The document discusses various issues around genetic engineering and who should decide on its limits. It summarizes that twin studies do not necessarily show the importance of genetics in traits, and most genetic association studies are inconsistent. It then outlines several current controversies, including gene tests and DNA databases which could enable surveillance and discrimination. Other controversies include hybrid embryos, cloned embryos, GM animals and crops. The document calls for debate on the assumptions behind genetic explanations and solutions, and who should decide research priorities and applications in the public interest.