an interesting Lupus Quiz

1. LUPUS AWARENESS QUIZ

2. • 4 Rounds
• 2 questions per team in each Round
• Direct Questions +10, No Negative
• Passed Questions +5, No Negative
• POUNCE Rules apply!
• 5 seconds for pouncing for every question
• For POUNCE Answers, PLEASE WRITE THEM DOWN
• +10, -5 for pounce.
• Passed questions can be answered by all others, so WRITE THEM
DOWN
Quiz Rules
Positive Attitude Is
Important in Sports

3. Q1
• Hargraves and others discovered this cell
in bone marrow of lupus patients
• A telltale sign of autoimmune process
but now a forgotten entity
• Name the cell .
• Describe the cell .

4. Q2
He got Nobel prize in medicine and physiology in 1950
He discovered a miracle drug
A 29-year-old female with RA was hospitalized at the Mayo
Clinic left the hospital to enjoy a 3-hour shopping spree by virtue
of this drug .
Which was the compound he discovered ?
Who is this famous scientist ?

5. Q3
Skin biopsy of a lupus patient showed this
immunofluorescence .
What is the pattern ?
Explain the pattern

6. Q4
This is mostly sensitive test for ANA detection in SLE
Often considered as part of entry criteria
What is the test method ?
Which two parameters are used for reporting of ANA
by this test ?

7. Q5
Commonly seen ANA-IF pattern in SLE , MCTD ,
Sjogren syndrome ‘
Can you tell this ANA pattern
Mention any two autoantibodies showing this
pattern

8. Q6
This immunofluorescence test in SLE uses a protozoa
It detects an autoantibody which indicates disease
severity or active nephritis
Which antibody we are talking about ?
What is the name of the test ?

9. Q7
• Two patients’ plasma are being
tested for coagulation
abnormalities.
• The baseline activated Partial
Thromboplastin Time (aPTT) are
prolonged for both of them
• What are the interpretations in
both patients ? ( clue in the
image )

10. Clinical

11. Q1
1% to 3% of patients with cutaneous lupus erythematosus,
Painful subcutaneous hard indurated nodule in skin causing
disfigurement
What is the clinical diagnosis ? What spedific histopathology evidence
do you get ?

12. Q2
• This is one lupus specific rash which is
photosensitive , happens after sun
exposure
This can be induced by medications too
What is the rash ?
Give example of a drug causing this rash

13. Q3
This rash is not specific for SLE
What is the pathological term for
this rash
Name two other disease apart from
lupus having this rash