The document discusses various types of metallic poisoning, focusing primarily on arsenic. It details the sources, symptoms, treatment, and postmortem appearances associated with acute arsenic poisoning, highlighting its rapid toxicity and the need for immediate medical intervention. The document also differentiates between acute and chronic arsenic poisoning and outlines the fatal effects of significant exposure.

1. METALIC POISONING
BY DR. SADIA MEMON
DEPARTMENT OF FORENSIC MEDICINE
INDUS MEDICAL COLLEGE
TANDO MUHAMMAD KHAN

2.  Arsenic
 Mercury
 Lead
 Copper
 Thallium
 Zinc
METALIC POISONING

3. ARSENIC POISONING
 It is a grey substance, non-poisonous,
insoluble water and can not be absorbed in
alimentary canal.

4. SOURCES
1) AS2O3
(Arsenic oxide)
2) Sulphides of
Arsenic
3) Copper
compound of
Arsenic
 Include
 Scheels green
(Copper Arsenite),
 Paris green or
Emrald green
(Copper Aceto
Arsenite)
4) Other Arsenic of
lead
I. Sodium
II. Potassium
III. Organic Compound
White
Crystalline
Powder
Opaque
brittle mass
Yellow
Orpiment(Hartal)
Or Arsenic
trisulphide
AS2S3
Red Realgar
manseal
Or
Arsenic
Disulphide
(AS2S2)

5. ORAL Mixed with sweetmeat, bread,eggs.
Per Vagina for abortion It is possible that arsenic after
absorption from vagina may be excreted in stomach
Through Skin Form of Pastes, Powder, Creams or wound
Inhalation of Fumes Cigarette in which arsenic mixed wit
tobacco
ROUTES

6. TYPES OF ARSENIC
Two Types
1. Acute Arsenic Poisoning
2. Chronic Arsenic Poisoning
Acute Arsenic Poisoning
Sign & SYMPTOMS
3 Forms
1) Gastro-enteric form
2) Sub acute form
3) Narcotic form

7. ACUTE ARSENIC
GASTRO ENTERIC FORM SUB ACUTE NARCOTIC FORM
Death1 to 2 days Death7 to 10 days Death2 to 3 Hrs
Irritant Poisons symptoms
(Burning pain in stomach
esophagus)
Initial acute attack, patient
becomes weak and may die
due to heart failure.
Large dose is ingested.
Headache, vertigo,
Vascular collapse

8. FATAL DOSE
100 to 150 mg or 120 to 200 mg
FATAL PERIOD
2 to 3 hours

9. Treatment of Acute Arsenic
 Stomach washed out with warm water and milk to
remove arsenic particles
 AntitodeHydrated ferric oxide
 I/V injestionDimercaprol

10. Postmortems Appearance
Externally
 Dehyderate
 Cynosed
 Jaundice
 Skin is Wrinkle
 Rigor mortis lasts longer
Internally
 Mouth, pharynx,esophagus (mucus membrane inflamed and ulcerated)
 Larynx, trachea (hemorrhage)
 Lungs (Congested, pulmonary edema)
 Heart (Sub endocardial hemorrhage of venticle)
 Stomach (swollen)
Red Velvet appearancesub mucosal and sub paritonial
hemorrhage

11. THANK YOU...