Drug discovery at 2x speed. Faster, more comprehensive testing approval processes. Identifying gene targets in massive sequencing data sets. These goals are ambitious yet attainable, but not without increasing the computational capabilities of today's researchers. While everyone agrees that simply deploying more infrastructure is not the answer, running that work in the cloud is not without challenges. In this talk we will discuss and illustrate elements of those workloads that Cycle Computing's customers have run on AWS, generating vastly better results than would have been attained on traditional infrastructure. We will cover some common problems they encountered, and how they resolved them using Amazon EC2, S3, Glacier, and Cycle's software. Presenters: Dougal Ballantyne, Business Development, AWS; Rob Futrick, CTO, Cycle Computing