This document discusses key challenges facing African agriculture, including poor policies, rising population, low technology generation and adoption, poor soil fertility, and climate change. It then summarizes Mohammed VI Polytechnic University's (UM6P) efforts to address these challenges through applied research, innovation, entrepreneurship, capacity building, knowledge generation and sharing, stakeholder engagement, and climate-oriented initiatives. UM6P follows a demand-driven training approach, starting with faculty and researchers, and then potential PhD and master's candidates, to build local and African agricultural capacity.