Meconium aspiration syndrome (MAS) occurs when meconium, the first fecal matter of newborns, is inhaled or aspirated into the lungs around the time of birth. It affects approximately 15 million newborns annually and can lead to respiratory distress and complications. Factors that increase the risk of meconium passage before birth include fetal distress, postmaturity, and maternal health conditions. Diagnosis is based on symptoms of respiratory distress and presence of meconium below the vocal cords. Treatment focuses on supportive care of respiratory symptoms through oxygen therapy, ventilation if needed, and treatment of complications like pulmonary hypertension. Prevention efforts include monitoring high risk mothers and suctioning the mouth and throat of infants immediately