This document discusses the benefits of silence based on teachings from ancient Sanskrit texts. It provides several reasons why silence is recommended during certain activities like defecation, urination, sexual intercourse, bleeding, cleaning teeth, and eating. Silence allows one to focus on internal processes and avoid external distractions. It is seen as a preliminary step toward achieving true inner silence and peace. Maintaining silence can also provide practical benefits, as inappropriate speech can lead to problems while silence allows one to remain free. Overall, the document emphasizes that our ancestors understood the importance of regulating speech and embracing silence.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. It is interesting to see how speech
reflects the mind of a person and in
turn how regulation of the process of
speech has beneficial influence on
mind!
One of the shlokas (verses in Sanskrut)
says,
3. PAPENAIVA NRUNAANAM
VAANEE BHAVET
KATUKABHASHINEE
DAINYA MAATSARYA
PARAMAA
SHUBHAASHUBHAVIVARJITA
Meaning:
It is because of diseased mind with
utmost lowliness and jealousy that the
speech becomes scalding with no
concern whatsoever for about the
welfare or otherwise of the listener.
In Geeta it is said,
4. ANUDVEGAKARAM VAAKYAM
SAYAM PRIYA HITAN CHA YAT
SVAADHYAAYAABHYASAN
CHAIVA VANGMAYM TAPA
UCCHYATE
GEETA 17.15
Meaning:
Speech which does not humiliate and
thereby hurt the listener is true and
pleasant and beneficial; is really the
product of penance involving the entire
neurophysiological and neuromuscular
processes of speech and articulation
respectively.
5. There is another shloka which
advocates silence during certain
physiological acts.
UTSARGE MAITHUNE CHAIVA
PRASTRAVE DANTADHAAVNE
SHRAADDHE BHOJANAKALE
CHA
SHATSU MAUNAM
SAMAACHARET
Meaning:
During defecation, urination, removal
of secretions (dirt) of nose, skin, ear
and eyes, during sexual intercourse,
6. during bleeding, cleaning of teeth,
during SHRAADDHA (ritual
performed to commemorate pay
homage to the forefathers, on the
occasion their death anniversary) and
while eating food one should observe
silence i.e. speechlessness.
During defecation usually there is
breath holding and contraction of
abdominal muscles. This is essential
for building adequate pressure in the
abdomen so as to move the feces
towards anus. Due to talking the breath
holding ceases and the abdominal
7. muscles also relax and distraction is
caused creating difficulty in
defecation.
Urination also involves increase in
pressure in the abdomen and also in
the urinary bladder. Talking can alter
these pressures and hence the urinary
flow can be disturbed.
When we are removing the secretions
from nose [respiratory secretions],
skin, ears and eyes we should be
careful to remove the dirt carefully so
as to avoid trauma to theses structures
8. In general, all the excretory processes,
viz. defecation, urination, respiratory
secretions, sweating, secretions in the
ear and eye involve autonomic nervous
activity linked with reticular formation
in the brain. Talking can alter
respiration, activity of reticular
formation, and activity of mind,
autonomic nervous activity, endocrine
and metabolic activity and also the
excretory activity.
Sexual intercourse invariably involves
autonomic activity and hence it is
9. strongly recommended that silence is
observed during sexual intercourse. It
is important because the intensity of
the emotional integration and depth of
ecstasy are apparently hindered due to
talking during sexual intercourse.
Bleeding can either be physiological
bleeding as in case of menstrual
bleeding or trauma [injury].
The process of bleeding and arrest of
bleeding are tremendously influenced
by cardiovascular activity, which in
turn is influenced by autonomic
10. nervous activity. Hence talking that
disturbs autonomic activity is
recommended to be avoided.
During cleaning of the teeth there is a
prayerful attitude with respect to the
plants or herbs used in the process. So
talking is avoided. But from practical
point of view, talking during cleaning
of teeth and gums can cause
inadvertent biting of fingers or injury
to the oral cavity.
During SHRAADDHA silence is
probably advised solely for
11. maintaining pious atmosphere, which
is understandable.
During eating the silence advised to
avoid vulgar and even mundane
thoughts being articulated [thereby
hindering the sanctity of the eating] on
the one hand and to avoid accidental
regurgitation of food in the trachea on
the other.
It can be seen how thoughtful our
ancestors were; with respect to
understanding of life! It has to be
appreciated these are relatively
12. superficial aspects of keeping silence.
There may be more explanations as
well.
Learning to keep silence in terms of
avoiding talk is a very preliminary
process of achieving real silence,
which is called KARMANI AKARMA
in Geeta [4.18], and which is full of
peace and activity. It is very real and
deepest personal experience and also
the cosmic phenomenon that links one
with the universe.
14. If we keep quiet for sometime, then we
can easily observe the turbulence of
thoughts, which keep on crowding our
minds. This observation tells us that
the thoughts are neither our creation
nor are restricted to our body. They are
the results of the interactions between
cosmos and us and illustrate the
continuity between an individual and
the universe.
Keeping silence has a humorous and
practical implication also.
15. AATMANO MUKHADOSHENA
BADHYANTE SHUKA SAARIKA
BAKASTATRA NA BDHYANTE
MAUNAM SARVAARTHA
SAADHANAM
Meaning:
Inappropriate [too long, too harsh,
stupid, meaningless, too enticing]
speech is a cause of slavery,
imprisonment or other type of losses.
Ability to remain silent is extremely
beneficial. This is clear from the
examples of SAARIKA and parrot that
are caught and kept in cage whereas
crane is left free! Hence while
16. negotiating in business or in politics or
even playing cards, silence can play a
pivotal role!
DR. SHRINIWAS KASHALIKAR