1. Original.
Below are a few selected sentences from the Introduction, Results, and Discussion sections of
several published articles. I did not attempt to make it into a coherent story. I replaced most
scientific terms with unrelated expressions.
Introduction
Understanding network topology through embracing the global dynamical regulation of genes in an
active state space rather than traditional one-gene–one trait approach facilitates the understanding
of gene regulation in retinoblastoma.
The availability of genomic data of several forms of retinoblastoma opened new avenues to
understand disease novel pathophysiology that can be harnessed to progression of the disease.
Many evidence suggests that lipids are essential in the progression of retinoblastoma, and its
regulation mechanisms are largely unknown…
Overexpression of protein X has been related to repression of regulatory genes, but a functional
study of the role of protein X in the development and progression of retinoblastoma has not yet
been investigated.
It has been proved that protein Y gene located on chromosome 1, tightly close close to rs1111111,
is associated with increased risk for retinoblastoma.
Results
We investigated the expression of protein X in retinoblastoma cancer cells in vitro in five
retinoblastoma cell lines. In addition, we detected protein X expression in retinoblastoma tissue
specimens by RT-PCR.
Taken together, protein X acts as an oncogene in retinoblastoma. It may play an important role in
cell proliferation, cell metastasis and inhibition of apoptosis.
Discussion
Recently, there has been a noted increase in interest in protein Y as a mediator in tumor
development, due to an association between extensive overexpression of this protein in tumor
vasculature and tumor progression that leads to poor clinical outcome.
There are still some limitations in this study.

2. The built model clarifies the relative importance of various reactions in a metabolic pathway.
Altogether with the findings we show the system that poised to sense the metabolic response and
metabolic imbalances, illustrating extensive communication in the metabolic network.
The current model posts the stress on the role of epigenetic regulation in retinoblastoma.