Influenza viruses come in four main types: A, B, C, and D. Influenza A and B primarily cause seasonal flu epidemics in humans and can lead to severe illness. Influenza C typically causes mild illness in humans. Influenza D has not been known to cause human illness. The flu spreads through respiratory droplets when infected people cough, sneeze or talk. Common symptoms include fever, cough, sore throat, and body aches. The best prevention methods are the annual flu vaccine, frequent handwashing, and staying home when sick.