The document provides tips for developing self-mastery through establishing daily habits and routines. Some key recommendations include setting aside one hour each morning for personal development activities like meditation, reading inspirational texts, and listening to motivational materials. It also suggests laughing for five minutes in the mirror each day, spending Sundays with family, walking after dinner, fasting one day every two weeks, reading books regularly, and developing habits of optimism, punctuality, and serving others. The overall message is that establishing beneficial daily practices and disciplines can help one achieve higher levels of success, focus, health and well-being.
I too am a TEENAGER Born To Excel. Excel, I will ! Book for teens by C F JosephSree Raj
This book is dedicated to all the teenagers in the world. You were Born To Excel. May you have the capability, strength and discipline to live your life from the inside out, and may you maintain a firm belief in yourself and in others with whom you come in contact. You are the author of your future; may you live the life of your dreams.
I too am a TEENAGER Born To Excel. Excel, I will ! Book for teens by C F JosephSree Raj
This book is dedicated to all the teenagers in the world. You were Born To Excel. May you have the capability, strength and discipline to live your life from the inside out, and may you maintain a firm belief in yourself and in others with whom you come in contact. You are the author of your future; may you live the life of your dreams.
All I ask is that you take your time reading this book, take it all in at your own pace, and try not to get overwhelmed, as there are several ways you can do things when it comes to living a life with holistic wellness. There is no right or wrong way to think about what you feel you are most comfortable doing.
This is something I felt the need to share because of the times we are currently living in. Now being in my early sixties, and given time to reflect, I believe it will be helpful to the world.
All that’s left now is for you to go through this guide and decide what path you want to take, then give it a go!
My sincere prayer is that you will find this information helpful in giving you some clarity and an enlightening purpose for your life that will be beneficial to not only you, but your family and community as well.
Take 15 - 45 minutes to brain dump everything you can think of on a blank sheet of paper.
This is where you can first start to utilize the benefits of writing in your journal. Your journal is your private place to write down your thoughts to help organize your life, clear your head, and prioritize your thoughts and plan your life, before you go to your planner to schedule your day accordingly.
In particular, writing what you may have just dreamed about the night before. Start your day with the focus of an eagle by writing out everything that’s in your heart and mind.
Because we’re so busy with everything in life as a whole, we can get overwhelmed and stressed out. Brain dumping will help out greatly in this regard.
Because brain dumping clears your mind. Recording all of your thoughts and feelings someplace else allows you to get it out of your head, to stop thinking about it. The entire process also helps you determine which thoughts, feelings, and ideas are important and which ones you can let go of.
“Mental health” refers to your overall psychological well-being. It includes the way you feel about yourself, the quality of your relationships, and your ability to manage your feelings and deal with difficulties.
Anyone can experience mental or emotional health problems — and over a lifetime, many of us will. I believe I read somewhere that one in five adults in the western world live with mental health or substance abuse problems.
Even if that is not precisely so, we can all agree that there are too many people who unfortunately experience these difficulties.
Here are 10 tips that can help you elevate your mood, become more resilient, and enjoy life more: make social connections; stay active; talk to someone; appeal to your senses; take up a relaxation practice; make leisure and contemplation a priority; talk to someone; Eat a brain-healthy diet to support strong mental health; don’t skimp on sleep; find purpose and meaning for your life; and get help if you need it.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
2. Sleep less: This is one of the best investment you can make to make your life more productive and rewarding
3. Set aside one hour every morning for personal development matters. Meditate, visualize your day, read inspirational texts to set the tone of your day, listen to motivational tapes or read great literature. Starting the day off well is a powerful strategy for self renewal .
4. Laugh for five minutes in the mirror each morning. Laughter activates many beneficial chemicals within the body that place us into a very joyous state. Laughter also returns the body to a state of balance. A 4 year old laughs 500 times a day while the average adult is lucky to laugh 15 times a day.
5. Set aside every Sunday evening for yourself and your family and be strongly disciplined with this habit.
6. To enhance your concentration and power of focus, count your steps when you walk. This is a particularly strong technique. so many people allow their minds to be filled with mental chatter. All peak performers appreciate the power of a quiet clear mind which will concentrate steadily on all important tasks.
7. Enhance your will-power. You must first exercise it and then push before it gets stronger. When you are hungry, wait another hour before your meal. When you are labouring over a difficult task and your mind is prompting you to pick up the latest magazine for a break , curb the impulse. Soon you will be able to sit for hours in a precisely concentrated state. Newton had a remarkable ability to sit quietly and think without interruption for a very long period of time. If he can develop this so can you.
8. Never discuss your health, wealth and other personal matters with anyone outside your immediate family. Be very disciplined in this regard.
9. Cultivate the art of walking half an hour after your dinner. Walks in natural settings are the very best. Walking is, perhaps, nature’s ideal exercise.
10. Be careful about your reputation. Never do anything you wouldn’t be proud to tell your mother about. Have fun always but temper it with common sense and prudence.
11. Become your spouse”s number one supporter, the one who is always there supporting and fueling hopes and dreams. Develop together and march confidently through the world as an army of two.
12. Spend time with Nature. Natural settings have a powerful effect on your senses which in turn will lead to a sense of renewal, refreshment and peacefulness.
13. Try fasting one day every two weeks. During these fast days, drink fruit juice and eat fresh fruits only. You will feel more energetic, cleansed and alert.
14. Drown your appetite by drinking more water – ten glasses a day is ideal. It revitalizes the system and purifies the body. Also get into the habit of eating soups and more complex carbohydrates such as rise, potatoes than other less healthy foods.
15. A contented mind is a continual feast. Greed and material desires must be curbed to achieve lasting happiness and serenity. Be happy with what you have.
16. Every day, get away from the noise, the crowds and the rush and spend a few hours alone in peaceful introspection, deep reading or simple relaxation.
17. Empty your cup. A full cup cannot accept anything more. Similarly, a person who believes that he cannot learn anything else will stagnate quickly and not move to higher levels. Even the teachers have teachers.
18. Drink a cup of warm water before a speech. Ronald Reagan Employed this strategy to ensure that he maintained his honey-smooth voice. You will be judged by the calibre of your communication skills.
19. Always remember the key principle that the quality of your life Is the quality of your communication. This means the way you Communicate with others and more, importantly with yourself. What you focus on is what you get.
20. Aromas have been proven to be an effective means of entering a state of relaxation. Scents have a very noticeable effect on your mindset and moods.
21. Never argue with the person you work for – you will lose more than just the argument
22. Do not take personal development books as gospel. Read them and take whatever useful ideas you need. Some people fee they must do everything suggested and take the techniques to extremes. Every book has at least one tool or strategy of benefit.
23. Keep well-informed about current events, the latest books and popular trends. Many peak performers read five or six papers a day. You don’t have to read every story of every paper. Know what to focus on.
24. Readers are leaders. US Ex President Bill Clinton read more than 300 books during his short time at Oxford Universitgy. Some top performers read a book a day. The more you know, the less you fear.
25. When you cannot make up your mind which of two evenly balanced courses of action you should take-choose the bolder,said WJ.Slim. Take chances, take smart risks and you will meet with success beyond your dreams.
26. You sow an action, you reap a habit. You sow a habit, you reap a character. You sow a character, you reap a destiny. The essence of a person is his character- make yours unique, unblemished and strong. Do not say you will do anything unless you will indeed do it. Speak the truth and measure your words wisely. Be humble, straight forward and peaceful.
27. Read the biographies of the world’s leaders and learn from their habits, inspirations and philosophies. Cultivate the important practice of active role modelling.
28. Remember and use people’s names when you talk to them. A person’s name is a uniquely sweet sound to them.
29. Go outdoors and look up into the blue sky for half an hour. Note the supremely strong feeling that you get when y ou are connected to Nature. Get away from your rigid schedule which will provide a refreshing release and make you feel wonderful when you eventually return.
32. Develop the essential habit of punctuality for it is most important for high success. Punctuality reflects discipline and proper regard for others. Without it, even the most sophisticated person appears slightly offensive.
33. Winners do the things that less developed people don’t like doing even though they also might not enjoy doing them. This is what strength of character and courage is all about.
34. All individuals who have attained the highest of levels generally have cultivated the essential mental habit of optimism. Without optimism, life loses its lustre and hardships appear at every step.
35.
36. Each day, do two things that you do not like doing. This may be the preparation of a report you have been putting off or shining your shoes. It does not matter how small the task, just do it! Your personal power will increase and your productivity will soar.
37. Pick five relationships that you desire to improve over the next six months. Write out the names of these people and under each name detail why you want to improve the relationship, how you plan to do so and in what time frame. This is simply another facet of goal setting.
38. Browse second-hand bookstores every few months searching for lost treasures of character-building books. You will find gems on public speaking, improving your habits, time management, personal health and other important subjects for low prices.
39. Be known as someone with a cool head, warm heart and great character. Your presence on this earth will long be remembered.
40. Fill your home with bright, fresh flowers. This is one of the best investments you can make. Let the sounds of great music, loud laughter and good fun fill the oasis of your home
41. Recognize the power of mantras and the repetition of positive, powerful words. Indian yogis have employed this technique for over 4000 years to live tranquil, productive and focused lives.