The document summarizes recommendations from a research study on interventions to address syphilis among gay men. It recommends: 1) Increasing testing frequency for syphilis among sexually active gay men, especially those with many partners, and ensuring testing is easily accessible. 2) Creating easier ways to discreetly notify partners and increasing education to reduce stigma around syphilis. 3) Proceeding with a proposed trial of syphilis chemoprophylaxis.

1. Summary of the NGMSAP Phase A Recommendations

2. Research underpinning recommendations: What interventions will be effective and acceptable? Intervention Modelling Social research Increase condom use Only effective if sustained long-term (years) Not acceptable over the long-term Reduce partner acquisition rates Only effective if sustained long-term (years) Not acceptable over the long-term Chemoprophylaxis Short/medium term intervention could have a moderate impact , large impact with long-term use Enthusiastic and widely acceptable Increased testing Very effective if targeted appropriately and with adequately high frequency Mass synchronised testing not acceptable, rapid testing is acceptable. Overall, increased testing is acceptable if more easily accessible/convenient . Mass treatment Only effective if a large % of population covered: unlikely to be effective Expect many men to be unwilling or unable to commit to activity Contact tracing/ partner notification Effective and efficient Diverse views but generally in support . Easier ways for notifying partners are required

5. Goal