The document discusses factors for success and failure in web startups in 2006, noting that while $600 million was invested in "Web 2.0" startups, a single acquisition was for $1.65 billion, and MySpace generates $25 million per month in advertising revenue. It provides case studies of successful startups like MyBlogLog and Amie Street that never raised venture funding. The document concludes with areas of opportunity and attributes of winners like passion and removing friction versus losers who raised too much money or forgot about scaling.