OpenSpecimen is used across multiple disease groups at the Siteman Cancer Center as the primary biospecimen management database. It has over 1000 studies, 100 sites, 80 active users, and over 2 million specimens stored. OpenSpecimen integrates with other systems like REDCap to automate data entry and improve reporting. It also integrates with BioMS to sync clinical trial data from over 3000 collection sites for the Alliance for Clinical Trials in Oncology network. OpenSpecimen provides a configurable, robust platform for biorepository management with ongoing support and improvements.

1. OPENSPECIMEN
USAGE
Dave Mulvihill, Director of Informatics
Lee Myrick, Clinical Informaticist
Siteman Cancer Center

2. AGENDA
• Background and Usage at WU
• Integrations: REDCap, BioMS and others
• Summary

3. Enterprise Wide Usage
Used across multiple disease groups as the
primary biospecimen management database.

4. Why we use
OpenSpecimen?
Configurability
Reporting
Support for multi-groups
Speed
Open source community
Support from developers

5. History
2004 - 2010
Started caTissue development
2006 - 2012
caTissue Adopted in WU
2013 - 2017
Local customized version
2018 - today
Upgraded to OpenSpecimen

6. Usage
Statistics
1000+ Studies
100+ Sites
80+ Active Users
200K+ Participants
2 million+ Specimens
1200+ Storage Containers

7. Some of our main users

8. Siteman Cancer Center
Tissue Procurement Core
Centralized resource to collect, store and utilize
human biospecimens for cancer research.

9. Alzheimer's Disease
Research Center (ADRC)
Forefront of a worldwide effort to uncover key causal
factors in the development of Alzheimer's

10. Kidney Translational
Research Center
Provides data and a biospecimens from more than
3500 patients (adults and children) with kidney
diseases

11. Integrations
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12. Integration

13. Why integrate with REDCap?
IMPROVE STAFF
PRODUCTIVITY
Eliminate Manual Data Entry
AUTOMATION
Reduce Data Entry Errors
BETTER REPORTING
Find “Specimens Of Interest” Using Fields Across
Openspecimen And REDCap

14. REDCap OpenSpecimen
Auto-register new subjects
every 5 mins
Sync clinical data
nightly

15. Managing Specimens for
Large Multi-site Project

16. Alliance for Clinical Trials
in Oncology
Develops and conducts clinical trials with new cancer
therapies, and develop optimal treatment and prevention
strategies for cancer

17. Statistics
Part of National Clinical Trial
Network (NCTN)
Funded by National Cancer Institute
(NCI)
3000+ collection sites across USA,
Canada and others
100K+ specimens collected across
66 clinical trials

18. BioMS Integration
Alliance users across 3000+ sites use the BioMS
application to register subjects, create primary
specimens and shipments.

19. Auto-register new trials, subjects,
and primary specimens
Sync shipments sent from
collection sites to WU
Specimen data is
synchronized back to BioMS

20. Other Integrations
Qubit TapeStation Financial System

21. Future
Project tracker: Track biospecimens projects and
services within OpenSpecimen.
Specimen Kiosk: Manage specimen drop-off and
pick-up using touch-screen based on “kiosk”

22. Summary
OpenSpecimen is a robust, enterprise worthy
informatics platform for biorepository management.
Modern features, open-source and pluggable
architecture and community support.

23. Questions?