This document discusses defining the need for research and formulating an effective research question. It provides examples of both too broad and too narrow research questions and explains how to refine questions. An effective research question should be specific enough to answer but broad enough to have scope. It should also consider who, what, when, where, why and follow a format like "The treatment of sickle cell anemia over the last 100 years and its affect on the quality of life on 30 – 40 year olds suffering from the disease." The document concludes by having students practice writing research questions.