The document is a program for the 2nd National Conference on Metabolic Bone Disorders taking place on February 15-16, 2011 in London. The conference will bring together experts in fields related to metabolic bone disorders to discuss causes, diagnosis, treatment, and management of conditions like osteoporosis, fractures, and other disorders. Over the two days, there will be keynote speeches and sessions on topics such as pathogenesis of osteoporosis, use of biomarkers, identification and treatment of fractures, management of primary and secondary osteoporosis, and other disorders including Paget's disease and osteomalacia.
This document discusses fracture liaison services (FLS) and their importance in reducing secondary fractures. It notes that in 2010 in Ireland there were over 18,000 new fragility fractures costing €223 million. Without intervention, fractures are projected to increase to over 28,000 by 2025, costing €320 million. The evidence shows that FLS can reduce secondary fractures by 40% and re-fractures by 80%. An FLS systematically identifies, assesses, treats and refers patients over 50 who have experienced a low-trauma fracture to reduce their risk of future fractures. Key components of an FLS include identification of patients, assessment, education, intervention, and integration into orthopedic services.
This finite element analysis compared the biomechanical effects of different corticotomy approaches on tooth movement during maxillary canine retraction. 24 corticotomy models were designed varying the position, distance from the canine, and width of the cuts. The results showed that a distal corticotomy close to the canine resulted in the greatest canine displacement and lowest strain in the periodontal ligament, suggesting it may be the best approach for facilitating canine retraction. As the distance between the corticotomy and canine increased, its biomechanical effects on tooth movement decreased. The width of the cut did not significantly influence the results.
This document describes a technique for selectively intruding overerupted molars in adult patients using a combination of selective alveolar corticotomies and a modified full-coverage maxillary splint with nickel-titanium springs. Two case reports are presented where this approach successfully intruded overerupted maxillary molars within 2.5-4 months without side effects. The technique aims to take advantage of the regional acceleratory phenomenon caused by corticotomies to increase orthodontic treatment efficiency for adult patients who require molar intrusion.
This curriculum vitae summarizes the professional experience and qualifications of Dr. James B. Stiehl. It includes his education, training, appointments, certifications, publications, memberships, awards and more. Dr. Stiehl is an orthopaedic surgeon specializing in adult reconstructive surgery, total joint replacement and revision surgery. He has over 30 years of experience and has held many leadership positions, including directorships and committee roles, at hospitals and in professional societies.
Cods presentation on segmental arch technique /certified fixed orthodontic co...Indian dental academy
This document describes the Department of Orthodontics and Dentofacial Orthopedics at the College of Dental Sciences in Davangere, India. It lists the faculty members and their backgrounds. It also provides information on student activities organized by the department, faculty achievements, alumni relations, and the history and future of the department. The department aims to provide quality orthodontic education and training to students through various academic and research activities. It has grown since its inception in 1998 and looks forward to continued growth and success in the future.
Jc irf /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
This curriculum vitae outlines the professional experience and qualifications of Professor Freih Abuhassan. It lists his current position as Professor of Orthopaedics, Spine Surgery and Pediatric Orthopaedic Surgery at the University of Jordan. It details his medical qualifications including degrees from Egypt and certifications from the UK and Ireland. It provides an overview of his clinical experience in the UK, Ireland, Jordan and Bahrain. It also lists his academic activities, publications, lectures, and memberships in scientific societies.
SCIENTIFIC PROGRAMME - The Romanian Dentistry Congres, 2017Events Partners
The document provides the scientific programme for a conference on June 15-17, 2017. On the first day, there will be lectures in the morning on various topics in dentistry, followed by a book presentation and lunch break. In the afternoon there will be more lectures and oral communications on implantology, endodontics, and other topics. The second day also involves lectures and oral communications covering implantology, orthodontics, periodontics and more. The third day includes posters, workshops, and oral communications from medical assistants and dental technology students.
This document discusses fracture liaison services (FLS) and their importance in reducing secondary fractures. It notes that in 2010 in Ireland there were over 18,000 new fragility fractures costing €223 million. Without intervention, fractures are projected to increase to over 28,000 by 2025, costing €320 million. The evidence shows that FLS can reduce secondary fractures by 40% and re-fractures by 80%. An FLS systematically identifies, assesses, treats and refers patients over 50 who have experienced a low-trauma fracture to reduce their risk of future fractures. Key components of an FLS include identification of patients, assessment, education, intervention, and integration into orthopedic services.
This finite element analysis compared the biomechanical effects of different corticotomy approaches on tooth movement during maxillary canine retraction. 24 corticotomy models were designed varying the position, distance from the canine, and width of the cuts. The results showed that a distal corticotomy close to the canine resulted in the greatest canine displacement and lowest strain in the periodontal ligament, suggesting it may be the best approach for facilitating canine retraction. As the distance between the corticotomy and canine increased, its biomechanical effects on tooth movement decreased. The width of the cut did not significantly influence the results.
This document describes a technique for selectively intruding overerupted molars in adult patients using a combination of selective alveolar corticotomies and a modified full-coverage maxillary splint with nickel-titanium springs. Two case reports are presented where this approach successfully intruded overerupted maxillary molars within 2.5-4 months without side effects. The technique aims to take advantage of the regional acceleratory phenomenon caused by corticotomies to increase orthodontic treatment efficiency for adult patients who require molar intrusion.
This curriculum vitae summarizes the professional experience and qualifications of Dr. James B. Stiehl. It includes his education, training, appointments, certifications, publications, memberships, awards and more. Dr. Stiehl is an orthopaedic surgeon specializing in adult reconstructive surgery, total joint replacement and revision surgery. He has over 30 years of experience and has held many leadership positions, including directorships and committee roles, at hospitals and in professional societies.
Cods presentation on segmental arch technique /certified fixed orthodontic co...Indian dental academy
This document describes the Department of Orthodontics and Dentofacial Orthopedics at the College of Dental Sciences in Davangere, India. It lists the faculty members and their backgrounds. It also provides information on student activities organized by the department, faculty achievements, alumni relations, and the history and future of the department. The department aims to provide quality orthodontic education and training to students through various academic and research activities. It has grown since its inception in 1998 and looks forward to continued growth and success in the future.
Jc irf /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
This curriculum vitae outlines the professional experience and qualifications of Professor Freih Abuhassan. It lists his current position as Professor of Orthopaedics, Spine Surgery and Pediatric Orthopaedic Surgery at the University of Jordan. It details his medical qualifications including degrees from Egypt and certifications from the UK and Ireland. It provides an overview of his clinical experience in the UK, Ireland, Jordan and Bahrain. It also lists his academic activities, publications, lectures, and memberships in scientific societies.
SCIENTIFIC PROGRAMME - The Romanian Dentistry Congres, 2017Events Partners
The document provides the scientific programme for a conference on June 15-17, 2017. On the first day, there will be lectures in the morning on various topics in dentistry, followed by a book presentation and lunch break. In the afternoon there will be more lectures and oral communications on implantology, endodontics, and other topics. The second day also involves lectures and oral communications covering implantology, orthodontics, periodontics and more. The third day includes posters, workshops, and oral communications from medical assistants and dental technology students.
Capacitacion 101 Iglesia de Dios MisioneraJuan Amesty
Este documento presenta una introducción a la Iglesia de Dios Misionera. Explica que el curso "CAPACITACION 101" ayuda a los nuevos miembros a conocer mejor la iglesia, sus valores centrales y la vida cristiana. También resume la historia, propósito, creencias, organización y deseo de la iglesia de servir a otros y llevarlos a Cristo.
Iglesia de Dios Misionera Capacitacion 301Juan Amesty
Este documento describe los valores centrales o "ADN" de la Iglesia de Dios Misionera. Explica que la iglesia se compone de personas y familias como las nuestras. Los seis valores que distinguen a la iglesia son: la humildad, la pasión por el servicio, la autenticidad, la relevancia, la alegría de vivir y la gracia audaz. El documento explora en detalle qué significa cada uno de estos valores y cómo se manifiestan en la vida de los miembros de la iglesia.
This document discusses renal tubular acidosis (RTA), a group of disorders characterized by hyperchloremic metabolic acidosis and tubular dysfunction. It describes the different types of RTA, including distal RTA (type I), proximal RTA (type II), and type IV RTA. Distal RTA is caused by a failure of the distal renal tubules to secrete dietary acid, leading to an inability to maximally acidify urine or generate new bicarbonate. Proximal RTA results from decreased proximal tubular resorption of bicarbonate. Type IV RTA involves defects in distal tubular secretion of hydrogen ions and potassium, causing hyperchloremic metabolic acidosis and hyper
CAPACITACION 301 IGLESIA DE DIOS MISIONERAJuan Amesty
Este documento presenta una introducción al curso "Capacitación" de la Iglesia de Dios Misionera. Explica que el curso ayudará a los nuevos miembros a conocer mejor la iglesia, sus valores centrales (ADN) y la vida cristiana. Luego describe los seis valores centrales de la iglesia, que son la humildad, la pasión por el servicio, la autenticidad, la relevancia, la alegría de vivir y la gracia audaz. El objetivo es que estos valores sean una realidad en la vida de los
CAPACITACION 401 IGLESIA DE DIOS MISIONERAJuan Amesty
Este documento presenta información sobre el rol de los voluntarios en la Iglesia de Dios Misionera. Explica que los voluntarios no son una fuerza laboral gratuita, sino que facilitan milagros mediante el servicio por amor y no por obligación. También destaca que cada persona tiene dones y talentos únicos para contribuir, y anima a los lectores a descubrir sus propias fortalezas a través de un test, para luego servir en áreas acordes a estas. Finalmente, propone un código de honor para los voluntarios, enfocado
Este documento discute el uso creciente de simulaciones y realidad virtual en la educación médica. Factores como la falta de acceso a experiencias clínicas, preocupaciones por la seguridad de pacientes y cambios en las técnicas médicas han llevado al desarrollo de simuladores que van desde videos y programas de computadora hasta maniquíes avanzados. Aunque no reemplazan la enseñanza clínica directa, las simulaciones pueden mejorar las habilidades de los estudiantes de manera segura. El documento concluye
This document discusses bioavailability of drugs through intravenous (IV) and intramuscular (IM) routes of administration. It defines bioavailability and describes factors that influence it like pharmaceutical, patient, and route of administration factors. It explains how bioavailability is measured using pharmacokinetic and pharmacodynamic methods. IV route provides 100% bioavailability while IM is 75-100% depending on factors like drug properties and injection site. High performance liquid chromatography (HPLC) is described as the primary method for bioavailability studies through pharmacokinetic profiling of drug concentration over time.
Cell blocks provide tissue fragments from FNA specimens that are processed into paraffin blocks. This allows examination of histological structure and use of ancillary tests like immunohistochemistry. Cell blocks increase diagnostic sensitivity and specificity compared to cytology alone. They require minimal effort and preserve tissue for second opinions without losing the original smears. The document discusses FNAC and cell block techniques, materials used, advantages like increased cellularity and diagnostic yield, and importance of clinical information for optimal diagnosis.
This document discusses three cases of metabolic bone diseases:
1) A 72-year-old woman with severe thoracic pain was found to have osteoporosis based on imaging and lab results.
2) A 33-year-old woman with generalized bone pain for 3 months had low calcium and phosphate levels, indicating she had osteomalacia likely caused by medication-induced vitamin D deficiency.
3) Gout was briefly discussed regarding its acute attack management and long-term prevention.
This document provides an overview of giant cell tumor, a type of benign bone tumor. It discusses the definition, epidemiology, clinical presentation, investigations, grading, differential diagnosis, and treatment options. Giant cell tumor commonly involves the ends of long bones and is locally aggressive, destroying bone tissue. While benign, it can occasionally metastasize. Treatment typically involves curettage with the use of adjuvants like phenol or bone cement to reduce the high risk of recurrence. Reconstruction of residual defects is often done with bone grafts or cement.
Este documento resume los principales factores externos que afectan a las empresas y la mercadotecnia. Identifica seis factores macroambientales clave: demográficas, económicas, naturales, tecnológicas, políticas y culturales. Explica brevemente cómo cada uno de estos factores influye en las decisiones de mercadotecnia y los negocios. También analiza los factores internos de una empresa, incluidas sus fortalezas, debilidades, oportunidades y amenazas. Finalmente, describe el ambiente de la mercadot
Psychiatry and Physical Health: Monitoring and managing physical health needs...infobipolar
Programa científico de la conferencia de Psychiatry and Physical Health: Monitoring and managing physical health needs in mental health. Más información en www.puedoser.es
The document outlines the schedule and speakers for a Sports Injuries Symposium taking place at Homerton University Hospital. The symposium will cover a range of topics on foot and ankle injuries from 8:30am to 4:30pm, with presentations from experts in orthopaedics, podiatry, physiotherapy, radiology and sports medicine. Practical ultrasound and simulation sessions will also be included. The venue, Homerton University Hospital, is described as a leading hospital for sports injuries and the designated hospital for the 2012 Olympic Games.
The document outlines the schedule for The London Advanced Tuberculosis Course, which takes place over two days. On the first day, the schedule includes presentations on TB epidemiology, diagnosis of various forms of TB, laboratory diagnostic techniques, and workshops on topics like radiology, IGRA testing, and clinical case discussions. The afternoon includes more workshops and a reception. The second day focuses on workshops in the morning on topics like finding and treating TB patients and new entrant screening. Presentations in the afternoon cover interferon gamma release assays, anti-TNF treatment and immunosuppression in TB patients, molecular diagnostic tools, paediatric TB issues, and global aspects of TB control.
This document discusses orthodontic treatment for adults. It notes that there has been an 800% increase in adult orthodontic patients between 1970-1990 due to factors like increased awareness, innovations in appliances, and media exposure. Adult orthodontic treatment presents unique challenges compared to children due to reduced growth potential, periodontal considerations, and need for multidisciplinary care. The document outlines guidelines for comprehensive orthodontic treatment and adjunctive orthodontic treatment in adults.
This document provides an updated definition and guidelines for medication-related osteonecrosis of the jaw (MRONJ) from the American Association of Oral and Maxillofacial Surgeons (AAOMS). It recommends changing the term from bisphosphonate-related osteonecrosis of the jaw (BRONJ) to MRONJ to include cases involving other antiresorptive and antiangiogenic medications. It defines MRONJ as exposed bone in the jaw for over 8 weeks in a patient taking these medications, without radiation or metastasis to the jaw. The document discusses risk factors, potential mechanisms including inhibited bone remodeling and inflammation/infection, and provides guidance on prevention and management based on disease stage.
This document provides an overview and highlights of trends in rheumatology from 2012. It discusses updated guidelines and recommendations for osteoporosis management, the approval and use of belimumab for systemic lupus erythematosus, rituximab for ANCA associated vasculitis, tocilizumab for rheumatoid arthritis, and collagenase clostridium histolyticum for Dupuytren's contracture. It also reviews musculoskeletal ultrasound, challenges with treatment adherence, and new data on bisphosphonates, denosumab, teriparatide, and other drugs.
This one-day symposium at the Royal College of Physicians in London aims to provide information to trainees considering a career in cardiovascular research. The event will explore why to choose an academic career, where to conduct research training and with whom, and how to design studies, write theses and publications, and respond to peer reviews. Speakers include professors from various universities and researchers who will share their expertise on topics like grant applications, ethics committees, statistics, and taking the next steps post-training. The goal is to nurture and inspire the next generation of cardiovascular researchers.
This document provides information about the ninth edition of Apley's System of Orthopaedics and Fractures. It lists the principal authors and contributors, and provides a brief preface and acknowledgements. The book is dedicated to the authors' students, trainees, patients, wives, children and grandchildren. It was first published in 1959 and this ninth edition was published in 2010 by Hodder Arnold.
Apley's system of orthopaedics and fractures 9th edKhai Le Phuoc
This document provides information about the contributors and preface for the 9th edition of Apley's System of Orthopaedics and Fractures. It lists over 30 contributors who provided updates and new chapters for specialized topics. It notes how the book has expanded over editions to include new tests, classifications, imaging techniques, and basic science knowledge. However, it retains the structure first developed by Alan Apley with sections on general orthopaedics, regional orthopaedics, and fractures/injuries. The preface discusses how clinical skills and physical examinations remain important despite advances, and emphasizes that the book is intended to be useful for orthopaedic surgeons of all experience levels.
physical examination of orthopaedic patientyasser Amr
This document provides information about the contributors and preface for the 9th edition of Apley's System of Orthopaedics and Fractures. It discusses how the book has evolved since its first edition in 1959 to accommodate new tests, imaging techniques, and classifications. While much has changed, the structure of General Orthopaedics, Regional Orthopaedics, and Fractures and Joint Injuries has been retained. This edition includes contributions from additional authors and has been updated with new information and illustrations.
Capacitacion 101 Iglesia de Dios MisioneraJuan Amesty
Este documento presenta una introducción a la Iglesia de Dios Misionera. Explica que el curso "CAPACITACION 101" ayuda a los nuevos miembros a conocer mejor la iglesia, sus valores centrales y la vida cristiana. También resume la historia, propósito, creencias, organización y deseo de la iglesia de servir a otros y llevarlos a Cristo.
Iglesia de Dios Misionera Capacitacion 301Juan Amesty
Este documento describe los valores centrales o "ADN" de la Iglesia de Dios Misionera. Explica que la iglesia se compone de personas y familias como las nuestras. Los seis valores que distinguen a la iglesia son: la humildad, la pasión por el servicio, la autenticidad, la relevancia, la alegría de vivir y la gracia audaz. El documento explora en detalle qué significa cada uno de estos valores y cómo se manifiestan en la vida de los miembros de la iglesia.
This document discusses renal tubular acidosis (RTA), a group of disorders characterized by hyperchloremic metabolic acidosis and tubular dysfunction. It describes the different types of RTA, including distal RTA (type I), proximal RTA (type II), and type IV RTA. Distal RTA is caused by a failure of the distal renal tubules to secrete dietary acid, leading to an inability to maximally acidify urine or generate new bicarbonate. Proximal RTA results from decreased proximal tubular resorption of bicarbonate. Type IV RTA involves defects in distal tubular secretion of hydrogen ions and potassium, causing hyperchloremic metabolic acidosis and hyper
CAPACITACION 301 IGLESIA DE DIOS MISIONERAJuan Amesty
Este documento presenta una introducción al curso "Capacitación" de la Iglesia de Dios Misionera. Explica que el curso ayudará a los nuevos miembros a conocer mejor la iglesia, sus valores centrales (ADN) y la vida cristiana. Luego describe los seis valores centrales de la iglesia, que son la humildad, la pasión por el servicio, la autenticidad, la relevancia, la alegría de vivir y la gracia audaz. El objetivo es que estos valores sean una realidad en la vida de los
CAPACITACION 401 IGLESIA DE DIOS MISIONERAJuan Amesty
Este documento presenta información sobre el rol de los voluntarios en la Iglesia de Dios Misionera. Explica que los voluntarios no son una fuerza laboral gratuita, sino que facilitan milagros mediante el servicio por amor y no por obligación. También destaca que cada persona tiene dones y talentos únicos para contribuir, y anima a los lectores a descubrir sus propias fortalezas a través de un test, para luego servir en áreas acordes a estas. Finalmente, propone un código de honor para los voluntarios, enfocado
Este documento discute el uso creciente de simulaciones y realidad virtual en la educación médica. Factores como la falta de acceso a experiencias clínicas, preocupaciones por la seguridad de pacientes y cambios en las técnicas médicas han llevado al desarrollo de simuladores que van desde videos y programas de computadora hasta maniquíes avanzados. Aunque no reemplazan la enseñanza clínica directa, las simulaciones pueden mejorar las habilidades de los estudiantes de manera segura. El documento concluye
This document discusses bioavailability of drugs through intravenous (IV) and intramuscular (IM) routes of administration. It defines bioavailability and describes factors that influence it like pharmaceutical, patient, and route of administration factors. It explains how bioavailability is measured using pharmacokinetic and pharmacodynamic methods. IV route provides 100% bioavailability while IM is 75-100% depending on factors like drug properties and injection site. High performance liquid chromatography (HPLC) is described as the primary method for bioavailability studies through pharmacokinetic profiling of drug concentration over time.
Cell blocks provide tissue fragments from FNA specimens that are processed into paraffin blocks. This allows examination of histological structure and use of ancillary tests like immunohistochemistry. Cell blocks increase diagnostic sensitivity and specificity compared to cytology alone. They require minimal effort and preserve tissue for second opinions without losing the original smears. The document discusses FNAC and cell block techniques, materials used, advantages like increased cellularity and diagnostic yield, and importance of clinical information for optimal diagnosis.
This document discusses three cases of metabolic bone diseases:
1) A 72-year-old woman with severe thoracic pain was found to have osteoporosis based on imaging and lab results.
2) A 33-year-old woman with generalized bone pain for 3 months had low calcium and phosphate levels, indicating she had osteomalacia likely caused by medication-induced vitamin D deficiency.
3) Gout was briefly discussed regarding its acute attack management and long-term prevention.
This document provides an overview of giant cell tumor, a type of benign bone tumor. It discusses the definition, epidemiology, clinical presentation, investigations, grading, differential diagnosis, and treatment options. Giant cell tumor commonly involves the ends of long bones and is locally aggressive, destroying bone tissue. While benign, it can occasionally metastasize. Treatment typically involves curettage with the use of adjuvants like phenol or bone cement to reduce the high risk of recurrence. Reconstruction of residual defects is often done with bone grafts or cement.
Este documento resume los principales factores externos que afectan a las empresas y la mercadotecnia. Identifica seis factores macroambientales clave: demográficas, económicas, naturales, tecnológicas, políticas y culturales. Explica brevemente cómo cada uno de estos factores influye en las decisiones de mercadotecnia y los negocios. También analiza los factores internos de una empresa, incluidas sus fortalezas, debilidades, oportunidades y amenazas. Finalmente, describe el ambiente de la mercadot
Psychiatry and Physical Health: Monitoring and managing physical health needs...infobipolar
Programa científico de la conferencia de Psychiatry and Physical Health: Monitoring and managing physical health needs in mental health. Más información en www.puedoser.es
The document outlines the schedule and speakers for a Sports Injuries Symposium taking place at Homerton University Hospital. The symposium will cover a range of topics on foot and ankle injuries from 8:30am to 4:30pm, with presentations from experts in orthopaedics, podiatry, physiotherapy, radiology and sports medicine. Practical ultrasound and simulation sessions will also be included. The venue, Homerton University Hospital, is described as a leading hospital for sports injuries and the designated hospital for the 2012 Olympic Games.
The document outlines the schedule for The London Advanced Tuberculosis Course, which takes place over two days. On the first day, the schedule includes presentations on TB epidemiology, diagnosis of various forms of TB, laboratory diagnostic techniques, and workshops on topics like radiology, IGRA testing, and clinical case discussions. The afternoon includes more workshops and a reception. The second day focuses on workshops in the morning on topics like finding and treating TB patients and new entrant screening. Presentations in the afternoon cover interferon gamma release assays, anti-TNF treatment and immunosuppression in TB patients, molecular diagnostic tools, paediatric TB issues, and global aspects of TB control.
This document discusses orthodontic treatment for adults. It notes that there has been an 800% increase in adult orthodontic patients between 1970-1990 due to factors like increased awareness, innovations in appliances, and media exposure. Adult orthodontic treatment presents unique challenges compared to children due to reduced growth potential, periodontal considerations, and need for multidisciplinary care. The document outlines guidelines for comprehensive orthodontic treatment and adjunctive orthodontic treatment in adults.
This document provides an updated definition and guidelines for medication-related osteonecrosis of the jaw (MRONJ) from the American Association of Oral and Maxillofacial Surgeons (AAOMS). It recommends changing the term from bisphosphonate-related osteonecrosis of the jaw (BRONJ) to MRONJ to include cases involving other antiresorptive and antiangiogenic medications. It defines MRONJ as exposed bone in the jaw for over 8 weeks in a patient taking these medications, without radiation or metastasis to the jaw. The document discusses risk factors, potential mechanisms including inhibited bone remodeling and inflammation/infection, and provides guidance on prevention and management based on disease stage.
This document provides an overview and highlights of trends in rheumatology from 2012. It discusses updated guidelines and recommendations for osteoporosis management, the approval and use of belimumab for systemic lupus erythematosus, rituximab for ANCA associated vasculitis, tocilizumab for rheumatoid arthritis, and collagenase clostridium histolyticum for Dupuytren's contracture. It also reviews musculoskeletal ultrasound, challenges with treatment adherence, and new data on bisphosphonates, denosumab, teriparatide, and other drugs.
This one-day symposium at the Royal College of Physicians in London aims to provide information to trainees considering a career in cardiovascular research. The event will explore why to choose an academic career, where to conduct research training and with whom, and how to design studies, write theses and publications, and respond to peer reviews. Speakers include professors from various universities and researchers who will share their expertise on topics like grant applications, ethics committees, statistics, and taking the next steps post-training. The goal is to nurture and inspire the next generation of cardiovascular researchers.
This document provides information about the ninth edition of Apley's System of Orthopaedics and Fractures. It lists the principal authors and contributors, and provides a brief preface and acknowledgements. The book is dedicated to the authors' students, trainees, patients, wives, children and grandchildren. It was first published in 1959 and this ninth edition was published in 2010 by Hodder Arnold.
Apley's system of orthopaedics and fractures 9th edKhai Le Phuoc
This document provides information about the contributors and preface for the 9th edition of Apley's System of Orthopaedics and Fractures. It lists over 30 contributors who provided updates and new chapters for specialized topics. It notes how the book has expanded over editions to include new tests, classifications, imaging techniques, and basic science knowledge. However, it retains the structure first developed by Alan Apley with sections on general orthopaedics, regional orthopaedics, and fractures/injuries. The preface discusses how clinical skills and physical examinations remain important despite advances, and emphasizes that the book is intended to be useful for orthopaedic surgeons of all experience levels.
physical examination of orthopaedic patientyasser Amr
This document provides information about the contributors and preface for the 9th edition of Apley's System of Orthopaedics and Fractures. It discusses how the book has evolved since its first edition in 1959 to accommodate new tests, imaging techniques, and classifications. While much has changed, the structure of General Orthopaedics, Regional Orthopaedics, and Fractures and Joint Injuries has been retained. This edition includes contributions from additional authors and has been updated with new information and illustrations.
This document summarizes the history of osteoporosis in Ireland over the past 3 millennia. It discusses key developments like the first use of DXA scanning in 1990, establishment of the Irish Osteoporosis Society in 1996, and current issues like the need for better prevention, earlier diagnosis, and a multidisciplinary approach. It highlights important contributors to the field and their research. Overall, it provides a high-level overview of osteoporosis treatment and management in Ireland from ancient times to the present.
This document summarizes guidelines for treating osteoporosis in patients over 50 from a lecture given in Rome, Italy in 2015. It discusses a 5-step plan for fracture prevention: 1) case finding for those at high risk, 2) risk evaluation using tools like DXA scans and clinical factors, 3) differential diagnosis to identify secondary causes, 4) medical therapy options like calcium/vitamin D supplementation, bisphosphonates, and RANK ligand inhibitors, and 5) follow up. It provides details on evaluating fracture risk, identifying secondary osteoporosis, recommended supplementation and drug therapies, and monitoring treatment effectiveness and safety.
This document provides an overview of metabolic bone diseases with a focus on osteoporosis and Paget's disease. It discusses the clinical approach including history, physical exam, radiological investigations like DXA scans and lab tests. Risk factors, pathophysiology, clinical features and treatment options for osteoporosis like bisphosphonates, teriparatide, and denosumab are explained. Surgical considerations for patients with osteoporosis are also covered. Paget's disease is defined and its etiology, pathophysiology, clinical signs, complications and treatment are summarized. Key references on the diagnosis and management of metabolic bone diseases are listed.
1. The document discusses osteoporosis and provides information on its definition, diagnosis, risk factors, treatment, and management.
2. Key points covered include WHO definitions of osteoporosis, fracture risk assessment tools like FRAX, FDA-approved medications for treatment, importance of calcium and vitamin D supplementation, and lifestyle factors like exercise and nutrition.
3. New and emerging treatments for osteoporosis are discussed, such as denosumab, romosozumab, and abaloparatide, which aim to reduce bone resorption or increase bone formation.
Dr. Rahul VC Tiwari - Fellowship In Orthognathic Surgery - Jubilee Mission Medical College Hospital and Research Center, Thrissur, Kerala - 31st publication IJAR 1st name
- There is no good evidence that orthodontics causes or cures temporomandibular joint dysfunction. Extracting teeth for orthodontic reasons does not inevitably alter a patient's facial profile. Better quality research is still needed in many controversial areas of orthodontics.
The document summarizes information about osteoporosis from a lecture by Dr. Shahjada Selim. It discusses how bone remodeling occurs throughout life, leading to peak bone mass and then age-related bone loss. It defines osteoporosis as a disorder causing fragile bones from low bone mass and deteriorated bone structure. Key points include how osteoporosis is diagnosed using BMD tests and fracture risk tools, treatments include medications to reduce fracture risk, and lifestyle changes can help prevent osteoporotic fractures.
This document discusses osteoporosis and bisphosphonate drug treatment. It provides definitions of osteoporosis, describes how it occurs due to increased bone resorption, and lists its risk factors. Diagnosis involves measuring bone mineral density and assessing fracture risk. Bisphosphonates like alendronate and risedronate are effective treatments but adherence is low. This can increase fracture risk and costs. The document also discusses medication-related osteonecrosis of the jaws, its risk factors, classification system, and the use of serum CTX levels to help prevent this rare complication of bisphosphonate therapy.
1) The study examined the impact of maternal vitamin D status on fetal skeletal development through 3D ultrasound measurements in 424 pregnant women.
2) It found that suboptimal maternal vitamin D status was associated with increased femur cross-sectional area and splaying in utero, resembling signs of rickets.
3) This suggests that ensuring optimal maternal vitamin D levels during pregnancy may be important for proper fetal skeletal development.
Vitamin D Deficiency In Pre Birth Studiesalisonegypt
1) Lower maternal vitamin D status was associated with greater femoral metaphyseal cross-sectional area and higher femoral splaying index in fetuses at 19 weeks and 34 weeks gestation, suggesting maternal vitamin D insufficiency can influence fetal femoral development as early as 19 weeks.
2) Over 30% of mothers had vitamin D levels considered insufficient or deficient. Lower maternal vitamin D levels were related to increased femoral splaying and larger femoral cross-sectional area in fetuses.
3) The findings suggest that improving maternal vitamin D status early in pregnancy through supplementation may help support optimal fetal bone development.
Vita D Perrine Cg Ea At Adherence To Vit D Recommendations Among Us Infants P...alisonegypt
This study examined adherence to vitamin D recommendations among US infants using data from the Infant Feeding Practices Study II from 2005-2007. The researchers estimated the percentage of infants meeting the 2003 and 2008 vitamin D recommendations from the American Academy of Pediatrics at various ages from 1 to 10.5 months. They found that use of oral vitamin D supplements was low, ranging from 1% to 13% regardless of whether infants were breastfed, formula-fed, or mixed-fed. Most infants did not consume adequate amounts of vitamin D according to the 2008 recommendation, suggesting pediatricians should encourage vitamin D supplementation for breastfed and partially breastfed infants.
Vita D Supple Breatfed Infants Pediatrics 2010alisonegypt
This document summarizes a study examining the use of supplemental vitamin D among infants who were breastfed for prolonged periods. The study found that among infants who were predominantly breastfed for at least 6 months, the rate of receiving supplemental vitamin D was only 15.9%. Parental decisions about vitamin D supplementation were significantly associated with whether the parent agreed their pediatrician recommended it and whether they believed breast milk contains all needed nutrition. Educational efforts are needed to increase compliance with guidelines recommending all breastfed infants receive vitamin D supplementation.
Vita D Defic Mothers Newborns Merewood Pediatrics 2010alisonegypt
This study found high rates of vitamin D deficiency in mothers and newborns in Boston, Massachusetts. 58% of infants and 36% of mothers had vitamin D levels below 20 ng/mL. Risk factors for infant deficiency included a deficient mother, winter birth, black race, and a maternal BMI over 35. Prenatal vitamin use was protective against deficiency for both mothers and infants, however 30% of mothers still had low vitamin D levels despite taking prenatal vitamins.
Vita D Defic Insuffic Pregnancy Johnson Am J Perinatol 2010alisonegypt
This study found that vitamin D deficiency and insufficiency are common among pregnant women in the United States, especially for African American and Hispanic women. The study measured vitamin D levels in 154 African American, 194 Hispanic, and 146 Caucasian pregnant women early in their pregnancies. It found that 97% of African American women, 81% of Hispanic women, and 67% of Caucasian women had insufficient or deficient vitamin D levels. African American women were the most likely to have deficiency, while Caucasian women were the most likely to have sufficient levels. Race was identified as the most important risk factor for deficiency or insufficiency.
Vinchon M Sdh In Infants Can It Occur Spontaneously Childs Nerv Sys 2010[1]alisonegypt
This study examines cases of subdural hematoma (SDH) in infants that were considered to have occurred spontaneously rather than from nonaccidental trauma. The study identified 16 cases of spontaneous SDH in infants (SSDHI) from a prospective database that met criteria for lack of trauma history or suspicious findings. Most SSDHI cases involved males and had predisposing factors like macrocephaly, arachnoidomegaly, or obstetric complications. The study aims to better characterize SSDHI and identify risk factors to differentiate it from cases of traumatic SDH caused by nonaccidental injury.
This document discusses trial tactics and techniques based on the advice of experienced litigators. It recommends gaining experience through taking on as many trials as possible in one's early career, even if they are minor cases. While advocacy skills can be learned, experience trying many cases, preferably dozens per year, is the best teacher. Different advocates have different styles as well, so one should not slavishly copy others but develop their own approach. Overall, industry, hard work, and experience are more important than innate talent for most advocates to achieve success.
1) Recent reports in England have outlined issues with forensic science evidence and its presentation in courts, including concerns about biases towards prosecution experts.
2) There is a large funding gap between the prosecution and publicly funded defense, undermining the principle of a fair trial.
3) English courts have been reluctant to assess the reliability and validity of novel scientific techniques, allowing potentially unreliable evidence that has contributed to past miscarriages of justice.
The Next Innocence Project Law Reivew On Sbsalisonegypt
The article discusses shaken baby syndrome (SBS) convictions and new scientific research casting doubt on the forensic significance of the diagnostic triad used to convict hundreds of caregivers. It presents the case of Audrey Edmunds, who was convicted of murder and sentenced to 18 years in prison based solely on expert testimony that an infant suffered from SBS, despite no evidence the caregiver shook the baby. New research has undermined the triad as proof of shaking and removed shaking from the syndrome. However, the criminal justice system has been slow to incorporate this, and triad-based convictions continue regularly. The author argues this constitutes a criminal justice crisis requiring resolution.
This document summarizes the changing role of expert witnesses in court. It discusses how expert witnesses are traditionally expected to say whatever can reasonably support the client's position, rather than provide objective assistance. Courts have taken a more aggressive role in screening out "junk" testimony. One reform is the "gatekeeper" role of judges to exclude dubious expertise, based on criteria like testing and peer review. However, studies show judges rarely discuss these criteria and more often exclude evidence based on relevance or witness qualifications. There is a clash between the legal system's need for settled conclusions and experts' view that some issues have no settled answer. Through screening and cross-examination, the legal process does not always succeed at exposing problematic expert testimony that could lead
Strengthening Forensic Science A Way Station On The Way To Justicealisonegypt
1) The document discusses the need to strengthen forensic science through ongoing validation research to determine which practices are scientifically valid and the limits of their validity.
2) It proposes a series of "validation investigations" be conducted by a respected body like the National Academy of Sciences to determine if certain forensic techniques and theories have already been scientifically validated or not.
3) The validation investigations would examine all prior studies to determine if a technique has been validated, has not been validated, or has been found invalid. This would provide clarity on forensic practices and could reveal issues requiring re-examination of past convictions.
The document discusses the scientific and legal history of shaken baby syndrome. It describes the medical theory behind shaken baby syndrome - that violently shaking an infant can cause subdural hematomas and retinal hemorrhages leading to death. It notes the debate between experts who support the theory and those who are critical of it. The author argues that this is a genuine battle between qualified experts on both sides, and that expert testimony from both sides should be admitted in court under the Daubert and Kumho standards for expert testimony."
This document discusses shaken baby syndrome (SBS) cases and challenges the prevailing assumptions around SBS. It summarizes that shaking alone cannot cause the injuries typically associated with SBS, and that many other causes could result in retinal hemorrhages and subdural hematomas. It provides tips for challenging SBS claims using Daubert motions and expert witnesses in biomechanics, radiology, neurology and pathology that can argue alternative causes. Contact information is given for several medical experts who may be willing to review cases or testify that the injuries were not necessarily caused by shaking.
This case involves a negligence claim brought by L.C. and L.S. against the Ministry of Children and Families regarding their investigation into injuries sustained by L.C.'s infant son, D.C. D.C. was found to have a serious skull fracture and was initially removed from L.C.'s care. The Ministry conducted an investigation but L.C. maintained her innocence. The key issues are whether the Ministry owed a duty of care to L.C. and L.S., whether the Ministry breached the standard of care in its investigation, and whether any breach caused damages.
This document summarizes the growing issue of vitamin D deficiency (DD) in infants and children. It discusses how DD rates have risen significantly in recent decades across diverse populations. Multiple factors are contributing to the problem, including decreased food fortification of vitamin D, more sun avoidance behaviors, increased obesity rates, and longer breastfeeding durations without adequate supplementation. The document outlines how DD can manifest radiographically as softening of the skull and indistinct facial bones in young infants, as well as subtle metaphyseal changes in the long bones that could be mistaken for abuse-related fractures without consideration of the underlying DD.
The Canadian Paediatric Surveillance Program is a national surveillance system that identifies cases of rare diseases in children through the participation of over 2300 pediatricians. A recent study using this program identified over 100 cases of vitamin D deficiency rickets in Canadian children. National surveillance systems are important for collecting epidemiological data on uncommon conditions to answer research questions and guide public health policy. The Canadian Paediatric Surveillance Program provides valuable data and stimulates collaborative research that can improve children's health.
Retinal Bleeding Caused By Accidental Household Trauma
Metabolic Bone Disorders 2011
1. TO R TE
C FO A
O BE D R
Organised by
BE E
R
K R
31 O BI
BO RLY
EA
ST
2nd national conference
Metabolic
Bone
Disorders
2011
Hallam Conference Centre, London
15th & 16th February 2011
40 YEARS OF MEDICAL EDUCATION
2. Objectives
Metabolic Bone Disorders 2011
will bring together leading experts
Metabolic Bone
15th February: Focus on osteoporosis
in the fields of rheumatology,
orthopaedics, geriatric medicine 08.00-08.55 Registration and refreshments
and endocrinology to discuss 08.55-09.00 Welcome and introduction
the central issues and practical CHAIR: Professor Juliet Compston, Professor of Bone Medicine, University of
Cambridge & Honorary Consultant Physician, Addenbrooke’s Hospital, Cambridge
management of metabolic bone
disorders. CAUSES AND DIAGNOSIS OF OSTEOPOROSIS
Participants will benefit from: 09.00-09.40 KEYNOTE ADDRESS:
• A greater understanding of Current understanding of the pathogenesis of
the causes and diagnosis osteoporosis: implications for treatment,
Professor Juliet Compston, Professor of Bone Medicine, University of
of osteoporosis including Cambridge & Honorary Consultant Physician, Addenbrooke’s Hospital, Cambridge
pathogenesis, bone imaging
09.40-10.10 Value of bone markers in osteoporosis: impact on
and biomarkers
disease monitoring and treatment,
• Insights into optimal Dr Nicola Peel, Consultant & Clinical Lead in Metabolic Bone Medicine, Northern
identification, assessment General Hospital, Sheffield
and treatment of fractures in 10.10-10.40 New non-invasive diagnostic techniques for osteoporosis
osteoporosis Dr Jonathan Reeve, Director of Research, Division of Bone Research, University
of Cambridge & Consultant Physician, Addenbrooke’s Hospital, Cambridge
• An update on current and novel
treatment strategies for primary 10.40-10.55 Discussion
and secondary osteoporosis 10.55-11.20 Refreshments
• Reviews of optimal PREVENTION AND MANAGEMENT OF FRACTURES IN
management strategies OSTEOPOROSIS
for other metabolic bone 11.20-11.50 Non-invasive assessment of fracture risk,
disorders including Paget’s Professor Eugene McCloskey, Professor of Adult Bone Disease, University of
Sheffield & Honorary Consultant, Northern General Hospital, Sheffield
disease, cancer-related
disorders, osteomalacia and 11.50-12.20 Identifying patients with vertebral fractures,
hyperparathyroid bone disease Dr Emma Clark, Consultant Senior Lecturer in Rheumatology, University of Bristol
• Instructive case studies on 12.20-12.50 Vertebroplasty and kyphoplasty for vertebral fractures:
management of difficult or indications and best practice,
Dr Richard Edwards, Interventional Radiologist, Gartnavel General Hospital, Glasgow
unusual cases
12.50-13.05 Discussion
Who should attend? 13.05-14.00 Lunch
CHAIR: Professor Roger Francis, William Leech Professor of Geriatric Medicine &
Metabolic Bone Disorders Honorary Consultant Physician, Freeman Hospital, Newcastle-Upon-Tyne
2011 will be of particular
MANAGEMENT OF PRIMARY AND SECONDARY
interest to:
OSTEOPOROSIS
• Bone physicians
14.00-14.30 Secondary osteoporosis: causes, incidence and
• Rheumatologists identification,
• Orthopaedic specialists Dr Karen Walker-Bone, Senior Lecturer & Honorary Consultant in
Rheumatology, University of Sussex
• Geriatricians
14.30-15.00 Treatment of secondary osteoporosis,
• Endocrinologists Dr Peter Selby, Honorary Senior Clinical Lecturer in Medicine & Consultant
• General practitioners Physician, Central Manchester University Hospitals NHS Foundation Trust
• Radiologists 15.00-15.10 Discussion
• Specialist nurses and nurse 15.10-15.30 Refreshments
practitioners 15.30-16.00 Current understanding of male osteoporosis,
Dr Stephen Tuck, Consultant Rheumatologist, James Cook University Hospital,
• Specialists at fracture clinics/ Middlesbrough
falls clinics
16.00-16.30 Non-pharmacological interventions for osteoporosis,
• Care of the elderly specialists Professor Roger Francis, William Leech Professor of Geriatric Medicine &
Honorary Consultant Physician, Freeman Hospital, Newcastle-Upon-Tyne
• Physiotherapists
• Rehabilitation specialists 16.30-17.00 Advances in medical management of osteoporosis,
Professor Jon Tobias, Professor of Rheumatology, Bristol University
• All trainees in these disciplines
17.00-17.15 Discussion and close of day one
3. e Disorders 2011
16th February: Focus on other metabolic bone disorders
08.30-09.00 Registration and refreshments
CHAIR: Professor David Reid, Head of Division of Applied Medicine & Professor of
Rheumatology, University of Aberdeen
MANAGEMENT OF OTHER METABOLIC BONE
DISORDERS
09.00-09.30 Management of malignant hypercalcaemia,
Professor William Fraser, Professor of Clinical Chemistry & Head of Metabolic
Bone Disease Unit, University of Liverpool
09.30-10.00 Beyond bisphosphonates: new therapies for cancer-
related bone disorders,
Professor Rob Coleman, Professor of Medical Oncology, Weston Park
Hospital, Sheffield
10.00-10.30 Prevention and management of glucocorticoid-induced
bone disorders,
Professor David Reid, Head of Division of Applied Medicine & Professor of
Rheumatology, University of Aberdeen
10.30-10.45 Discussion
10.45-11.10 Refreshments
11.10-11.40 Management of Paget’s disease and its complications,
Dr Richard Keen, Consultant Rheumatologist & Honorary Senior Lecturer in
Metabolic Bone Disease, The Royal National Orthopaedic Hospital, Stanmore
11.40-12.10 Osteomalacia in adults,
Dr Colin Paterson, Late Reader in Medicine, University of Dundee Testimonials from
12.10-12.20 Discussion Metabolic Bone
12.20-13.10 Lunch Disorders 2009
CHAIR: Dr Richard Keen, Consultant Rheumatologist & Honorary Senior Lecturer in
Metabolic Bone Disease, The Royal National Orthopaedic Hospital, Stanmore
“Very informative
13.10-13.40 Hypophosphataemic rickets, meeting: excellent
Dr Jeremy Allgrove, Consultant in Paediatric Endocrinology and Diabetes, Barts overview of metabolic
and the London NHS Trust
bone diseases”
13.40-14.10 Hyperparathyroid bone disease,
Dr Gavin Clunie, Consultant Rheumatologist, The Ipswich Hospital NHS Trust
“Excellent meeting
14.10-14.20 Discussion with the highest calibre
14.20-14.40 Refreshments speakers”
14.40-15.10 The promise of vitamin D and its analogues,
Dr Frazer Anderson, Senior Lecturer in Geriatric Medicine, University of “Very well put together
Southampton
programme covering
15.10-15.15 Discussion most of the important
INSTRUCTIVE CASE STUDIES SESSION aspects of metabolic
bone disease”
15.15-15.45 Osteoporosis: difficult cases,
Dr Gavin Clunie, Consultant Rheumatologist, The Ipswich Hospital NHS Trust Organised by
15.45-16.15 Paget’s disease: difficult cases,
Dr Ashok Bhalla, Consultant in Rheumatology & Metabolic Bone Disease, Royal
Hospital for Rheumatic Diseases NHS Foundation Trust, Bath
16.15-16.45 Rare metabolic bone disorders: difficult cases,
Dr Michael Murphy, Senior Lecturer in Biochemical Medicine, Ninewells
Hospital & Medical School, Dundee
16.45-17.00 Panel discussion
17.00 Close of conference
4. Organised by
Metabolic Bone Disorders 2011
Tuesday 15th & Wednesday 16th February 2011 | Hallam Conference Centre, London
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