Non-gonococcal bacterial arthritis is a dangerous form of acute monoarthritis that can destroy cartilage within days. It typically presents as pain and swelling in a large joint like the knee. A diagnosis requires joint aspiration to obtain synovial fluid for cell count, microscopy and culture since symptoms like fever may be absent and tests such as blood tests are non-specific. Common organisms include Staphylococcus and Streptococcus. Treatment involves antibiotics like flucloxicillin for 2-6 weeks as well as joint drainage through needle aspiration or surgery. Outcomes depend on host factors, virulence of the organism, and speed of initiating effective treatment.
Psoriasis is a common skin condition characterized by red, scaly skin patches that are usually found on the scalp, elbows and knees, and may be associated with joint pain and stiffness. It is caused by an immune system disorder and is influenced by genetic and environmental factors. Treatment options include topical creams and ointments, oral medications, light therapy, and management of flare-ups through control of triggers like stress, smoking, and alcohol use.
La psoriasis es una enfermedad inmunomediada crónica de la piel causada por la activación anormal de linfocitos T. Se cree que los linfocitos T de memoria CD45RO+ son los principales mediadores de la enfermedad. Los tratamientos actuales incluyen fármacos tópicos y sistémicos que actúan suprimiendo la actividad de los linfocitos T para reducir los síntomas e inducir la remisión.
This document summarizes information about psoriasis, including its epidemiology, genetics, clinical presentations, pathogenesis, and relationship to cardiovascular disease risk factors. Some key points:
- Psoriasis prevalence varies globally, from 0.05-4.7% depending on the population. Genetic factors play a role in its development and susceptibility loci have been identified.
- Clinical presentations include plaque, guttate, pustular, erythrodermic, and nail psoriasis. Psoriatic arthritis affects 5-8% of patients.
- Psoriasis is considered a T-cell mediated immune disease involving Th1 and Th17 responses and inflammatory cytokines like TNF-
La psoriasis es una enfermedad inflamatoria crónica de la piel que produce lesiones escamosas e inflamadas. Se estima que entre el 1 y 3% de la población la padece, y puede aparecer a cualquier edad aunque suele hacerlo entre los 15 y 35 años. Tiene una etiología multifactorial relacionada con factores genéticos y ambientales como traumatismos, infecciones, fármacos, estrés y factores climáticos. Existen varios tipos de psoriasis según la morfología
This document summarizes psoriasis, including its epidemiology, etiology, pathogenesis, diagnosis, clinical features, and treatment. Psoriasis is a chronic inflammatory skin condition that affects about 2-3% of the population. It is caused by genetic and environmental factors that trigger an immune response resulting in increased skin cell turnover. Diagnosis is usually based on appearance of red, scaly plaques. Treatment includes topical therapies like corticosteroids and vitamin D analogues as well as phototherapy and systemic drugs for more severe cases.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes symmetrical joint inflammation. It affects around 1% of the population, predominantly women aged 30-50. Genetic and environmental factors contribute to its development. RA is characterized by synovitis and infiltration of inflammatory cells into the synovium, resulting in cartilage and bone destruction. Common clinical features include pain, stiffness, and swelling of small joints. Left untreated, RA can cause joint deformity and damage to other body systems. Investigations reveal elevated inflammatory markers and autoantibodies. Management involves a multidisciplinary approach including medications to relieve symptoms and slow disease progression.
The document discusses psoriasis, including its epidemiology, pathophysiology, clinical presentations, diagnosis, differential diagnosis, and management. Psoriasis is a chronic, inflammatory skin condition characterized by red scaly plaques. It has a genetic component and can be triggered by various environmental factors. Clinical diagnosis is usually based on appearance of lesions. Topical therapies are first-line treatment for mild-moderate disease, while phototherapy and systemic therapies may be used for more severe cases. Proper management requires a tailored approach based on individual disease characteristics and goals of improving quality of life and long-term disease control.
แนวทางเวชปฏิบัติการรักษาโรคข้อเข่าเสื่อม
(Guideline for the Treatment of Osteoarthritis of Knee)
โดย
สมาคมรูมาติสซั่มแห่งประเทศไทย พ.ศ. 2553
แหล่งข้อมูล:
http://www.thairheumatology.org/attchfile/OA%20knee%20guideline.pdf
Non-gonococcal bacterial arthritis is a dangerous form of acute monoarthritis that can destroy cartilage within days. It typically presents as pain and swelling in a large joint like the knee. A diagnosis requires joint aspiration to obtain synovial fluid for cell count, microscopy and culture since symptoms like fever may be absent and tests such as blood tests are non-specific. Common organisms include Staphylococcus and Streptococcus. Treatment involves antibiotics like flucloxicillin for 2-6 weeks as well as joint drainage through needle aspiration or surgery. Outcomes depend on host factors, virulence of the organism, and speed of initiating effective treatment.
Psoriasis is a common skin condition characterized by red, scaly skin patches that are usually found on the scalp, elbows and knees, and may be associated with joint pain and stiffness. It is caused by an immune system disorder and is influenced by genetic and environmental factors. Treatment options include topical creams and ointments, oral medications, light therapy, and management of flare-ups through control of triggers like stress, smoking, and alcohol use.
La psoriasis es una enfermedad inmunomediada crónica de la piel causada por la activación anormal de linfocitos T. Se cree que los linfocitos T de memoria CD45RO+ son los principales mediadores de la enfermedad. Los tratamientos actuales incluyen fármacos tópicos y sistémicos que actúan suprimiendo la actividad de los linfocitos T para reducir los síntomas e inducir la remisión.
This document summarizes information about psoriasis, including its epidemiology, genetics, clinical presentations, pathogenesis, and relationship to cardiovascular disease risk factors. Some key points:
- Psoriasis prevalence varies globally, from 0.05-4.7% depending on the population. Genetic factors play a role in its development and susceptibility loci have been identified.
- Clinical presentations include plaque, guttate, pustular, erythrodermic, and nail psoriasis. Psoriatic arthritis affects 5-8% of patients.
- Psoriasis is considered a T-cell mediated immune disease involving Th1 and Th17 responses and inflammatory cytokines like TNF-
La psoriasis es una enfermedad inflamatoria crónica de la piel que produce lesiones escamosas e inflamadas. Se estima que entre el 1 y 3% de la población la padece, y puede aparecer a cualquier edad aunque suele hacerlo entre los 15 y 35 años. Tiene una etiología multifactorial relacionada con factores genéticos y ambientales como traumatismos, infecciones, fármacos, estrés y factores climáticos. Existen varios tipos de psoriasis según la morfología
This document summarizes psoriasis, including its epidemiology, etiology, pathogenesis, diagnosis, clinical features, and treatment. Psoriasis is a chronic inflammatory skin condition that affects about 2-3% of the population. It is caused by genetic and environmental factors that trigger an immune response resulting in increased skin cell turnover. Diagnosis is usually based on appearance of red, scaly plaques. Treatment includes topical therapies like corticosteroids and vitamin D analogues as well as phototherapy and systemic drugs for more severe cases.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes symmetrical joint inflammation. It affects around 1% of the population, predominantly women aged 30-50. Genetic and environmental factors contribute to its development. RA is characterized by synovitis and infiltration of inflammatory cells into the synovium, resulting in cartilage and bone destruction. Common clinical features include pain, stiffness, and swelling of small joints. Left untreated, RA can cause joint deformity and damage to other body systems. Investigations reveal elevated inflammatory markers and autoantibodies. Management involves a multidisciplinary approach including medications to relieve symptoms and slow disease progression.
The document discusses psoriasis, including its epidemiology, pathophysiology, clinical presentations, diagnosis, differential diagnosis, and management. Psoriasis is a chronic, inflammatory skin condition characterized by red scaly plaques. It has a genetic component and can be triggered by various environmental factors. Clinical diagnosis is usually based on appearance of lesions. Topical therapies are first-line treatment for mild-moderate disease, while phototherapy and systemic therapies may be used for more severe cases. Proper management requires a tailored approach based on individual disease characteristics and goals of improving quality of life and long-term disease control.
แนวทางเวชปฏิบัติการรักษาโรคข้อเข่าเสื่อม
(Guideline for the Treatment of Osteoarthritis of Knee)
โดย
สมาคมรูมาติสซั่มแห่งประเทศไทย พ.ศ. 2553
แหล่งข้อมูล:
http://www.thairheumatology.org/attchfile/OA%20knee%20guideline.pdf