This document provides guidance on monitoring, evaluation, and learning (MEL) for organizations working with USAID. It outlines why MEL is important to support effective implementation, accountability, and decision-making. Key elements of a strong MEL system include developing indicators to track progress, ensuring high quality data, supporting evaluations, and applying lessons learned through collaboration and adaptation. The document provides recommendations on what to include in a MEL plan and how to structure MEL personnel, processes, and reporting.