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Exercise Intensity Impacts Short-Term Memory
Allison Bader, Victoria Casani, Elizabeth Gillett, Christina Machado, and Dr. Usha Sankar
Human Physiology BISC 3132, Fordham University, Bronx, NY
	
  
Background:
As we age,	
  the size of our hippocampus, which controls
memory and learning, shrinks. Studies have found that
exercise negated the natural shrinking of the hippocampus,
therefore protecting the individual from short-term memory
loss (Alves, 2011). This has been demonstrated in studies of
gerbils, where exercise was shown to suppress ischemia-
induced apoptotic neuronal cell death in the denate gyrus of
the hippocampus (Kim et al. 2004). Although exercise of
any kind is found to have a positive affect on short-term
memory, research points to a link between the intensity of
aerobic exercise and its effects on short-term memory (Ellis
et al. 1986). In addition, initial fitness level and age are
significant factors that affect memory improvement
(Blumenthal et al. 1988). Exercise has been shown to
initiate growth factor cascades which affect structural and
functional changes in the hippocampus, particularly
increasing synaptic plasticity (Berchtold et al. 2007). If
exercise intensity or duration increases, the debilitating
effects of muscular fatigue may cancel the facilitative
effects of exercise. An optimal level of aerobic exercise will
increase blood circulation, nutrient delivery, and oxygen
delivery to the brain, creating greater neural plasticity and
enlargement of the hippocampus, a better cognitive
performance, and an improved short-term memory.
Aims:
This study aims to investigate the impact of exercise on short-
term memory by using memory tests from the Memory
Assessment Scales.
Data Results:
Scores will be tabulated for each of the tests, and statistical
significance calculations will be made. Numerous
comparisons can then be made, such as between
(1)  the pre-exercise state and the post-exercise state between
age groups
(2)  the pre-exercise state and the post-exercise state within
an age group
(3)  the pre-exercise state and the post-exercise state between
the control and the experimental groups,
(4)  between the post-high intensity and post-low intensity
exercise within an age group,
(5)  between the post-high intensity and post-low intensity
exercise between age groups, and
(6)  between the post-high intensity and post-low intensity
exercise between the control and experimental groups.
Experiment:
This experiment will utilize memory tests from the
Memory Assessment Scales developed between 1981-1990.
Each group will be asked to complete the tests under 3
conditions: (1) while seated and relaxed prior to exercise,
(2) after exercising at 75-80% intensity for 20 minutes, and
(3) after exercising at 40-45% intensity for 20 minutes.
The following short-term memory tests will be utilized:
1. List Learning.
2. Visual Span.
3. Names-Faces.
Hypothesis:
Individuals who exercise have better short- term memory
capabilities than those who do not.	
  
Methods:
Each person in this study will be assessed for pre-
existing conditions that may interfere with their ability
to perform strenuous exercise. 3 groups of people will
be used:
1. 50 people (25 female and 25 male) between ages
18-25 who do not exercise regularly.
2. 50 people (25 female and 25 male) between ages
45-55 who do not exercise regularly.
3. 50 people (25 female and 25 male) who exercise
regularly (3-5 times per week). This group is the
control.
Literature Cited:
Alves, Heloisa, Chandramallika Basak, Laura Chaddock, Kirk I. Erickson, Susie Heo, Jennifer S. Kim, Arthur F. Kramer, Stephen A. Martin, Edward McAuley, Brandt D. Pence, Ruchika Shaurya Prakash, Amanda Szabo,
Victoria J. Vieira, Michelle W. Voss, Jeffrey A. Woods. “Exercise Training Increases Size of Hippocampus and Improves Memory.” Proceedings of the National Academy of Sciences. Vol. 108. February 2011. 3017-3022.
Berchtold, Nicole C., Lori-Ann Christie, and Carl W. Cotman. “Exercise Builds Brain Health: Key Role of Growth Factor Cascades and Inflammation.” Trends in Neuroscience. Vol. 30 (9). Sept 2007. 464-472.
Blumenthal, James A. and David J. Madden. “Effects of Aerobic Exercise Training, Age, and Physical Fitness on Memory-Search Performance.” Psychology and Aging. Vol. 3 (3). Sept 1988. 280-285. Ellis, Norman R. and Phillip D. Tomporowski. “Effects of Exercise on Cognitive Processes: A
Review.” Psychological Bulletin. Vol. 99 (3). May 1986. 338-346.
Kim, Chang-Ju, Jee-Youn Kim, Sung-Soo Kim, Mal-Soon Shin, and Young-Je Sim. “Treadmill Exercise Improves Short-Term Memory by Suppressing Ischemia-Induced Apoptosis of Neuronal Cells in Gerbils.” Neuroscience Letters. Vol. 372 (3). Dec 2004. 256-261.
Exercise training improves size of
hippocampus
A and B Scatterplots show the percent change in left and right hippocampus volume
with increase in aerobic fitness level. C and D Scatterplots show percent of change in
left and right hippocampus volume with an increase in BDNF levels. E and F
Scatterplots show percent change in left and right hippocampus increase in memory
performance.	
  	
  
Proceedings	
  of	
  the	
  Na1onal	
  Academy	
  of	
  Sciences	
  of	
  the	
  United	
  Sates	
  of	
  America,	
  
2011.	
  	
  
clker.com,	
  2007	
   clker.com,	
  2007	
  

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PhysioPosterFinal

  • 1. Exercise Intensity Impacts Short-Term Memory Allison Bader, Victoria Casani, Elizabeth Gillett, Christina Machado, and Dr. Usha Sankar Human Physiology BISC 3132, Fordham University, Bronx, NY   Background: As we age,  the size of our hippocampus, which controls memory and learning, shrinks. Studies have found that exercise negated the natural shrinking of the hippocampus, therefore protecting the individual from short-term memory loss (Alves, 2011). This has been demonstrated in studies of gerbils, where exercise was shown to suppress ischemia- induced apoptotic neuronal cell death in the denate gyrus of the hippocampus (Kim et al. 2004). Although exercise of any kind is found to have a positive affect on short-term memory, research points to a link between the intensity of aerobic exercise and its effects on short-term memory (Ellis et al. 1986). In addition, initial fitness level and age are significant factors that affect memory improvement (Blumenthal et al. 1988). Exercise has been shown to initiate growth factor cascades which affect structural and functional changes in the hippocampus, particularly increasing synaptic plasticity (Berchtold et al. 2007). If exercise intensity or duration increases, the debilitating effects of muscular fatigue may cancel the facilitative effects of exercise. An optimal level of aerobic exercise will increase blood circulation, nutrient delivery, and oxygen delivery to the brain, creating greater neural plasticity and enlargement of the hippocampus, a better cognitive performance, and an improved short-term memory. Aims: This study aims to investigate the impact of exercise on short- term memory by using memory tests from the Memory Assessment Scales. Data Results: Scores will be tabulated for each of the tests, and statistical significance calculations will be made. Numerous comparisons can then be made, such as between (1)  the pre-exercise state and the post-exercise state between age groups (2)  the pre-exercise state and the post-exercise state within an age group (3)  the pre-exercise state and the post-exercise state between the control and the experimental groups, (4)  between the post-high intensity and post-low intensity exercise within an age group, (5)  between the post-high intensity and post-low intensity exercise between age groups, and (6)  between the post-high intensity and post-low intensity exercise between the control and experimental groups. Experiment: This experiment will utilize memory tests from the Memory Assessment Scales developed between 1981-1990. Each group will be asked to complete the tests under 3 conditions: (1) while seated and relaxed prior to exercise, (2) after exercising at 75-80% intensity for 20 minutes, and (3) after exercising at 40-45% intensity for 20 minutes. The following short-term memory tests will be utilized: 1. List Learning. 2. Visual Span. 3. Names-Faces. Hypothesis: Individuals who exercise have better short- term memory capabilities than those who do not.   Methods: Each person in this study will be assessed for pre- existing conditions that may interfere with their ability to perform strenuous exercise. 3 groups of people will be used: 1. 50 people (25 female and 25 male) between ages 18-25 who do not exercise regularly. 2. 50 people (25 female and 25 male) between ages 45-55 who do not exercise regularly. 3. 50 people (25 female and 25 male) who exercise regularly (3-5 times per week). This group is the control. Literature Cited: Alves, Heloisa, Chandramallika Basak, Laura Chaddock, Kirk I. Erickson, Susie Heo, Jennifer S. Kim, Arthur F. Kramer, Stephen A. Martin, Edward McAuley, Brandt D. Pence, Ruchika Shaurya Prakash, Amanda Szabo, Victoria J. Vieira, Michelle W. Voss, Jeffrey A. Woods. “Exercise Training Increases Size of Hippocampus and Improves Memory.” Proceedings of the National Academy of Sciences. Vol. 108. February 2011. 3017-3022. Berchtold, Nicole C., Lori-Ann Christie, and Carl W. Cotman. “Exercise Builds Brain Health: Key Role of Growth Factor Cascades and Inflammation.” Trends in Neuroscience. Vol. 30 (9). Sept 2007. 464-472. Blumenthal, James A. and David J. Madden. “Effects of Aerobic Exercise Training, Age, and Physical Fitness on Memory-Search Performance.” Psychology and Aging. Vol. 3 (3). Sept 1988. 280-285. Ellis, Norman R. and Phillip D. Tomporowski. “Effects of Exercise on Cognitive Processes: A Review.” Psychological Bulletin. Vol. 99 (3). May 1986. 338-346. Kim, Chang-Ju, Jee-Youn Kim, Sung-Soo Kim, Mal-Soon Shin, and Young-Je Sim. “Treadmill Exercise Improves Short-Term Memory by Suppressing Ischemia-Induced Apoptosis of Neuronal Cells in Gerbils.” Neuroscience Letters. Vol. 372 (3). Dec 2004. 256-261. Exercise training improves size of hippocampus A and B Scatterplots show the percent change in left and right hippocampus volume with increase in aerobic fitness level. C and D Scatterplots show percent of change in left and right hippocampus volume with an increase in BDNF levels. E and F Scatterplots show percent change in left and right hippocampus increase in memory performance.     Proceedings  of  the  Na1onal  Academy  of  Sciences  of  the  United  Sates  of  America,   2011.     clker.com,  2007   clker.com,  2007