ChemAxon's Markush Editor assists you in all the steps of the Chemistry patent writing, saves time and effort, and helps create strong, high-quality claims. - Find the optimal scaffold and generate all R-group definitions automatically. - Hierarchical 'tree-like' visualization of R-group relationships in Markush structures - Real-time feedback about whether and how the compounds match the Markush structure - Generating Markush claims text and example structure list automatically in docx format

1. Writing Chemistry patents
Markush Editor - the New Way
Árpád Figyelmesi, Béla Pukánszky

2. Why Markush Claims are important
Between 1994 and 2013
3,704,996 US patents
468,262 with Markush claims
Every eighth patent contains
Markush claims
Markush claims often cover
>1010
structures

3. Patent Drafting as we know it
Manual process required
highly-skilled professionals
● Tedious
● Time consuming
● Error-prone

4. Writing patents
Finalization of the application
Claims drafting
Receive list of
new compounds
Identify Scaffold
Formulate
R-groups
Build up claim
hierarchy
Add list of
examples
Add detailed
description
Complete formal
requirements
File patent

5. PATENT DRAFTING -
MARKUSH EDITOR

6. Computer-Aided Patent Drafting
● Scaffold detection
● R-group formulation
● Interactive editing
● Search and visualization
● Draft generation

7. Markush Generation
Generate Markush structure from a series of compounds

8. Interactive Editor
R-group tree Validation view
Claim hierarchy
Example structure lists
Error checker
R-group editor

9. Safe and convenient editing
● Supports various input formats (SDF, CSV)
● Rich Markush functionality (R-groups, homologies,
position variation, repeating units, multipliers, etc.)
● Easily understandable, informative visualization
● Interactive validation against examples (or prior art)
● Immediate feedback about any inconsistencies or
drawing errors

10. Markush claims drafting
Generate English or Japanese claims

11. Exemplified structures list
Generate example list
● IUPAC names
● Structure images
Exported structures are editable in
MS Word with JChem for Office

12. CONCLUSION

13. Main benefits
A revolutionary new approach of chemistry patent drafting.
● Save time
● Avoid mistakes
● Check any structures against your parents easily
Better quality patents and competitive advantage in protecting your
IP rights.

14. Customers’ voice
“It saves days of work for us!”
(returning statement from several users)
● 15 customers worldwide
● 3 big pharma customers including Bayer
● 5+ ongoing evaluations

15. Ongoing developments
● Improved claim hierarchy creation and generalization workflow
● Automatic Markush generalization (e.g.: replace Cl with Halogen)
● Coverage analysis to help properly support all parts of the claims
with examples
● Export additional data (e.g.: ID, NMR, LD50
) to the draft document
● Various Composer and Markush to Text improvements