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METASTASIS OF
MALIGNANT
TUMOR
Table of contents
TYPES OF
CANCER
DEFINITION OF
CANCER
METASTASIS &
METASTASIS OF
MALIGNANT TUMOR
MALIGNANT
TUMOR
01 02
03 04
CANCER
01
DEFINITION
● Cancer is also known as
TUMOR
● It is defined as the abnormal
mass of tissue that results
from the excessive growth of
cells.
CANCER
02
TYPES OF
CANCER
TYPES OF TUMOR
TUMOR
BENIGN
Non cancerous and
typically do not spread
to other parts of the
body
MALIGNANT
Cancerous and can invade
surrounding tissues and
spread to distant organs
through metastasis
03
MALIGNANT
TUMOR
MALIGNANT TUMOR
FEATURES
Aggressive, affects and
destroy the function of
the organs
TREATMENT
Surgery, chemotherapy
and radiation therapy
DEFINITION
Uncontrolled growth
of abnormal cells
WHY CALLED?
They invade into nearby
tissues and spread to other
parts of the body
04
METASTASIS AND
METASTASIS OF
MALIGNANT TUMOR
METASTASIS
Definition:
Metastasis is the
spread of cancer cells
from the original
(primary) tumor to
other parts of the
body
Types of Metastasis
Lymphatic
Enters into lymph
nodes and vessels
Direct
Local invasion
into adjacent
structures
Hematogenous
Spread through
blood to distant
sites
DIRECT SPREAD
• Grows directly into nearby body tissues
Benign Dysplasia In-situ Invasive
Spread
into nearby
tissue
DIRECT SPREAD
• Direct extension, or invasion,
means that the primary tumor
grows into tissues or structures
around it.
• Example: prostate cancer can
grow into the bladder
LYMPHATIC SPREAD
• Carcinomas spread mostly by
lymphatics
• Sentinel lymph node is the first
lymph node which receives
lymph flow from the primary
tumor
LYMPHATIC SPREAD
Primary tumor
↓
Lymphatic vessels
↓
Increased tumor cell spread to sentinel lymph node
↓
Spread to distant lymph nodes
↓
Entry into thoracic duct and subclavian vein. Entry into
blood circulation
↓
Distant site metastasis
↓
Multi organ tumor spread
HEMATOGENOUS SPREAD
• It is common in sarcomas but carcinoma of
breast, thyroid, kidney, liver, prostate and
ovary also do metastasize by blood
• Veins are invaded by tumor cells, resulting
in thrombus formation, detachment of its
parts give tumor emboli.
• Arteries : Due to thick wall they are less
penetrated
• Venous invasion follow venous flow
draining the site of neoplasm. Eg : Liver
and Lung
METASIS OF MALIGNANT TUMOR.pptx
METASIS OF MALIGNANT TUMOR.pptx

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METASIS OF MALIGNANT TUMOR.pptx