Carlos Santos-Pérez is a biology student at the University of Puerto Rico-Cayey with a 4.0 GPA who is interested in pursuing a PhD in cancer biology; he has extensive research experience focusing on cancer and infectious disease through multiple research assistant positions; his goals are to obtain a PhD in cancer biology or cell biology and potentially pursue an MD/PhD.

1. Carlos Santos-Pérez
Urb Sierra Real Box 246
Cayey, PR 00736-9003
T 7873671030
carlos.santos9@upr.edu
carlossantos791@gmail.com
PROFILE
Innovation and critical thinking are two factors that motivate me to learn more in the
scientific research field. I am interested in all areas of science ranging from social science to
natural science. My strengths are that I am perseverant, responsible, a team member and hold
my self to a high standard. On the other hand, I recognize that I need to work on my
weaknesses.
E D U C AT I O N
Biology Student, University of Puerto Rico- Cayey (UPR-C) — 2010-2014
I am a biology major. Currently I am preparing for a Ph.D. in cancer biology. My GPA is
4.00 with 109 credits approved.
RESEARCH EXPERIENCE
Research Assistant, Dr. Richer Laboratory; The Endocrine Society - University of Colorado
— Summer 2011
My work focused on breast cancer research- 'MDV3100 as a Treatment for Luminal Breast
Cancer’. In order to perform this project I read scientific papers to understand completely the
procedures that I made in the laboratory (Real Time RT-PCR, Growth Assays,
Immunocytochemistry and Western Blot) In addition to that I read additional information in
order to understand the background information and the basic science behind this research
topic. Our aims were to determine if MDV3100 was an estrogen antagonist and how it was
able to inhibit the proliferation of the MCF7 cells (Luminal breast cancer cell line).
Research Assistant, Dr. Maldonado Laboratory; UPR-Cayey — August 2011 to May 2012
Using computational techniques we were looking for novel drugs to treat patients with
Dengue Virus. This project involved techniques related to bioinformatics, computational
biology and In silico drug discovery and development. Also I was able to learn how to design
molecules and to test if this molecules could be possible treatment against dengue virus. At
this point, potential possible treatments identified in our in silico approaches are going to be
tested in vitro.
Research Assistant, Dr. Shupnik Laboratory; The Endocrine Society- University of Virginia
— Summer 2012
I was working on a project called ‘Dax-1 and WT-1: Novel Regulators of the LHß
transcription’. Using Western Blot, Luciferase Assay and other techniques, we looked into
how these two proteins modulate the synthesis of the Luteinizing Hormone in conjunction
with the Gonadotropin Releasing Hormone and the proteasome degradation system of the

2. cell. Luteinizing Hormone over expression is associated with diseases like Polycystic Ovarian
Syndrome and other female reproduction endocrine disorders. Results from this research are
going to be publish next year.
Research Assistant, Dr. Maldonado Laboratory; UPR-Cayey — August 2012 to present
‘In silico drug discovery of Wee1 Kinase Inhibitors’ In this project we are identifying
potential drug-like compounds that may inhibit uncontrolled growth of cancer cells. Right
now, we are in the phase of finding potential protein targets associated with cancer
progression. It have been identified several targets associated with breast cancer, prostate
cancer and lung cancer.
HONORS
• First Place, Poster Presentation, 22nd Student Research Symposium at the University of
Puerto Rico at Cayey, September, 2011.
• Outstanding Presentation at ABRCMS meeting (Cancer Biology Category), November
2011.
• Outstanding Presentation at 23rd Student Research Symposium at the University of
Puerto Rico at Cayey, December 2011.
• First Place, Frank G. Brooks for Excellence in Student Research, Oral Presentation,
Caribbean Regional Convention National Biological Honor Society, March, 2012.
• Minority Access Program Award Recipient, The Endocrine Society April 2011.
• Honor Student of the HHH association at the University of Puerto Rico at Cayey.
• Outstanding Poster Presentation at ENDO 2012 (The Endocrine Society National
Conference) Minority Mentoring and Poster Reception, June 2012
• Outstanding Poster Presentation at SACNAS 2012, October 2012
• Award for Academic Excellence; Academic Affairs Dean’s Lists at the University of
Puerto Rico at Cayey, April 2011 and 2012.
P O S T E R P R E S E N TAT I O N S
22nd Student Research Symposium in the University of Puerto Rico at Cayey August,
2011.
Title presented: MDV3100 as a Treatment for Luminal Breast Cancer.

3. Annual Biomedical Research Conference for Minority Students (ABRCMS) 2011 November
2011
Title presented: MDV3100 as a Treatment for Luminal Breast Cancer
24th Student Research Symposium in the University of Puerto Rico at Cayey August,
2012
Title presented: Dax-1 and WT-1: Novel Regulators of the LHß transcription.
95th The Endocrine Society National Conference (ENDO 2012), June 2012
Title presented: MDV3100 as a Treatment for Luminal Breast Cancer.
Society for Advancement of Chicanos and Native Americans in Science (SACNAS) National
Conference, October 2012
Title presented: In silico Discovery of Dengue Virus Protease Inhibitors.
O R A L P R E S E N TAT I O N S
GEMS 2011; University of Colorado Denver, Anshutsz Medical Campus; Summer 2011.
Title Presented: MDV3100 as a Treatment for Luminal Breast Cancer.
23rd Student Research Symposium in the University of Puerto Rico at Cayey — December,
2011
Title Presented: In Silico Drug Discovery for Dengue Protease Inhibitors
Caribbean Regional Convention National Biological Honor Society at the University of
Puerto Rico at Cayey — March, 2012
Title Presented: MDV3100 as a Treatment for Luminal Breast Cancer
SRIP 2012 University of Virginia — August 2012
Title Presented: Dax 1 and WT 1: Novel Regulators of the LHß trasncription
PROFESSIONAL MEMBERSHIPS
Associate Member of The Endocrine Society
Attended to ENDO meetings of 2011 and 2012

4. National Biological Honor Society (Tri-Beta; Zeta Epsilon Chapter) at the University of
Puerto Rico at Cayey
Treasurer 2012-2013
HHH Honor Society Student Member of the University of Puerto Rico at Cayey
Society for Advancement of Chicanos and Native Americans in Science (SACNAS)
Student Member of American Association for Cancer Research (AACR)
FUTURE GOALS
PhD in Cancer Biology or Cell Biology
MD/PhD
REFERENCES
Steven Anderson PhD Margaret Shupnik PhD
Vice-Chair of Research, Senior Associate Dean for Research
University of Virginia
University of Colorado at Denver Dean’s office: (434) 982-3408
Phone: 303-724-3742 Lab office: (434)(82-0010
mas3x@virginia.edu
steve.anderson@ucdenver.edu