This document presents an abstract for a thesis about the interaction between built and natural systems. As populations grow and concentrate in cities, these interactions are becoming more important. The thesis will immerse occupants in a series of built typologies expressing different levels of integration with natural ecologies. The St. Johns River system and Jacksonville, FL will serve as the natural and built contexts. A mixed-use development anchored by an ecological center will exhibit and research the river basin through typologies ranging from closed research biomes to open natural areas. The goal is to condense and experience the hydrological and ecological connections of the river system from freshwater headwaters to the brackish mouth.