A discussion to about strategies and techniques proven to be effective to add value to early stage life science companies. This interactive small group setting provides an opportunity to learn about IP basics, strategies for building an IP portfolio, and the role of IP in corporate transactions. Learn how these IP assets play a role in the value of a company, and how they impact the success a company will have in its capital raising efforts. IP broadly encompasses many different types of corporate assets. Businesses in any industry must be aware of the ways in which the company’s future success can be enhanced by an appreciation of IP and its strategic use.

1. Building Your IP Strategy
Nutter McClennen & Fish LLP
Seaport West
155 Seaport Boulevard
Boston, Massachusetts 02210
Telephone 617.439.2000
nutter.com
November 18, 2014
Michael Curley, Thermedical, Inc.
Heather Repicky, Nutter McClennen & Fish LLP
Derek Roller, Nutter McClennen & Fish LLP

2. What is an IP Strategy?
A roadmap of how IP will support the business
Short
Term
Business
Goals
$
Timing
Long Term
Business
Goals
Marketplace
&
Competitors
Technical
Need
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3. What is an IP Strategy?
An IP Strategy Should Identify:
• Offensive uses of IP – Create barriers to entry for
competitors
• Defensive uses of IP – Keep control of the important
aspects of the business
• IP assets – How the IP portfolio can build value
• IP liabilities – How to avoid potholes
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4. Types of Intellectual Property
• Patents
• Trademarks/Trade Dress
• Copyrights
• Trade Secrets
• Employment Agreements & NDAs
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5. Patents
“Whoever invents or
discovers any new and
useful process, machine,
manufacture or composition
of matter, or any new and
useful improvement thereof,
may obtain a patent . . . . ”
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6. Patents
4 Basic Patent Issues Will Immediately Come Into
Play As You Are Developing Your IP Strategy
• First-to-file system
• 20 year term
• On-sale/Public disclosure bar
• Territorial rights
• $$
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7. First-to-File
• Not necessarily a rush to
USPTO
• IP evaluation system
• File patent
vs.
Defensive publication
• Extra care if under first-to-invent
• Early provisionals an option
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8. Ways to Expedite Patenting Process
• Track One Prioritized
Examination
• Accelerated Examination
• Patent Prosecution Highway
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9. Trademarks and Service Marks
Definition: word, phrase, symbol, or
design that is used to identify the
source of goods/services and to
distinguish them from others
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10. Trademarks and Service Marks
Quick Tips for Trademark Issues:
• Think about developing a brand
• Clear your mark
• Consider filing for trademark registration,
even if you have not begun using the mark
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11. Copyrights
Not just relevant
to painters and novelists.
• Requirements: Original work of author
• Ownership: Author, unless work made for hire
• Open Source Issues
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12. Trade Secrets
Definition: (1) Information that derives an
economic value and is not readily
ascertainable, and (2) reasonable effort
is made to maintain secrecy
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13. Employment Agreements & NDA’s
• Ownership of IP
• Non-competition Agreements (jurisdictional)
• Use of NDAs with vendors/suppliers
• Spend time coming up with a description that
doesn’t reveal your trade secrets but shows
the company value
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14. Saline-Enhanced RF (SERF™) Ablation
A Therapy Platform
Michael G. Curley, Ph.D.
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15. Conventional RF Ablation
RF Current
Heating Field
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16. Conventional RF Ablation
RF Ablation Challenge
Charring at Electrode
Small
Treatment
Volume
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17. Saline Enhanced RF (SERF™) Ablation
Cool Saline
In-line
Saline Heater
Warm
Treats 100 times the volume
Saline Injection
of RF ablation alone
RF Energy
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18. Thermedical Background
SERF™ Ablation for Liver Cancer
• 1.7M liver cancer incidence
• 80% have no therapeutic options
• SERF Ablation will be curative
Platform Technology
SERF System
Liver Cancer Needle
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19. Saline Enhanced RF (SERF™) Ablation
Results: Porcine Liver
RF Only SERF
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20. Ventricular Tachycardia
VT is a fatal arrhythmia
• 600,000 new cases / year
Treated with ICDs
• Painful
• Expensive - costs > $ 75,000
• $ 7B annual WW Market
Preclinical SERF Research
• Transmural lesion demonstrated without
cardiac perforation
SERF will be curative for VT
• Inexpensive - cost < $ 20,000
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21. Thermedical History
$25.00
$20.00
$15.00
$10.00
$5.00
$0.00
Money Raised ($M)
First Meeting on IP Strategy
First US Patent Awarded
Year
Investment
Grants
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22. Discussion Topics
• Development of an IP
strategy
• Use of IP in fundraising
• Working IP into the
culture
• Anticipating changes to
business goals
• Building the portfolio
intelligently
• Role of IP in exit
strategy
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23. Questions?
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