Professor Sir Mike Richards CBE, Director for Preventing Early Deaths at the NHS Commissioning Board, looks back at the NHS in the 1990s to see how much progress has been made in improving health outcomes since then.
Dick Sorabji: Providing the evidence base for integrated careThe King's Fund
Dick Sorabji, Corporate Director of Policy and Public Affairs, London Councils, shares examples of integrated care initiatives in London and looks at the future barriers to achieving integration.
Katrina Percy: Working with partners to deliver high quality health and socia...The King's Fund
Katrina Percy, Chief Executive of Southern Health NHS Foundation Trust, talks about the health system in Hampshire and the key elements of Southern Health’s integrated care strategy.
Jay Crosson on integrated care - lessons from the USThe King's Fund
This document discusses delivery system reform and accountable care organizations (ACOs) in the United States healthcare system. It provides context on the rationale for delivery system reform to control escalating costs. It then discusses ACOs as a model for structural and payment changes that can improve care delivery and costs. Examples of established ACOs and barriers to forming new ACOs are also summarized.
Anne Eden, Chief Executive, Buckinghamshire Healthcare NHS Trust, explores the role that hospitals can play in delivering integrated care. Using examples of her team's work in Buckinghamshire, including their integrated stroke programme, she highlights the benefits to patients and the value of developing an integrated care pathway.
The document discusses different approaches to teaching statistics to psychology students and evaluating existing open educational resources (OERs) for teaching statistics. It notes that statistics is difficult for psychology students to understand and different students learn in different ways. It proposes classifying existing OERs by their teaching approach and having students self-assess samples to find what works best for their learning style. It also discusses evaluating learning style assessments and coding the best ones into the OpenLearn platform. Finally, it identifies some existing statistics teaching resources and notes that peer-reviewed sites like Merlot are better for evaluating quality.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
The document outlines the schedule for breakout sessions on Thursday with topics around using apps and digital technologies to support mental health, video conferencing for consultations, engaging staff and users in digital services, encouraging self-management of long-term conditions, delivering healthcare in rural settings, and training staff on technology adoption. The breakout sessions consist of multiple presentations on these topics from professionals in the health and technology fields.
Dick Sorabji: Providing the evidence base for integrated careThe King's Fund
Dick Sorabji, Corporate Director of Policy and Public Affairs, London Councils, shares examples of integrated care initiatives in London and looks at the future barriers to achieving integration.
Katrina Percy: Working with partners to deliver high quality health and socia...The King's Fund
Katrina Percy, Chief Executive of Southern Health NHS Foundation Trust, talks about the health system in Hampshire and the key elements of Southern Health’s integrated care strategy.
Jay Crosson on integrated care - lessons from the USThe King's Fund
This document discusses delivery system reform and accountable care organizations (ACOs) in the United States healthcare system. It provides context on the rationale for delivery system reform to control escalating costs. It then discusses ACOs as a model for structural and payment changes that can improve care delivery and costs. Examples of established ACOs and barriers to forming new ACOs are also summarized.
Anne Eden, Chief Executive, Buckinghamshire Healthcare NHS Trust, explores the role that hospitals can play in delivering integrated care. Using examples of her team's work in Buckinghamshire, including their integrated stroke programme, she highlights the benefits to patients and the value of developing an integrated care pathway.
The document discusses different approaches to teaching statistics to psychology students and evaluating existing open educational resources (OERs) for teaching statistics. It notes that statistics is difficult for psychology students to understand and different students learn in different ways. It proposes classifying existing OERs by their teaching approach and having students self-assess samples to find what works best for their learning style. It also discusses evaluating learning style assessments and coding the best ones into the OpenLearn platform. Finally, it identifies some existing statistics teaching resources and notes that peer-reviewed sites like Merlot are better for evaluating quality.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
The document outlines the schedule for breakout sessions on Thursday with topics around using apps and digital technologies to support mental health, video conferencing for consultations, engaging staff and users in digital services, encouraging self-management of long-term conditions, delivering healthcare in rural settings, and training staff on technology adoption. The breakout sessions consist of multiple presentations on these topics from professionals in the health and technology fields.
John Appleby: Health spending in the EU - how does the UK compare?The King's Fund
John Appleby, Chief Economist at The King's Fund, looks at how health spending in the UK compares with other countries and what the prospects are for spending on health care beyond 2015.
KESW2012 Linked Data for Enterprises and Governments (5 Oct 2012)AI4BD GmbH
The document summarizes a presentation on Linked Data given at KESW school on October 5, 2012 in St. Petersburg. The morning session included talks on the evolution of Linked Open Data, its current status and challenges, and the LOD lifecycle. The afternoon session covered using Linked Data for enterprises and included case studies. Hands-on sessions on working with LOD were also part of the agenda. The objectives of the presentation were to understand the basic concepts of LOD, how to publish and consume LOD, relevant tools and use cases, and benefits and limitations.
Robert Chote: Public finances and health careThe King's Fund
Robert Chote, Chairman of the Office for Budget Responsibility (OBR), shares the results of the OBR’s 2012 Fiscal Sustainability report, with a specific focus on health care spending.
David Oliver: designing services that are age appropriateThe King's Fund
David Oliver, Visiting Fellow at The King’s Fund, looks at the challenges around providing health care for an ageing population, and the solutions to achieving better joined-up care.
The document discusses the origins of online video as a new business model, tracing it back to Apple Computer releasing high quality weekly video trailers in the late 1990s. As DSL connections and speeds increased in the early 2000s, more tech startups emerged in Silicon Valley, including Google. YouTube later became popular due to offering larger, higher resolution copyright-free videos and using viral marketing techniques, appealing to consumers rather than just producers. The key was providing a large amount and variety of videos rather than high image quality alone.
Clive Bowman: The future for residential care provisionThe King's Fund
Clive Bowman, Medical Director, Bupa Care Homes, gives a history of care homes in England and looks at the challenges facing residential care provision in the future.
Simon Cunningham: How the Safer Births Programme has made a difference to qua...The King's Fund
The Safer Births Programme made improvements to maternity care at MCHT Crewe over time. Key changes included implementing tools like SBAR for better communication, a buddy system for hourly CTG reviews, and a birthrate acuity tool for escalation. These helped increase teamwork and coordination. Outcomes included higher ratings for safety culture, fewer CTG misinterpretations, and decreased rates of low cord gases and postpartum hemorrhage. Lessons included involving staff earlier and maintaining momentum with continued initiatives to further normalize safe practices.
Improving the Quality of Care in General PracticeThe King's Fund
Dr Nick Goodwin, Project Director and Senior Fellow at The King's Fund, talks about the main findings from the independent Inquiry into the Quality of General Practice in England.
David Buck on improving the allocation of health resources in England The King's Fund
David Buck, Senior Fellow in Public Health and Inequalities at The King’s Fund, explains how health resources are allocated in the English NHS, and how improvements to the process could be made to support a more coherent health and care system.
Improving health and health care in London: Who will take the lead?The King's Fund
John Appleby introduces The King's Fund's report on health and health care in London, considering who will lead improvements and reform after Healthcare for London.
Coqtail is a digital concept and technology agency based in Amsterdam that provides creative marketing and technology solutions. They work with clients in the fashion and lifestyle industries to create smart solutions and drive sales through advertising, app building, branding, and more. Coqtail was founded in 2011 and now has a team of 16 people who work with clients such as Nubbik, The Garment Club, and Lindenhoff.
This document summarizes a presentation about transforming the web together through open data and standards. It discusses the World Wide Web Consortium (W3C) and its role in developing open web standards. It provides examples of linked open data projects including data.gov and mashups of government data. Specific open data portals for cities like Chicago are highlighted. Semantic web technologies like RDF, RDFa, and SPARQL are referenced as working groups at W3C. Links are included to further resources on linked open data basics and news portals. The presentation concludes with mentioning Peter Mika from Yahoo discussing open data.
Lynda Bull: Providing joint services across the public sectorThe King's Fund
Lynda Bull, Corporate Director, Community Wellbeing for Milton Keynes Council talks about providing joint services across the public sector at The King's Fund Annual Conference 2010.
Liz Bruce: Manchester health and wellbeing boardThe King's Fund
Liz Bruce talks through how Manchester health and wellbeing board promotes partnership across local government, public health, the local NHS and third sector.
Understanding NHS financial pressures: visual resourcesThe King's Fund
This slideset contains key visual elements from our report, Understanding NHS financial pressures: how are they affecting patient care? Please feel free to share and re-use these graphics with credit to The King's Fund.
Nine characteristics of good-quality care in district nursing taken from interviews with patients, carers and staff.
We hope this framework and these slides will be a useful resource for you – please feel free to use them in your work, in documents and presentations.
John Appleby: Health spending in the EU - how does the UK compare?The King's Fund
John Appleby, Chief Economist at The King's Fund, looks at how health spending in the UK compares with other countries and what the prospects are for spending on health care beyond 2015.
KESW2012 Linked Data for Enterprises and Governments (5 Oct 2012)AI4BD GmbH
The document summarizes a presentation on Linked Data given at KESW school on October 5, 2012 in St. Petersburg. The morning session included talks on the evolution of Linked Open Data, its current status and challenges, and the LOD lifecycle. The afternoon session covered using Linked Data for enterprises and included case studies. Hands-on sessions on working with LOD were also part of the agenda. The objectives of the presentation were to understand the basic concepts of LOD, how to publish and consume LOD, relevant tools and use cases, and benefits and limitations.
Robert Chote: Public finances and health careThe King's Fund
Robert Chote, Chairman of the Office for Budget Responsibility (OBR), shares the results of the OBR’s 2012 Fiscal Sustainability report, with a specific focus on health care spending.
David Oliver: designing services that are age appropriateThe King's Fund
David Oliver, Visiting Fellow at The King’s Fund, looks at the challenges around providing health care for an ageing population, and the solutions to achieving better joined-up care.
The document discusses the origins of online video as a new business model, tracing it back to Apple Computer releasing high quality weekly video trailers in the late 1990s. As DSL connections and speeds increased in the early 2000s, more tech startups emerged in Silicon Valley, including Google. YouTube later became popular due to offering larger, higher resolution copyright-free videos and using viral marketing techniques, appealing to consumers rather than just producers. The key was providing a large amount and variety of videos rather than high image quality alone.
Clive Bowman: The future for residential care provisionThe King's Fund
Clive Bowman, Medical Director, Bupa Care Homes, gives a history of care homes in England and looks at the challenges facing residential care provision in the future.
Simon Cunningham: How the Safer Births Programme has made a difference to qua...The King's Fund
The Safer Births Programme made improvements to maternity care at MCHT Crewe over time. Key changes included implementing tools like SBAR for better communication, a buddy system for hourly CTG reviews, and a birthrate acuity tool for escalation. These helped increase teamwork and coordination. Outcomes included higher ratings for safety culture, fewer CTG misinterpretations, and decreased rates of low cord gases and postpartum hemorrhage. Lessons included involving staff earlier and maintaining momentum with continued initiatives to further normalize safe practices.
Improving the Quality of Care in General PracticeThe King's Fund
Dr Nick Goodwin, Project Director and Senior Fellow at The King's Fund, talks about the main findings from the independent Inquiry into the Quality of General Practice in England.
David Buck on improving the allocation of health resources in England The King's Fund
David Buck, Senior Fellow in Public Health and Inequalities at The King’s Fund, explains how health resources are allocated in the English NHS, and how improvements to the process could be made to support a more coherent health and care system.
Improving health and health care in London: Who will take the lead?The King's Fund
John Appleby introduces The King's Fund's report on health and health care in London, considering who will lead improvements and reform after Healthcare for London.
Coqtail is a digital concept and technology agency based in Amsterdam that provides creative marketing and technology solutions. They work with clients in the fashion and lifestyle industries to create smart solutions and drive sales through advertising, app building, branding, and more. Coqtail was founded in 2011 and now has a team of 16 people who work with clients such as Nubbik, The Garment Club, and Lindenhoff.
This document summarizes a presentation about transforming the web together through open data and standards. It discusses the World Wide Web Consortium (W3C) and its role in developing open web standards. It provides examples of linked open data projects including data.gov and mashups of government data. Specific open data portals for cities like Chicago are highlighted. Semantic web technologies like RDF, RDFa, and SPARQL are referenced as working groups at W3C. Links are included to further resources on linked open data basics and news portals. The presentation concludes with mentioning Peter Mika from Yahoo discussing open data.
Lynda Bull: Providing joint services across the public sectorThe King's Fund
Lynda Bull, Corporate Director, Community Wellbeing for Milton Keynes Council talks about providing joint services across the public sector at The King's Fund Annual Conference 2010.
Liz Bruce: Manchester health and wellbeing boardThe King's Fund
Liz Bruce talks through how Manchester health and wellbeing board promotes partnership across local government, public health, the local NHS and third sector.
Understanding NHS financial pressures: visual resourcesThe King's Fund
This slideset contains key visual elements from our report, Understanding NHS financial pressures: how are they affecting patient care? Please feel free to share and re-use these graphics with credit to The King's Fund.
Nine characteristics of good-quality care in district nursing taken from interviews with patients, carers and staff.
We hope this framework and these slides will be a useful resource for you – please feel free to use them in your work, in documents and presentations.
Suitable housing is essential for personal well-being and quality of life at all stages of life. It enables access to services, social relationships, and independence. Housing associations play an important role in supporting health by providing suitable accommodation and programs that prevent falls, reduce isolation, and encourage healthy behaviors, especially for older residents and those with disabilities or long-term conditions. Through adaptations, supportive housing, and care services, they can help people maintain independence and avoid expensive acute health services.
District councils’ contribution to public healthThe King's Fund
Our health is primarily determined by factors beyond just
health care. These slides illustrate the ways in which district
councils influence the health of local people through their key
functions and in their wider role supporting communities and
influencing other bodies.
The King’s Fund Events organise more than 20 health and social care events each year. Our highly-regarded conferences attract leading speakers from the government, the NHS, local authorities and the independent and voluntary sectors.
Jos de Blok set up Buurtzorg – which means ‘neighbourhood care’ in Dutch – with a team of four nurses. Today there are nearly 8,000 Buurtzorg nurses in 630 independent teams, caring for 60,000 patients a year. Nurses in Sweden, Norway, Japan and the United States are adopting the Buurtzorg model.
While women currently make up 44% of registered doctors in the UK, they are underrepresented in medical leadership roles, with only 24% of trust medical directors being women. Although 55% of medical students are now women, indicating they will likely become the majority of the medical workforce in the next decade, women currently account for just 32% of consultants compared to 54% of trainee doctors. Research has identified barriers for women progressing into leadership, such as work-life balance, organizational cultures, and personal expectations.
Our infographics highlight some key facts and figures around leadership vacancies in the NHS and some of the difficulties NHS organisations face in recruiting and retaining people for executive positions.
Sharing leadership with patients and users: a roundtable discussionThe King's Fund
‘What more is possible when patients, service users and those delivering services share the leadership task in health and social care?’
We held a roundtable discussion with patient leaders and organisational leads to discuss this question. Our slidepack summaries the conversations, including the opportunities and challenges for patient leaders, and where and how to start shared leadership working.
Making the case for public health interventionsThe King's Fund
In partnership with the Local Government Association, we have produced a set of infographics that describe key facts about the public health system and the return on investment for some public health interventions.
We hope they will be a useful resource for you – please feel free to use them in your office, in documents or presentations.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
The document outlines the schedule for breakout sessions on Thursday with various presentations grouped into six tracks:
Track T4A focuses on telemonitoring services and mobile health tools to engage patients. Track T4B looks at tackling social isolation in older people through digital advocates and technology. Track T4C examines integrating systems across multiple teams and platforms to provide personalized care. Track T4D analyzes using social media to better communicate care coordination and relationships between patients and providers. Track T4E explores supporting access to primary care through digital healthcare kiosks and online access. Finally, Track T4F discusses digitally sharing clinical information through a mobile workforce and connecting data, systems and citizens.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
The document outlines the schedule for breakout sessions on Thursday. It lists 6 sessions (T4A through T4F) with 3 presentations each. The presentations will cover topics like using telemonitoring to support those with long-term conditions, tackling social isolation in older people, integrating systems across teams and platforms, using social media to facilitate communication, supporting access to primary care, and digitally sharing clinical information. Speakers include professionals from universities, healthcare organizations, and technology companies.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
The document outlines the schedule for breakout sessions on Thursday at a conference. It lists 6 concurrent sessions (T2A through T2F) happening during session two. Each session has multiple presentations on topics related to digital health and care, such as apps to help with mental health, using video conferencing for consultations, engaging staff and users to adopt digital services, encouraging self-management of long-term conditions, delivering healthcare in rural settings, and training staff on technology. The document provides the names and affiliations of the multiple speakers at each breakout session.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
The document outlines the schedule for breakout sessions on Thursday of a conference. It lists 6 concurrent sessions (T2A through T2F) with multiple presentations in each session. The presentations discuss using apps and digital technologies to help people with mental health issues, facilitate e-consultations using video conferencing, engage staff and users in adopting digital services, encourage self-management of long-term conditions, deliver healthcare in rural settings, and ensure training and adoption of technology by staff.
International digital health and care congress 2014 - Breakouts: Friday, Sess...The King's Fund
This document outlines the schedule for breakout sessions on Friday with various presentations on delivering healthcare through digital means. Session Three includes breakout groups on topics like using digital services to support care planning and caregiving, demonstrating remote monitoring technologies, delivering therapy online, exploring barriers to telehealth adoption, digital support for rehabilitation and activity, and lessons from adopting paperless medical records. The sessions will feature presentations from various healthcare professionals, researchers, and technology companies on their work utilizing digital tools and telehealth.
International digital health and care congress 2014 - Breakouts: Thursday, se...The King's Fund
This document outlines the schedule for breakout sessions on Thursday. It lists 6 sessions (T4A through T4F) with multiple presentations and speakers in each session. The sessions cover topics like telemonitoring services, tackling social isolation, integrating systems across platforms, using social media to facilitate communication, supporting access to primary care, and digitally sharing clinical information.
The document summarizes the findings and recommendations of the Commission on the Future of Health and Social Care in England. It identifies three key problems with the current system: it is unfair, funding is separate between health and social care, and services are not well coordinated. The Commission recommends a new system that 1) commissions health and social care together, 2) simplifies access and increases personal control, and 3) increases free social care provision over time. However, these changes would require more funding. The Commission believes the costs can be covered through tax increases focused on those who can afford to pay more, and that the reformed system would be more efficient and achieve better outcomes.
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Spontaneous Bacterial Peritonitis - Pathogenesis , Clinical Features & Manage...Jim Jacob Roy
In this presentation , SBP ( spontaneous bacterial peritonitis ) , which is a common complication in patients with cirrhosis and ascites is described in detail.
The reference for this presentation is Sleisenger and Fordtran's Gastrointestinal and Liver Disease Textbook ( 11th edition ).
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Applications of NMR in Protein Structure Prediction.pptxAnagha R Anil
This presentation explores the pivotal role of Nuclear Magnetic Resonance (NMR) spectroscopy in predicting protein structures. It delves into the methodologies, advancements, and applications of NMR in determining the three-dimensional configurations of proteins, which is crucial for understanding their function and interactions.
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14...Donc Test
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
Can Traditional Chinese Medicine Treat Blocked Fallopian Tubes.pptxFFragrant
There are many traditional Chinese medicine therapies to treat blocked fallopian tubes. And herbal medicine Fuyan Pill is one of the more effective choices.
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
- Video recording of this lecture in English language: https://youtu.be/RvdYsTzgQq8
- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Selective alpha1 blockers are Prazosin, Terazosin, Doxazosin, Tamsulosin and Silodosin majorly used to treat BPH, also hypertension, PTSD, Raynaud's phenomenon, CHF
CLASSIFICATION OF H1 ANTIHISTAMINICS-
FIRST GENERATION ANTIHISTAMINICS-
1)HIGHLY SEDATIVE-DIPHENHYDRAMINE,DIMENHYDRINATE,PROMETHAZINE,HYDROXYZINE 2)MODERATELY SEDATIVE- PHENARIMINE,CYPROHEPTADINE, MECLIZINE,CINNARIZINE
3)MILD SEDATIVE-CHLORPHENIRAMINE,DEXCHLORPHENIRAMINE
TRIPROLIDINE,CLEMASTINE
SECOND GENERATION ANTIHISTAMINICS-FEXOFENADINE,
LORATADINE,DESLORATADINE,CETIRIZINE,LEVOCETIRIZINE,
AZELASTINE,MIZOLASTINE,EBASTINE,RUPATADINE. Mechanism of action of 2nd generation antihistaminics-
These drugs competitively antagonize actions of
histamine at the H1 receptors.
Pharmacological actions-
Antagonism of histamine-The H1 antagonists effectively block histamine induced bronchoconstriction, contraction of intestinal and other smooth muscle and triple response especially wheal, flare and itch. Constriction of larger blood vessel by histamine is also antagonized.
2) Antiallergic actions-Many manifestations of immediate hypersensitivity (type I reactions)are suppressed. Urticaria, itching and angioedema are well controlled.3) CNS action-The older antihistamines produce variable degree of CNS depression.But in case of 2nd gen antihistaminics there is less CNS depressant property as these cross BBB to significantly lesser extent.
4) Anticholinergic action- many H1 blockers
in addition antagonize muscarinic actions of ACh. BUT IN 2ND gen histaminics there is Higher H1 selectivitiy : no anticholinergic side effects
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
1. Improving Outcomes in the NHS
Professor Sir Mike Richards
The King‟s Fund
November 2012
1
2. Improving outcomes in the NHS:
Overview
● A quick look back
Where were we when the NHS was around 50 years old
(i.e. late 1990s)?
● What happened between 50 and 60 years?
● What is the NHS doing to improve quality at age 64
(i.e. now)?
2
3. The NHS in the late 1990s
● Pride and complacency were increasingly being
challenged (“we have the best health service in the
World”) as evidence grew to the contrary
● Very long waits across almost all specialties (cardiac,
cancer, A&E, orthopaedics, etc)
● Low investment compared to other developed
countries
3
4. The Liam Donaldson question (1999)
LD to MR at an NHS Executive Board meeting
“Mike, can you name me a single service which
has been failing across the NHS and which has
been turned around?”
4
5. The Liam Donaldson question - response
MR to LD: “Yes, cervical cancer screening in 1988”
5
6. The Liam Donaldson question - response
MR to LD: “Yes, cervical cancer screening in 1988”
LD to MR: “Ok, but what about a major service?”
6
7. The NHS between 2000 and 2010 (1)
● A period of
Financial growth
Strategies, national service frameworks, targets, etc
New organisations (e.g. NICE)
New clinical leadership (National Clinical Directors)
New approaches to service improvement
First steps on choice and competition
Increasing emphasis on data to drive change
New emphasis on quality
7
8. The NHS between 2000 and 2010 (2)
● Progress was undoubtedly made
Workforce and facilities have expanded/improved
Waiting times have fallen markedly (cancer, cardiac, A&E,
18 weeks, diagnostics)
Service organisation has improved
• Multidisciplinary team working
• Coordination through networks
• Some reconfiguration (e.g. Cancer, stroke, vascular)
Service improvement approaches are now better (but not
fully) established
8
9. The NHS between 2000 and 2010 (3)
● Improved data collection
e.g. National clinical audits
National Cancer Intelligence Network
● Improved accrual to clinical trials
• Through clinical research networks
● Improved safety
• Hospital acquired infections, VTE, intrathecal chemotherapy
● Reduced smoking prevalence (from 28% to around 20%)
9
10. Progress on outcomes 2000 – 2010?
● Mortality from most of the „big killers‟ has improved
(cancer, cardiovascular, respiratory), but we could still
do a lot better
● Liver mortality is increasing, against the trends in
some other countries
● Diabetes in increasing and could have a major
negative impact on cardiovascular mortality
● Cancer survival in the UK still lags behind that in other
countries
10
11. ICBP: 5 year relative survival. Coleman et al, Lancet 2011
70
20
AUS CAN SWE NOR DEN UK CAN
AUS 18
65
AUS
CAN
16
SWE SWE
60
NOR 14
NOR
DEN 12
55
UK
DEN
10
50 UK
8
45 6
1995-99 2000-02 2005-07 1995-99 2000-02 2005-07
Colorectal Cancer 5yr RS Lung Cancer 5yr RS
90 45
SWE
AUS CAN
85
CAN NOR
40
NOR
AUS
DEN
80
UK
UK
DEN
35
75
70 30
1995-99 2000-02 2005-07 1995-99 2000-02 2005-07
AUS Breast Cancer NOR
CAN SWE 5yr RS DEN UK AUS Ovarian
CAN Cancer 5yrDEN
NOR RS UK
12. ICBP: 1 year relative survival. Coleman et al, Lancet 2011
90 45
SWE
AUS CAN SWE NOR DEN UK
CAN
85 AUS 40
SWE AUS
CAN NOR
80 35
NOR DEN
DEN UK
75 30
UK
70 25
65 20
1995-99 2000-02 2005-07 1995-99 2000-02 2005-07
Colorectal Cancer 1yr RS Lung Cancer 1yr RS
100 80
SWE NOR
75
98
CAN
CAN
AUS
70
AUS
96 DEN
NOR
65
DEN UK
94
UK 60
92
55
90 50
1995-99 2000-02 2005-07 1995-99 2000-02 2005-07
AUS BreastSWE
CAN CancerNOR
1yr RSDEN UK
AUS Ovarian Cancer 1yr RS
CAN NOR DEN UK
13. Progress on other outcomes 2000 – 2010?
● Patient experience is broadly static (though improving
for cancer patients, partly because it is being
measured and reported at team/service level)
● Quality of life for patients with long term conditions is
poorly understood as it is only measured in very broad
surveys
13
15. The NHS Outcomes Framework
Question:
How many people here today are confident
that they can name all 5 domains of the
NHS Outcomes Framework?
15
16. Focus on outcomes
What would you want if you were seriously ill? Probably...
● To have your life saved (D1)
● To have a good quality of life thereafter (D2)
● To recover quickly from treatment (D3)
● To have a good experience of care (D4)
● To be treated in a safe environment (D5)
16
17. Priorities for reducing premature
mortality (D1)
● Improving the NHS contribution to prevention of
ill-health (e.g. NHS Healthcheck)
● Earlier diagnosis: „Finding the missing millions‟
● Improving management in the community
● Improving acute services and treatment
● Preventing recurrence after an acute event
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18. Enhancing quality of life for people
with long term conditions (D2)
● Improvements in primary care
● Patient empowerment
● Coordination and continuity of care
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19. Helping people to recover from
episodes of ill health or following
injury (D3)
● Keeping people out of hospital when possible/desirable
● Effective working between primary and secondary care
● High quality efficient hospital care
● Coordination and support following discharge
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20. How will the new system deliver?
● Through...
Clarity of roles within the new system
Empowering commissioners
Engaging clinicians and providers (e.g. through clinical
networks)
Improving data to drive change
Using financial incentives selectively
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21. New organisations and structures
● Department of Health (DH)
● Public Health England (PHE)
● NHS Commissioning Board (NHS CB)
+ Regions + Local Area Teams (LATs)
● Clinical Commissioning Groups (CCGs)
● Local Authorities (LAs)
● Health & Wellbeing Boards (HWBs)
● Commissioning Support Units (CSUs)
● New Improvement Body (nIB)
● Clinical Senates
● Networks (SCNs and ODNs)
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22. Summary
● We have come a long way on improving quality in the
past 10 – 15 years
● We still have a long way to go to equal the best in
Europe (or the World)
● The new focus on outcomes provides us with a new
opportunity, but it will not be easy – especially at a
time of financial austerity
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