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A	
  community	
  
extending	
  healthy	
  life	
  
beyond	
  current	
  limits	
  
Thank	
  you!	
  
Healthy	
  
   Happy	
  
123-­‐Year-­‐Old	
  
122	
  
123	
  
          1915	
  
Aging	
  is	
  a	
  cause	
  
Most	
  fatal	
  diseases	
  result	
  from	
  aging	
  
We	
  are	
  treaEng	
  symptoms,	
  	
  
              not	
  causes	
  	
  
Incidence	
  vs.	
  Age	
  
                                            1	
  
  Normalized	
  Occurrence	
  Rate	
  




                                         0.8	
  


                                         0.6	
  


                                         0.4	
  


                                         0.2	
  


                                            0	
  
                                                    0	
     10	
        20	
     30	
       40	
     50	
     60	
     70	
     80	
     90	
  
                                                                                          Age	
  
                                                                                          Age	
  
Cancer:	
  hOp://www.maOstrust.co.uk/incidence/	
  
CVD:	
  hOp://ajcn.nutriEon.org/content/76/1/93.full.pdf+html	
  
Alzheimer’s:	
  hOp://chronopause.com/index.php/2012/04/02/much-­‐less-­‐than-­‐half-­‐a-­‐chance-­‐part-­‐1/	
  
Incidence	
  vs.	
  Age	
  
                                            1	
  
  Normalized	
  Occurrence	
  Rate	
  




                                         0.8	
  


                                         0.6	
  


                                         0.4	
  


                                         0.2	
  


                                            0	
  
                                                    0	
     10	
        20	
     30	
       40	
     50	
     60	
     70	
     80	
     90	
  
                                                                                          Age	
  
                                                                                          Age	
  
Cancer:	
  hOp://www.maOstrust.co.uk/incidence/	
  
CVD:	
  hOp://ajcn.nutriEon.org/content/76/1/93.full.pdf+html	
  
Alzheimer’s:	
  hOp://chronopause.com/index.php/2012/04/02/much-­‐less-­‐than-­‐half-­‐a-­‐chance-­‐part-­‐1/	
  
Incidence	
  vs.	
  Age	
  
                                            1	
  
  Normalized	
  Occurrence	
  Rate	
  




                                         0.8	
  


                                         0.6	
  




                                                            Aging	
  
                                         0.4	
  


                                         0.2	
  


                                            0	
  
                                                    0	
     10	
        20	
     30	
       40	
     50	
     60	
     70	
     80	
     90	
  
                                                                                          Age	
  
                                                                                          Age	
  
Cancer:	
  hOp://www.maOstrust.co.uk/incidence/	
  
CVD:	
  hOp://ajcn.nutriEon.org/content/76/1/93.full.pdf+html	
  
Alzheimer’s:	
  hOp://chronopause.com/index.php/2012/04/02/much-­‐less-­‐than-­‐half-­‐a-­‐chance-­‐part-­‐1/	
  
Funding	
  
	
  
Healthcare:	
   	
   	
   	
   	
   	
  $2,500	
  Billion	
  
Funding	
  
	
  
Healthcare:	
   	
   	
   	
   	
   	
  $2,500	
  Billion	
  
Biological	
  Research:	
   	
  	
  	
  	
  	
  	
  	
  $60	
  Billion	
  
Funding	
  
	
  
Healthcare:	
   	
   	
   	
   	
   	
  $2,500	
  Billion	
  
Biological	
  Research:	
   	
  	
  	
  	
  	
  	
  	
  $60	
  Billion	
  
Biology	
  of	
  Aging:	
   	
   	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  $0.25	
  Bn	
  
Funding	
  
	
  
Healthcare:	
   	
   	
   	
   	
   	
  $2,500	
  Billion	
  
Biological	
  Research:	
   	
  	
  	
  	
  	
  	
  	
  $60	
  Billion	
  
Biology	
  of	
  Aging:	
   	
   	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  $0.25	
  Bn	
  
Applied	
  Biology	
  of	
  Aging:	
  	
  	
  $0.025	
  Bn	
  
	
  
Funding	
  
	
  
Healthcare:	
   	
   	
   	
   	
   	
  $2,500	
  Billion	
  
Biological	
  Research:	
   	
  	
  	
  	
  	
  	
  	
  $60	
  Billion	
  
Biology	
  of	
  Aging:	
   	
   	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  $0.25	
  Bn	
  
Applied	
  Biology	
  of	
  Aging:	
  	
  	
  $0.025	
  Bn	
  
	
  
                  0.001%	
  à	
  1%	
  
Funding	
  
	
  
Healthcare:	
   	
   	
   	
   	
   	
  $2,500	
  Billion	
  
Biological	
  Research:	
   	
  	
  	
  	
  	
  	
  	
  $60	
  Billion	
  
Biology	
  of	
  Aging:	
   	
   	
   	
  	
  	
  	
  	
  	
  	
  	
  	
  $0.25	
  Bn	
  
Applied	
  Biology	
  of	
  Aging:	
  	
  	
  $0.025	
  Bn	
  
	
  
                  0.001%	
  à	
  1%	
  
Prof.	
  Stuart	
  Kim,	
  Stanford	
  
Dr.	
  Judith	
  Campisi,	
  Buck	
  InsEtute	
  
Dr.	
  Oki	
  O’Connor,	
  SENS	
  FoundaEon	
  
Science	
  Pitches	
  
Health	
  Extension	
  Retreat	
  
                             Santa	
  Cruz	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  Jan	
  2-­‐9	
  
Dinelle	
  Lucchesi	
  
Helen	
  Huang	
  
Jason	
  Xu	
  
Minda	
  Myers	
  
Brian	
  Null	
  
Ryan	
  Gibson	
  
Tanya	
  Jones	
  
Alex	
  Carmichael	
  
Adam	
  Sheppard	
  
Lisa	
  BeOs-­‐LaCroix	
  
Joe	
  BeOs-­‐LaCroix	
  
Barrie	
  Robinson	
  
John	
  Schloendorn	
  
Aging	
  Variants	
  Database	
  Project	
  
ScienEfic	
  Ideas	
  




      (cc:	
  AT-­‐SA)	
  Sarah	
  Katzenell	
  
Money	
  
join	
  us!	
  
Ways	
  to	
  get	
  involved	
  
•    AOend	
  a	
  dinner	
  Salon	
  
•    Pitch	
  your	
  project	
  
•    Do	
  research	
  as	
  an	
  intern	
  
•    Pursue	
  a	
  project	
  in	
  our	
  incubator	
  
•    AOend	
  a	
  brainstorming	
  retreat	
  
•    Help	
  at	
  a	
  workshop	
  
        HealthExtension.co	
  
Thank	
  you!	
  
            	
  




joe@HealthExtension.co	
  

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Joe Betts-LaCroix at Health Extension Salon #6

  • 1.
  • 6. Healthy   Happy   123-­‐Year-­‐Old  
  • 8. 123   1915  
  • 9. Aging  is  a  cause  
  • 10. Most  fatal  diseases  result  from  aging  
  • 11. We  are  treaEng  symptoms,     not  causes    
  • 12. Incidence  vs.  Age   1   Normalized  Occurrence  Rate   0.8   0.6   0.4   0.2   0   0   10   20   30   40   50   60   70   80   90   Age   Age   Cancer:  hOp://www.maOstrust.co.uk/incidence/   CVD:  hOp://ajcn.nutriEon.org/content/76/1/93.full.pdf+html   Alzheimer’s:  hOp://chronopause.com/index.php/2012/04/02/much-­‐less-­‐than-­‐half-­‐a-­‐chance-­‐part-­‐1/  
  • 13. Incidence  vs.  Age   1   Normalized  Occurrence  Rate   0.8   0.6   0.4   0.2   0   0   10   20   30   40   50   60   70   80   90   Age   Age   Cancer:  hOp://www.maOstrust.co.uk/incidence/   CVD:  hOp://ajcn.nutriEon.org/content/76/1/93.full.pdf+html   Alzheimer’s:  hOp://chronopause.com/index.php/2012/04/02/much-­‐less-­‐than-­‐half-­‐a-­‐chance-­‐part-­‐1/  
  • 14. Incidence  vs.  Age   1   Normalized  Occurrence  Rate   0.8   0.6   Aging   0.4   0.2   0   0   10   20   30   40   50   60   70   80   90   Age   Age   Cancer:  hOp://www.maOstrust.co.uk/incidence/   CVD:  hOp://ajcn.nutriEon.org/content/76/1/93.full.pdf+html   Alzheimer’s:  hOp://chronopause.com/index.php/2012/04/02/much-­‐less-­‐than-­‐half-­‐a-­‐chance-­‐part-­‐1/  
  • 15. Funding     Healthcare:            $2,500  Billion  
  • 16. Funding     Healthcare:            $2,500  Billion   Biological  Research:                $60  Billion  
  • 17. Funding     Healthcare:            $2,500  Billion   Biological  Research:                $60  Billion   Biology  of  Aging:                        $0.25  Bn  
  • 18. Funding     Healthcare:            $2,500  Billion   Biological  Research:                $60  Billion   Biology  of  Aging:                        $0.25  Bn   Applied  Biology  of  Aging:      $0.025  Bn    
  • 19. Funding     Healthcare:            $2,500  Billion   Biological  Research:                $60  Billion   Biology  of  Aging:                        $0.25  Bn   Applied  Biology  of  Aging:      $0.025  Bn     0.001%  à  1%  
  • 20. Funding     Healthcare:            $2,500  Billion   Biological  Research:                $60  Billion   Biology  of  Aging:                        $0.25  Bn   Applied  Biology  of  Aging:      $0.025  Bn     0.001%  à  1%  
  • 21. Prof.  Stuart  Kim,  Stanford  
  • 22. Dr.  Judith  Campisi,  Buck  InsEtute  
  • 23. Dr.  Oki  O’Connor,  SENS  FoundaEon  
  • 25.
  • 26.
  • 27.
  • 28. Health  Extension  Retreat   Santa  Cruz                          Jan  2-­‐9   Dinelle  Lucchesi   Helen  Huang   Jason  Xu   Minda  Myers   Brian  Null   Ryan  Gibson   Tanya  Jones   Alex  Carmichael   Adam  Sheppard   Lisa  BeOs-­‐LaCroix   Joe  BeOs-­‐LaCroix   Barrie  Robinson   John  Schloendorn  
  • 30.
  • 31.
  • 32.
  • 33. ScienEfic  Ideas   (cc:  AT-­‐SA)  Sarah  Katzenell  
  • 35.
  • 37. Ways  to  get  involved   •  AOend  a  dinner  Salon   •  Pitch  your  project   •  Do  research  as  an  intern   •  Pursue  a  project  in  our  incubator   •  AOend  a  brainstorming  retreat   •  Help  at  a  workshop   HealthExtension.co  
  • 38. Thank  you!     joe@HealthExtension.co