Chapter 15 - The Digestive System
Irregular tube; open at both ends, called
“Alimentary canal” or “Gastrointestinal (GI) Tract”

29 feet long (adults) - 9 meters

Food & other substances that enter tube are not really
inside body

Passageway of food: broken down (digested) and
absorbed thru walls < entering body - cells
Both - Mechanical & Chemical Digestion
Break Down of Food
Teeth- first physical breakdown
Stomach-churning of food (physical)
Mouth- first chemical breakdown (salvia)
Digestive enzymes throughout GI tract
Digestion - Process where large food particles
reduced to absorbable molecules
Absorption - Process of small molecules passing thru
digestive system walls into body
Key Organs of the GI Tract
Know Main & Accessory organs, Table 16-2; page
476
Small Intestine : Duodenum, Jejunum, & Ileum
Large Intestines (elimination > feces):
Cecum, Colon: Ascending, Transverse, Descending,
Sigmoid
Wall of Digestive Tract -

Mouth to anus

Four layers of tissue; surrounding the hollow
space within the tube “lumen”

May vary in structure in different organs

Mucosa or mucous membrane - tough in
esophagus, delicate, for absorption or
secretion in rest of tract

Submucosa - connective tissue, blood
vessels & nerves

Muscularis - 2 layers, responsible for
wavelike, rhythmic contractions
(peristalsis), moves contents, assists in
mixing & mechanical breakdown

Serosa - outermost covering, composed
of visceral peritoneum

Mesentery - double folded peritoneal
tissue, anchors loops of digestive tract to
posterior wall of abdominal cavity
Mouth -

Oral cavity - hollow chamber (roof, a floor, & walls)

Entrance of food; digestion begins immediately

Mucous membranes > mucus, protects against
digestive juices & lubricates food passage

This mucous protects & lubricates

Hard palate - bony structure, front portion

Soft palate - posterior, chiefly muscles

Uvula - cone-shaped process hanging down from
soft palate. W/ help of soft pal., prevents food or
liquid from entering nasal cavity
Floor of the mouth -
Tongue - skeletal muscular structure, covered w/
mucous membrane

Anchored to bones in skull > hyoid bone
Frenulum- thin membrane; attaches tongue to floor
of mouth

Tongue-tied: too short
Papillae: small elevations on surface

Vallate type - largest, inverted V-shaped row of about
10-12 mushroomlike elevations - tastebuds
Teeth -
Four major types -

Incisors - (sharp/cutting)

Canines - cuspids (pierce/tear)

Premolars - bicuspids & Molars - tricuspids
(grinding/crush)
Mastication > chewing of food
Forms a bolus > ready for swallowing
By age 2 - full set 20 teeth (cut 1st - 2 yrs.)
By age 17 to 24 - 32 permanent teeth (cut 1st - 6
yrs.)
Typical Tooth -
Three main parts -

Crown - visible, covered w/ enamel (hardest tissue
in body)

Neck - narrow portion surrounds by gum tissue
(gingiva)

Root - fitted into socket in upper or lower jaw,
lined by fibrous, periodontal membrane

Inside Structure - Enamel on outside, Dentin, Pulp
cavity (blood vessels & nerves) moving inward
Salivary Glands -
3 Pairs - ducts drain saliva into oral cavity,
secretes about 1 liter/day

Parotid - in front of each ear (mumps -
tender)

Submandibular - ducts by fernullum

Sublingual - ducts into floor of mouth
Saliva contents - salivary amylase (begins
CHO digestion), mucus (moistens food)
Pharynx -

Behind nasal cavity & mouth

Tubelike structure made of muscles, lined w/
mucous membrane

Part of respiratory & digestive systems
Esophagus -

Passage for food to stomach

Tube-like structure, 10 inches long

Mucous lined

GERD - often caused by hiatal hernia
Stomach -

Upper part of abdominal cavity, under
diaphragm

Pouch for food, hollow, expands (can push up
on diaphragm > discomfort)

Lower esophageal sphincter (LES) or cardiac
sphincter - rings of muscle tissue at end of
esophagus - keeps food from reentering the
esophagus when the stomach contracts

Chyme - semi-solid mixture, produced
by contraction of stomach muscles that
mixes food w/ gastric juices
Stomach contractions -
Created by 3 layers of muscles, run
lengthwise, around, obliquely
Makes stomach one of strongest organs >
peristalsis
Breaks food into tiny particles

Mucous membranes line stomach -
contains gastric glands > secrete gastric
juice & hydrochloric acid

When empty, wrinkled folds - rugae
Three divisions of stomach -

Fundus, body, pylorus
Pyloric sphincter - holds food in stomach,
empties contents slowly into small
intestine

Ulcer - carterlike wound or sore in membrane of
stomach
• 1 in 10 persons suffer in USA
• Helicobacter pylori bacterium (H. pylori)
Small Intestines -

Portion of digestion tract that extends from the pylorus to
the ileocecal valve

12- 20 feet in length, coiled, convoluted, and occupies
most of the abdominal cavity

Intestinal glands - secrete digestive juices

Smooth muscle wall - contracts > peristalsis

Plicea - circular folds covered w/ villi,
increases surface area > absorption

In or on the villi -

Blood capillaries - absorb CHO & protein end
products (glucose & amino acids)

Lacteal - lymphatic vessel - absorb lipids

Microvilli - brushlike border, > surface more

Chemical digestion - most occurs in 1st
subdivision of duodenum

Minor & major duodenal papillae - ducts where
pancreatic enzymes & bile enter small intestine
Liver -

Large organ, fills R upper abdominal cavity

Exocrine gland - secretes bile into ducts

Hepatic - means liver

Bile - essential for breaking up or emulsification of
fats

CCK (cholecystokinin) - hormone secretion
triggered by lipids in chyme > makes gallbladder
contract & release bile

Drains from common bile duct into duodenum
Gallbladder - concentrates & stores bile
Pancreas -
C-shaped, exocrine gland that lies behind the
stomach & duodenum
Pancreatic juice - most important digestive juice -
contains enzymes for all 3 food groups
Sodium bicarbonate (alkaline substance) -
neutralizes hydrochloric acid
Enters small intestine thru same duct as bile
Islets of Langerhans - hormones produced
Pancreatitis - inflammation (blockage, CF)
Large Intestine -
Begins with the ending of the ileum at the ileocecal
valve - called the cecum
Approximately 5 feet in length, much larger in
diameter than small intestine
Contents - not called chyme
Function - reabsorb water & salts
Material acted on by bacteria > more nutrients from
cellulose & other fibers

Synthesis Vit. K needed for blood clotting,

Production of some B-complex vit.
Not as well suited for absorption as small intestine -
no villi
Normal passage of material thru large intestine - 3 to
5 days
Subdivisions - flow in GI Tract one-way
Cecum - pouchlike area
Ascending colon - right side of body

Bends at hepatic or right colic flexure
Transverse colon - extends across front

Bends at splenic or left colic flexure
Descending colon - left side abdomen
Sigmond colon - S-shaped segment,
terminates in rectum
Anal canal - terminal end of rectum, ends at
external opening - anus
Inner anal sphincter - involuntary, smooth
muscle, keeps anus closed except during
defecation
Outer anal sphincter - striated, voluntary
muscle
Appendix -

Vermiform appendix - “worm-shaped”, tubular structure,
blind tube

No important digestive fnc. - digest cellulose

Appendicitis - inflammation
Peritoneum -

Large, moist, slippery sheet of serous membrane

Peritoneal space - small space between parietal & visceral
layers - surfaces slide freely

Retroperitoneal - organs outside peritoneum

Extensions of peritoneum-mesentary, greater omentum -
both assist in anchoring abd. contents
Digestion -Chemical & mechanical breakdown
CHO - amylase in mouth, slight effect
amylase from pancreas - into small intestine

Absorption of simple sugars (glucose)
Proteins - stomach (HCL/pepsinogen> pepsin)

Finished in small intestine by pancreatic (trypsin)
& peptidases in intestinal juice

Amino acids - basic protein units
Fats - in small intestine

Bile emulsification of fats > pancreatic
lipase > fatty acids & glycerol
Key digestive juices & enzymes
* page 410 Table 15-2
Absorption - taking food, breaking it
down in form for utilization of body
Just as important as digestion

NUR101-ModulebbbbbbbbbbbbbbbbbbbbbbbbbbbO.ppt

  • 1.
    Chapter 15 -The Digestive System Irregular tube; open at both ends, called “Alimentary canal” or “Gastrointestinal (GI) Tract”  29 feet long (adults) - 9 meters  Food & other substances that enter tube are not really inside body  Passageway of food: broken down (digested) and absorbed thru walls < entering body - cells Both - Mechanical & Chemical Digestion
  • 2.
    Break Down ofFood Teeth- first physical breakdown Stomach-churning of food (physical) Mouth- first chemical breakdown (salvia) Digestive enzymes throughout GI tract Digestion - Process where large food particles reduced to absorbable molecules Absorption - Process of small molecules passing thru digestive system walls into body
  • 3.
    Key Organs ofthe GI Tract Know Main & Accessory organs, Table 16-2; page 476 Small Intestine : Duodenum, Jejunum, & Ileum Large Intestines (elimination > feces): Cecum, Colon: Ascending, Transverse, Descending, Sigmoid
  • 4.
    Wall of DigestiveTract -  Mouth to anus  Four layers of tissue; surrounding the hollow space within the tube “lumen”  May vary in structure in different organs  Mucosa or mucous membrane - tough in esophagus, delicate, for absorption or secretion in rest of tract  Submucosa - connective tissue, blood vessels & nerves
  • 5.
     Muscularis - 2layers, responsible for wavelike, rhythmic contractions (peristalsis), moves contents, assists in mixing & mechanical breakdown  Serosa - outermost covering, composed of visceral peritoneum  Mesentery - double folded peritoneal tissue, anchors loops of digestive tract to posterior wall of abdominal cavity
  • 6.
    Mouth -  Oral cavity- hollow chamber (roof, a floor, & walls)  Entrance of food; digestion begins immediately  Mucous membranes > mucus, protects against digestive juices & lubricates food passage  This mucous protects & lubricates  Hard palate - bony structure, front portion  Soft palate - posterior, chiefly muscles  Uvula - cone-shaped process hanging down from soft palate. W/ help of soft pal., prevents food or liquid from entering nasal cavity
  • 7.
    Floor of themouth - Tongue - skeletal muscular structure, covered w/ mucous membrane  Anchored to bones in skull > hyoid bone Frenulum- thin membrane; attaches tongue to floor of mouth  Tongue-tied: too short Papillae: small elevations on surface  Vallate type - largest, inverted V-shaped row of about 10-12 mushroomlike elevations - tastebuds
  • 8.
    Teeth - Four majortypes -  Incisors - (sharp/cutting)  Canines - cuspids (pierce/tear)  Premolars - bicuspids & Molars - tricuspids (grinding/crush) Mastication > chewing of food Forms a bolus > ready for swallowing By age 2 - full set 20 teeth (cut 1st - 2 yrs.) By age 17 to 24 - 32 permanent teeth (cut 1st - 6 yrs.)
  • 9.
    Typical Tooth - Threemain parts -  Crown - visible, covered w/ enamel (hardest tissue in body)  Neck - narrow portion surrounds by gum tissue (gingiva)  Root - fitted into socket in upper or lower jaw, lined by fibrous, periodontal membrane  Inside Structure - Enamel on outside, Dentin, Pulp cavity (blood vessels & nerves) moving inward
  • 10.
    Salivary Glands - 3Pairs - ducts drain saliva into oral cavity, secretes about 1 liter/day  Parotid - in front of each ear (mumps - tender)  Submandibular - ducts by fernullum  Sublingual - ducts into floor of mouth Saliva contents - salivary amylase (begins CHO digestion), mucus (moistens food)
  • 11.
    Pharynx -  Behind nasalcavity & mouth  Tubelike structure made of muscles, lined w/ mucous membrane  Part of respiratory & digestive systems Esophagus -  Passage for food to stomach  Tube-like structure, 10 inches long  Mucous lined  GERD - often caused by hiatal hernia
  • 12.
    Stomach -  Upper partof abdominal cavity, under diaphragm  Pouch for food, hollow, expands (can push up on diaphragm > discomfort)  Lower esophageal sphincter (LES) or cardiac sphincter - rings of muscle tissue at end of esophagus - keeps food from reentering the esophagus when the stomach contracts
  • 13.
     Chyme - semi-solidmixture, produced by contraction of stomach muscles that mixes food w/ gastric juices Stomach contractions - Created by 3 layers of muscles, run lengthwise, around, obliquely Makes stomach one of strongest organs > peristalsis Breaks food into tiny particles
  • 14.
     Mucous membranes linestomach - contains gastric glands > secrete gastric juice & hydrochloric acid  When empty, wrinkled folds - rugae Three divisions of stomach -  Fundus, body, pylorus Pyloric sphincter - holds food in stomach, empties contents slowly into small intestine
  • 15.
     Ulcer - carterlikewound or sore in membrane of stomach • 1 in 10 persons suffer in USA • Helicobacter pylori bacterium (H. pylori) Small Intestines -  Portion of digestion tract that extends from the pylorus to the ileocecal valve  12- 20 feet in length, coiled, convoluted, and occupies most of the abdominal cavity  Intestinal glands - secrete digestive juices  Smooth muscle wall - contracts > peristalsis
  • 16.
     Plicea - circularfolds covered w/ villi, increases surface area > absorption  In or on the villi -  Blood capillaries - absorb CHO & protein end products (glucose & amino acids)  Lacteal - lymphatic vessel - absorb lipids  Microvilli - brushlike border, > surface more  Chemical digestion - most occurs in 1st subdivision of duodenum  Minor & major duodenal papillae - ducts where pancreatic enzymes & bile enter small intestine
  • 17.
    Liver -  Large organ,fills R upper abdominal cavity  Exocrine gland - secretes bile into ducts  Hepatic - means liver  Bile - essential for breaking up or emulsification of fats  CCK (cholecystokinin) - hormone secretion triggered by lipids in chyme > makes gallbladder contract & release bile  Drains from common bile duct into duodenum Gallbladder - concentrates & stores bile
  • 18.
    Pancreas - C-shaped, exocrinegland that lies behind the stomach & duodenum Pancreatic juice - most important digestive juice - contains enzymes for all 3 food groups Sodium bicarbonate (alkaline substance) - neutralizes hydrochloric acid Enters small intestine thru same duct as bile Islets of Langerhans - hormones produced Pancreatitis - inflammation (blockage, CF)
  • 19.
    Large Intestine - Beginswith the ending of the ileum at the ileocecal valve - called the cecum Approximately 5 feet in length, much larger in diameter than small intestine Contents - not called chyme Function - reabsorb water & salts Material acted on by bacteria > more nutrients from cellulose & other fibers  Synthesis Vit. K needed for blood clotting,  Production of some B-complex vit.
  • 20.
    Not as wellsuited for absorption as small intestine - no villi Normal passage of material thru large intestine - 3 to 5 days Subdivisions - flow in GI Tract one-way Cecum - pouchlike area Ascending colon - right side of body  Bends at hepatic or right colic flexure Transverse colon - extends across front  Bends at splenic or left colic flexure Descending colon - left side abdomen
  • 21.
    Sigmond colon -S-shaped segment, terminates in rectum Anal canal - terminal end of rectum, ends at external opening - anus Inner anal sphincter - involuntary, smooth muscle, keeps anus closed except during defecation Outer anal sphincter - striated, voluntary muscle
  • 22.
    Appendix -  Vermiform appendix- “worm-shaped”, tubular structure, blind tube  No important digestive fnc. - digest cellulose  Appendicitis - inflammation Peritoneum -  Large, moist, slippery sheet of serous membrane  Peritoneal space - small space between parietal & visceral layers - surfaces slide freely  Retroperitoneal - organs outside peritoneum  Extensions of peritoneum-mesentary, greater omentum - both assist in anchoring abd. contents
  • 23.
    Digestion -Chemical &mechanical breakdown CHO - amylase in mouth, slight effect amylase from pancreas - into small intestine  Absorption of simple sugars (glucose) Proteins - stomach (HCL/pepsinogen> pepsin)  Finished in small intestine by pancreatic (trypsin) & peptidases in intestinal juice  Amino acids - basic protein units
  • 24.
    Fats - insmall intestine  Bile emulsification of fats > pancreatic lipase > fatty acids & glycerol Key digestive juices & enzymes * page 410 Table 15-2 Absorption - taking food, breaking it down in form for utilization of body Just as important as digestion

Editor's Notes

  • #4 Mucosa of esophagus- tough and stratified abrasion-resistant epithelium ****Mucosa of reminder of GI tract- delicate layer of simple columnar epithelium (absorption & secretion) *Mucus- coats the lining Submucosa- connective tissue, below the mucosa; contains large amounts of bld. vessels & nerves ***Muscularis- two layers of muscles: wavelike, rhythmic contraction of muscular coat> peristalsis Peristalsis: assists in the mixing of food> further mechanical breakdown of larger food particles Serosa- outermost covering of digestive tract ; composed of the visceral peritoneum * anchored to posterior wall with double fold of peritoneal tissue> mesentary
  • #6 ***Uvula & soft palate- prevent any food & liquid from entering the nasal cavities above the mouth
  • #8 Baby : 2 years old> full set of (20) baby teeth *first @ 6 months Deciduous Young adult: age 17-24 full set of permanent teeth (32) first @ 6 years Parts of the typical tooth: Crown: exposed/visable portion of tooth Hard tissue (enamel & dentin/cementum) Dentin- composed of tooth shell> center: pulp cavity consisting of connective tissue, blood & lymphatic vessels & sensory nerves Cementum- over the neck & root; NECK: surrounded by pink gingiva (gum tissue) ROOT: fits down into socket of upper/lower jaw; lined by the periodontal membrane**** * Orthodonist/Peridontist Clinical Application- Malocclusion page 482
  • #11 Provides active movement of food into the esophagus closing and sealing off the trachea Nasopharynx Oropharynx laryngeal pharynx The motor impulses from the swallowing act conroled by nervous stimulation of trigeminal, glossopharyneal, vagus, and hypoglossal cranial nerves
  • #12 *Contraction of the muscular walls mixes the food thoroughly with the gastric juice and breaks it down into a semisolid mixture called CHYME. ***Formation of CHYME: continuous of mechanical digestion> beginning in mouth Gastric juices: ***hydrochloric acid and enzymes that function in the digestive process Three layers of smooth muscles in the stomach wall: running lengthwise, around, and obliquely>>> one of the strongest internal organs of body>>able to break up the food into tiny particles > PERISTALSIS Peristalsis- propels food down the digestive tract Mucous membranes line stomach; contains thousands of microscopic gastric glands> HCL and gastric juice Internal folds of stomach : RUGAE *Intrinsic Factor- enables the absorption of Vit B-12; very important for blood cell formation > pernicious anemia
  • #15 Mucosa- small blood vessels, plasma, nerve cells, and blood cells Submucosa- large blood vessels, connective tissue, nerves, ganglia, and lymphactics VILLA- millions in number; “fingers” or folds projecting into the hallow interior of the intestine> rich with blood capillaries that absorb products of CHO/protein digestion ^ surface area for increased absorption ** Cryts of Lieberkunn- pitlike structures that lie in grooves between the villi & are composed of absorptive cells & mucous-producing goblet cells PH 7.0 ** Peyer’s patches_ lymphoid follicles> important in immune response; antibody synthesis Lacteal (lymph) > absorbs lipids or fatty materials from the chyme passing through the small intestines Approximately 8 liters of water q day is absorbed by the small intestines into the portal blood
  • #18 Control of secretions: vagal control & hormonal control Hormones: beta cells_ secrete insulin- utilization of glucose Alpha cells- secrete glucagon Enymes: trypsin- breaks down proteins Amylase- “”””’’ CHO tosimple sugars Lipase- breaks down trigylercides Pancreatitis- inflammation of pancreas blockage of common bile duct very serious/fata CF- lack of enyzme (too much and too thick pancratic enzymes) Cancer of pancreas- adenocarcinoma; life-span limited to around 5 years after diagnosis
  • #19 Flexures: 1) ***Hepatic: bend at the junction of the ascending and transverse colon; upper right quadrant of abd. 2) ***Splenic: bend at the juction of the transverse and descending colon; located at the left upper quadrant of abd. Vitamin K synthesis: essential (blood clotting) Normal passage of material through colon takes about 3-5 days Anus- inner/outer anal sphincter- straited/voluntary muscle(outer) inner - smooth/involuntary muscle> opens during defecation process Appenditis- inflammation of appendix; rupture > peritonitis: septecemia
  • #22 Ascites: abnormal accumulation of fluid in the peritoneal space Osmotic pressure problem (low plasma proteins) Accompanies> abdominal swelling, decreased urinary output CHF, cirrhosis, kidney disease, cancer, malnutrition