this work.
This article discusses the risks associated with corneal transplantation from donors with a history of cancer. Specifically, it references a study that found one recipient developed prostate cancer 3 years after receiving a cornea from a donor with lymphoma. The article notes the limited understanding of cancer biology and need for further research on screening donors and the effects of chemotherapy. It concludes that while corneal transplantation provides benefits to patients, more information is needed to fully weigh the risks.
As the techniques that have enabled us to analyses and assess a biopsy become ever more sophisticated, we have realised the limitations of looking at the single snap-shot of the tumour. This single-biopsy bias was highlighted in which it was mainly demonstrated that a portion taken from different parts of a primary tumour and its metastases showed and proved extensive intertumoural and intratumoural evolution. This tumoural heterogeneity mainly highlights the difficulty of dictating a therapeutic course of action based on the single biopsy, as it is likely to underestimate the ramification of the genomic landscape of the tumour (Chomczynski et al., 2016).Having established that there is mainly considerable tumour heterogeneity, taking multiple biopsies from the patients‘ primary tumour and the metastases would seem to be the most obvious next step. There are so much difficulties in obtaining the tissue biopsy— including the discomfort suffered by the patient, the inherent clinical risks to the patient
Prostate MRI provides a remarkable advancement in prostate cancer diagnosis and treatment by allowing doctors to accurately visualize, characterize, and stage prostate cancers. Prior methods like PSA screening and random biopsies were inaccurate and missed many aggressive cancers. Prostate MRI uses different parameters on T2-weighted, diffusion-weighted, and dynamic contrast enhanced images to identify cancer nodules, determine their likelihood of being aggressive, and stage the cancer. This allows targeted biopsies to diagnose aggressive cancers earlier for better treatment outcomes while avoiding overdiagnosis of less concerning cancers. Prostate MRI is now central to diagnosis, treatment planning and monitoring in prostate cancer care.
A 50-year-old female presented with an incidental 2x3 cm paraesophageal mass found on CT during a hematuria workup. FDG PET showed intense focal uptake in the mass concerning for metastatic lymph node or esophageal cancer. Biopsies were nondiagnostic. VATS showed necrotizing granuloma suggestive of fungal infection, likely histoplasmosis. Treatment with itraconazole led to a significant decrease in FDG avidity on follow-up PET-CT, indicating histoplasmosis rather than cancer. This case demonstrates that focal FDG uptake can be caused by fungal infection, which should be considered in the differential diagnosis of possible esophageal cancer.
CANCER of UNKNOWN PRIMARY (CUP), Dr BÙI ĐẮC CHÍhungnguyenthien
Cancer of unknown primary (CUP) refers to metastatic cancer that has spread to other parts of the body but the original primary site cannot be identified. CUP makes up approximately 2-6% of cancer cases. Conventional methods to identify the primary site include imaging scans, medical history, physical exams, and laboratory tests. Molecular profiling using techniques like immunohistochemistry, gene expression profiling, and next generation sequencing can identify predictive biomarkers and actionable targets in around 80% of CUP cases. Identifying the primary site can help determine the best treatment approach and predict outcomes. Gene expression profiling tests like the Pathwork Tissue of Origin test can determine the likely tissue of origin with 99% certainty when the highest similarity score is above
According to the World Health Organization (WHO) prostate cancer is the second cause of cancer death in men worldwide [1,2]. Some advanced prostate cancers have well known symptoms. However non-cancerous diseases of the prostate, such as benign prostatic hyperplasia (BPH) cause same symptoms. On the other hand, at very early stages, prostate cancer has no symptoms, the tumor dimension is quite small, and it is extremely difficult to detect it. If prostate cancer is detected at an early stage, it can be successfully cured by different methods. At the later stages, treatment or surgery has very low efficiency. Prostate cancer can often be found by measuring the amount of PSA in the blood. Most healthy men have levels under 4 nano-grams per milliliter (ng/mL) of blood. When prostate cancer develops, the PSA level usually goes above 4. However, for determination of the existence of cancer, some additional methods are used: for example: PSA velocity [3,4] and/or PSA density. Besides, measurement of the ratio of free to total PSA is additional tool in prostate cancer diagnosis [5]. However, the major drawback of PSA determination is its relative lack of specificity. The PSA level can also be increased by benign prostate hyperplasia (BPH) - a noncancerous enlargement of the prostate, prostatitis, etc.
Cancer of Unknown Primary Origin (CUP) and its relation to HPV-associated oro...Robert Ferris
*Re-upload of slides originally posted 27th January 2019*
A presentation describing cancer of unknown primary (CUP), specifically in the head and neck region, its relation to human papillomavirus-associated OP cancer, and the clinical relevance of this link. Slides compiled as part of medical school studies.
Sources for all imagery and sources listed in references section where possible. I do not claim ownership of any images or graphics. Slides for educational purposes only, and should not replace clinical judgement. No monetary gain was made for this work.
This article discusses the risks associated with corneal transplantation from donors with a history of cancer. Specifically, it references a study that found one recipient developed prostate cancer 3 years after receiving a cornea from a donor with lymphoma. The article notes the limited understanding of cancer biology and need for further research on screening donors and the effects of chemotherapy. It concludes that while corneal transplantation provides benefits to patients, more information is needed to fully weigh the risks.
As the techniques that have enabled us to analyses and assess a biopsy become ever more sophisticated, we have realised the limitations of looking at the single snap-shot of the tumour. This single-biopsy bias was highlighted in which it was mainly demonstrated that a portion taken from different parts of a primary tumour and its metastases showed and proved extensive intertumoural and intratumoural evolution. This tumoural heterogeneity mainly highlights the difficulty of dictating a therapeutic course of action based on the single biopsy, as it is likely to underestimate the ramification of the genomic landscape of the tumour (Chomczynski et al., 2016).Having established that there is mainly considerable tumour heterogeneity, taking multiple biopsies from the patients‘ primary tumour and the metastases would seem to be the most obvious next step. There are so much difficulties in obtaining the tissue biopsy— including the discomfort suffered by the patient, the inherent clinical risks to the patient
Prostate MRI provides a remarkable advancement in prostate cancer diagnosis and treatment by allowing doctors to accurately visualize, characterize, and stage prostate cancers. Prior methods like PSA screening and random biopsies were inaccurate and missed many aggressive cancers. Prostate MRI uses different parameters on T2-weighted, diffusion-weighted, and dynamic contrast enhanced images to identify cancer nodules, determine their likelihood of being aggressive, and stage the cancer. This allows targeted biopsies to diagnose aggressive cancers earlier for better treatment outcomes while avoiding overdiagnosis of less concerning cancers. Prostate MRI is now central to diagnosis, treatment planning and monitoring in prostate cancer care.
The document discusses several studies related to lung cancer and DNA. It summarizes that mouse models show similarities to human lung cancer, allowing scientists to study disease progression. Researchers identified a gene called NF-Iβ associated with lung cancer. A separate study found specific DNA breakage characteristics in cancer cells. This molecular-level analysis improves understanding of cancer development and susceptibility.
The document discusses several studies related to lung cancer and DNA. It summarizes that mouse models show similarities to human lung cancer, allowing scientists to study disease progression. Researchers identified a gene called NF-Iβ associated with lung cancer. A separate study found specific DNA breakage characteristics in cancer cells. This molecular-level analysis improves understanding of cancer development and susceptibility.
The document discusses several studies related to lung cancer and DNA. It summarizes that mouse models show similarities to human lung cancer, allowing scientists to study disease progression. Researchers identified a gene called NF-Iβ associated with lung cancer. A separate study found specific DNA breakage characteristics in cancer cells. This molecular-level analysis improves understanding of cancer development and susceptibility.
The document discusses two recent discoveries related to genetics and disease. Researchers discovered a mechanism of gene silencing in hormone-dependent breast cancer cells involving a protein that interacts with the progesterone receptor and compacts chromatin. Scientists also discovered an X-chromosome inherited form of brittle bone disease osteogenesis imperfecta caused by two mutations in the MBTPS2 gene on the X chromosome, making men more vulnerable. These findings provide insights that can help improve diagnosis and treatment of these diseases.
Cancer Science & Research: Open Access is a journal that covers conventional and novel cancer treatment approaches through molecular targeting, especially for rare diseases. It aims to promote worldwide cancer research efforts to understand and combat the growing problem of cancer. The journal publishes research on various topics, including diffusion weighted MRI for evaluating prostate cancer response to treatment, detecting genomic instability in renal cancer through urine samples, antioxidants from Egyptian plants for cancer treatment, and biomarkers for personalized prostate cancer imaging and radiotherapy.
MRI is more accurate than other imaging modalities for ruling out prostate cancer. While PSA testing and biopsy are currently the standard for diagnosing prostate cancer, MRI has higher specificity and can better detect the location and extent of tumors, especially in men with elevated PSA and previous negative biopsies. The addition of MRSI to MRI further improves accuracy by distinguishing cancer from surrounding tissues based on metabolic profiles. Careful patient selection is important to maximize the clinical utility of MRI and MRSI for prostate cancer diagnosis and staging.
Vemurafenib in multiple nonmelanoma cancers with braf v600 shubhda royShubhda Roy
The document summarizes a basket trial studying the BRAF inhibitor vemurafenib in various cancers with the BRAF V600 mutation. The trial enrolled 122 patients with multiple cancer types confirmed to have the BRAF mutation. Vemurafenib showed antitumor activity in cancers with low BRAF mutation rates like non-small cell lung cancer and Erdheim-Chester disease, with overall response rates of 42% and 43% respectively. However, colorectal cancer had a poor response to vemurafenib alone or with cetuximab. While basket trials allow for studying rare cancers, they lack precision due to limited sample sizes and need further studies to develop effective targeted therapies
This document discusses colorectal cancer risk associated with family history and hereditary factors. It notes that about 3-6% of colorectal cancers are hereditary. Two major hereditary syndromes described are Familial Adenomatous Polyposis (FAP) and Hereditary Non-Polyposis Colorectal Cancer (HNPCC). For individuals with a family history of colorectal cancer, risk stratification is provided based on factors like age of relatives' diagnosis and number of affected relatives. Surveillance guidelines are outlined based on a person's family history and risk level. Taking a detailed family history is important for identifying increased risk individuals who may benefit from genetic counseling and more intensive screening.
Francesco Procaccio - Italy - Tuesday 29 - Donor Riskincucai_isodp
1. Screening donors for malignancy in the intensive care unit is important due to the increasing median age of potential donors and corresponding higher risk of undiagnosed cancers.
2. A review of literature showed that the risk of transmitting cancer through organ donation is very small when appropriate donor selection standards are followed and individual risk-benefit analysis is performed.
3. Of 146 potential donors screened at a hospital in Italy between 2007-2010, several cancers were detected including breast, prostate, liver, kidney, and blood-related cancers. Follow-up of transplant recipients showed no transmission of these cancers.
The document provides an overview of the history and development of oncology. It discusses how cancer was first documented in ancient Egypt and treated by cauterization. It then covers key developments like Hippocrates naming cancer, the first autopsy being performed in 1761, and the establishment of the TNM staging system. The summary concludes by briefly mentioning common modern cancer treatment modalities like surgery, radiation therapy, chemotherapy, and their goals of cure, palliation, or prevention.
This document summarizes a study comparing the cancer information seeking behaviors of older Vietnamese immigrants to Caucasian and African American individuals. The study found that older Vietnamese immigrants reported seeking cancer information from fewer sources and recalled information with less depth compared to other groups. Educational attainment may be a confounding factor, but many older Vietnamese refugees had low education levels upon arrival. The findings suggest efforts should increase cancer information seeking in immigrant communities to potentially improve cancer screening rates, while also increasing access to accurate, linguistically appropriate cancer information.
Kendall Phelps-Polirer has wanted to be a doctor since witnessing her friend Robin's battle with brain cancer in middle school. She participated in cancer research programs in high school and college and is passionate about joining the fight against cancer. She is deciding between becoming a medical oncologist or surgical oncologist. Both careers require extensive education and training, but will allow her to help cancer patients through treatment and support. With cancer rates continuing to rise, she is committed to pursuing a career in oncology.
Venous thromboembolism (VTE) may be the earliest sign of cancer.
Currently, there is a great diversity in practices regarding screening for occult cancer in a person who has an unprovoked VTE .
We sought to assess the efficacy of a screening strategy for occult cancer that included comprehensive computed tomography(CT) of the abdomen and pelvis in patients who had a first unprovoked VTE .
This lecture is about cervical cancer or cancer of the cervix. This malignancy is very common among women in the Philippines. Treatments may consist of radiation, surgery, chemotherapy or a combination modality. Prevention may be achieved by vaccination.
Family First: What you need to know about family history, genetic testing, a...Fight Colorectal Cancer
Have you and your family talked about the importance of knowing your family's medical history?
Did you know that 3% of all colorectal cancers are due to a syndrome called Lynch syndrome? Having Lynch syndrome puts you at an 80% increased risk of developing colorectal cancer.
This webinar will focus more about Lynch Syndrome and other inherited syndromes as they relate to colorectal cancer.
Heather Hampel, a genetics counselor from Ohio State University will discuss the importance of knowing your family history. She'll talk about when, how and where to find a genetics counselor, and what is it you should discuss with them.
This study found that younger adults (under age 40) with colon or rectal cancer that has spread to other areas have a higher risk of disease progression and death compared to middle-aged patients (ages 57-61). Younger patients were 30% more likely to die and had a 28% higher risk of the disease spreading within a year. The oldest patients (over age 61) also had a higher risk of death and disease progression compared to middle-aged patients. Further research is needed to understand why colon cancer appears more aggressive in younger adults, but genetics, environment, and decreased early detection in younger groups may play a role. Doctors need to be aware of the worse prognosis in younger patients if the cancer has spread,
Study of Endometrial Volume and Vascularity by 3D Power Doppler Ultrasound in...Crimsonpublishers-IGRWH
Study of Endometrial Volume and Vascularity by 3D Power Doppler Ultrasound in Women with Perimenopausal Bleeding by Ahmed Sherif in Investigations in Gynecology Research & Womens Health
Ulrassonagrafia de tórax em derrames pleuraisFlávia Salame
This document discusses a study that assessed the diagnostic accuracy of thoracic ultrasound (TUS) in differentiating malignant and benign pleural disease. The study involved 52 patients with suspected malignant pleural effusion who underwent both TUS and contrast-enhanced CT (CECT). TUS correctly diagnosed malignancy in 26 of 33 patients and benign disease in 19 of 19 patients, demonstrating a sensitivity of 73% and specificity of 100% for diagnosing malignant pleural disease. Pleural thickening over 1 cm, pleural nodularity, and diaphragmatic thickening over 7 mm identified on TUS were highly suggestive of malignancy. The study concludes that TUS is useful for differentiating malignant and benign pleural disease in
The document discusses the approach to evaluating ovarian masses through imaging. It describes how ovarian masses can be categorized and that epithelial tumors are the most common type of malignant ovarian tumor. The evaluation involves considering patient factors like age and mass characteristics on ultrasound like size, wall thickness, and presence of septations or solid areas. Scoring systems can help characterize masses as benign or malignant, though some remain indeterminate. MRI may help in these cases by identifying tissue types and infiltrative features suggestive of malignancy. The goal is to determine if the mass is ovarian in origin and the degree of suspicion for malignancy to guide clinical management.
Intravenozni kontrastni pregled s tehnologijo CnTIMIDEAS
1) The study aimed to determine if intravenous contrast ultrasound using contrast-tuned imaging (CnTITM) and SonoVue is superior to gray-scale or power Doppler ultrasound for differentiating benign and malignant adnexal masses.
2) 134 patients underwent standard transvaginal ultrasound followed by contrast ultrasound, and time intensity curves were analyzed.
3) Contrast signal intensity and area under the curve were significantly higher in malignant tumors compared to benign and borderline tumors, but overlap existed between benign and borderline tumors.
Prostatitis and seminal vesiculitis that is intractable , ie no effect from 4-6 weeks quinolone, with chronic symptoms of perineal discomfort, hemospermia, frequency and urgency of urination, suprapubic pain, dysuria with urethral discharge, seen by doctors and told to have chronic pelvic pain syndrome should consider to consult urologist for indications of transurethral seminal vesiculoscopy.
The document discusses several studies related to lung cancer and DNA. It summarizes that mouse models show similarities to human lung cancer, allowing scientists to study disease progression. Researchers identified a gene called NF-Iβ associated with lung cancer. A separate study found specific DNA breakage characteristics in cancer cells. This molecular-level analysis improves understanding of cancer development and susceptibility.
The document discusses several studies related to lung cancer and DNA. It summarizes that mouse models show similarities to human lung cancer, allowing scientists to study disease progression. Researchers identified a gene called NF-Iβ associated with lung cancer. A separate study found specific DNA breakage characteristics in cancer cells. This molecular-level analysis improves understanding of cancer development and susceptibility.
The document discusses several studies related to lung cancer and DNA. It summarizes that mouse models show similarities to human lung cancer, allowing scientists to study disease progression. Researchers identified a gene called NF-Iβ associated with lung cancer. A separate study found specific DNA breakage characteristics in cancer cells. This molecular-level analysis improves understanding of cancer development and susceptibility.
The document discusses two recent discoveries related to genetics and disease. Researchers discovered a mechanism of gene silencing in hormone-dependent breast cancer cells involving a protein that interacts with the progesterone receptor and compacts chromatin. Scientists also discovered an X-chromosome inherited form of brittle bone disease osteogenesis imperfecta caused by two mutations in the MBTPS2 gene on the X chromosome, making men more vulnerable. These findings provide insights that can help improve diagnosis and treatment of these diseases.
Cancer Science & Research: Open Access is a journal that covers conventional and novel cancer treatment approaches through molecular targeting, especially for rare diseases. It aims to promote worldwide cancer research efforts to understand and combat the growing problem of cancer. The journal publishes research on various topics, including diffusion weighted MRI for evaluating prostate cancer response to treatment, detecting genomic instability in renal cancer through urine samples, antioxidants from Egyptian plants for cancer treatment, and biomarkers for personalized prostate cancer imaging and radiotherapy.
MRI is more accurate than other imaging modalities for ruling out prostate cancer. While PSA testing and biopsy are currently the standard for diagnosing prostate cancer, MRI has higher specificity and can better detect the location and extent of tumors, especially in men with elevated PSA and previous negative biopsies. The addition of MRSI to MRI further improves accuracy by distinguishing cancer from surrounding tissues based on metabolic profiles. Careful patient selection is important to maximize the clinical utility of MRI and MRSI for prostate cancer diagnosis and staging.
Vemurafenib in multiple nonmelanoma cancers with braf v600 shubhda royShubhda Roy
The document summarizes a basket trial studying the BRAF inhibitor vemurafenib in various cancers with the BRAF V600 mutation. The trial enrolled 122 patients with multiple cancer types confirmed to have the BRAF mutation. Vemurafenib showed antitumor activity in cancers with low BRAF mutation rates like non-small cell lung cancer and Erdheim-Chester disease, with overall response rates of 42% and 43% respectively. However, colorectal cancer had a poor response to vemurafenib alone or with cetuximab. While basket trials allow for studying rare cancers, they lack precision due to limited sample sizes and need further studies to develop effective targeted therapies
This document discusses colorectal cancer risk associated with family history and hereditary factors. It notes that about 3-6% of colorectal cancers are hereditary. Two major hereditary syndromes described are Familial Adenomatous Polyposis (FAP) and Hereditary Non-Polyposis Colorectal Cancer (HNPCC). For individuals with a family history of colorectal cancer, risk stratification is provided based on factors like age of relatives' diagnosis and number of affected relatives. Surveillance guidelines are outlined based on a person's family history and risk level. Taking a detailed family history is important for identifying increased risk individuals who may benefit from genetic counseling and more intensive screening.
Francesco Procaccio - Italy - Tuesday 29 - Donor Riskincucai_isodp
1. Screening donors for malignancy in the intensive care unit is important due to the increasing median age of potential donors and corresponding higher risk of undiagnosed cancers.
2. A review of literature showed that the risk of transmitting cancer through organ donation is very small when appropriate donor selection standards are followed and individual risk-benefit analysis is performed.
3. Of 146 potential donors screened at a hospital in Italy between 2007-2010, several cancers were detected including breast, prostate, liver, kidney, and blood-related cancers. Follow-up of transplant recipients showed no transmission of these cancers.
The document provides an overview of the history and development of oncology. It discusses how cancer was first documented in ancient Egypt and treated by cauterization. It then covers key developments like Hippocrates naming cancer, the first autopsy being performed in 1761, and the establishment of the TNM staging system. The summary concludes by briefly mentioning common modern cancer treatment modalities like surgery, radiation therapy, chemotherapy, and their goals of cure, palliation, or prevention.
This document summarizes a study comparing the cancer information seeking behaviors of older Vietnamese immigrants to Caucasian and African American individuals. The study found that older Vietnamese immigrants reported seeking cancer information from fewer sources and recalled information with less depth compared to other groups. Educational attainment may be a confounding factor, but many older Vietnamese refugees had low education levels upon arrival. The findings suggest efforts should increase cancer information seeking in immigrant communities to potentially improve cancer screening rates, while also increasing access to accurate, linguistically appropriate cancer information.
Kendall Phelps-Polirer has wanted to be a doctor since witnessing her friend Robin's battle with brain cancer in middle school. She participated in cancer research programs in high school and college and is passionate about joining the fight against cancer. She is deciding between becoming a medical oncologist or surgical oncologist. Both careers require extensive education and training, but will allow her to help cancer patients through treatment and support. With cancer rates continuing to rise, she is committed to pursuing a career in oncology.
Venous thromboembolism (VTE) may be the earliest sign of cancer.
Currently, there is a great diversity in practices regarding screening for occult cancer in a person who has an unprovoked VTE .
We sought to assess the efficacy of a screening strategy for occult cancer that included comprehensive computed tomography(CT) of the abdomen and pelvis in patients who had a first unprovoked VTE .
This lecture is about cervical cancer or cancer of the cervix. This malignancy is very common among women in the Philippines. Treatments may consist of radiation, surgery, chemotherapy or a combination modality. Prevention may be achieved by vaccination.
Family First: What you need to know about family history, genetic testing, a...Fight Colorectal Cancer
Have you and your family talked about the importance of knowing your family's medical history?
Did you know that 3% of all colorectal cancers are due to a syndrome called Lynch syndrome? Having Lynch syndrome puts you at an 80% increased risk of developing colorectal cancer.
This webinar will focus more about Lynch Syndrome and other inherited syndromes as they relate to colorectal cancer.
Heather Hampel, a genetics counselor from Ohio State University will discuss the importance of knowing your family history. She'll talk about when, how and where to find a genetics counselor, and what is it you should discuss with them.
This study found that younger adults (under age 40) with colon or rectal cancer that has spread to other areas have a higher risk of disease progression and death compared to middle-aged patients (ages 57-61). Younger patients were 30% more likely to die and had a 28% higher risk of the disease spreading within a year. The oldest patients (over age 61) also had a higher risk of death and disease progression compared to middle-aged patients. Further research is needed to understand why colon cancer appears more aggressive in younger adults, but genetics, environment, and decreased early detection in younger groups may play a role. Doctors need to be aware of the worse prognosis in younger patients if the cancer has spread,
Study of Endometrial Volume and Vascularity by 3D Power Doppler Ultrasound in...Crimsonpublishers-IGRWH
Study of Endometrial Volume and Vascularity by 3D Power Doppler Ultrasound in Women with Perimenopausal Bleeding by Ahmed Sherif in Investigations in Gynecology Research & Womens Health
Ulrassonagrafia de tórax em derrames pleuraisFlávia Salame
This document discusses a study that assessed the diagnostic accuracy of thoracic ultrasound (TUS) in differentiating malignant and benign pleural disease. The study involved 52 patients with suspected malignant pleural effusion who underwent both TUS and contrast-enhanced CT (CECT). TUS correctly diagnosed malignancy in 26 of 33 patients and benign disease in 19 of 19 patients, demonstrating a sensitivity of 73% and specificity of 100% for diagnosing malignant pleural disease. Pleural thickening over 1 cm, pleural nodularity, and diaphragmatic thickening over 7 mm identified on TUS were highly suggestive of malignancy. The study concludes that TUS is useful for differentiating malignant and benign pleural disease in
The document discusses the approach to evaluating ovarian masses through imaging. It describes how ovarian masses can be categorized and that epithelial tumors are the most common type of malignant ovarian tumor. The evaluation involves considering patient factors like age and mass characteristics on ultrasound like size, wall thickness, and presence of septations or solid areas. Scoring systems can help characterize masses as benign or malignant, though some remain indeterminate. MRI may help in these cases by identifying tissue types and infiltrative features suggestive of malignancy. The goal is to determine if the mass is ovarian in origin and the degree of suspicion for malignancy to guide clinical management.
Intravenozni kontrastni pregled s tehnologijo CnTIMIDEAS
1) The study aimed to determine if intravenous contrast ultrasound using contrast-tuned imaging (CnTITM) and SonoVue is superior to gray-scale or power Doppler ultrasound for differentiating benign and malignant adnexal masses.
2) 134 patients underwent standard transvaginal ultrasound followed by contrast ultrasound, and time intensity curves were analyzed.
3) Contrast signal intensity and area under the curve were significantly higher in malignant tumors compared to benign and borderline tumors, but overlap existed between benign and borderline tumors.
Prostatitis and seminal vesiculitis that is intractable , ie no effect from 4-6 weeks quinolone, with chronic symptoms of perineal discomfort, hemospermia, frequency and urgency of urination, suprapubic pain, dysuria with urethral discharge, seen by doctors and told to have chronic pelvic pain syndrome should consider to consult urologist for indications of transurethral seminal vesiculoscopy.
This document discusses several studies on urological injuries and conditions:
1. A study of 25 female patients with urethral and bladder neck injuries from pelvic fractures, finding many required surgical repair and long-term urinary and sexual dysfunction for some.
2. A study of 8 girls with pelvic fracture urethral strictures, finding 1-stage repair and substitution urethroplasty had 100% success rates and advocating early cystostomy drainage and deferred reconstruction when needed.
3. An editorial comment on female urethral injuries from pelvic fractures, noting they require high suspicion to diagnose and advocating early repair of urethral and vaginal injuries to
Evaluation of Obstructive Uropathy with Computed Tomography Urography and Mag...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Radiological Findings in Infertile Men in a Fertility Centre in Jos, Nigeria.QUESTJOURNAL
ABSTRACT:Infertility is a great psychological burden to the infertile couple. Scrotal ultrasonography and colour Doppler imaging of the scrotum are useful adjuncts to clinical examination in assessing intratesticular and extratesticular abnormalities. Methodology:All men who presented with infertility were evaluated. These included comprehensive history, physical examination and investigation, in this case seminal fluid analysis and scrotal ultrasonography. Results:This was prospective study carried out at the Jos University Teaching Hospital and a fertility centre in Jos from 2012 to 2017. A total of 67 men were involved in this study. The mean age was 39.39yrs. Age range was 28 to 59yrs. Sixty three (N=63) of the men had abnormal semen parameters representing 94.03% while four men (N=4) had normal semen parameters. Thirty eight patients representing 56.72% had azoospermia while 5.97% had normozoospermia following seminal fluid analysis. The mean volume of the right testis was 11.93ml. The range was 2.9ml to 25ml. The mean volume of the left testis was 11.76ml. The range was 2.9ml to 22ml. Overall mean testicular volume was 11.85ml. Forty two men (N=42) had abnormalities on scrotal ultrasound representing 62.69%. Abnormalities on ultrasonographyinclude varicocele33%, cryptorchidism31%, hydrocele 17%, testicularmicrolithiasis7%, multiple complex testicular cyst5%, epididymal cyst5% and echogenic testis2%. Conclusion:Scrotal ultrasonography is important in the assessment of testicular volume and abnormalities such as varicocele, cryptorchidism and hydrocele which affects male fertility.
EIS Technology: bioimpedance chronoamperometry in adjunct to screen the prost...ES-Teck India
Through the 6 tactile electrodes, a weak DC current is sending alternatively between 2 electrodes with a sequence and the EIS system is recording the electrical conductance of 11 pathways of the human body.
Doppler determinants in ovarian tumorsAkshay Dhina
This document summarizes a study on using Doppler ultrasound to differentiate between benign and malignant ovarian tumors. The study found that using color Doppler and spectral Doppler analysis improved sensitivity from 53% to 82% and specificity from 83% to 94%, compared to ultrasound alone. Key findings included:
- 92% of malignant tumors showed neovascularization compared to 42% of benign tumors.
- An resistive index of <0.6 and peak systolic velocity index of <0.8 occurred in 92% of malignant versus 6.4% of benign tumors.
- Location of blood flow (central vs. peripheral) helped differentiate solid benign and malignant tumors.
The study concluded Doppler ultrasound provides important additional information over ultrasound alone
In this presentation we will discuss about the
Anatomy of Prostate
Technique of Transrectal US
Carcinoma Prostate and
Different modes of prostatic biopsy.
This study analyzed 94 pre-implantation kidney biopsies from living donors to detect any histological abnormalities. Some key findings included segmental glomerular sclerosis in 9.6% of biopsies, mesangial thickening in 29.8%, global sclerosis in 29.8%, and tubular atrophy in 7.4%. No interstitial fibrosis was found. The study aims to evaluate the usefulness of these biopsies for clinical and research purposes and to compare the baseline biopsy findings with subsequent allograft biopsies. The conclusion is that pre-implantation biopsies can detect histopathological abnormalities and provide clinically useful information to serve as a reference for future pathology.
This study aimed to use karyometry to detect nuclear abnormalities in fallopian tube epithelium from women at high risk for ovarian cancer compared to low risk women. Karyometry involves high-resolution imaging and quantitative analysis of nuclear features too small to be seen by the human eye. The study found distinct deviations in nuclear features and signatures in fallopian tubes from high risk women carrying BRCA1/2 alterations compared to normal risk women. Specifically, measures of pixel optical density heterogeneity and very dark stained pixels showed a statistically significant shift, identifying an abnormal morphometric phenotype in high risk women. The results suggest karyometry may help detect early changes and improve ovarian cancer screening.
EVALUATION OF MALE URETHRAL STRICTURES USING SONOURETHROGRAPH...Sekhar reddy MD Radio
Sonourethrography is a non-invasive imaging technique that uses ultrasound to evaluate male urethral strictures. This study aims to compare the efficacy of sonourethrography to the current gold standard, retrograde urethrography, in assessing urethral strictures. 40 male patients with strictures will undergo both sonourethrography and retrograde urethrography. Variables such as stricture morphology, length and periurethral findings will be measured and compared between the two techniques. Statistical analysis will evaluate the sensitivity, specificity and agreement between the methods. This study hypothesizes that sonourethrography is an effective alternative to retrograde ure
Trial randomizzato di screening del cancro della prostata: 20 anni di follow-upMerqurioEditore_redazione
This 20-year randomized controlled trial assessed whether screening for prostate cancer reduces mortality. It found:
1) 85 cases of prostate cancer were diagnosed through screening vs 292 cases in the control group.
2) The risk ratio for death from prostate cancer was 1.16, not a statistically significant difference.
3) After adjusting for age, the hazard ratio was 1.58, a statistically significant difference, suggesting screening may reduce mortality. However, the absolute reduction in mortality was small.
Radiological Findings in ScrotalFilariasis - A Case SeriesPrakhar Varshney
Filariasis is prevalent in Bihar, UP, Andhra Pradesh, Jharkhand and is noted through the tropical and sub-tropical region. There are approximately 31 million people infected in India and approximately half of them do not show the clinical manifestations of this disease.
Filariasis mainly involves the lymphatic system of the body.
The most frequently involved parts of the lymphatic system are the lower limbs, retroperitoneal tissues, spermatic cord, epididymis and mammary glands.
This study examined the association between darkening of third molar roots seen on preoperative panoramic radiographs and exposure of the inferior alveolar nerve during surgery. 116 patients with darkening of third molar roots were selected as the case group, and 193 patients with other high-risk radiographic signs near the roots were selected as the control group. The nerve was exposed in 27.6% of cases with isolated darkening and 7.8% of controls. Darkening alone or with other signs significantly increased the risk of nerve exposure compared to other signs alone. Having both darkening and other adjacent signs carried the greatest risk of exposure compared to darkening alone or other signs alone or combined. Differentiating between isolated dark
This study examined the association between darkening of third molar roots seen on preoperative panoramic radiographs and exposure of the inferior alveolar nerve during surgery. 116 patients with darkening of third molar roots were selected as the case group, and 193 patients with other high-risk radiographic signs near the roots were selected as the control group. The nerve was exposed in 27.6% of cases with isolated darkening and 7.8% of controls. Darkening alone or with other signs significantly increased the risk of nerve exposure compared to other signs alone. The risk was greatest for darkening accompanied by other adjacent signs, with an odds ratio over 5 times higher than for other signs alone. This suggests differentiating
Journal of the Formosan Medical Association (2011) 110, 695e70.docxcroysierkathey
Journal of the Formosan Medical Association (2011) 110, 695e700
Available online at www.sciencedirect.com
journal homepage: www.jfma-online.com
ORIGINAL ARTICLE
A multivariable logistic regression equation to
evaluate prostate cancer
Jhih-Cheng Wang a, Steven K. Huan a, Jinn-Rung Kuo b, Chin-Li Lu c,
Hung Lin a, Kun-Hung Shen a,*
a Division of Urology, Departments of Surgery, Chi-Mei Medical Center, Tainan, Taiwan
b Division of Neurosurgery, Department of Surgery, Chi-Mei Medical Center, Tainan, Taiwan
c Department of Medical Research, Chi-Mei Medical Center, Tainan, Taiwan
Received 29 January 2010; received in revised form 14 May 2010; accepted 9 August 2010
KEYWORDS
Logistic regression;
men’s health;
probability;
prostate cancer;
risk factor;
score
* Corresponding author. Division of U
Taiwan 710.
E-mail address: [email protected]
0929-6646/$ - see front matter Copyr
doi:10.1016/j.jfma.2011.09.005
Background/Purpose: A possible means of decreasing prostate cancer mortality is through
improved early detection. We attempted to create an equation to predict the likelihood of
having prostate cancer.
Methods: Between January 2005 and May 2008, patients who received prostate biopsies were
retrospective evaluated. The relationship between the possibility of prostate cancer and the
following variables were evaluated: age; serum prostate specific antigen (PSA) level, prostate
volume, numbers of prostatic biopsies, digital rectal examination (DRE) findings, and the pres-
ence of hypoechoic nodule under transrectal ultrasonography.
Results: A multivariate regression model was created to predict the possibility of having pros-
tate cancer, and a receiver-operating characteristic (ROC) curve was drawn based on the
predictive scoring equation. Using a predictive equation, P Z 1/(1 � e�x), where X Z
�4.88, þ 1.11 (if DRE positive), þ 0.75 (if hypoechoic nodule of prostate present), þ 1.27
(when 7 < PSA � 10), þ 2.02 (when 10 < PSA � 24), þ 2.28 (when 24 < PSA � 50), þ 3.93 (when
50 < PSA), þ 1.23 (when 65 < age � 75), þ 1.66 (when 75 < age), followed by ROC curve
analysis, we showed that the sensitivity was 88.5% and specificity was 79.1% in predicting
the possibility of prostate cancer.
Conclusion: Clinicians can tailor each patient’s follow-up according to the nomogram based on
this equation to increase the efficacy of evaluating for prostate cancer.
Copyright ª 2011, Elsevier Taiwan LLC & Formosan Medical Association. All rights reserved.
rology, Department of Surgery, Chi-Mei Medical Center, 901 Chung Hwa Road, Yung Kang City, Tainan,
il.com (K.-H. Shen).
ight ª 2011, Elsevier Taiwan LLC & Formosan Medical Association. All rights reserved.
mailto:[email protected]
http://dx.doi.org/10.1016/j.jfma.2011.09.005
www.sciencedirect.com/science/journal/09296646
http://www.jfma-online.com
http://dx.doi.org/10.1016/j.jfma.2011.09.005
http://dx.doi.org/10.1016/j.jfma.2011.09.005
696 J.-C. Wang et al.
Prostate cancer is the most common solid malignancy ...
Fine needle aspiration cytology (FNAC) is a simple and rapid diagnostic procedure to identify an etiology in an enlarged lymph node. The procedure is quite effective in diagnosing malignancies in superficial lymph nodes.
Aim: To evaluate the role of FNAC as a first line investigation to identify malignancies in superfi cial lymph nodes.
Similar to Prevalence of Cystic Paraurethral Structures in Asymptomatic Women at Endovaginal and Perineal Sonography. (20)
The document discusses plans to establish a uro-gynecology and pelvic floor disorders center at Al Zahra Hospital in Dubai. It outlines that currently there are no dedicated uro-gynecology centers or subspecialist consultants in the UAE. The proposed center would be led by a dual-accredited uro-gynecology consultant and would provide specialized clinics and treatments for a wide range of conditions using evidence-based care pathways. It would establish the gold standard for care of conditions like incontinence and prolapse across the UAE. The center aims to set up robust governance, education, and data collection to help more women.
The Al Zahra Hospital Urogynecology & Pelvic Floor Disorders UnitMichelle Fynes
Dr. Michelle Fynes set-up the first UAE based Uro-Gynecology and Pelvic Floor Disorders center at the Al Zahra Hospital Dubai from 11/2018. This service provides a General Uro-Gynecology and Pelvic Floor Disorders clinic for females of all ages, a specialist clinic for women with childbirth injury and/or pregnancy related continence disorders, and a Paediatric Adolescent Gynecology clinic.
Endometrial hyperplasia is an abnormal overgrowth of the endometrial lining that can progress to cancer if left untreated. It is classified as either without atypia or with atypia based on presence of cell abnormalities. Treatment involves identifying risk factors like obesity and treating with progestogen therapy. For hyperplasia without atypia, the levonorgestrel IUD is first-line treatment for 6 months followed by surveillance. Hysterectomy may be considered if treatment fails or for atypical hyperplasia. Close monitoring is important to detect progression or recurrence of the condition.
The objectives of this report includes, introducing and looking at the overview of the topic of PCOS, the history of PCOS and what have we learnt about PCOS 1970-2018 etc.
Benign Disorders of the Vulva: Pruritus (itchy) Vulva Vulval Skin and Pain Di...Michelle Fynes
Vulval skin disorders are not common and may be asymptomatic or present with pruritus (itching), skin changes, discomfort or pain including dyspareunia.
Uterine Fibroids (Leiomyomata): Investigations and Treatment Michelle Fynes
Uterine fibroids (UF) are the most common benign neoplastic threat to women's health, costing hundreds of billions of health care dollars worldwide. The objective of this presentation is to review risk factors, aetiology, classification and clinical presentation of Uterine fibroids.
Vesicouterine Fistula Following Cesarean Delivery – Ultrasound Diagnosis and ...Michelle Fynes
Vesicouterine fistulae are uncommon, with most units reporting 1–5 cases over 5–15 year periods. To date there has been a paucity of case reports regarding this problem and only a few case series. In this report we outline the presentation and management of a vesicouterine fistula complicating a repeat Cesarean delivery, specifically describing the role of transvaginal ultrasound.
Overview normal physiological development; skeletal growth, maturation of the reproductive tract, development secondary sexual characteristics, CNS maturation, personality and psychology of the female adolescent.
Gynaecology - Early Pregnancy ComplicationMichelle Fynes
What to expect during the course of her care (including expectant management), such as the potential length and extent of pain and/or bleeding, and possible side effects. This information should be tailored to the care she receives.
Female Genital Cosmetic Surgery (FGCS) ‘enhancement’ or ‘mutilation’? Michelle Fynes
Decisions to alter genitalia may be based on misguided assumptions of normal dimensions. Recent report dimensions of female genitals (50 premenopausal women).
Assessment and management of anterior vaginal wall defects presents a unique surgical challenge and is the most common site of initial prolapse in women and the most common site of recurrence.
Laparoscopic surgery is generally safer and preferred over laparotomy for managing ovarian cysts in pre-menopausal women when possible. For asymptomatic simple cysts under 5cm, observation is usually sufficient as most will resolve on their own within a few cycles. Cysts over 5cm or those causing symptoms may require surgery. Laparoscopy has benefits over laparotomy like less pain, faster recovery, and shorter hospital stay. Emergency situations like cyst torsion require prompt surgical intervention. In pregnancy, asymptomatic cysts under 6cm can often be observed, while symptomatic cysts may require laparoscopic removal which appears to carry low risk to mother and baby.
Uro-Gynaecology (UG): Sub-speciality of gynaecology dealing with benign disorders of the lower urinary and genital tract, mainly urinary incontinence and genital prolapse.
The Prognostic Value of Nucleolar Organiser Regions in Colorectal CancerMichelle Fynes
Nucleolar organiser regions (AgNORs) are loops of ribosomal DNA which reflect the cellular activity or malignant potential of the cell and are identified by a specific staining technique. The purpose of this study was to assess the prognostic value of AgNORs in colorectal cancer and to compare it with other accepted prognostic methods.
Information For You After a Pelvic Floor Repair OperationMichelle Fynes
This document provides information for women recovering after a pelvic floor repair operation. It details what patients can expect in terms of usual hospital stay length, common after-effects like pain and bleeding, and advice on activities like exercise, diet, and returning to normal activities. The document emphasizes the importance of rest, pelvic floor exercises, mobility, and following an enhanced recovery program to aid in healing and returning to full health as quickly as possible after surgery.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
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Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
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Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
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Prevalence of Cystic Paraurethral Structures in Asymptomatic Women at Endovaginal and Perineal Sonography.
1. 6/4/2018 Prevalence of cystic paraurethral structures in asymptomatic women at endovaginal and perineal sonography. - PubMed - NCBI
https://www.ncbi.nlm.nih.gov/pubmed/11446756 1/1
AIM:
PATIENTS AND METHODS:
RESULTS:
CONCLUSION:
Clin Radiol. 2001 Jul;56(7):575-8.
Prevalence of cystic paraurethral structures in asymptomatic
women at endovaginal and perineal sonography.
Cross JJ , Fynes M, Berman L, Perera D.
Abstract
To prospectively assess the prevalence of paraurethral cystic structures in asymptomatic
adult women.
One hundred and forty consecutive women undergoing endovaginal
sonography with no history of lower urinary tract symptoms.
Paraurethral cystic structures were identified in 4/140 subjects (2.9%). Ultrasound
assessment allowed rapid definition of the site, size and vascularity of these lesions and was well
tolerated by the patient.
This is the first prospective ultrasound study to determine the prevalence of
paraurethral cystic structures in a large consecutive cohort of asymptomatic women. Our findings
are in accordance with previously published post-mortem data and surgical series which have
estimated the prevalence of paraurethral cystic structures to be between 1 and 6%.
PMID: 11446756 DOI: 10.1053/crad.2000.0709
[Indexed for MEDLINE]
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