SINTRA is an informatics system used in Argentina to manage organ, tissue, and stem cell transplantation activities from donor to recipient. It consists of several modules including a national registry for end-stage renal failure patients, organ waiting lists, procurement data, transplantation data, and follow-up information. SINTRA provides traceability throughout the donation and transplantation process, allows for management and auditing of tasks, and guarantees transparency. It is a long-term project that has grown steadily since 2003 to improve coordination between stakeholders and centralize information.