Leveraging IP intelligence through the researcher workflow requires the curation of chemistry patents including many thousands of molecules. This complex task is time-consuming and error-prone when done manually, whereas using ChemAxon’s ChemCuratora to analyze and extract chemical information in patents and other documents means the process can be done accurately in a fraction of the time.

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See IP differently™
Intellectual property (IP) intelligence solutions designed
for the way researchers think
Cheminfo Stories 2020 Asia-Pacific Edition
Session #3: IP and Markush technology
November 12, 2020

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Agenda
IP-GeoScape®: Medicinal chemistry through the lens of
intellectual property
Real-world example of how IP-GeoScape can be used
• COVID-19 initiative
The impact of ChemAxon’s ChemCurator product on time and
cost savings for IP-GeoScape
Thoughts on the future of IP strategy in research
• The recently launched IP-GeoScape Library

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AI and machine learning-based monetization of
strategic opportunities in biopharma and beyond…
Who is ?
Technology-driven innovation through the
use of intellectual property

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The challenge and the solution
Seeing and
harnessing the full
potential of IP is
hard
Look through
an IP lens
Specific Next Steps
Actionable Insights
Compiled Intelligence
Curated Data
IP solutions designed for the way researchers think

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Other
Relevant
InformationLegal Financial
Business
Development
ScientificR&D
Social
Media
RegulatoryEmployee
We find the IP relevant to a specific
area of interest (a biological target-
receptor, enzyme, ion channel etc.;
drug product or therapeutic area)
and create visuals showing the
structural relationships
Use interactive visualizations
to guide decision-making
Visualizations illustrating the
similarity between IP
Add any additional curated
information as necessary
Our visualizations are
stand-alone or can be accompanied by
in-depth expert analysis, providing a
deeper understanding with
recommendations, and additional
support services
Key IP, research
information, etc. in the area
of interest – publicly available
and/or private data (if
desired)
Intelligence through an IP lens
Create the lens Understand the context Answer the question

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Accencio®’s IP-GeoScape
technology offers a visual
landscape of the subject matter
within IP revealing the structural
relationships that exist
IP-GeoScape®
Current applications include
both small and large molecule
biopharmaceutical industry
analyses
Currently available for
independent use by researchers
and IP professionals through the
IP-GeoScape library, and
customizable upon request

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Each color = specific IP owner
WO-2004….
Each marking = one specific
IP owner compound
Each marking shape = the
specific patent disclosing the
compound
Compounds are clustered
together based on similarity.
Clusters are grouped
together based on similarity
How to read the IP-GeoScape lens

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IP-GeoScape creation
We identify the most
relevant biological
targets which have
the highest potential
for both retargeting
and new molecule
research efforts
Based on the target
and target concept,
we find the relevant
intellectual property
covering the
molecular
structures
We extract the
molecular
structures
exemplified
within the patent
claims
We use our
proprietary
mathematical
approach to cluster
molecules and create
a visual molecular
landscape
Users interested in
the area access the
visualizations and
analysis generated
via our
AccencioView™️
innovation platform
IP-GeoScape® AccessTargets Patents Molecules

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See IP differently™
From patents to treatments: using IP intelligence and
molecular landscaping in the fight against COVID-19

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COVID-19 Initiative
retarget existing molecules
associated with biological targets
not indicated for COVID-19
Accencio is using its IP-GeoScape technology
to quickly and systematically:
drive development of new
therapeutic molecules in known
COVID-19 biological targets
to support the efficient development of
effective COVID-19 treatmentswww.accencio.com/covid

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COVID-19: Where we are now
Retargeted Molecules
New Molecules (R&D)
Complimentary access to our IP-GeoScape
COVID-19 library is available for targets
including viral protease inhibitors, RNA
polymerase inhibitors, TLR7 agonists and
antagonists, and CRCX3
COVID-19 IP-GeoScape Library
New Molecule R&D
The ChemCurator Difference
Extracting structures from the number of
patents involved without ChemCurator
would have taken too long so as to make
the project impossible, and purchasing the
data would have been cost-prohibitive
By using ChemCurator, our extraction times
are reduced by over 95% compared to
manual methods
This efficiency has been critical to the
success of the project and IP-GeoScape as
a whole
https://www.accencio.com/newmolecule.html

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Software
Industry &
IP Agnostic
Artificial
Intelligence
Independent
customization
Custom
generation
Fully
Integrated
-2021
Non-molecular
IP
Beyond
Biopharma
Smart research-data
repository populated
through ML
AI
researcher
-2022
-2023
-2022
-2023
-2022
-2023
Industry-agnostic software
providing AI supported IP
intelligence solutions that have
“learned” how users do the work
they do… therefore predicting and
generating new opportunities and
potential products faster, more
efficiently, and in an on-going,
iterative fashion
The Future

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The IP-GeoScape Library
Where medicinal chemistry and IP meet
Accencio recently
launched its IP-
GeoScape library for
independent use by
researchers
Currently 20 high-value
biological targets
available with more to
come soon!
Are there target(s) of
interest to you not
included yet?…Just ask
and we can create!
https://www.accencio.com/ip-geoscape.html

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Ready to See IP
Differently?
Kevin Brown
kevin.brown@accencio.com
@accencioip
@accencioip
Accencio
Accencio
Get in Touch
+1-484-246-5470
www.accencio.com