This document discusses transboundary waters and provides examples from the La Plata Basin in South America. It notes that the La Plata Basin is unique in that over 45% is located in Brazil while significant portions are also in Argentina, Paraguay, Bolivia, and Uruguay. The basin is home to over 110 million people and accounts for 70% of the GDP of the countries it covers. While cooperation over use of waters has occurred, issues still include extreme weather events from climate change, lack of water quality standards, land use changes, and lack of integrated management.