Knee Prosthesis Development
•
0 likes•216 views
The document describes the development of a magnetorheological knee prosthesis. The prosthesis aims to provide an affordable and functional replacement for the knee joint through the use of magnetorheological fluid. A prototype was constructed to test the design which includes an MR fluid chamber, a resistance barrier to control movement, and a lock beam to prevent hyperflexion. While the mechanism design is complete, control systems still need to be developed and further consideration of energy consumption and magnetic interference is required.
Report
Share
Report
Share
Recommended
ORS 2022-Tibial implant analysis using patient specific data
ORS 2022-Tibial implant analysis using patient specific data Arindam Chakraborty, Ph.D., P.E. (CA, TX)
This document summarizes a study that used patient-specific bone geometry and microstructure data from a μCT scan to create a finite element analysis model comparing tibial implant materials. An iterative process was used to determine the representative volume element cube size to capture bone microstructure properties. A tibial implant geometry was meshed and constant loading was applied to model bone stresses. The results found Von Mises stresses in the bone were below yield limits and stresses were slightly lower for a Co-Cr-Mo implant material versus a Ti-Al material, since Co-Cr-Mo is stiffer. The study concluded that numerical modeling can improve implant design and performance through more tailored, patient-specific evaluations under different conditions.CAVS March Meeting
The document summarizes a research update on bioinspired design from a meeting in March 2010. It discusses testing of porcine aortic walls and valves to obtain experimental data on tensile strength and failure properties. The plan is to use this data to create computational models of the aortic valve and wall using finite element analysis software. CT scans will be used to generate anatomical meshes that can be simulated in the finite element models to study valve opening and closing. The goal is also to build a database of human body finite element models starting with individual organs.
Meshing the Human Lumbar Spine
This document discusses meshing the human lumbar spine for finite element analysis (FEA). It describes how CT scan data was used to generate 3D models of vertebrae in the lumbar spine. Each vertebra was then meshed using techniques like circular lines, shell elements, and solid mapping to create a hybrid mesh. The meshed vertebrae were then connected together along with intervertebral discs. Loads applied to the neck and pelvis allowed large displacement simulation to predict deformation and stresses. An implant was introduced between discs in the FEA model to study stresses before and after a surgical procedure. The meshing techniques allowed NuVasive to use FEA to analyze the human lumbar spine.
Halderman ch096 lecture
The document discusses brake fluid, including its types, specifications, inspection, and testing. It describes the various DOT classifications of brake fluid (DOT 3, 4, 5, 5.1) and their characteristics such as boiling points. The document emphasizes that brake fluid absorbs moisture over time, so it should be changed regularly, such as every two years or 30,000 miles. When inspecting brake fluid, technicians should check the level, color, contamination using test strips or boiling point testers. Brake fluid should not be mixed and the type used must follow manufacturer specifications.
The GREDOR project. Redesigning the decision chain for managing distribution ...
The GREDOR project. Redesigning the decision chain for managing distribution ...Université de Liège (ULg)
This presentation proposes an integrated methodology for redesigning the decision chain in distribution networks for integrating renewable energy and demand side management. Applications of Fluid Mechanics
This document discusses applications of fluid mechanics principles in engineering, including braking systems and lifting devices. It describes how Pascal's principle allows hydraulic braking systems and elevators to function. Anti-lock braking systems and tower cranes are presented as innovations utilizing hydraulics. Wing flap hydraulics are provided as an example of hydraulics in aeronautics. Key fluid mechanics concepts like Pascal's principle, pressure, and Archimedes' principle are defined.
Applications of fluid mechanics
Fluid mechanics has many applications including:
1) Design of systems like canals, dams, turbomachinery and piping systems.
2) Aerodynamics of vehicles and buildings.
3) Use of nanofluids and smart fluids as advanced coolants with enhanced heat transfer properties.
4) Renewable energy technologies such as wind turbines and wave energy converters.
Southern Biomedical Engineering Conference, 9/18/2002
Presentation made to the Southern Biomedical Engineering Conference in Bethesda, MD 9.18.02. An assessment of the importance of micro-environmental variation on resulting stress and strains levels at the microarchitecture of bone.
Recommended
ORS 2022-Tibial implant analysis using patient specific data
ORS 2022-Tibial implant analysis using patient specific data Arindam Chakraborty, Ph.D., P.E. (CA, TX)
This document summarizes a study that used patient-specific bone geometry and microstructure data from a μCT scan to create a finite element analysis model comparing tibial implant materials. An iterative process was used to determine the representative volume element cube size to capture bone microstructure properties. A tibial implant geometry was meshed and constant loading was applied to model bone stresses. The results found Von Mises stresses in the bone were below yield limits and stresses were slightly lower for a Co-Cr-Mo implant material versus a Ti-Al material, since Co-Cr-Mo is stiffer. The study concluded that numerical modeling can improve implant design and performance through more tailored, patient-specific evaluations under different conditions.CAVS March Meeting
The document summarizes a research update on bioinspired design from a meeting in March 2010. It discusses testing of porcine aortic walls and valves to obtain experimental data on tensile strength and failure properties. The plan is to use this data to create computational models of the aortic valve and wall using finite element analysis software. CT scans will be used to generate anatomical meshes that can be simulated in the finite element models to study valve opening and closing. The goal is also to build a database of human body finite element models starting with individual organs.
Meshing the Human Lumbar Spine
This document discusses meshing the human lumbar spine for finite element analysis (FEA). It describes how CT scan data was used to generate 3D models of vertebrae in the lumbar spine. Each vertebra was then meshed using techniques like circular lines, shell elements, and solid mapping to create a hybrid mesh. The meshed vertebrae were then connected together along with intervertebral discs. Loads applied to the neck and pelvis allowed large displacement simulation to predict deformation and stresses. An implant was introduced between discs in the FEA model to study stresses before and after a surgical procedure. The meshing techniques allowed NuVasive to use FEA to analyze the human lumbar spine.
Halderman ch096 lecture
The document discusses brake fluid, including its types, specifications, inspection, and testing. It describes the various DOT classifications of brake fluid (DOT 3, 4, 5, 5.1) and their characteristics such as boiling points. The document emphasizes that brake fluid absorbs moisture over time, so it should be changed regularly, such as every two years or 30,000 miles. When inspecting brake fluid, technicians should check the level, color, contamination using test strips or boiling point testers. Brake fluid should not be mixed and the type used must follow manufacturer specifications.
The GREDOR project. Redesigning the decision chain for managing distribution ...
The GREDOR project. Redesigning the decision chain for managing distribution ...Université de Liège (ULg)
This presentation proposes an integrated methodology for redesigning the decision chain in distribution networks for integrating renewable energy and demand side management. Applications of Fluid Mechanics
This document discusses applications of fluid mechanics principles in engineering, including braking systems and lifting devices. It describes how Pascal's principle allows hydraulic braking systems and elevators to function. Anti-lock braking systems and tower cranes are presented as innovations utilizing hydraulics. Wing flap hydraulics are provided as an example of hydraulics in aeronautics. Key fluid mechanics concepts like Pascal's principle, pressure, and Archimedes' principle are defined.
Applications of fluid mechanics
Fluid mechanics has many applications including:
1) Design of systems like canals, dams, turbomachinery and piping systems.
2) Aerodynamics of vehicles and buildings.
3) Use of nanofluids and smart fluids as advanced coolants with enhanced heat transfer properties.
4) Renewable energy technologies such as wind turbines and wave energy converters.
Southern Biomedical Engineering Conference, 9/18/2002
Presentation made to the Southern Biomedical Engineering Conference in Bethesda, MD 9.18.02. An assessment of the importance of micro-environmental variation on resulting stress and strains levels at the microarchitecture of bone.
Portfolio of Sayeed Mohammed
This document provides a summary of Sayeed Mohammed's professional portfolio. It highlights his experience in mechanical engineering, project management, and product development for medical devices and consumer products. It also lists his educational background, hobbies of travel photography and vlogging, and examples of projects he has led including designing orthopedic screws and an implantable capsule.
WITHWORTH QUICK RETURN MECHANISM .pptx
This document presents a project on designing a novel quick return mechanism composed of a generalized Oldham coupling and slider-crank mechanism. It includes sections on the abstract, introduction, literature review, existing systems, problem identification, proposed system, methodology, cost estimation, results and discussion, references, and conclusion. The project aims to develop a more compact and dynamically balanced alternative to conventional quick return linkages used in machines like shapers. The design is validated through kinematic simulation and experimental testing, with results showing the proposed mechanism is feasible and achieves reasonable accuracy.
643071main niac v2_suit_phase1_ss_120329_forpub
The document describes the Variable Vector Countermeasure Suit (V2Suit) being developed by NASA to address physiological issues associated with long-duration spaceflight such as sensorimotor adaptation and musculoskeletal deconditioning. The V2Suit utilizes gyroscopic properties to provide resistance during movement in microgravity. It has received a patent application and media coverage. Phase 1 work involved initial module design, technology demonstrations, and identifying further research areas like navigation and human factors integration.
Termpaper ai
The document discusses forward and inverse kinematics for humanoid robots. It presents an analytical solution to the forward and inverse kinematics problems for the Aldebaran NAO humanoid robot. The solution decomposes the robot into five independent kinematic chains (head, two arms, two legs). It uses the Denavit-Hartenberg method and solves a non-linear system of equations to find exact closed-form solutions. The implemented kinematics library allows real-time transformations between joint configurations and physical positions, enabling motions like balancing and tracking a moving ball.
Compliant mechanisms and its application in robotics
This document discusses compliant mechanisms. It defines compliant mechanisms as flexible mechanisms that transfer force or motion through elastic body deformation without joints or linkages. The document outlines the advantages of compliant mechanisms over rigid body mechanisms and describes common design techniques like pseudo-rigid body modeling and topology optimization. It provides examples of compliant mechanism applications and concludes with references on the topic.
MAE_207__Endovascular_Project
This document proposes developing a soft, minimally invasive robot capable of maneuvering through the human aorta for medical procedures. It discusses prior research on using shape memory alloys or cables for actuation in medical robots. The planned approach is to fabricate soft robot designs using silicone molding and 3D printing integrated with a fluid control board. The designs will be tested for anchoring capabilities and movement in plastic tubes simulating blood flow resistance.
Design of a Super Twisting Sliding Mode Controller for an MR Damper-Based Sem...
Design of a Super Twisting Sliding
Mode Controller for an MR
Damper-Based Semi-Active
Prosthetic Knee
Computer Assisted Surgical Intervention
A presentation on computer-assisted surgical intervention. Includes a case study on needle insertion.
Compliant_Mechanism-Seminar.pptx
A compliant mechanism is a mechanism that gains at least some of its mobility from the deflection of flexible members rather than from movable joints only. In mechanical engineering, a compliant mechanism is a flexible mechanism that achieves force and motion transmission through elastic body deformation. Compliant mechanisms are all around us, from products we own to high-tech precision manufacturing equipment. You probably use many compliant mechanisms every day. Some examples include one-piece plastic lids (like the one on ketchup bottles), tape measures, battery clips, mouse buttons, and many snap-fit parts. These mechanisms are used to transform motion, forces or energy from input to output. As opposed to rigid-body mechanisms, compliant mechanisms are monolithic and gain at least some of their mobility from the deflection of flexible members rather than movable joints.
IEEE 2014 Java Projects
http://kasanpro.com/projects-list/ieee-2014-java-projects, List of IEEE Java Projects. It Contains the IEEE Projects in the Language Java with ieee publication year 2014
IEEE 2014 Java Projects
List of IEEE Java Projects. It Contains the IEEE Projects in the Language Java with ieee publication year 2014
Electronically integrated active compliant transmission
This section discusses two projects to develop compact piezoelectric actuators for use in an INertially STAbilized Rifle (INSTAR) system. The first project developed an internally leveraged d31 mode actuator called a Recurve actuator that can generate high forces. The second developed an externally leveraged d33 mode actuator using topology optimization to provide high strain. Both actuator designs were fabricated and experimentally validated to meet the force and displacement requirements for the INSTAR system. Power electronics were also developed with a switching amplifier to efficiently drive the actuators. The complete INSTAR system was demonstrated to effectively stabilize the rifle barrel and compensate for user disturbances.
Inherently adaptivestructuralmaterials
The document discusses the design of inherently adaptive structural materials through biomimetics. It outlines examining the structural and adaptive qualities of bone, developing biomimetic principles for adaptive materials, and modeling and validating the structural performance. The presentation includes designing adaptive systems using piezoelectric nanocomposites processed through ionic self-assembly, modeling the behavior at the section and system levels, and preliminary structural evaluation through testing. The goal is to select viable adaptive system architectures and validate the structural principles.
MAE501 Independent Study
Independent study : A Matlab AnyBody interface to compute torque requirements for Assisting and Resisting modes for a leg exoskeleton helping perform a leg curl.
Design optimization of Electromechanical Exoskeleton
This document describes the design optimization of an electro-mechanical exoskeleton. The project aims to optimize the design to minimize power consumption and reduce total mass by selecting appropriate materials and motor angles/velocities. The document outlines the design process, including defining functional requirements, constraints, initial sketches, analysis models, and the multi-phase optimization approach using tools like MATLAB, CES EduPack and Solidworks. The optimization focuses on minimizing the mass of frame materials and power needed for joint movement.
PhillipDaniel_Full_Portfolio
Phillip H. Daniel has experience designing various mechanical and electrical systems. His portfolio includes projects involving an inverted pendulum controller, a adjustable desk design, power electronics for driving motors, and a compliant force sensor integrated into a robot foot. Daniel has strong skills in modeling, simulation, hardware design and implementation, and working on multidisciplinary engineering projects.
WEFT_ResearchBook
This document summarizes research on applying principles from nature to architectural design. It explores concepts like lightness, emergence, and animal architecture found in nature. The research analyzed structural elements from living systems and how to design complex emergent structures from simple elements, similar to biological systems. The goal is to create designs that use less mass and energy through techniques like form-finding and understanding how an organism's properties depend on its growth and environment. The research aims to apply these natural principles to the design of the W.E.F.T. system through digital technologies and fabrication methods.
Kinematic control with singularity avoidance for teaching-playback robot mani...
This article proposes and investigates three methods for avoiding kinematic singularities in a teaching-playback robot manipulator system:
1. Nonredundancy singularity avoidance (NRSA) and redundancy singularity avoidance (RSA) modify the Jacobian matrix to reduce both position and orientation errors or prioritize position error reduction.
2. Point-to-point singularity avoidance (PTPSA) moves the end-effector through singular regions via joint-interpolated control without maintaining position and orientation.
Experimental case studies evaluate the three methods when the end-effector approaches wrist and shoulder singularities. Results show the methods effectively avoid singularities and enhance robot capability for industrial automation.
Fs92 03-015
This document discusses a method for simulating interactions between objects in mechanisms using small-scale interference detection. It represents the contour shapes of objects using molecular models, where molecules prevent overlap between driver and driven objects. It can analyze and synthesize planar kinematic pairs. Examples show it can simulate gears, cams, ratchets, and generateva mechanisms. The method is generalized and automatically optimizes shapes based on functionality plots and molecular time plots. Local shape changes are shown to affect the simulation results.
CV_anish
This document contains the resume of Anish Kumar, a PhD candidate in mechanical engineering at the Indian Institute of Technology Kanpur. It summarizes his education, research interests in dynamics of continuous systems and structural vibrations, publications, academic projects, coursework, and teaching experience. His PhD thesis focuses on the dynamic instability of cylindrical shells under fluctuating radial pressures.
More Related Content
Similar to Knee Prosthesis Development
Portfolio of Sayeed Mohammed
This document provides a summary of Sayeed Mohammed's professional portfolio. It highlights his experience in mechanical engineering, project management, and product development for medical devices and consumer products. It also lists his educational background, hobbies of travel photography and vlogging, and examples of projects he has led including designing orthopedic screws and an implantable capsule.
WITHWORTH QUICK RETURN MECHANISM .pptx
This document presents a project on designing a novel quick return mechanism composed of a generalized Oldham coupling and slider-crank mechanism. It includes sections on the abstract, introduction, literature review, existing systems, problem identification, proposed system, methodology, cost estimation, results and discussion, references, and conclusion. The project aims to develop a more compact and dynamically balanced alternative to conventional quick return linkages used in machines like shapers. The design is validated through kinematic simulation and experimental testing, with results showing the proposed mechanism is feasible and achieves reasonable accuracy.
643071main niac v2_suit_phase1_ss_120329_forpub
The document describes the Variable Vector Countermeasure Suit (V2Suit) being developed by NASA to address physiological issues associated with long-duration spaceflight such as sensorimotor adaptation and musculoskeletal deconditioning. The V2Suit utilizes gyroscopic properties to provide resistance during movement in microgravity. It has received a patent application and media coverage. Phase 1 work involved initial module design, technology demonstrations, and identifying further research areas like navigation and human factors integration.
Termpaper ai
The document discusses forward and inverse kinematics for humanoid robots. It presents an analytical solution to the forward and inverse kinematics problems for the Aldebaran NAO humanoid robot. The solution decomposes the robot into five independent kinematic chains (head, two arms, two legs). It uses the Denavit-Hartenberg method and solves a non-linear system of equations to find exact closed-form solutions. The implemented kinematics library allows real-time transformations between joint configurations and physical positions, enabling motions like balancing and tracking a moving ball.
Compliant mechanisms and its application in robotics
This document discusses compliant mechanisms. It defines compliant mechanisms as flexible mechanisms that transfer force or motion through elastic body deformation without joints or linkages. The document outlines the advantages of compliant mechanisms over rigid body mechanisms and describes common design techniques like pseudo-rigid body modeling and topology optimization. It provides examples of compliant mechanism applications and concludes with references on the topic.
MAE_207__Endovascular_Project
This document proposes developing a soft, minimally invasive robot capable of maneuvering through the human aorta for medical procedures. It discusses prior research on using shape memory alloys or cables for actuation in medical robots. The planned approach is to fabricate soft robot designs using silicone molding and 3D printing integrated with a fluid control board. The designs will be tested for anchoring capabilities and movement in plastic tubes simulating blood flow resistance.
Design of a Super Twisting Sliding Mode Controller for an MR Damper-Based Sem...
Design of a Super Twisting Sliding
Mode Controller for an MR
Damper-Based Semi-Active
Prosthetic Knee
Computer Assisted Surgical Intervention
A presentation on computer-assisted surgical intervention. Includes a case study on needle insertion.
Compliant_Mechanism-Seminar.pptx
A compliant mechanism is a mechanism that gains at least some of its mobility from the deflection of flexible members rather than from movable joints only. In mechanical engineering, a compliant mechanism is a flexible mechanism that achieves force and motion transmission through elastic body deformation. Compliant mechanisms are all around us, from products we own to high-tech precision manufacturing equipment. You probably use many compliant mechanisms every day. Some examples include one-piece plastic lids (like the one on ketchup bottles), tape measures, battery clips, mouse buttons, and many snap-fit parts. These mechanisms are used to transform motion, forces or energy from input to output. As opposed to rigid-body mechanisms, compliant mechanisms are monolithic and gain at least some of their mobility from the deflection of flexible members rather than movable joints.
IEEE 2014 Java Projects
http://kasanpro.com/projects-list/ieee-2014-java-projects, List of IEEE Java Projects. It Contains the IEEE Projects in the Language Java with ieee publication year 2014
IEEE 2014 Java Projects
List of IEEE Java Projects. It Contains the IEEE Projects in the Language Java with ieee publication year 2014
Electronically integrated active compliant transmission
This section discusses two projects to develop compact piezoelectric actuators for use in an INertially STAbilized Rifle (INSTAR) system. The first project developed an internally leveraged d31 mode actuator called a Recurve actuator that can generate high forces. The second developed an externally leveraged d33 mode actuator using topology optimization to provide high strain. Both actuator designs were fabricated and experimentally validated to meet the force and displacement requirements for the INSTAR system. Power electronics were also developed with a switching amplifier to efficiently drive the actuators. The complete INSTAR system was demonstrated to effectively stabilize the rifle barrel and compensate for user disturbances.
Inherently adaptivestructuralmaterials
The document discusses the design of inherently adaptive structural materials through biomimetics. It outlines examining the structural and adaptive qualities of bone, developing biomimetic principles for adaptive materials, and modeling and validating the structural performance. The presentation includes designing adaptive systems using piezoelectric nanocomposites processed through ionic self-assembly, modeling the behavior at the section and system levels, and preliminary structural evaluation through testing. The goal is to select viable adaptive system architectures and validate the structural principles.
MAE501 Independent Study
Independent study : A Matlab AnyBody interface to compute torque requirements for Assisting and Resisting modes for a leg exoskeleton helping perform a leg curl.
Design optimization of Electromechanical Exoskeleton
This document describes the design optimization of an electro-mechanical exoskeleton. The project aims to optimize the design to minimize power consumption and reduce total mass by selecting appropriate materials and motor angles/velocities. The document outlines the design process, including defining functional requirements, constraints, initial sketches, analysis models, and the multi-phase optimization approach using tools like MATLAB, CES EduPack and Solidworks. The optimization focuses on minimizing the mass of frame materials and power needed for joint movement.
PhillipDaniel_Full_Portfolio
Phillip H. Daniel has experience designing various mechanical and electrical systems. His portfolio includes projects involving an inverted pendulum controller, a adjustable desk design, power electronics for driving motors, and a compliant force sensor integrated into a robot foot. Daniel has strong skills in modeling, simulation, hardware design and implementation, and working on multidisciplinary engineering projects.
WEFT_ResearchBook
This document summarizes research on applying principles from nature to architectural design. It explores concepts like lightness, emergence, and animal architecture found in nature. The research analyzed structural elements from living systems and how to design complex emergent structures from simple elements, similar to biological systems. The goal is to create designs that use less mass and energy through techniques like form-finding and understanding how an organism's properties depend on its growth and environment. The research aims to apply these natural principles to the design of the W.E.F.T. system through digital technologies and fabrication methods.
Kinematic control with singularity avoidance for teaching-playback robot mani...
This article proposes and investigates three methods for avoiding kinematic singularities in a teaching-playback robot manipulator system:
1. Nonredundancy singularity avoidance (NRSA) and redundancy singularity avoidance (RSA) modify the Jacobian matrix to reduce both position and orientation errors or prioritize position error reduction.
2. Point-to-point singularity avoidance (PTPSA) moves the end-effector through singular regions via joint-interpolated control without maintaining position and orientation.
Experimental case studies evaluate the three methods when the end-effector approaches wrist and shoulder singularities. Results show the methods effectively avoid singularities and enhance robot capability for industrial automation.
Fs92 03-015
This document discusses a method for simulating interactions between objects in mechanisms using small-scale interference detection. It represents the contour shapes of objects using molecular models, where molecules prevent overlap between driver and driven objects. It can analyze and synthesize planar kinematic pairs. Examples show it can simulate gears, cams, ratchets, and generateva mechanisms. The method is generalized and automatically optimizes shapes based on functionality plots and molecular time plots. Local shape changes are shown to affect the simulation results.
CV_anish
This document contains the resume of Anish Kumar, a PhD candidate in mechanical engineering at the Indian Institute of Technology Kanpur. It summarizes his education, research interests in dynamics of continuous systems and structural vibrations, publications, academic projects, coursework, and teaching experience. His PhD thesis focuses on the dynamic instability of cylindrical shells under fluctuating radial pressures.
Similar to Knee Prosthesis Development (20)
Compliant mechanisms and its application in robotics
Compliant mechanisms and its application in robotics
Design of a Super Twisting Sliding Mode Controller for an MR Damper-Based Sem...
Design of a Super Twisting Sliding Mode Controller for an MR Damper-Based Sem...
Electronically integrated active compliant transmission
Electronically integrated active compliant transmission
Design optimization of Electromechanical Exoskeleton
Design optimization of Electromechanical Exoskeleton
Kinematic control with singularity avoidance for teaching-playback robot mani...
Kinematic control with singularity avoidance for teaching-playback robot mani...
Recently uploaded
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
A proprietary approach developed by bringing together the best of learning theories from Psychology, design principles from the world of visualization, and pedagogical methods from over a decade of training experience, that enables you to: Learn better, faster!
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...rightmanforbloodline
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Complete Newest Version.Top Effective Soaps for Fungal Skin Infections in India
Swisschem Dermacare has mentioned the List of The Best Antifungal Soap In India 2022. All of these soaps are trusted by various Dermatology Experts.
Ketone bodies and metabolism-biochemistry
This slide consists of all the topics of ketone . This can be used for exam purpose for writing about Diabetic keto acidosis etc . Thank you
Histololgy of Female Reproductive System.pptx
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Journal Article Review on Rasamanikya
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
The Best Ayurvedic Antacid Tablets in India
Treat the symptoms of indigestion, heartburn and stomach reflux with the 10 Best Ayurvedic Antacid Tablets in India.
Cell Therapy Expansion and Challenges in Autoimmune Disease
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...rightmanforbloodline
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Versio
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest Version
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kolb, Ian Q. Whishaw, Verified Chapters 1 - 16, Complete Newest VersionTop-Vitamin-Supplement-Brands-in-India List
Swisschem Dermacare provides the Top 10 Vitamin Supplement Brands in India. To know more about us give us call at our official number
Recently uploaded (20)
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
CHEMOTHERAPY_RDP_CHAPTER 6_Anti Malarial Drugs.pdf
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Vestibulocochlear Nerve by Dr. Rabia Inam Gandapore.pptx
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
Promoting Wellbeing - Applied Social Psychology - Psychology SuperNotes
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
TEST BANK For Basic and Clinical Pharmacology, 14th Edition by Bertram G. Kat...
Top Effective Soaps for Fungal Skin Infections in India
Top Effective Soaps for Fungal Skin Infections in India
Cell Therapy Expansion and Challenges in Autoimmune Disease
Cell Therapy Expansion and Challenges in Autoimmune Disease
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
TEST BANK For An Introduction to Brain and Behavior, 7th Edition by Bryan Kol...
Knee Prosthesis Development
- 1. Alejandro LopezValdes Developmentof a MagnetorheologicalKneeProsthesis
- 2. Objective Thedevelopment of a mechanismthatcouldbeimplemented as a substituteforthebasicfunctions of anarticulationsuch as a Knee, in the cases of patientswithtransfemoralamputation. Themechanismseekstosatisfytheneedforanaffordable, functionaland technologicalprostheses.
- 3. Methodology Adquisition of therotationalmovement of theKneeJoint. Designconsiderationstobeimplementedwith a previouslydeveloped MR Fluid. Prototypeconstructionto test mechanism. RotationalMovement MovementVelocityAdjustment Murray et al. (Journal of bone and jointsurgery)
- 4. DesignResults MR. Fluid Chamber. ResistanceBarrier (Mobile) Representation of a programmableelementto determine themovement of thebarrier LockBeamforhyperflexionprevention.
- 7. Control systems are yettobedeveloped.