a example for poster presentation

1. A REVIEW ON COCAIN ABUSE
Saginela Sailaja*, K.Karthik
Pharma D 4th year,
Jagans collage of pharmacy, Nellore.
Saginelasailaja@gmail.com
INTRODUCTION:
 Cocaine is an alkoloid obtained from the leaves of coca tree, and is a
powerful addictive CNS stimulant.
 FEATURES:
 Family: Erythroxylum coca.
 Category: Shrubs, Fruits.
 It’s chemical name is Methylbenzoylecogonine, that is active principle obtained from the coca leaves.
NEED FOR THE STUDY:
Now-a-days the percentage of young aged people are extended to great addiction .
The drug abuse is more especially in United states when compared with in India .
So , The need of study on this title to get the info behind the cocaine drug along with
perceive percentage of drug abuse in India as per the statistical studies.
Abstract No: 44

2. AVAILABLE DOSAGE FORMS:
 Water soluble Hydrolytic salt form
 Freebase
 Crack
ROUTE OF ADMINISTRATION:
There are different types such as:
 Intravenous
 Ingestion: Both cocaine and leaves of coca plant
 Snorting
 Smoking.

3. HOW DOES COCAIN EFFECTS IN THE BRAIN
 In normal communication process, dopamine is released by
a neuron into the synapse, where it can binds to dopamine
receptors on neighboring neurons. Normally, dopamine is
recycled back into the transmitting neuron. By a specialized
protein called as dopamine transporters.
 If cocaine is present ,it attaches to dopamine transporters
and blocks the normal recycling process. resulting in a build up
of dopamine in the synapse.

4. SHORT TERM AND LONG TERRM EFFECTS OF COCAIN USE

5. STATISTICAL ANALYSIS:

6. DISCUSSION:
On the basis of statistical study of cocaine use in India is 0.11%.
 When compared with other drugs along the different countries.
But, the opioids use in India higher than global average.
While frequently taking this drug cocaine overdose may results to drug
 addiction.
And it can causes the physical effects, psycological effects at low doses.
At increased doses, also results of physical effects; seizures,
 cardiac arrest, myocardiac infection, stroke, respiratory arrest.
Psychological effects like Anxiety, irritability, insomnia, depression,
 paranoid and may also exhibits over system effects

7. SUMMARY:
Cocaine is a white powder
It can be snorted nose/mixed with water and injected with a needle
Cocaine speed up your whole body, you may feel full of energy,
happy and excited. But then your mood can changes.
Some of the
most common serious problems includes : Heart attacks, Stroke.
You may risk for HIV/AIDs and Hepatitis, from sharing needles or
having sex..
Cocaine is a more dangerous when combined with other drugs or alcohol.
It is easy to loss control over cocaine use and become addicted.
Then, even if you get treatment, it can be hard to stay off the drug.

8. ASSESMENT:
• Compression assessment: Medical, psychiatric, psychosocial.
• Abstinence initiation: Readiness for change.
• Relapse prevention: Different level of care, Inpatient, IOP, Outpatient.
TREATMENT: Pharmacological treatment

9. CONCLUSION:
 The use of cocaine drug it for valid medical purpose like local anaesthesia, some surgeries includes eye, ear and
tongue etc, But now a days the young agers are more addicted (drug abuse) to this Drugs as per statistical analysis.
 But if you prolong/frequents introducing of these drug may resultants of drug addiction.
That is forced by all age grouped of the society.
 Drug addiction should be stopped at an immediate effect to avoid further loss of
the present generation and reduce the negative impact on the upcoming generation.
 The more drug abuse can be seen in United State.

10. ACKNOWLEDGMENT:
We are Thankful to SEVEN HILLS COLLEGE OF PHARMACY ,TIRUPATHI for providing required
facilities to accomplish the POSTER PRESENTATION of the above entitled work.
REFERENCE:
1. Calatayud J, Jonzalez A. History of the development and evolution of Local Anesthesia since the coca
leaves. Anesthesiology.
2003;98(6):1503-1508
2. Https://WWW.slideshare,net/Jayesh dabhi/cocain-56281600.
3. Baik J-H. Dopamine signalling in reward-related behaviours. Front neural circuits.2013;7. doi:10.3389/fncir
2013.001
4. https://www.unodc.org/documents/data-and-analysis/cocaine/Cocaine-Insights-2021 .pdf
5. https://s://nida.gov/download/1141/cocaine-reseach-report.pdf
6. Buch S, Yao H, Guo M, et al. Cocain and HIV 1 interplay in CNS: cellular and molecular mechanisms Curr
HIV Res. 2012;10(5):425-428.
7. https://www.researchgate.net/publication/272415259-cocaine
8. K.D Tripati and Rang & Dale’S Pharamcology.