This document discusses PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections). PANDAS is an autoimmune disorder where antibodies meant to fight strep infections instead attack the basal ganglia of the brain, causing symptoms like obsessive-compulsive disorder, tics, anxiety, and issues with focus and motor skills. The cause is believed to be molecular mimicry. Diagnosis and treatment options are discussed.

1. PANDAS
Dr. Suresh. S.S. Raja
Assistant Professor
Department of Microbiology
Bharathidasan University College
Perambalur-621107
PREPARED ON 27.11.2016

3. Symptoms are…..

4. Neuropsychiatric conditions
Obsessions (e.g.,
preoccupation with
a fixed idea or an unwanted
feeling, often accompanied by
anxiety)
Compulsions (e.g., an
irresistible impulse to act,
regardless of the
rationality of the motivation)

5. Neuropsychiatric conditions- fear

6. Neuropsychiatric conditions - anxiety

9. Neuropsychiatric conditions - eneuresis

11. Dysgraphia

12. Dyscalcula

14. Conditions - Hyperactvity, impulsivity, fidgetiness or inability to
focus

17. Cause – molecular mimicry

18. Cause – molecular mimicry

19. Cause – molecular mimicry
PANDAS - an autoimmune
disorder in which antibodies
meant to fight strep
infections attack the basal
ganglia of the brain, resulting
in tic,TS,OCD

20. Diagnosis

21. Treatment

23. Conclusion
• “There are a terrible lot of lies going
around the world, and the worst of it is
half of them are true.”
Sir Winston Churchill British politician (1874 - 1965)
Recognise and educate

24. THANK YOU