The document summarizes the key components and functions of the endomembrane system in eukaryotic cells. It describes the endoplasmic reticulum, Golgi apparatus, lysosomes, vacuoles, and their roles in protein trafficking, modification and sorting, endocytosis, exocytosis, and various metabolic processes. The endomembrane system regulates transport of proteins and materials between membrane-bound organelles and performs essential functions for cellular maintenance and activity.
Animal cells are typical of the eukaryotic cell, enclosed by a plasma membrane and containing a membrane-bound nucleus and organelles. Unlike the eukaryotic cells of plants and fungi, animal cells do not have a cell wall. This feature was lost in the distant past by the single-celled organisms that gave rise to the kingdom Animalia. Most cells, both animal and plant, range in size between 1 and 100 micrometers and are thus visible only with the aid of a microscope.
All living organisms are made of cells and cellular products. The cell is the smallest structural, functional, and biological unit of all living organisms. It can capable of biosynthesis, replication and energy transformation. All cellular organelles carry out specific functions that are necessary for the normal functioning of the cell. Animal cells work together and function interdependently. Human cells vary in size, shape, and function. Most animal cells are so small they can only be seen with the aid of a microscope. Based on function, there are more than 200 different kinds of animal cells that help each system contribute to the homeostasis of the entire body. Despite their many differences, human cells have several similar structural features: a cell membrane, a nucleus, and cytoplasm and cell organelles.
Animal cells are typical of the eukaryotic cell, enclosed by a plasma membrane and containing a membrane-bound nucleus and organelles. Unlike the eukaryotic cells of plants and fungi, animal cells do not have a cell wall. This feature was lost in the distant past by the single-celled organisms that gave rise to the kingdom Animalia. Most cells, both animal and plant, range in size between 1 and 100 micrometers and are thus visible only with the aid of a microscope.
All living organisms are made of cells and cellular products. The cell is the smallest structural, functional, and biological unit of all living organisms. It can capable of biosynthesis, replication and energy transformation. All cellular organelles carry out specific functions that are necessary for the normal functioning of the cell. Animal cells work together and function interdependently. Human cells vary in size, shape, and function. Most animal cells are so small they can only be seen with the aid of a microscope. Based on function, there are more than 200 different kinds of animal cells that help each system contribute to the homeostasis of the entire body. Despite their many differences, human cells have several similar structural features: a cell membrane, a nucleus, and cytoplasm and cell organelles.
The Endomembrane system is composed of the different membranes that are suspended in the cytoplasm within a eukaryotic cell. These membranes divide the cell into functional and structural compartments, or organelles.
In simple words Endomembrane System is network of single membrane bound cell organelles performing coordinated functions.
THE CELL-Unlocking the Mysteries of the Cell: A Journey into the Building Blo...Nursing Mastery
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Cell :Structure & Functions for Medical and Health allied StudentsRajendra Dev Bhatt
The cell is the basic structural and functional unit of all known living organisms.
It is the smallest unit of life that is classified as a living thing, and is often called the building block of life.
The chapter contain detail descriptions regarding structures and functions of different cell organelles of plant and animal cells which is helpful to UG and PG students of Science. Cell is the basic unit of structure and function in all living organisms. The basic constituents of plant and animal cells are the same,
viz nucleic acid, proteins, carbohydrates, lipids and various inorganic substances
They organized in the same fundamental manner. The shape of plant cell is rectangular and that of animal cell is round with irregular appearance. Cell organelles various membrane bound structures that are
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endoplasmic reticulum etc.
The Endomembrane system is composed of the different membranes that are suspended in the cytoplasm within a eukaryotic cell. These membranes divide the cell into functional and structural compartments, or organelles.
In simple words Endomembrane System is network of single membrane bound cell organelles performing coordinated functions.
THE CELL-Unlocking the Mysteries of the Cell: A Journey into the Building Blo...Nursing Mastery
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Embark on an enlightening voyage into the intricate world of cells with our captivating SlideShare presentation. From the tiniest microorganisms to the complex structures within our bodies, delve into the fundamental units of life that shape our existence.
In this visually engaging presentation, we explore the fascinating realms of cell biology, unraveling the mysteries of cellular structure, function, and diversity. Discover the inner workings of cells, from the powerhouse mitochondria to the information hub of the nucleus, and delve into the dynamic processes that sustain life.
Featuring stunning visuals, insightful explanations, and intriguing facts, our presentation is designed to enlighten and inspire audiences of all backgrounds. Whether you're a seasoned biologist, a curious student, or simply intrigued by the wonders of life, join us on this immersive journey into the heart of the cell.
Unlock the secrets of life itself and gain a deeper appreciation for the remarkable complexity and beauty of the cellular world. Don't miss out on this captivating exploration of "the cell" – the foundation of all living organisms.
Cell :Structure & Functions for Medical and Health allied StudentsRajendra Dev Bhatt
The cell is the basic structural and functional unit of all known living organisms.
It is the smallest unit of life that is classified as a living thing, and is often called the building block of life.
The chapter contain detail descriptions regarding structures and functions of different cell organelles of plant and animal cells which is helpful to UG and PG students of Science. Cell is the basic unit of structure and function in all living organisms. The basic constituents of plant and animal cells are the same,
viz nucleic acid, proteins, carbohydrates, lipids and various inorganic substances
They organized in the same fundamental manner. The shape of plant cell is rectangular and that of animal cell is round with irregular appearance. Cell organelles various membrane bound structures that are
found within a cell such as nucleus, plastids, mitochondria,
endoplasmic reticulum etc.
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Lecture 1 By Hari Yadav Endomembrane system b.sc. 1 sem-.pptx
1. Endomembrane system: protein targeting and
sorting, endocytosis, exocytosis
By: Hari Yadav
M.Sc. (Zoology)
Department of Zoology
School of Biological Sciences
Dr. Hari Singh Gour Central University
Sagar - 470003 Madhya Pradesh, India
3. The endomembrane system
regulates protein traffic and performs metabolic
functions in the cell
• The endomembrane system is composed of membrane bound structures that are suspended in the
cytoplasm of a eukaryotic cell.
• These membranes divide the cell into functional and structural compartments.
• Components of the endomembrane system:
– Nuclear envelope
– Endoplasmic reticulum
– Golgi apparatus
– Lysosomes
– Vacuoles
– Plasma membrane
• These components are either continuous or connected via transfer by
vesicles
4. The Endoplasmic Reticulum: Biosynthetic Factory
• Endoplasmic reticulum (ER) is the largest single membrane
bound intracellular compartment.
• The endoplasmic reticulum (ER) accounts for more than half of
the total membrane in many eukaryotic cells.
• The ER membrane is continuous with the nuclear
envelope.
• There are two distinct regions of ER:-
– Smooth ER, which lacks ribosomes.
– Rough ER, with ribosomes attached on its surface.
5. Smooth ER
Rough ER Nuclear
envelope
Transitional ER
Rough ER
Smooth ER
Ribosomes
Transport vesicle
ER lumen
Cisternae
200 nm
6. Functions of Smooth ER and Rough ER
• The smooth ER
– Synthesizes lipids
– Metabolizes carbohydrates
– Detoxifies poison
– Stores calcium
• The rough ER
– Has bound ribosomes, which secrete glycoproteins (proteins covalently bonded to
carbohydrates)
– Distributes transport vesicles, proteins surrounded by membranes
– Is a membrane factory for the cell
7. • The Golgi apparatus was first discovered in 1897 by Italian physician Camillo
Golgi.
• The Golgi complex , also termed as Golgi body or Golgi apparatus, is a single
membrane bound organelle and part of endomembrane system.
• The Golgi apparatus consists of five to eight flattened membrane bound sacs
called cisternae.
• Functions of the Golgi apparatus:-
– Modifies products of the ER
– Manufactures certain macromolecules
– Sorts and packages materials into transport vesicles
The Golgi Apparatus: Shipping and Receiving Center
8. cis face
(“receiving” side of
Golgi apparatus) Cisternae
trans face
(“shipping” side of
Golgi apparatus)
TEM of Golgi apparatus
0.1 µm
9. Lysosomes: Digestive Compartments
• Lysosomes are single membrane – bound organelles present in animal cells.
• Lysosomes have acidic internal pH (about 5) and are filled with hydrolytic enzymes.
• A lysosome is a membranous sac of hydrolytic enzymes that can digest macromolecules.
• Lysosomal enzymes can hydrolyze proteins, fats, polysaccharides, and nucleic acids.
• Some types of cell can engulf another cell by phagocytosis; this forms a food vacuole.
• A lysosome fuses with the food vacuole and digests the molecules.
• Lysosomes also use enzymes to recycle the cell’s own organelles and macromolecules, a
process called autophagy.
11. Vacuoles: Diverse Maintenance
Compartments
• A plant cell or fungal cell may have one or several vacuoles.
• Food vacuoles are formed by phagocytosis.
• Contractile vacuoles, found in many freshwater protists, pump
excess water out of cells.
• Central vacuoles, found in many mature plant cells, hold organic
compounds and water.
13. Cell Component Structure Function
Concept 6.4
The endomembrane system
regulates protein traffic and
performs metabolicfunctions
in the cell
Endoplasmic reticulum
(Nuclear
Golgiapparatus
Lysosome
Vacuole Large membrane-bounded
vesicle in plants
enzymes (in animalcells)
Stacks of flattened
membranous
sacs; has polarity
(cis and trans
faces)
envelope) sacs; membraneseparates
lumen fromcytosol;
continuous with
the nuclear envelope.
Extensive network of Smooth ER: synthesis of
membrane-bound tubules and lipids, metabolism of carbohy-
drates, Ca2+ storage, detoxifica-
tion of drugs and poisons
Rough ER: Aids in sythesis of
secretory and other proteins
from bound ribosomes; adds
carbohydrates to glycoproteins;
produces new membrane
Modification of proteins, carbo-
hydrates on proteins, and phos-
pholipids; synthesis of many
polysaccharides; sorting of
Golgi products, which are then
released in vesicles.
Membranous sac of hydrolytic Breakdown of ingested sub-
stances cellmacromolecules,
and damaged organelles for
recycling
Digestion, storage, waste
disposal, water balance,cell
growth, and protection
14. Protein Targeting / Sorting
• Protein targeting or protein sorting is the biological mechanism by which
proteins are transported to their appropriate destinations in the cell or outside it.
• Proteins can be targeted to the inner space of an organelle, different intracellular
membranes, plasma membrane, or to exterior of the cell via secretion.
• Proteins synthesized by the cytosolic ribosomes, have a specialized amino acid
sequence attached to them, which decides their fate of translocation into
different organelles.
• These sequences are targeting or sorting sequences, proteins without these signal
amino acids are permanent residents of the cytoplasm and are not transported
anywhere.
• Sorting sinals can be signal peptide.
• Protein translocation may occur co – translationally or post – translationally.
15.
16. Endocytosis
The term endocytosis was given by Christian de Duve in the year 1963.
Endocytosis is a process whereby eukaryotic cells internalize material from their surrounding
environment.
Internalization is achieved by the formation of membrane – bound vesicles at the cell surface that
arise by progressive invagination of the PM, followed by pinching off and release of free vesicles into
the cytoplasm.
Classically, endocytosis has been divided into phagocytosis ( cellular eating ) and pinocytosis (
cellular drinking).
1 Phagocytosis;- Phagocytosis or cell eating describes the internalization of large particles following
particle binding to specific plasma membrane receptors and by the formation of large endocytic vesicles
called phagosomes.
2 Pinocytosis:- Pinocytosis or
cell drinking involves the
ingestion of fluid by the formation
of small endocytic vesicles.
17. Exocytosis
• Exocytosis is the process of moving materials from within a cell to the exterior of
the cell.
• This process requires energy and is therefore a type of active transport.
• Exocytosis is an important process of plant and animal cells as it performs the
opposite function of endocytosis.
• In exocytosis, membrane-bound vesicles containing cellular molecules are
transported to the cell membrane.