Pigmentation is caused by overproduction of melanin by melanocytes, which is taken up by keratinocytes in the epidermis or deposited in the dermis. Chemical peels use acid solutions to remove the damaged outer layers of skin, signaling new cell growth and skin turnover. They are a popular treatment for skin disorders and signs of aging and work best when combined with other techniques as part of a tailored treatment plan. Potential side effects include temporary darkening or lightening of skin.