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Does surgery for endometriosis improve fertility outcomes? Lakshmi Ravikanti Fellow in Endoscopy and Infertility  Waikato Hospital & Fertility Associates Hamilton Acknowledgment: Mr V P Singh
Burden of Endometriosis ,[object Object]
Is IVF outcome affected in Endometriosis? Endometriosis Vs Tubal – OR 0.56 Severe endometriosis Vs mild endometriosis-OR 0.60 Barnhart et al.FertilSteril.2002
Endometrial Receptivity or Oocyte Quality? Diaz et al. FertilSteril.2000 Healthy Oocyte Donors Healthy recipients Recipients with  Endometriosis III-IV No significant difference in implantation rates or live birth rates Sibling Oocytes Uterine receptivity is NOT impaired
Endometrial Receptivity or Oocyte Quality? Simon C et al. HumRep 1994 Oocyte donors with endometriosis Vs Oocyte donors without endometriosis Significantly lower pregnancy rates from donors with endometriosis So it is likely to be the  Oocyte Quality
Management options for endometriosis related infertility ,[object Object],[object Object],[object Object],[object Object],[object Object]
Expectant management IVF Vs expectant management Soliman et al, Fertil Steril 1993; 59:1239
Endometriosis & COH/IUI Tummon IS et al: Fertil Steril 1997;68: 8-12
Surgery improves the likelihood of spontaneous conception ,[object Object],[object Object],[object Object],[object Object],[object Object],Adamson GD et al,  Am J Obstet  Gynecol 1994; 171:1488 Hughes EG et al,  Fertil Steril;  1993;59:963
ENDO-CAN ,[object Object],[object Object],[object Object],[object Object]
So we know that surgery for endometriosis related infertility is useful for stage 1 & 2 but what about stage 3 & 4? Is it worth the risk? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Fertility outcomes after surgery for stage III / IV Endometriosis (unpublished data) 79.7% 20.3% Total no of cases- 261
 
Fertility outcomes after Laparoscopic excision of grade 3 & 4 endometriosis
Additional Procedures required & Complications  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Summary of outcomes ,[object Object],[object Object],[object Object]
Mrs J Y ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Surgery IVF
Mrs PC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
First Laparoscopy
Wide excision of deep endometriosis  from vagina
Excision of D I E from rectum
Removal of specimen
Excision completed
Suturing of vaginal opening
 
Follow up ,[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object]
THANK YOU

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