Student of science and technology Yemen

1. Clinical features
Maternal Effects :
 Cyclical spiking pyrexia which associated with miscarriage and preterm labour.
Anemia.
Hypoglycemia is common.
Pulmonary oedema.
Juandice and Renal Failure due to Hemolysis.
Flu-like Symptoms

2. Fetal Effects :
Abortion.
Premature delivery.
FGR
LBW
Stillbirth.
Neonatal Mortality.

3. Management
Dxiagnosis :
Microscopic >>> thick and thin blood smear is gold standard for Dx
Malarial-specific antigens are now being used for rapid diagnostic test.

4. Treatment :
Most frequent use antimalarial drugs :
 ByWHO; Artemisinin for uncomplicated falciparum malaria.
 By CDC ; for chloroquine-sensitive P.vivax or P.ovale shouled be treated with
chloroquine throughout pregnancyThen primaquine postpartum.
 ByWHO; at least two treatment doses of SULFADOXINE –PYRIMETHAMINE in the
second and third trimesters as a intermittent prevention.

5. Prevention and Chemoprophylaxis :
For malaria control relies on chemoprophylaxis when traveling to or living in endemic areas.
For vector control is also use insecticide-treated netting, pyrethoid insecticides.
For travelers to areas with chloroquine-resistant P.falciparum MEFLOQUINE remains the
only chemoprophylaxis recommended.
∆ : PRIMAQUINE and DOXYCYCLINE are contraindicated in pregnancy, but no sufficient
data onATOVAQUONE and PROGUANILto recommened them.

6. Thank You for
Attention..