This document compares and contrasts spreadsheets and relational databases for managing data. Spreadsheets are grids that organize data into cells and allow for calculations. They are simple to use but can contain repeated data and errors. Relational databases store data in tables that can be linked to reduce duplication. They eliminate repeated data through these links but are more difficult to set up. The document outlines examples of using each and highlights advantages and disadvantages of spreadsheets and databases.