This document discusses using statistical physics, network theory, and big data to study human mobility. It outlines challenges in obtaining and analyzing large-scale mobility data from sources like smartphones and social media. The author proposes applying network-based modeling approaches inspired by statistical mechanics to build null models that generate predictions about mobility flows. Comparing these predictions to real data allows identifying abnormal patterns and validating hypotheses about key drivers of human movement like distance, population density, and opportunities. The goal is to better understand human mobility and distinguish important factors from negligible ones in an unbiased way.