MIS applications are used in various industries like hospitals, hotels, banking, and manufacturing to support decision making under uncertainty. Hospital information systems integrate various components like clinical, financial, laboratory, and pharmacy systems to efficiently manage patient and administrative information. Hotel information systems provide benefits like improved performance, efficiency, control, and security. Decision making involves gathering information, identifying alternatives, evaluating choices, and selecting the best option to solve problems under uncertainty. Management information systems and decision support systems help managers in decision making processes.