This presentation belongs to a talk I have given at the conference "Wittgensteinian Approaches to Moral Philosophy" at the University of Leuven, Belgium, 17.-19.9.2015
This is the presentation which accompanied my talk "Human Dignity as a Mythological Concept" I gave at the conference "The future of human dignity" in Utrecht, October 10-13, 2016.
This is the presentation of my talk "Motion Picture, World-Picture, and Surveyable Representation" I gave at the Film-Philosophy-Conference at Lancaster University, July 4-6, 2017.
This is the presentation which accompanied my talk "Human Dignity as a Mythological Concept" I gave at the conference "The future of human dignity" in Utrecht, October 10-13, 2016.
This is the presentation of my talk "Motion Picture, World-Picture, and Surveyable Representation" I gave at the Film-Philosophy-Conference at Lancaster University, July 4-6, 2017.
Introduction to the Philosophy of Human Person - What is the TruthJuan Miguel Palero
This is a powerpoint presentation that discusses about one of the core subjects in the k-12 curriculum of the Senior High School: Introduction to the Philosophy of the Human Person. On this presentation, it discusses about the definition and philosophical definition of truths and axioms.
Ron takes the debate over to mind v matter into language - which is where the mystery of mind is best revealed. He gives us a crash course in philosophy in ten minutes - and uses the colour 'red' to reveal the immense complexity in simply naming the world. The highlight though belongs to his one year old grandson , Levi - and he uses Levi's early experiments with words to celebrate the wonders of the mind at work through language and how we acquire it.
I. The Passing of Materialism . . 13
II. The Claim of the Bible ... 17
III. Transformation of Life ... 22
IV. The World-system : Its Origin . . 25
V. The Seeds of Doubt 31
VI. The Gospel of Self 35
Die Präsentation zur Reihe Film(&)Philosophie im Schlachthofkino Soest. Thema: Der Mensch und die Technik am Beispiel von Stanley Kubricks 2001 - Odyssee im Weltraum und Martin Heideggers Text Die Technik.
Introduction to the Philosophy of Human Person - What is the TruthJuan Miguel Palero
This is a powerpoint presentation that discusses about one of the core subjects in the k-12 curriculum of the Senior High School: Introduction to the Philosophy of the Human Person. On this presentation, it discusses about the definition and philosophical definition of truths and axioms.
Ron takes the debate over to mind v matter into language - which is where the mystery of mind is best revealed. He gives us a crash course in philosophy in ten minutes - and uses the colour 'red' to reveal the immense complexity in simply naming the world. The highlight though belongs to his one year old grandson , Levi - and he uses Levi's early experiments with words to celebrate the wonders of the mind at work through language and how we acquire it.
I. The Passing of Materialism . . 13
II. The Claim of the Bible ... 17
III. Transformation of Life ... 22
IV. The World-system : Its Origin . . 25
V. The Seeds of Doubt 31
VI. The Gospel of Self 35
Die Präsentation zur Reihe Film(&)Philosophie im Schlachthofkino Soest. Thema: Der Mensch und die Technik am Beispiel von Stanley Kubricks 2001 - Odyssee im Weltraum und Martin Heideggers Text Die Technik.
Präsentation zur Einführung in Andre Dominiks "Die Ermordung des Jesse James durch den Feigling Robert Ford". Thema der Einführung: Narration (Ricoeur, Foucault)
Die Präsentation zum Film "The Imitation Game" über mathematische Grundlagenfragen: Berechenbarkeit, Entscheidbarkeit, Hilbert-Programm und die Turing-Maschine.
Das Thema Wertverlust in der Moderne war Gegenstand der Diskussion des Films The Bling Ring von Sofia Coppola im Rahmen der Reihe Film(&)Philosophie im Schlachthofkino in Soest.
Dr. John Oakes taught a class on Modernism and Scientific Materialism at the 2015 International Christan Evidence Conference at York College in York, Nebraska, June 19-21. He gave a brief overview of the history of modern science and then give a world view critique of the philosophy, comparing it to Christianity. Here are notes and power points from the presentation.
An Introduction to Philosophy
Lecture 01: Introduction
James Mooney
Open Studies
The University of Edinburgh
j.mooney@ed.ac.uk
www.filmandphilosophy.com
@film_philosophy
Evolutionary epistemology versus faith and justified true belief: Does scien...William Hall
This presentation explores the basis for scientific rationality by testing our claims about the world against nature as described by Karl Popper's evolutionary epistemology versus accepting claims based on justified true belief. The presentation is particularly concerned to show the philosophical problems with religious fundamentalism.
This presentation presents the second of three core arguments for the existence of God and presents evidence for God being the intelligent cause of the universe.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
On Ethics and Mythology
1. On Ethics And Mythology
A Wittgensteinian Point ofView
Thomas Wachtendorf
wachtendorf@akademiephilosophie.de
Research center Erkenntnis, University of Oldenburg, Germany
Wittgensteinian Approaches to Moral Philosophy (Second Edition)
University of Leuven, Belgium
2. Thomas Wachtendorf
1. The initial question
2. Classification of sentences
3. World-Picture
4. Ethics as Mythology
5. Attitude
6. Seeing-As
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
3. Thomas Wachtendorf
The crucial question:
Are ethical sentences empirical or merely
conventional?
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
4. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
„That I am a man and not a woman can be
verified […].“ (OC §79)
5. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
B: Grammatical sentences
„Example: ‚Every rod has a length.‘ That means
something like: we call something (or this) ‚the
length of a rod‘—but nothing ‚the length of a
sphere.‘ […] But the picture attaching to the
grammatical proposition could only shew, say,
what is called ‚the length of a rod‘“. (PI, §251)
6. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
B: Grammatical sentences
C: Regulative sentences
„The propositions presenting what Moore ‘knows’
are all of such a kind that it is difficult to imagine why
anyone should believe the contrary. E.g. the proposition that
Moore has spent his whole life in close proximity to the earth.
– Once more I can speak of myself here instead of speaking of
Moore.What could induce me to believe the opposite? Either
a memory, or having been told. – Everything that I have seen or
heard gives me the conviction that no man has ever been far
from the earth. Nothing in my picture of the world speaks
in favour of the opposite.“(OC §93)
7. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
B: Grammatical sentences
C: Regulative sentences
D: Empirical, but not yet verified sentences
„As children we learn facts; e.g., that every human
being has a brain, and we take them on trust. I believe
that there is an island,Australia, of such–and–such a
shape, and so on and so on; I believe that I had great–
grandparents, that the people who gave themselves out
as my parents really were my parents, etc.This belief
may never have been expressed; even the thought that
it was so, never thought.“ (OC §159)
8. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
B: Grammatical sentences
C: Regulative sentences
D: Empirical, but not yet verified sentences
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„The propositions describing this world–picture
might be part of a kind of mythology.And their role is like
that of rules of a game; and the game can be learned purely
practically, without learning any explicit rules.“ (OC §95)
„An entire mythology is stored within our language.“ (RGB
133)
➡Mythological sentences either can’t be doubted and validated (A) or to
doubt them would be completely strange, because they are either not
used as empirical sentences or are self-evident (B, C) or they are
awaiting validation (D).
9. Thomas Wachtendorf
This mythology constitutes a world-picture
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
„That is to say, the questions that we raise and our
doubts depend on the fact that some propositions are exempt
from doubt, are as it were like hinges on which those
turn.“ (OC §341)
„At the foundation of well–founded belief lies belief that is
not founded.“ (OC §253)
„That is to say, it belongs to the logic of our scientific
investigations that certain things are in deed not doubted.“ (OC
§342)
„What I hold fast to is not one proposition but a nest of
propositions.“ (OC §225)
„But I did not get my picture of the world by satisfying myself
of its correctness; nor do I have it because I am satisfied of its
correctness. No: it is the inherited background against which I
distinguish between true and false.“ (OC §94)
10. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
B: Grammatical sentences
C: Regulative sentences
Where is the place for ethical sentences?
Ethical sentences:
•can be doubted (∉ B)
•are no empirical sentences (∉ A ∧ ∉ D)
D: Empirical, but not yet verified sentences
•are not self-evident (∉ C)
11. Thomas Wachtendorf
A: Empirical sentences
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
B: Grammatical sentences
C: Regulative sentences
Where is the place for ethical sentences?
In a subset of C!
Ethical sentences:
•can be doubted
•are no empirical sentences
D: Empirical, but not yet verified sentences
•are not self-evident
C1: Ethical sentences
12. Thomas Wachtendorf
Ethics as Attitude
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
In this context I define the notion of attitude as
follows:
Attidude ≔The class of all sentences expressing
the dispositions how one reacts to the world.
An attitude – so to speak – frames one’s actions.
13. Thomas Wachtendorf
Ethics as Attitude
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
„It might be imagined that some propositions, of the form of
empirical propositions, were hardened and functioned as channels for
such empirical propositions as were not hardened but fluid; and that
this relation altered with time, in that fluid propositions hardened, and
hard ones became fluid.“ (OC §96)
Accepting certain (ethical) sentences changes
one’s attitude and also one's world-picture:
„The mythology may change back into a state of flux, the river–
bed of thoughts may shift. But I distinguish between the movement of
the waters on the river–bed and the shift of the bed itself; though
there is not a sharp division of the one from the other.“ (OC §97)
„And the bank of that river consists partly of hard rock, subject
to no alteration or only to an imperceptible one, partly of sand, which
now in one place now in another gets washed away, or
deposited.“ (OC §99)
14. Thomas Wachtendorf
Seeing-As
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
The World-picture influences the way we see the
world:
„You only ‚see the duck and
rabbit aspects‘ if you are already
conversant with the shapes of those
two animals.“ (PI II 207)
„The world of the happy man is a different one
from that of the unhappy man.“ (TLP 6.43)
This is why:
15. Thomas Wachtendorf
Conclusion
1. The initial question
2. Classification
3. World-picture
4. Ethics as Mythology
5. Attitude
6. Seeing-as
On Ethics and Mythology
A world-picture rests on mythology and because
of ethical sentences being part of this mythology,
each world-picture also has a ethical foundation.
To accept or decline certain sentences influences
this mythology and therefore changes ethics.
Ethics, in conclusion, is not just discussing ethical
questions, but rather changing one’s way of seeing
the world – as we go along.
To be ethical in this sense means to adopt a
certain attitude by taking ethical sentences into
consideration and accept or decline them.
16. On Ethics And Mythology
A Wittgensteinian Point ofView
Thomas Wachtendorf
wachtendorf@akademiephilosophie.de
Research center Erkenntnis, University of Oldenburg, Germany
Wittgensteinian Approaches to Moral Philosophy (Second Edition)
University of Leuven, Belgium