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N.B II !N.B II !
By
Dr.Ahmed Alsherbiny
MSc. Ophth , FICO , FRCS Ophth (Glasg(
It is often wise to postpone intraocular surgery
till lacrimal infection has been treated, owing to
the grave risk of endophthalmitis
Hamartoma:
normal tissue
in normal place
with abnormal
configuration
Choristoma:
normal tissue
in abnormal
place
In pleomorphic lacrimal gland
adenoma , it is wise to avoid prior
biopsy, to avoid tumour seeding into
adjacent orbital tissue, with
recurrences which may later turn
malignant
Keratinazation of the curuncle is a
common early sign of mucous membrane
pemphigoid
In cogan syndrome , vestibulo-auditory
symptoms require immediate treatment with
systemic steroids to prevent hearing loss.
Management in conjunction with
otolaryngologist is essential;
immunosuppression may also be required
Unilateral arcus senilis is rare
entity that may be associated
with carotid disease or ocular
hypotony
Incidence of glaucoma:
1- primary open angle 1:100
2- primary closed angle 1:1000
3- congenital glaucoma 1:10000
The lens is the only ocular structure
which continues to increase in size
throughout life
Progressive enlargement of the corneal
diameter is as important sign of uncontrolled
congenital glaucoma as progressive visual
field loss is in adult glaucoma
10% of infants with congenital rubella
syndrome also have congenital glaucoma due to
angle anomaly similar to that in PCG. This
maybe missed because the eye may not
appear significantly enlarged, due to pre-
existing microphthalmos
Syphilis must be suspected in any
case of intraocular inflammation
resistant to conventional therapy
Metastatic tumours to the choroid are
more common than primary malignancies
In atypical CHRPE , you must exclude
Familial adenomatous polyposis
In racemose hemangioma, some patients have
similar ipsilateral lesions involving the midbrain,
baso-frontal region and posterior fossa
Ocacasionally, malformations may involve the
maxilla and mandible, predisposing the patient
to haemorrhage after dental treatment
Superior eye muscles (superior rectus &
superior oblique) are supplied by
conralateral nucleus
Evisceration does NOT seem to protect
against sympathetic ophthalmitis , It’s
Enucleation
In Sturge-Weber syndrome , Ipsilateral parietal
or occipital leptomeningeal haemangioma may
cause contralateral or generalized focal or
generalized seizers, hemiparesis or hemianopia
White Eyes with Increased IOP and
mild uveitis:
1-Prodroma of PCAG
2-Disciform Keratitis
3-Posner Schlossman syndrome
Pred Forte is a suspension eye drops ;
the patient must be instructed to shake
the bottle vigorously before use since
the active component of the preparation
will settle at the bottom of the bottle
and exert no effect
Steroid Responders:
1-Primary open angle glaucoma
patients
2-offspring of glaucoma patients
3-Myopia
4-Diabetics
5-Pigment dispersion syndrome
Beta blockers are
contraindicated with
digitalis or calcium channel
blockers
Alphagan is contraindicated
with MAO inhibitors and
children
In JIA associated uveitis , the eye
is uninjected even in the presence
of sever uveitis ; regular follow up
is very important
It is important always to consider
that exudative RD is caused by
intraocular tumour until proved
otherwise
In acoustic neuroma, the first symptom
is hearing loss and the first sign is
diminished corneal sensitivity
It is important to consider
retinoblastoma in the D.D of unusual
chronic uveitis in children
Malignancies with calcifications related to
the eye:
1-lacrimal gland carcinoma
2-retinoblastoma
3-optic nerve sheath meningioma
4-osseous choristoma
In Proptosis &
Ptosis ; Exclude
Psuedo presentation
first
In Glaucoma ,
Primary types is
diagnosed after
exclusion of
secondary causes
Myasthenia should be considered in the
differential diagnosis of any ocular
motility disorder that does not fit with
a recognized diagnosis
Posterior Segment diseases cause
photophobia:
1-Albinism
2-Progressive cone dystrophy
Mitochondrial Inheritence in
ophthalmology:
1-Kerns-Sayer syndrome
2-Leber hereditary optic
atrophy
Glaucoma with deep A.C:
1-Plateau iris syndrome
2-pigment dispersion syndrome
3-Buphthalmos
Lumbar Puncture in
ophthalmology:
1-M.S leucocytosis , igG > 15%
2-Refsum disease elevated CSF
proteins , no pleocutosis
3-Retinoblastoma increased pressure in
trilateral retinoblatoma & detection of metastasis
4-Vogt Koyanagi Harada
Disease pleocytosis with small lymphocytes
5-Idiopathic intracranial
hypertension increased pressure
6-Kearns Sayer syndrome
increased CSF proteins >1g/l
Thank You

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N.B II !

  • 1. N.B II !N.B II ! By Dr.Ahmed Alsherbiny MSc. Ophth , FICO , FRCS Ophth (Glasg(
  • 2. It is often wise to postpone intraocular surgery till lacrimal infection has been treated, owing to the grave risk of endophthalmitis
  • 3. Hamartoma: normal tissue in normal place with abnormal configuration Choristoma: normal tissue in abnormal place
  • 4. In pleomorphic lacrimal gland adenoma , it is wise to avoid prior biopsy, to avoid tumour seeding into adjacent orbital tissue, with recurrences which may later turn malignant
  • 5. Keratinazation of the curuncle is a common early sign of mucous membrane pemphigoid
  • 6. In cogan syndrome , vestibulo-auditory symptoms require immediate treatment with systemic steroids to prevent hearing loss. Management in conjunction with otolaryngologist is essential; immunosuppression may also be required
  • 7. Unilateral arcus senilis is rare entity that may be associated with carotid disease or ocular hypotony
  • 8. Incidence of glaucoma: 1- primary open angle 1:100 2- primary closed angle 1:1000 3- congenital glaucoma 1:10000
  • 9. The lens is the only ocular structure which continues to increase in size throughout life
  • 10. Progressive enlargement of the corneal diameter is as important sign of uncontrolled congenital glaucoma as progressive visual field loss is in adult glaucoma
  • 11. 10% of infants with congenital rubella syndrome also have congenital glaucoma due to angle anomaly similar to that in PCG. This maybe missed because the eye may not appear significantly enlarged, due to pre- existing microphthalmos
  • 12. Syphilis must be suspected in any case of intraocular inflammation resistant to conventional therapy
  • 13. Metastatic tumours to the choroid are more common than primary malignancies
  • 14. In atypical CHRPE , you must exclude Familial adenomatous polyposis
  • 15. In racemose hemangioma, some patients have similar ipsilateral lesions involving the midbrain, baso-frontal region and posterior fossa Ocacasionally, malformations may involve the maxilla and mandible, predisposing the patient to haemorrhage after dental treatment
  • 16. Superior eye muscles (superior rectus & superior oblique) are supplied by conralateral nucleus
  • 17. Evisceration does NOT seem to protect against sympathetic ophthalmitis , It’s Enucleation
  • 18. In Sturge-Weber syndrome , Ipsilateral parietal or occipital leptomeningeal haemangioma may cause contralateral or generalized focal or generalized seizers, hemiparesis or hemianopia
  • 19. White Eyes with Increased IOP and mild uveitis: 1-Prodroma of PCAG 2-Disciform Keratitis 3-Posner Schlossman syndrome
  • 20. Pred Forte is a suspension eye drops ; the patient must be instructed to shake the bottle vigorously before use since the active component of the preparation will settle at the bottom of the bottle and exert no effect
  • 21. Steroid Responders: 1-Primary open angle glaucoma patients 2-offspring of glaucoma patients 3-Myopia 4-Diabetics 5-Pigment dispersion syndrome
  • 22. Beta blockers are contraindicated with digitalis or calcium channel blockers Alphagan is contraindicated with MAO inhibitors and children
  • 23. In JIA associated uveitis , the eye is uninjected even in the presence of sever uveitis ; regular follow up is very important
  • 24. It is important always to consider that exudative RD is caused by intraocular tumour until proved otherwise
  • 25. In acoustic neuroma, the first symptom is hearing loss and the first sign is diminished corneal sensitivity
  • 26. It is important to consider retinoblastoma in the D.D of unusual chronic uveitis in children
  • 27. Malignancies with calcifications related to the eye: 1-lacrimal gland carcinoma 2-retinoblastoma 3-optic nerve sheath meningioma 4-osseous choristoma
  • 28. In Proptosis & Ptosis ; Exclude Psuedo presentation first In Glaucoma , Primary types is diagnosed after exclusion of secondary causes
  • 29. Myasthenia should be considered in the differential diagnosis of any ocular motility disorder that does not fit with a recognized diagnosis
  • 30. Posterior Segment diseases cause photophobia: 1-Albinism 2-Progressive cone dystrophy
  • 31. Mitochondrial Inheritence in ophthalmology: 1-Kerns-Sayer syndrome 2-Leber hereditary optic atrophy
  • 32. Glaucoma with deep A.C: 1-Plateau iris syndrome 2-pigment dispersion syndrome 3-Buphthalmos
  • 33. Lumbar Puncture in ophthalmology: 1-M.S leucocytosis , igG > 15% 2-Refsum disease elevated CSF proteins , no pleocutosis 3-Retinoblastoma increased pressure in trilateral retinoblatoma & detection of metastasis 4-Vogt Koyanagi Harada Disease pleocytosis with small lymphocytes 5-Idiopathic intracranial hypertension increased pressure 6-Kearns Sayer syndrome increased CSF proteins >1g/l