Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Nose & Paranasal sinuses.All Good Things
Dentist in pune. (BDS. MDS) - Dr. Amit T. Suryawanshi. Seminar- Nose & Paranasal sinuses.
Email ID- amitsuryawanshi999@gmail.com
Contact -Ph no.-9405622455
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USMLE RESP 02 nose and paranasal sinuses anatomy medical .pdfAHMED ASHOUR
The nose and paranasal sinuses are interconnected structures in the upper respiratory system that play essential roles in the respiratory and olfactory processes.
Disorders of the nose and paranasal sinuses can include sinusitis (inflammation of the sinuses), nasal polyps, deviated septum, and various infections.
Proper care and treatment are essential to maintain respiratory function and overall health.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Anatomy of nose dental courses /certified fixed orthodontic courses by Indian...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy has a unique training program & curriculum that provides students with exceptional clinical skills and enabling them to return to their office with high level confidence and start treating patients
State of the art comprehensive training-Faculty of world wide repute &Very affordable.
Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Nose & Paranasal sinuses.All Good Things
Dentist in pune. (BDS. MDS) - Dr. Amit T. Suryawanshi. Seminar- Nose & Paranasal sinuses.
Email ID- amitsuryawanshi999@gmail.com
Contact -Ph no.-9405622455
Subscribe our channel on youtube - Copy and paste this URL. https://www.youtube.com/channel/UC_gylEXTrjmEbbOTSXjuZ4Q/videos?view_as=public
Follow us on slideshare
USMLE RESP 02 nose and paranasal sinuses anatomy medical .pdfAHMED ASHOUR
The nose and paranasal sinuses are interconnected structures in the upper respiratory system that play essential roles in the respiratory and olfactory processes.
Disorders of the nose and paranasal sinuses can include sinusitis (inflammation of the sinuses), nasal polyps, deviated septum, and various infections.
Proper care and treatment are essential to maintain respiratory function and overall health.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Anatomy of nose dental courses /certified fixed orthodontic courses by Indian...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy has a unique training program & curriculum that provides students with exceptional clinical skills and enabling them to return to their office with high level confidence and start treating patients
State of the art comprehensive training-Faculty of world wide repute &Very affordable.
The framework of the nose consists of bone and cartilage. Two small nasal bones and extensions of the maxillae form the bridge of the nose, which is the bony portion. The remainder of the framework is cartilage and is the flexible portion. Connective tissue and skin cover the framework.
Air enters the nasal cavity from the outside through two openings: the nostrils or external nares. The openings from the nasal cavity into the pharynx are the internal nares. Nose hairs at the entrance to the nose trap large inhaled particles.
Paranasal sinuses are air-filled cavities in the frontal, maxilae, ethmoid, and sphenoid bones. These sinuses, which have the same names as the bones in which they are located, surround the nasal cavity and open into it. They function to reduce the weight of the skull, to produce mucus, and to influence voice quality by acting as resonating chambers.
The Nose and nasal cavity, anatomy, and clinical diseases of nasal cavity and...HamzehKYacoub
Nasal cavity is the most superior part of the respiratory system.
Blood supply of nose and Cavernous Sinus.
Epistaxis causes and locations.
Allergic Rhinitis and Non-allergic rhinitis with eosinophilia (NARES).
Ostiomeatal complex (OMC)
Sinusitis.
Nasal polyps.
Headaches types.
Neuralgia.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The framework of the nose consists of bone and cartilage. Two small nasal bones and extensions of the maxillae form the bridge of the nose, which is the bony portion. The remainder of the framework is cartilage and is the flexible portion. Connective tissue and skin cover the framework.
Air enters the nasal cavity from the outside through two openings: the nostrils or external nares. The openings from the nasal cavity into the pharynx are the internal nares. Nose hairs at the entrance to the nose trap large inhaled particles.
Paranasal sinuses are air-filled cavities in the frontal, maxilae, ethmoid, and sphenoid bones. These sinuses, which have the same names as the bones in which they are located, surround the nasal cavity and open into it. They function to reduce the weight of the skull, to produce mucus, and to influence voice quality by acting as resonating chambers.
The Nose and nasal cavity, anatomy, and clinical diseases of nasal cavity and...HamzehKYacoub
Nasal cavity is the most superior part of the respiratory system.
Blood supply of nose and Cavernous Sinus.
Epistaxis causes and locations.
Allergic Rhinitis and Non-allergic rhinitis with eosinophilia (NARES).
Ostiomeatal complex (OMC)
Sinusitis.
Nasal polyps.
Headaches types.
Neuralgia.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
3. Introduction
Air-containing cavities in the bones
around nasal cavity.
Paranasal air sinuses develop as
mucosal diverticulae of nasal cavity,
invading the adjacent bones.
Paranasal air sinuses perform the
following functions:
• Make the skull lighter.
• Add resonance to the voice.
• Act as air conditioning chambers by
making the inspired air moist and warm.
• Aid in growth of facial skeleton.
Paranasal air sinuses are lined by respiratory epithelium and
respiratory mucosa is highly vascular and contains a large
number of cavernous spaces and sinusoids to warm the air.
Respiratory mucosa also contains a large number of serous
glands and secretion of these glands makes the air moist.
4. Classification
Paranasal air sinuses are named
after the bones containing them,
viz,
• Frontal air sinuses.
• Ethmoidal air sinuses.
• Maxillary air sinuses.
• Sphenoidal air sinuses.
All paranasal air sinuses are
present in rudimentary form at birth
except frontal air sinuses.
5. Relationship to the Orbit
• Frontal air sinus- above.
• Ethmoidal air sinuses- medial.
• Maxillary air sinus- below.
• Sphenoidal air sinus- behind.
7. Introduction
Frontal air sinuses are not present at birth.
Start developing 2 or 3 years after birth.
Number- 2.
Shape- Triangular.
Lie between inner and outer tables of frontal bone.
Right frontal air sinus is separated from the left by a septum.
8. Drainage & Nerve Supply
• Drainage- Drains into anterior part of hiatus semilunaris of middle meatus
through frontonasal duct.
• Nerve Supply- Supraorbital nerve.
Hiatus
Semilunaris
10. Relations of Frontal Air Sinus
Anterior-
• Superciliary arch of forehead.
Posterior-
• Meninges and frontal lobe of
brain.
Inferior-
• Roof of nose.
• Roof of orbit (medial part).
• Ethmoidal air cells.
Frontal air sinus
Frontal lobe
11. Applied Aspects
Frontal Headache (Office Headache)
• Headache from frontal sinusitis shows characteristic periodicity.
• It starts on waking, gradually increases and reaches its peak by about
midday and then starts subsiding.
12. Applied Aspects contd…
Frontal Lobe Abscess-
• Infection of frontal air sinus
may spread posteriorly into
frontal lobe of brain causing
frontal lobe abscess.
Frontal air sinus
13. Applied Aspects contd…
Orbital Cellulitis-
• Infection of frontal air sinus may spread inferiorly into orbit causing orbital
cellulitis.
15. Introduction
• Largest paranasal air sinus.
• Present in body of maxilla.
• First to develop.
• Appears around 4th month of intrauterine life.
16. Maxillary Sinus contd…
SHAPE- Pyramidal.
Base-
• Directed medially.
• Formed by a part of lateral wall of nose.
• Opening or ostium of the sinus is present in the
upper part of base, close to the roof.
Apex-
• Directed laterally.
• Extends into zygomatic process of maxilla.
Roof-
• Formed by the floor of orbital cavity.
• Infraorbital nerve and artery traverse the roof in a
bony canal.
Floor-
• Formed by the alveolar process of maxilla.
• Lies ~1.25 cm below the floor of nasal cavity.
Zygomatic bone
Ostium of Maxillary air sinus
17.
18. Floor of Maxillary Sinus contd…
• The level of floor corresponds to
the ala of nose.
• Normally the roots of first and
second molar teeth project into the
floor.
• Sometimes roots of third molar, first
and second premolars may project
into the floor.
• Rarely, root of canine may project
into the floor.
• Sometimes roots of teeth are
separated from the sinus only by a
thin layer of mucosa.
19. Base of Maxillary Sinus
• It is formed by medial surface of body of maxilla and
some other bones.
• In maxilla, medial surface of its body presents a large
maxillary hiatus.
• In the skull, base of maxillary sinus presents a small
opening ( ostium).
Maxillary Hiatus
20. Reduction of large maxillary hiatus to small
ostium
• It occurs by the following bones:
• Uncinate process of ethmoid.
• Descending process of lacrimal.
• Ethmoidal process of inferior
nasal concha.
• Perpendicular plate of palatine.
21. Maxillary Sinus contd…
Anterior wall-
• Has a curved bony canal for
anterior superior alveolar
nerve – Canalis Sinuosus.
Posterior wall-
• Separates the sinus from
infratemporal and
pterygopalatine fossae.
• It is pierced by the posterior
superior alveolar nerves and
vessels.
22. Drainage
• In posterior part of hiatus semilunaris of middle meatus.
Hiatus Semilunaris
Opening of
Maxillary Sinus
23. Arterial Supply
• Anterior superior alveolar
artery.
• Middle superior alveolar
artery.
• Posterior superior alveolar
artery.
25. Nerve Supply
• Anterior superior alveolar
nerve.
• Middle superior alveolar
nerve.
• Posterior superior alveolar
nerve.
26. Applied Aspects
Maxillary Sinusitis-
• Maxillary sinus is the most commonly infected paranasal air sinus.
• The opening of maxillary sinus is in a disadvantageous position for natural drainage.
Sources of infection:
• Infected nose.
• Carious upper premolar and molar teeth.
• Infected frontal and anterior ethmoidal air sinuses.
27. Surgical Drainage of Maxillary Sinus
Antral puncture (Antrostomy)-
• Trocar and canula are passed below the inferior nasal concha in an outward and backward
direction.
Caldwell-Luc operation-
• Maxillary sinus is opened through gingiva-labial sulcus.
28. Applied Aspects contd…
Carcinoma of Maxillary Sinus-
• Arises from mucosa of the sinus.
Clinical Features-
Due to upward invasion:
• Proptosis (protrusion of eyeball).
• Diplopia (double vision).
• Pain and anaesthesia over the face below the orbit.
Due to downward invasion:
• Swelling or even ulceration of palatal roof of oral cavity.
Due to medial invasion:
• Nasal obstruction.
• Epistaxis.
• Epiphora (overflow of tears).
Due to lateral invasion:
• Swelling on the face and palpable mass in gingiva-labial sulcus.
Due to posterior invasion:
• Referred pain to upper teeth.
30. Introduction
Present within labyrinth of ethmoid bone.
Between upper part of lateral nasal wall and orbit.
3 groups:
• Anterior (up to 11 air cells).
• Middle (1-3 air cells).
• Posterior (1-7 air cells).
31. Drainage
• Anterior group drains into middle part of hiatus seminularis of middle meatus.
• Middle group drains on the surface of bulla ethmoidalis of middle meatus.
• Posterior group drains into posterior part of superior meatus.
32. Applied Aspects
Ethmoidal Sinusitis-
• Often asoociated with
infection of other sinuses.
Clinical Features-
Localized pain over bridge of
nose.
Due to invasion into the orbit-
• Orbital cellulitis.
37. Applied Aspects
Sphenoidal Sinusitis-
• One of The Most Dangerous Sinus
Infection.
• It is rare in isolation.
• It is usually a part of pansinusitis.
• It may be associated with infection
of posterior ethmoidal sinuses.