The document discusses acid reflux and the role of dietary acid in exacerbating symptoms. It notes that 100 million Americans have reflux but many are unaware or misdiagnosed. While acid is problematic, the digestive enzyme pepsin is the main cause of tissue damage. Pepsin remains active over a wide pH range and dietary acid can reactivate pepsin already in tissues, preventing healing. A strict low-acid diet is recommended to reduce symptoms and reverse damage from reflux. Clinical trials showed significant improvement in 95% of patients with recalcitrant laryngopharyngeal reflux following an induction diet. The increasing prevalence of esophageal cancer is linked to rising consumption of acidic foods.