Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2. Contents of this template
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3. Table of contents
Introduction Mental health
About the day Others
You can describe the topic of
the section here
You can describe the topic of
the section here
You can describe the topic of
the section here
You can describe the topic of
the section here
01 02
03 04
4. Whoa!
This can be the part of the
presentation where you can
introduce yourself, write your email…
6. Introduction
You can give a brief description of the
topic you want to talk about here. For
example, if you want to talk about
Mercury, you can say that it’s the smallest
planet in the entire Solar System
7. Do you need longer text?
Mercury is the closest planet to the
Sun and the smallest one in the entire
Solar System. This planet's name has
nothing to do with the liquid metal,
since Mercury was named after the
Roman messenger god. Despite being
closer to the Sun than Venus, its
temperatures aren't as terribly hot as
that planet's
Speaking of craters, many of them
were named after artists or authors
who made significant contributions to
their respective fields. Mercury takes
a little more than 58 days to complete
its rotation, so try to imagine how long
days must be there! Since the
temperatures are so extreme, albeit
not as extreme as in Venus
8. Understanding
mental health
Do you know what helps you make your
point clear? Lists like this:
● They’re simple
● You can organize your ideas
● You’ll never forget to buy milk!
And the audience won’t miss the point of
your presentation
9. Mental health
Supporting mental health
Mental Health Awareness
Mercury is the closest planet to the Sun
and the smallest one in the Solar System
Venus has a beautiful name and is the
second planet from the Sun
11. What does mental health include?
Emotional
well-being
Despite being red,
Mars is cold
Psychological
well-being
Jupiter is the biggest
planet of them all
Social
welfare
Venus has extremely
high temperatures
12. How to maintain a positive
mental health?
Try to think
positive
Saturn is a gas giant
and has several rings
Be physically
active
Jupiter is the biggest
planet of them all
Helping
others helps
Venus is the second
planet from the Sun
Always get
enough sleep
Despite being red,
Mars is a cold place
13. More information
Mercury
Mercury is the closest
to the Sun
Venus
Venus is the second
planet from the Sun
Mars
Despite being red,
Mars is a cold place
Saturn
Saturn is a gas giant
and has several rings
Jupiter
It’s the biggest planet
in the Solar System
Neptune
Neptune is the farthest
from the Sun
19. 1992
Year in which World Mental
Health Day was celebrated for
the first time
20. is Jupiter’s rotation period
9h 55m 23s
Earth’s is the Sun’s mass
333,000
is the distance between Earth and the Moon
386,000km
21. What day is it celebrated?
October
Mo Tu We Th Fr Sa Su
1 2
3 4 5 6 7 8 9
10 11 12 13 14 15 16
17 18 19 20 21 22 23
24 25 26 27 28 29 30
31
October 10
It is the day on which
World Mental Health
Day is celebrated
23. Ages that take the most care of their
mental health
Under 18
years old
Mercury is the
closest to the Sun
75
%
Over 18
years of age
Saturn is a gas giant
and has several rings
25
%
24. Computer
mockup
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the screen with your own
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and select “Replace image”
26. Phone mockup
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the screen with your own
work. Just right-click on it
and select “Replace image”
27. Where do people suffer the most
from mental illness?
Germany
Saturn is a gas giant
and has several rings
South Korea
Despite being red, Mars
is very cold
28. Our team
Jenna Doe
You can speak a bit
about this person here
John James
You can speak a bit
about this person here
29. What to do?
Go to the
professional
Venus is the second
planet from the Sun
01
Diagnosing
illness
Saturn is a gas giant
and has several rings
02
Following
guidelines
Jupiter is the biggest
planet of them all
03
30. Types of mental illness
Anxiety
Saturn is a gas giant and has
several rings
Depression
Despite being red, Mars is cold
Schizophrenia
Venus is the second planet
from the Sun
31. What to do on this day?
Raise awareness
Mercury is the closest planet to the
Sun and the smallest one of them all
Educate
Jupiter is a gas giant and the biggest
planet in the Solar System
Advocate
Venus has a beautiful name and is
the second planet from the Sun
32. Common warning signs
Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
Low energy
Venus is the second
planet from the Sun
35%
Feeling numb
Saturn is a gas giant and
has several rings
30%
Stepping away
Despite being red, Mars
is very cold
10%
Drinking a lot
Jupiter is a gas giant and
the biggest planet
25%
33. Conclusions
Working together with associations
Developing activities
Mercury is the closest planet to the Sun and the
smallest one in the Solar System
Venus has a beautiful name and is the second planet
from the Sun
Supporting equal access
Despite being red, Mars is a very cold place. It’s full of
iron oxide dust
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37. Resources
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● Mental health social media cover
● Mental health social media post
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template
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Photos
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● Medium shot sad woman covering with
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